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Items: 10

1.

PET-guided treatment in patients with advanced-stage Hodgkin's lymphoma (HD18): final results of an open-label, international, randomised phase 3 trial by the German Hodgkin Study Group.

Borchmann P, Goergen H, Kobe C, Lohri A, Greil R, Eichenauer DA, Zijlstra JM, Markova J, Meissner J, Feuring-Buske M, Hüttmann A, Dierlamm J, Soekler M, Beck HJ, Willenbacher W, Ludwig WD, Pabst T, Topp MS, Hitz F, Bentz M, Keller UB, Kühnhardt D, Ostermann H, Schmitz N, Hertenstein B, Aulitzky W, Maschmeyer G, Vieler T, Eich H, Baues C, Stein H, Fuchs M, Kuhnert G, Diehl V, Dietlein M, Engert A.

Lancet. 2018 Dec 23;390(10114):2790-2802. doi: 10.1016/S0140-6736(17)32134-7. Epub 2017 Oct 20.

PMID:
29061295
2.

Lymphomagenic CARD11/BCL10/MALT1 signaling drives malignant B-cell proliferation via cooperative NF-κB and JNK activation.

Knies N, Alankus B, Weilemann A, Tzankov A, Brunner K, Ruff T, Kremer M, Keller UB, Lenz G, Ruland J.

Proc Natl Acad Sci U S A. 2015 Dec 29;112(52):E7230-8. doi: 10.1073/pnas.1507459112. Epub 2015 Dec 14.

3.

BET and HDAC inhibitors induce similar genes and biological effects and synergize to kill in Myc-induced murine lymphoma.

Bhadury J, Nilsson LM, Muralidharan SV, Green LC, Li Z, Gesner EM, Hansen HC, Keller UB, McLure KG, Nilsson JA.

Proc Natl Acad Sci U S A. 2014 Jul 1;111(26):E2721-30. doi: 10.1073/pnas.1406722111. Epub 2014 Jun 16.

4.

Stromal pleiotrophin regulates repopulation behavior of hematopoietic stem cells.

Istvanffy R, Kröger M, Eckl C, Gitzelmann S, Vilne B, Bock F, Graf S, Schiemann M, Keller UB, Peschel C, Oostendorp RA.

Blood. 2011 Sep 8;118(10):2712-22. doi: 10.1182/blood-2010-05-287235. Epub 2011 Jul 25.

5.

Skp2 directs Myc-mediated suppression of p27Kip1 yet has modest effects on Myc-driven lymphomagenesis.

Old JB, Kratzat S, Hoellein A, Graf S, Nilsson JA, Nilsson L, Nakayama KI, Peschel C, Cleveland JL, Keller UB.

Mol Cancer Res. 2010 Mar;8(3):353-62. doi: 10.1158/1541-7786.MCR-09-0232. Epub 2010 Mar 2.

6.

Myc targets Cks1 to provoke the suppression of p27Kip1, proliferation and lymphomagenesis.

Keller UB, Old JB, Dorsey FC, Nilsson JA, Nilsson L, MacLean KH, Chung L, Yang C, Spruck C, Boyd K, Reed SI, Cleveland JL.

EMBO J. 2007 May 16;26(10):2562-74. Epub 2007 Apr 26.

7.

Ink4c is dispensable for tumor suppression in Myc-induced B-cell lymphomagenesis.

Nilsson LM, Keller UB, Yang C, Nilsson JA, Cleveland JL, Roussel MF.

Oncogene. 2007 May 3;26(20):2833-9. Epub 2006 Nov 13.

PMID:
17099725
8.

Targeting ornithine decarboxylase in Myc-induced lymphomagenesis prevents tumor formation.

Nilsson JA, Keller UB, Baudino TA, Yang C, Norton S, Old JA, Nilsson LM, Neale G, Kramer DL, Porter CW, Cleveland JL.

Cancer Cell. 2005 May;7(5):433-44.

9.

Mnt loss triggers Myc transcription targets, proliferation, apoptosis, and transformation.

Nilsson JA, Maclean KH, Keller UB, Pendeville H, Baudino TA, Cleveland JL.

Mol Cell Biol. 2004 Feb;24(4):1560-9.

10.

c-Myc augments gamma irradiation-induced apoptosis by suppressing Bcl-XL.

Maclean KH, Keller UB, Rodriguez-Galindo C, Nilsson JA, Cleveland JL.

Mol Cell Biol. 2003 Oct;23(20):7256-70.

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