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Items: 1 to 50 of 253

1.

PAN-AMPK Activation Improves Renal Function in a Rat Model of Progressive Diabetic Nephropathy.

Zhou X, Muise ES, Haimbach R, Sebhat IK, Zhu Y, Liu F, Souza SC, Kan Y, Pinto S, Kelley DE, Hoek M.

J Pharmacol Exp Ther. 2019 Oct;371(1):45-55. doi: 10.1124/jpet.119.258244. Epub 2019 Jul 12.

PMID:
31300612
2.

Targeting a ceramide double bond improves insulin resistance and hepatic steatosis.

Chaurasia B, Tippetts TS, Mayoral Monibas R, Liu J, Li Y, Wang L, Wilkerson JL, Sweeney CR, Pereira RF, Sumida DH, Maschek JA, Cox JE, Kaddai V, Lancaster GI, Siddique MM, Poss A, Pearson M, Satapati S, Zhou H, McLaren DG, Previs SF, Chen Y, Qian Y, Petrov A, Wu M, Shen X, Yao J, Nunes CN, Howard AD, Wang L, Erion MD, Rutter J, Holland WL, Kelley DE, Summers SA.

Science. 2019 Jul 26;365(6451):386-392. doi: 10.1126/science.aav3722. Epub 2019 Jul 4.

PMID:
31273070
3.

Misinformation as a Misunderstood Challenge to Public Health.

Southwell BG, Niederdeppe J, Cappella JN, Gaysynsky A, Kelley DE, Oh A, Peterson EB, Chou WS.

Am J Prev Med. 2019 Aug;57(2):282-285. doi: 10.1016/j.amepre.2019.03.009. Epub 2019 Jun 24. No abstract available.

PMID:
31248741
4.

E-Cigarette Outcome Expectancies among Nationally Representative Samples of Adolescents and Young Adults.

Barker JO, Kelley DE, Noar SM, Reboussin BA, Cornacchione Ross J, Sutfin EL.

Subst Use Misuse. 2019 Jun 12:1-10. doi: 10.1080/10826084.2019.1624773. [Epub ahead of print]

PMID:
31188055
5.

Health claims made in vape shops: an observational study and content analysis.

Wagoner KG, Berman M, Rose SW, Song E, Cornacchione Ross J, Klein EG, Kelley DE, King JL, Wolfson M, Sutfin EL.

Tob Control. 2019 May 23. pii: tobaccocontrol-2018-054537. doi: 10.1136/tobaccocontrol-2018-054537. [Epub ahead of print]

PMID:
31123104
6.

Trust in national health information sources in the United States: comparing predictors and levels of trust across three health domains.

Peterson EB, Chou WS, Kelley DE, Hesse B.

Transl Behav Med. 2019 May 22. pii: ibz066. doi: 10.1093/tbm/ibz066. [Epub ahead of print]

PMID:
31116400
7.

Dyadic associations between perceived social support and cancer patient and caregiver health: An actor-partner interdependence modeling approach.

Kelley DE, Kent EE, Litzelman K, Mollica MA, Rowland JH.

Psychooncology. 2019 Jul;28(7):1453-1460. doi: 10.1002/pon.5096. Epub 2019 May 8.

PMID:
30993811
8.

Spatial and temporal studies of metabolic activity: contrasting biochemical kinetics in tissues and pathways during fasted and fed states.

Daurio NA, Wang Y, Chen Y, Zhou H, Carballo-Jane E, Mane J, Rodriguez CG, Zafian P, Houghton A, Addona G, McLaren DG, Zhang R, Shyong BJ, Bateman K, Downes DP, Webb M, Kelley DE, Previs SF.

Am J Physiol Endocrinol Metab. 2019 Jun 1;316(6):E1105-E1117. doi: 10.1152/ajpendo.00459.2018. Epub 2019 Mar 26.

PMID:
30912961
9.

Pharmacological AMPK activation induces transcriptional responses congruent to exercise in skeletal and cardiac muscle, adipose tissues and liver.

