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Items: 1 to 50 of 124

1.

The prevalence and significance of radiographic incidental findings during initial staging of melanoma: a retrospective study.

Stump M, Keller JR, Mott SL, Stolmeier DA, Milhem MM, Liu V.

J Eur Acad Dermatol Venereol. 2019 Aug 30. doi: 10.1111/jdv.15912. [Epub ahead of print] No abstract available.

PMID:
31469463
2.

Id1 Ablation Protects Hematopoietic Stem Cells from Stress-Induced Exhaustion and Aging.

Singh SK, Singh S, Gadomski S, Sun L, Pfannenstein A, Magidson V, Chen X, Kozlov S, Tessarollo L, Klarmann KD, Keller JR.

Cell Stem Cell. 2018 Aug 2;23(2):252-265.e8. doi: 10.1016/j.stem.2018.06.001. Epub 2018 Jun 28.

3.

POGZ Is Required for Silencing Mouse Embryonic β-like Hemoglobin and Human Fetal Hemoglobin Expression.

Gudmundsdottir B, Gudmundsson KO, Klarmann KD, Singh SK, Sun L, Singh S, Du Y, Coppola V, Stockwin L, Nguyen N, Tessarollo L, Thorsteinsson L, Sigurjonsson OE, Gudmundsson S, Rafnar T, Tisdale JF, Keller JR.

Cell Rep. 2018 Jun 12;23(11):3236-3248. doi: 10.1016/j.celrep.2018.05.043.

4.

Therapeutic Plasma Exchange Use in Pediatric Neurologic Disorders at a Tertiary Care Center: A 10-Year Review.

Agarwal S, Keller JR, Nunneley CE, Muscal E, Braun MC, Srivaths P, Lotze TE.

J Child Neurol. 2018 Feb;33(2):140-145. doi: 10.1177/0883073817749368.

PMID:
29334853
5.

Eradication of Tumors through Simultaneous Ablation of CD276/B7-H3-Positive Tumor Cells and Tumor Vasculature.

Seaman S, Zhu Z, Saha S, Zhang XM, Yang MY, Hilton MB, Morris K, Szot C, Morris H, Swing DA, Tessarollo L, Smith SW, Degrado S, Borkin D, Jain N, Scheiermann J, Feng Y, Wang Y, Li J, Welsch D, DeCrescenzo G, Chaudhary A, Zudaire E, Klarmann KD, Keller JR, Dimitrov DS, St Croix B.

Cancer Cell. 2017 Apr 10;31(4):501-515.e8. doi: 10.1016/j.ccell.2017.03.005.

6.

RB inactivation in keratin 18 positive thymic epithelial cells promotes non-cell autonomous T cell hyperproliferation in genetically engineered mice.

Song Y, Sullivan T, Klarmann K, Gilbert D, O'Sullivan TN, Lu L, Wang S, Haines DC, Van Dyke T, Keller JR.

PLoS One. 2017 Feb 3;12(2):e0171510. doi: 10.1371/journal.pone.0171510. eCollection 2017.

7.

RanBPM (RanBP9) regulates mouse c-Kit receptor level and is essential for normal development of bone marrow progenitor cells.

Puverel S, Kiris E, Singh S, Klarmann KD, Coppola V, Keller JR, Tessarollo L.

Oncotarget. 2016 Dec 20;7(51):85109-85123. doi: 10.18632/oncotarget.13198.

8.

TET2 binds the androgen receptor and loss is associated with prostate cancer.

Nickerson ML, Das S, Im KM, Turan S, Berndt SI, Li H, Lou H, Brodie SA, Billaud JN, Zhang T, Bouk AJ, Butcher D, Wang Z, Sun L, Misner K, Tan W, Esnakula A, Esposito D, Huang WY, Hoover RN, Tucker MA, Keller JR, Boland J, Brown K, Anderson SK, Moore LE, Isaacs WB, Chanock SJ, Yeager M, Dean M, Andresson T.

Oncogene. 2017 Apr;36(15):2172-2183. doi: 10.1038/onc.2016.376. Epub 2016 Nov 7.

9.

Synthetic viability by BRCA2 and PARP1/ARTD1 deficiencies.

Ding X, Ray Chaudhuri A, Callen E, Pang Y, Biswas K, Klarmann KD, Martin BK, Burkett S, Cleveland L, Stauffer S, Sullivan T, Dewan A, Marks H, Tubbs AT, Wong N, Buehler E, Akagi K, Martin SE, Keller JR, Nussenzweig A, Sharan SK.

Nat Commun. 2016 Aug 8;7:12425. doi: 10.1038/ncomms12425.

10.

Loss of Folliculin Disrupts Hematopoietic Stem Cell Quiescence and Homeostasis Resulting in Bone Marrow Failure.