Muise ES, Guan HP, Liu J, Nawrocki AR, Yang X, Wang C, Rodríguez CG, Zhou D, Gorski JN, Kurtz MM, Feng D, Leavitt KJ, Wei L, Wilkening RR, Apgar JM, Xu S, Lu K, Feng W, Li Y, He H, Previs SF, Shen X, van Heek M, Souza SC, Rosenbach MJ, Biftu T, Erion MD, Kelley DE, Kemp DM, Myers RW, Sebhat IK.

PLoS One. 2019 Feb 27;14(2):e0211568. doi: 10.1371/journal.pone.0211568. eCollection 2019.

10.

Clinical Evaluation of MK-2640: An Insulin Analog With Glucose-Responsive Properties.

Krug AW, Visser SAG, Tsai K, Kandala B, Fancourt C, Thornton B, Morrow L, Kaarsholm NC, Bernstein HS, Stoch SA, Crutchlow M, Kelley DE, Iwamoto M.

Clin Pharmacol Ther. 2019 Feb;105(2):417-425. doi: 10.1002/cpt.1215. Epub 2018 Sep 30.

PMID:
30125349
11.

GPR119 Agonism Increases Glucagon Secretion During Insulin-Induced Hypoglycemia.

Li NX, Brown S, Kowalski T, Wu M, Yang L, Dai G, Petrov A, Ding Y, Dlugos T, Wood HB, Wang L, Erion M, Sherwin R, Kelley DE.

Diabetes. 2018 Jul;67(7):1401-1413. doi: 10.2337/db18-0031. Epub 2018 Apr 18.

12.

Native Oxyntomodulin Has Significant Glucoregulatory Effects Independent of Weight Loss in Obese Humans With and Without Type 2 Diabetes.

Shankar SS, Shankar RR, Mixson LA, Miller DL, Pramanik B, O'Dowd AK, Williams DM, Frederick CB, Beals CR, Stoch SA, Steinberg HO, Kelley DE.

Diabetes. 2018 Jun;67(6):1105-1112. doi: 10.2337/db17-1331. Epub 2018 Mar 15.

13.

Superior Glycemic Control With a Glucose-Responsive Insulin Analog: Hepatic and Nonhepatic Impacts.

Moore MC, Kelley DE, Camacho RC, Zafian P, Ye T, Lin S, Kaarsholm NC, Nargund R, Kelly TM, Van Heek M, Previs SF, Moyes C, Smith MS, Farmer B, Williams P, Cherrington AD.

Diabetes. 2018 Jun;67(6):1173-1181. doi: 10.2337/db18-0099. Epub 2018 Mar 14.

14.

Quantifying ceramide kinetics in vivo using stable isotope tracers and LC-MS/MS.

Chen Y, Berejnaia O, Liu J, Wang SP, Daurio NA, Yin W, Mayoral R, Petrov A, Kasumov T, Zhang GF, Previs SF, Kelley DE, McLaren DG.

Am J Physiol Endocrinol Metab. 2018 Sep 1;315(3):E416-E424. doi: 10.1152/ajpendo.00457.2017. Epub 2018 Mar 6.

15.

Erratum. Engineering Glucose Responsiveness Into Insulin. Diabetes 2018;67:299-308.

Kaarsholm NC, Lin S, Yan L, Kelly T, van Heek M, Mu J, Wu M, Dai G, Cui Y, Zhu Y, Carballo-Jane E, Reddy V, Zafian P, Huo P, Shi S, Antochshuk V, Ogawa A, Liu F, Souza SC, Seghezzi W, Duffy JL, Erion M, Nargund RP, Kelley DE.

Diabetes. 2018 May;67(5):1030. doi: 10.2337/db18-er05a. Epub 2018 Feb 27. No abstract available.

16.

Prospective evaluation of insulin and incretin dynamics in obese adults with and without diabetes for 2 years after Roux-en-Y gastric bypass.

Purnell JQ, Johnson GS, Wahed AS, Dalla Man C, Piccinini F, Cobelli C, Prigeon RL, Goodpaster BH, Kelley DE, Staten MA, Foster-Schubert KE, Cummings DE, Flum DR, Courcoulas AP, Havel PJ, Wolfe BM.

Diabetologia. 2018 May;61(5):1142-1154. doi: 10.1007/s00125-018-4553-y. Epub 2018 Feb 10.

17.

Using [2H]water to quantify the contribution of de novo palmitate synthesis in plasma: enabling back-to-back studies.

Previs SF, Herath K, Nawrocki AR, Rodriguez CG, Slipetz D, Singh SB, Kang L, Bhat G, Roddy TP, Conarello S, Terebetski J, Erion MD, Kelley DE.

Am J Physiol Endocrinol Metab. 2018 Jul 1;315(1):E63-E71. doi: 10.1152/ajpendo.00010.2017. Epub 2018 Jan 2.

18.

A glucose-responsive insulin therapy protects animals against hypoglycemia.

Yang R, Wu M, Lin S, Nargund RP, Li X, Kelly T, Yan L, Dai G, Qian Y, Dallas-Yang Q, Fischer PA, Cui Y, Shen X, Huo P, Feng DD, Erion MD, Kelley DE, Mu J.

JCI Insight. 2018 Jan 11;3(1). pii: 97476. doi: 10.1172/jci.insight.97476. eCollection 2018 Jan 11.

19.

Insulin secretory effect of sitagliptin: assessment with a hyperglycemic clamp combined with a meal challenge.

Shankar SS, Shankar RR, Mixson LA, Miller DL, Steinberg HO, Beals CR, Kelley DE.

Am J Physiol Endocrinol Metab. 2018 Apr 1;314(4):E406-E412. doi: 10.1152/ajpendo.00238.2017. Epub 2017 Nov 14.

20.

Engineering Glucose Responsiveness Into Insulin.

Kaarsholm NC, Lin S, Yan L, Kelly T, van Heek M, Mu J, Wu M, Dai G, Cui Y, Zhu Y, Carballo-Jane E, Reddy V, Zafian P, Huo P, Shi S, Antochshuk V, Ogawa A, Liu F, Souza SC, Seghezzi W, Duffy JL, Erion M, Nargund RP, Kelley DE.

Diabetes. 2018 Feb;67(2):299-308. doi: 10.2337/db17-0577. Epub 2017 Nov 2. Erratum in: Diabetes. 2018 Feb 27;:.

21.

An integrin antagonist (MK-0429) decreases proteinuria and renal fibrosis in the ZSF1 rat diabetic nephropathy model.

Zhou X, Zhang J, Haimbach R, Zhu W, Mayer-Ezell R, Garcia-Calvo M, Smith E, Price O, Kan Y, Zycband E, Zhu Y, Hoek M, Cox JM, Ma L, Kelley DE, Pinto S.

Pharmacol Res Perspect. 2017 Oct;5(5). doi: 10.1002/prp2.354.

22.

Perceived support from a caregiver's social ties predicts subsequent care-recipient health.

Kelley DE, Lewis MA, Southwell BG.

Prev Med Rep. 2017 Aug 9;8:108-111. doi: 10.1016/j.pmedr.2017.08.001. eCollection 2017 Dec.

23.

Identifying principles for effective messages about chemicals in cigarette smoke.

Noar SM, Kelley DE, Boynton MH, Morgan JC, Hall MG, Mendel JR, Ribisl KM, Brewer NT.

Prev Med. 2018 Jan;106:31-37. doi: 10.1016/j.ypmed.2017.09.005. Epub 2017 Sep 8.

24.

Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation.

Kim CW, Addy C, Kusunoki J, Anderson NN, Deja S, Fu X, Burgess SC, Li C, Ruddy M, Chakravarthy M, Previs S, Milstein S, Fitzgerald K, Kelley DE, Horton JD.

Cell Metab. 2017 Sep 5;26(3):576. doi: 10.1016/j.cmet.2017.08.011. No abstract available.

25.

Reply to Letter to the Editor: "The art of quantifying glucose metabolism".

Wang SP, Satapati S, Daurio NA, Kelley DE, Previs SF.

Am J Physiol Endocrinol Metab. 2017 Aug 1;313(2):E259-E261. doi: 10.1152/ajpendo.00121.2017. No abstract available.

26.

Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation.