Baba M, Toyama H, Sun L, Takubo K, Suh HC, Hasumi H, Nakamura-Ishizu A, Hasumi Y, Klarmann KD, Nakagata N, Schmidt LS, Linehan WM, Suda T, Keller JR.

Stem Cells. 2016 Apr;34(4):1068-82. doi: 10.1002/stem.2293. Epub 2016 Feb 2.

11.

Vav1 Regulates Mesenchymal Stem Cell Differentiation Decision Between Adipocyte and Chondrocyte via Sirt1.

Qu P, Wang L, Min Y, McKennett L, Keller JR, Lin PC.

Stem Cells. 2016 Jul;34(7):1934-46. doi: 10.1002/stem.2365. Epub 2016 Apr 21.

12.

BRCA2 minor transcript lacking exons 4-7 supports viability in mice and may account for survival of humans with a pathogenic biallelic mutation.

Thirthagiri E, Klarmann KD, Shukla AK, Southon E, Biswas K, Martin BK, North SL, Magidson V, Burkett S, Haines DC, Noer K, Matthai R, Tessarollo L, Loncarek J, Keller JR, Sharan SK.

Hum Mol Genet. 2016 May 15;25(10):1934-1945. Epub 2016 Feb 26.

13.

Inhibitor of differentiation 1 transcription factor promotes metabolic reprogramming in hepatocellular carcinoma cells.

Sharma BK, Kolhe R, Black SM, Keller JR, Mivechi NF, Satyanarayana A.

FASEB J. 2016 Jan;30(1):262-75. doi: 10.1096/fj.15-277749. Epub 2015 Sep 1.

14.

IFN-γ causes aplastic anemia by altering hematopoietic stem/progenitor cell composition and disrupting lineage differentiation.

Lin FC, Karwan M, Saleh B, Hodge DL, Chan T, Boelte KC, Keller JR, Young HA.

Blood. 2014 Dec 11;124(25):3699-708. doi: 10.1182/blood-2014-01-549527. Epub 2014 Oct 23.

15.

Gfi-1 regulates the erythroid transcription factor network through Id2 repression in murine hematopoietic progenitor cells.

Kim W, Klarmann KD, Keller JR.

Blood. 2014 Sep 4;124(10):1586-96. doi: 10.1182/blood-2014-02-556522. Epub 2014 Jul 22. Erratum in: Blood. 2016 Mar 17;127(11):1517. Blood. 2016 Mar 17;127(11):1517.

16.

Stemness of T cells and the hematopoietic stem cells: fate, memory, niche, cytokines.

Aiello FB, Graciotti L, Procopio AD, Keller JR, Durum SK.

Cytokine Growth Factor Rev. 2013 Dec;24(6):485-501. doi: 10.1016/j.cytogfr.2013.10.002. Epub 2013 Oct 27. Review.

17.

C/EBPγ suppresses senescence and inflammatory gene expression by heterodimerizing with C/EBPβ.

Huggins CJ, Malik R, Lee S, Salotti J, Thomas S, Martin N, Quiñones OA, Alvord WG, Olanich ME, Keller JR, Johnson PF.

Mol Cell Biol. 2013 Aug;33(16):3242-58. doi: 10.1128/MCB.01674-12. Epub 2013 Jun 17.

18.

Sirt1 ablation promotes stress-induced loss of epigenetic and genomic hematopoietic stem and progenitor cell maintenance.

Singh SK, Williams CA, Klarmann K, Burkett SS, Keller JR, Oberdoerffer P.

J Exp Med. 2013 May 6;210(5):987-1001. doi: 10.1084/jem.20121608. Epub 2013 Apr 29.

19.

Epigenetic regulation of SOX9 by the NF-κB signaling pathway in pancreatic cancer stem cells.

Sun L, Mathews LA, Cabarcas SM, Zhang X, Yang A, Zhang Y, Young MR, Klarmann KD, Keller JR, Farrar WL.

Stem Cells. 2013 Aug;31(8):1454-66. doi: 10.1002/stem.1394.

20.

FBXW7α attenuates inflammatory signalling by downregulating C/EBPδ and its target gene Tlr4.

Balamurugan K, Sharan S, Klarmann KD, Zhang Y, Coppola V, Summers GH, Roger T, Morrison DK, Keller JR, Sterneck E.

Nat Commun. 2013;4:1662. doi: 10.1038/ncomms2677.

21.

The folliculin-FNIP1 pathway deleted in human Birt-Hogg-Dubé syndrome is required for murine B-cell development.