Kim CW, Addy C, Kusunoki J, Anderson NN, Deja S, Fu X, Burgess SC, Li C, Ruddy M, Chakravarthy M, Previs S, Milstein S, Fitzgerald K, Kelley DE, Horton JD.

Cell Metab. 2017 Aug 1;26(2):394-406.e6. doi: 10.1016/j.cmet.2017.07.009. Erratum in: Cell Metab. 2017 Sep 5;26(3):576.

27.

Enhancing Studies of Pharmacodynamic Mechanisms via Measurements of Metabolic Flux: Fundamental Concepts and Guiding Principles for Using Stable Isotope Tracers.

Daurio NA, Wang SP, Chen Y, Zhou H, McLaren DG, Roddy TP, Johns DG, Milot D, Kasumov T, Erion MD, Kelley DE, Previs SF.

J Pharmacol Exp Ther. 2017 Oct;363(1):80-91. doi: 10.1124/jpet.117.241091. Epub 2017 Jul 19. Review.

PMID:
28724692
28.

Systemic pan-AMPK activator MK-8722 improves glucose homeostasis but induces cardiac hypertrophy.

Myers RW, Guan HP, Ehrhart J, Petrov A, Prahalada S, Tozzo E, Yang X, Kurtz MM, Trujillo M, Gonzalez Trotter D, Feng D, Xu S, Eiermann G, Holahan MA, Rubins D, Conarello S, Niu X, Souza SC, Miller C, Liu J, Lu K, Feng W, Li Y, Painter RE, Milligan JA, He H, Liu F, Ogawa A, Wisniewski D, Rohm RJ, Wang L, Bunzel M, Qian Y, Zhu W, Wang H, Bennet B, LaFranco Scheuch L, Fernandez GE, Li C, Klimas M, Zhou G, van Heek M, Biftu T, Weber A, Kelley DE, Thornberry N, Erion MD, Kemp DM, Sebhat IK.

Science. 2017 Aug 4;357(6350):507-511. doi: 10.1126/science.aah5582. Epub 2017 Jul 13.

PMID:
28705990
29.

GPR120 suppresses adipose tissue lipolysis and synergizes with GPR40 in antidiabetic efficacy.

Satapati S, Qian Y, Wu MS, Petrov A, Dai G, Wang SP, Zhu Y, Shen X, Muise ES, Chen Y, Zycband E, Weinglass A, Di Salvo J, Debenham JS, Cox JM, Lan P, Shah V, Previs SF, Erion M, Kelley DE, Wang L, Howard AD, Shang J.

J Lipid Res. 2017 Aug;58(8):1561-1578. doi: 10.1194/jlr.M075044. Epub 2017 Jun 5.

30.

Effective Message Elements for Disclosures About Chemicals in Cigarette Smoke.

Kelley DE, Boynton MH, Noar SM, Morgan JC, Mendel JR, Ribisl KM, Stepanov I, Nylander-French LA, Brewer NT.

Nicotine Tob Res. 2018 Aug 14;20(9):1047-1054. doi: 10.1093/ntr/ntx109.

31.

Metabolic improvements following Roux-en-Y surgery assessed by solid meal test in subjects with short duration type 2 diabetes.

Shankar SS, Mixson LA, Chakravarthy M, Chisholm R, Acton AJ, Jones R, Mattar SG, Miller DL, Petry L, Beals CR, Stoch SA, Kelley DE, Considine RV.

BMC Obes. 2017 Mar 1;4:10. doi: 10.1186/s40608-017-0149-1. eCollection 2017.

32.

Using Doppler ultrasonography on day 34 of pregnancy to predict pregnancy loss in lactating dairy cattle.

Kelley DE, Galvão KN, Mortensen CJ, Risco CA, Ealy AD.

J Dairy Sci. 2017 Apr;100(4):3266-3271. doi: 10.3168/jds.2016-11955. Epub 2017 Feb 8.

33.

Phenotyping of adipose, liver, and skeletal muscle insulin resistance and response to pioglitazone in spontaneously obese rhesus monkeys.

Shang J, Previs SF, Conarello S, Chng K, Zhu Y, Souza SC, Staup M, Chen Y, Xie D, Zycband E, Schlessinger K, Johnson VP, Arreaza G, Liu F, Levitan D, Wang L, van Heek M, Erion M, Wang Y, Kelley DE.

Am J Physiol Endocrinol Metab. 2017 Apr 1;312(4):E235-E243. doi: 10.1152/ajpendo.00398.2016. Epub 2017 Jan 31.

34.

Correction: The Fatty Acid Synthase Inhibitor Platensimycin Improves Insulin Resistance without Inducing Liver Steatosis in Mice and Monkeys.

Singh SB, Kang L, Nawrocki AR, Zhou D, Wu M, Previs S, Miller C, Liu H, Hines CD, Madeira M, Cao J, Herath K, Spears LD, Semenkovich CF, Wang L, Kelley DE, Li C, Guan HP.

PLoS One. 2017 Jan 19;12(1):e0170721. doi: 10.1371/journal.pone.0170721. eCollection 2017.

35.

Changes in skeletal muscle and organ size after a weight-loss intervention in overweight and obese type 2 diabetic patients.

Gallagher D, Kelley DE, Thornton J, Boxt L, Pi-Sunyer X, Lipkin E, Nyenwe E, Janumala I, Heshka S; MRI Ancillary Study Group of the Look AHEAD Research Group.

Am J Clin Nutr. 2017 Jan;105(1):78-84. doi: 10.3945/ajcn.116.139188. Epub 2016 Nov 23.

36.

The Fatty Acid Synthase Inhibitor Platensimycin Improves Insulin Resistance without Inducing Liver Steatosis in Mice and Monkeys.

Singh SB, Kang L, Nawrocki AR, Zhou D, Wu M, Previs S, Miller C, Liu H, Hines CD, Madeira M, Cao J, Herath K, Spears LD, Semenkovich CF, Wang L, Kelley DE, Li C, Guan HP.

PLoS One. 2016 Oct 3;11(10):e0164133. doi: 10.1371/journal.pone.0164133. eCollection 2016. Erratum in: PLoS One. 2017 Jan 19;12 (1):e0170721. Spears, Larry D [added]; Semenkovich, Clay F [added].

37.

Quantifying rates of glucose production in vivo following an intraperitoneal tracer bolus.

Wang SP, Zhou D, Yao Z, Satapati S, Chen Y, Daurio NA, Petrov A, Shen X, Metzger D, Yin W, Nawrocki AR, Eiermann GJ, Hwa J, Fancourt C, Miller C, Herath K, Roddy TP, Slipetz D, Erion MD, Previs SF, Kelley DE.

Am J Physiol Endocrinol Metab. 2016 Dec 1;311(6):E911-E921. doi: 10.1152/ajpendo.00182.2016. Epub 2016 Sep 20.

38.

Physiological Expression of AMPKγ2RG Mutation Causes Wolff-Parkinson-White Syndrome and Induces Kidney Injury in Mice.

Yang X, Mudgett J, Bou-About G, Champy MF, Jacobs H, Monassier L, Pavlovic G, Sorg T, Herault Y, Petit-Demoulière B, Lu K, Feng W, Wang H, Ma LJ, Askew R, Erion MD, Kelley DE, Myers RW, Li C, Guan HP.

J Biol Chem. 2016 Nov 4;291(45):23428-23439. Epub 2016 Sep 12.

39.

Duodenal-jejunal bypass surgery induces hepatic lipidomic alterations associated with ameliorated hepatic steatosis in mice.

Shang J, Castro-Perez JM, Shen X, Zhu Y, Liu H, Qian Y, Previs S, Howard AD, Erion M, Kelley DE, Wang L.

Obesity (Silver Spring). 2016 Sep;24(9):1938-45. doi: 10.1002/oby.21583. Epub 2016 Jul 26.

40.

An Empirical Analysis of Indoor Tanners: Implications for Audience Segmentation in Campaigns.

Kelley DE, Noar SM, Myrick JG, Morales-Pico B, Zeitany A, Thomas NE.

J Health Commun. 2016 May;21(5):564-74. doi: 10.1080/10810730.2015.1114051. Epub 2016 Apr 26.

PMID:
27115046
41.