Baba M, Keller JR, Sun HW, Resch W, Kuchen S, Suh HC, Hasumi H, Hasumi Y, Kieffer-Kwon KR, Gonzalez CG, Hughes RM, Klein ME, Oh HF, Bible P, Southon E, Tessarollo L, Schmidt LS, Linehan WM, Casellas R.

Blood. 2012 Aug 9;120(6):1254-61. doi: 10.1182/blood-2012-02-410407. Epub 2012 Jun 18.

22.

Transplantation of mouse fetal liver cells for analyzing the function of hematopoietic stem and progenitor cells.

Gudmundsson KO, Stull SW, Keller JR.

Methods Mol Biol. 2012;879:123-33. doi: 10.1007/978-1-61779-815-3_8.

23.
24.

RapGEF2 is essential for embryonic hematopoiesis but dispensable for adult hematopoiesis.

Satyanarayana A, Gudmundsson KO, Chen X, Coppola V, Tessarollo L, Keller JR, Hou SX.

Blood. 2010 Oct 21;116(16):2921-31. doi: 10.1182/blood-2010-01-262964. Epub 2010 Jul 1.

25.

Repression of Id2 expression by Gfi-1 is required for B-cell and myeloid development.

Li H, Ji M, Klarmann KD, Keller JR.

Blood. 2010 Aug 19;116(7):1060-9. doi: 10.1182/blood-2009-11-255075. Epub 2010 May 7.

26.

Cell-nonautonomous function of Id1 in the hematopoietic progenitor cell niche.

Suh HC, Ji M, Gooya J, Lee M, Klarmann KD, Keller JR.

Blood. 2009 Aug 6;114(6):1186-95. doi: 10.1182/blood-2008-09-179788. Epub 2009 May 28.

27.

The lamin B receptor under transcriptional control of C/EBPepsilon is required for morphological but not functional maturation of neutrophils.

Cohen TV, Klarmann KD, Sakchaisri K, Cooper JP, Kuhns D, Anver M, Johnson PF, Williams SC, Keller JR, Stewart CL.

Hum Mol Genet. 2008 Oct 1;17(19):2921-33. doi: 10.1093/hmg/ddn191. Epub 2008 Jul 11.

28.

Id1 immortalizes hematopoietic progenitors in vitro and promotes a myeloproliferative disease in vivo.

Suh HC, Leeanansaksiri W, Ji M, Klarmann KD, Renn K, Gooya J, Smith D, McNiece I, Lugthart S, Valk PJ, Delwel R, Keller JR.

Oncogene. 2008 Sep 18;27(42):5612-23. doi: 10.1038/onc.2008.175. Epub 2008 Jun 9.

29.

Id2 intrinsically regulates lymphoid and erythroid development via interaction with different target proteins.

Ji M, Li H, Suh HC, Klarmann KD, Yokota Y, Keller JR.

Blood. 2008 Aug 15;112(4):1068-77. doi: 10.1182/blood-2008-01-133504. Epub 2008 Jun 3.

30.

DNA hypomethylation caused by Lsh deletion promotes erythroleukemia development.

Fan T, Schmidtmann A, Xi S, Briones V, Zhu H, Suh HC, Gooya J, Keller JR, Xu H, Roayaei J, Anver M, Ruscetti S, Muegge K.

Epigenetics. 2008 May-Jun;3(3):134-42. Epub 2008 May 9.

31.

The role of p202 in regulating hematopoietic cell proliferation and differentiation.

Ludlow LE, Purton LE, Klarmann K, Gough DJ, Hii LL, Trapani JA, Keller JR, Clarke CJ, Johnstone RW.

J Interferon Cytokine Res. 2008 Jan;28(1):5-11. doi: 10.1089/jir.2007.0070.

PMID:
18370867
32.

Gene expression analysis of hematopoietic progenitor cells identifies Dlg7 as a potential stem cell gene.

Gudmundsson KO, Thorsteinsson L, Sigurjonsson OE, Keller JR, Olafsson K, Egeland T, Gudmundsson S, Rafnar T.

Stem Cells. 2007 Jun;25(6):1498-506. Epub 2007 Feb 22.

33.

IL-7 induces myelopoiesis and erythropoiesis.

Aiello FB, Keller JR, Klarmann KD, Dranoff G, Mazzucchelli R, Durum SK.

J Immunol. 2007 Feb 1;178(3):1553-63.

34.

Role of the intracellular domain of IL-7 receptor in T cell development.

Jiang Q, Huang J, Li WQ, Cavinato T, Keller JR, Durum SK.

J Immunol. 2007 Jan 1;178(1):228-34.

35.

Novel lymphotoxin alpha (LTalpha) knockout mice with unperturbed tumor necrosis factor expression: reassessing LTalpha biological functions.

Liepinsh DJ, Grivennikov SI, Klarmann KD, Lagarkova MA, Drutskaya MS, Lockett SJ, Tessarollo L, McAuliffe M, Keller JR, Kuprash DV, Nedospasov SA.

Mol Cell Biol. 2006 Jun;26(11):4214-25.

36.

Combined loss of Cdk2 and Cdk4 results in embryonic lethality and Rb hypophosphorylation.

Berthet C, Klarmann KD, Hilton MB, Suh HC, Keller JR, Kiyokawa H, Kaldis P.

Dev Cell. 2006 May;10(5):563-73.

37.

C/EBPalpha determines hematopoietic cell fate in multipotential progenitor cells by inhibiting erythroid differentiation and inducing myeloid differentiation.

Suh HC, Gooya J, Renn K, Friedman AD, Johnson PF, Keller JR.

Blood. 2006 Jun 1;107(11):4308-16. Epub 2006 Feb 9.

38.

p205, a potential tumor suppressor, inhibits cell proliferation via multiple pathways of cell cycle regulation.

Asefa B, Dermott JM, Kaldis P, Stefanisko K, Garfinkel DJ, Keller JR.

FEBS Lett. 2006 Feb 20;580(5):1205-14. Epub 2006 Jan 20.

39.
40.

Retroviral transduction of IL-7Ralpha into IL-7Ralpha-/- bone marrow progenitors: correction of lymphoid deficiency and induction of neutrophilia.

Jiang Q, Li WQ, Aiello FB, Klarmann KD, Keller JR, Durum SK.

Gene Ther. 2005 Dec;12(24):1761-8.

PMID:
16208423
41.

IL-3 induces inhibitor of DNA-binding protein-1 in hemopoietic progenitor cells and promotes myeloid cell development.

Leeanansaksiri W, Wang H, Gooya JM, Renn K, Abshari M, Tsai S, Keller JR.

J Immunol. 2005 Jun 1;174(11):7014-21.

42.

Inhibition of growth by p205: a nuclear protein and putative tumor suppressor expressed during myeloid cell differentiation.

Dermott JM, Gooya JM, Asefa B, Weiler SR, Smith M, Keller JR.

Stem Cells. 2004;22(5):832-48.

43.

Distinct regions of the interleukin-7 receptor regulate different Bcl2 family members.

Jiang Q, Li WQ, Hofmeister RR, Young HA, Hodge DR, Keller JR, Khaled AR, Durum SK.

Mol Cell Biol. 2004 Jul;24(14):6501-13.

44.

Interleukin-7 inactivates the pro-apoptotic protein Bad promoting T cell survival.

Li WQ, Jiang Q, Khaled AR, Keller JR, Durum SK.

J Biol Chem. 2004 Jul 9;279(28):29160-6. Epub 2004 Apr 30.

45.

JAK2 contributes to the intrinsic capacity of primary hematopoietic cells to respond to stem cell factor.

Radosevic N, Winterstein D, Keller JR, Neubauer H, Pfeffer K, Linnekin D.

Exp Hematol. 2004 Feb;32(2):149-56.

PMID:
15102475
46.

The interferon-inducible p200 family of proteins: a perspective on their roles in cell cycle regulation and differentiation.

Asefa B, Klarmann KD, Copeland NG, Gilbert DJ, Jenkins NA, Keller JR.

Blood Cells Mol Dis. 2004 Jan-Feb;32(1):155-67. Review.

PMID:
14757431
47.

Identification of in vitro growth conditions for c-Kit-negative hematopoietic stem cells.

Klarmann K, Ortiz M, Davies M, Keller JR.

Blood. 2003 Nov 1;102(9):3120-8. Epub 2003 Jul 10.

PMID:
12855562
48.

Bcl11a is essential for normal lymphoid development.

Liu P, Keller JR, Ortiz M, Tessarollo L, Rachel RA, Nakamura T, Jenkins NA, Copeland NG.

Nat Immunol. 2003 Jun;4(6):525-32. Epub 2003 Apr 28.

PMID:
12717432
49.

In vivo retroviral gene transfer by direct intrafemoral injection results in correction of the SCID phenotype in Jak3 knock-out animals.

McCauslin CS, Wine J, Cheng L, Klarmann KD, Candotti F, Clausen PA, Spence SE, Keller JR.

Blood. 2003 Aug 1;102(3):843-8. Epub 2003 Apr 10.

PMID:
12689938
50.

Mapping gene expression patterns during myeloid differentiation using the EML hematopoietic progenitor cell line.

Du Y, Campbell JL, Nalbant D, Youn H, Bass AC, Cobos E, Tsai S, Keller JR, Williams SC.

Exp Hematol. 2002 Jul;30(7):649-58.

PMID:
12135661

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