Linearity of β-cell response across the metabolic spectrum and to pharmacology: insights from a graded glucose infusion-based investigation series.

Shankar SS, Shankar RR, Mixson LA, Miller DL, Chung C, Cilissen C, Beals CR, Stoch SA, Steinberg HO, Kelley DE.

Am J Physiol Endocrinol Metab. 2016 Jun 1;310(11):E865-73. doi: 10.1152/ajpendo.00527.2015. Epub 2016 Apr 12.

42.

Early Clinical Detection of Pharmacologic Response in Insulin Action in a Nondiabetic Insulin-Resistant Population.

Shankar SS, Shankar RR, Railkar RA, Beals CR, Steinberg HO, Kelley DE.

Curr Ther Res Clin Exp. 2015 Aug 14;77:83-9. doi: 10.1016/j.curtheres.2015.08.001. eCollection 2015 Dec.

43.

Combined use of progesterone inserts, ultrasongraphy, and GnRH to identify and resynchronize nonpregnant cows and heifers 21 days after timed artificial insemination.

Kelley DE, Ibarbia L, Daetz R, Bittar JH, Risco CA, Santos JE, Ribeiro ES, Galvão KN.

Theriogenology. 2016 Jan 15;85(2):230-7. doi: 10.1016/j.theriogenology.2015.09.052. Epub 2015 Oct 8.

PMID:
26522703
44.

Glucagon receptor antagonism induces increased cholesterol absorption.

Guan HP, Yang X, Lu K, Wang SP, Castro-Perez JM, Previs S, Wright M, Shah V, Herath K, Xie D, Szeto D, Forrest G, Xiao JC, Palyha O, Sun LP, Andryuk PJ, Engel SS, Xiong Y, Lin S, Kelley DE, Erion MD, Davis HR, Wang L.

J Lipid Res. 2015 Nov;56(11):2183-95. doi: 10.1194/jlr.M060897. Epub 2015 Sep 15.

45.

Improved differentiation between knees with cartilage lesions and controls using 7T relaxation time mapping.

Wyatt C, Guha A, Venkatachari A, Li X, Krug R, Kelley DE, Link T, Majumdar S.

J Orthop Translat. 2015 Sep 15;3(4):197-204. doi: 10.1016/j.jot.2015.05.003. eCollection 2015 Oct.

46.

Tracer-based assessments of hepatic anaplerotic and TCA cycle flux: practicality, stoichiometry, and hidden assumptions.

Previs SF, Kelley DE.

Am J Physiol Endocrinol Metab. 2015 Oct 15;309(8):E727-35. doi: 10.1152/ajpendo.00216.2015. Epub 2015 Sep 1.

47.

Stewing in Not-So-Good Juices: Interactions of Skeletal Muscle With Adipose Secretions.

Kelley DE, Goodpaster BH.

Diabetes. 2015 Sep;64(9):3055-7. doi: 10.2337/db15-0403. No abstract available.

48.

L-Arginine supplementation 0.5% of diet during the last 90 days of gestation and 14 days postpartum reduced uterine fluid accumulation in the broodmare.

Mesa AM, Warren LK, Sheehan JM, Kelley DE, Mortensen CJ.

Anim Reprod Sci. 2015 Aug;159:46-51. doi: 10.1016/j.anireprosci.2015.05.011. Epub 2015 May 16.

PMID:
26036908
49.

Tracer-based estimates of protein flux in cases of incomplete product renewal: evidence and implications of heterogeneity in collagen turnover.

Zhou H, Wang SP, Herath K, Kasumov T, Sadygov RG, Previs SF, Kelley DE.

Am J Physiol Endocrinol Metab. 2015 Jul 15;309(2):E115-21. doi: 10.1152/ajpendo.00435.2014. Epub 2015 May 26.

50.

Acute hemodynamic and renal effects of glucagon-like peptide 1 analog and dipeptidyl peptidase-4 inhibitor in rats.

Zhou X, Huang CH, Lao J, Pocai A, Forrest G, Price O, Roy S, Kelley DE, Sullivan KA, Forrest MJ.

Cardiovasc Diabetol. 2015 Mar 7;14:29. doi: 10.1186/s12933-015-0194-3.

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