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Items: 1 to 50 of 119

1.

The E3 ligase adaptor molecule SPOP regulates fetal hemoglobin levels in adult erythroid cells.

Lan X, Khandros E, Huang P, Peslak SA, Bhardwaj SK, Grevet JD, Abdulmalik O, Wang H, Keller CA, Giardine B, Baeza J, Duffner ER, El Demerdash O, Wu XS, Vakoc CR, Garcia BA, Hardison RC, Shi J, Blobel GA.

Blood Adv. 2019 May 28;3(10):1586-1597. doi: 10.1182/bloodadvances.2019032318.

2.

Interrogating Histone Acetylation and BRD4 as Mitotic Bookmarks of Transcription.

Behera V, Stonestrom AJ, Hamagami N, Hsiung CC, Keller CA, Giardine B, Sidoli S, Yuan ZF, Bhanu NV, Werner MT, Wang H, Garcia BA, Hardison RC, Blobel GA.

Cell Rep. 2019 Apr 9;27(2):400-415.e5. doi: 10.1016/j.celrep.2019.03.057.

3.

Transcriptional Burst Initiation and Polymerase Pause Release Are Key Control Points of Transcriptional Regulation.

Bartman CR, Hamagami N, Keller CA, Giardine B, Hardison RC, Blobel GA, Raj A.

Mol Cell. 2019 Feb 7;73(3):519-532.e4. doi: 10.1016/j.molcel.2018.11.004. Epub 2018 Dec 13.

PMID:
30554946
4.

Errors and improvements in the use of archived meteorological data for chemical transport modeling: an analysis using GEOS-Chem v11-01 driven by GEOS-5 meteorology.

Yu K, Keller CA, Jacob DJ, Molod AM, Eastham SD, Long MS.

Geosci Model Dev. 2018;11(1):305-319. doi: 10.5194/gmd-11-305-2018. Epub 2018 Jan 23.

5.

Global Sources of Fine Particulate Matter: Interpretation of PM2.5 Chemical Composition Observed by SPARTAN using a Global Chemical Transport Model.

Weagle CL, Snider G, Li C, van Donkelaar A, Philip S, Bissonnette P, Burke J, Jackson J, Latimer R, Stone E, Abboud I, Akoshile C, Anh NX, Brook JR, Cohen A, Dong J, Gibson MD, Griffith D, He KB, Holben BN, Kahn R, Keller CA, Kim JS, Lagrosas N, Lestari P, Khian YL, Liu Y, Marais EA, Martins JV, Misra A, Muliane U, Pratiwi R, Quel EJ, Salam A, Segev L, Tripathi SN, Wang C, Zhang Q, Brauer M, Rudich Y, Martin RV.

Environ Sci Technol. 2018 Oct 16;52(20):11670-11681. doi: 10.1021/acs.est.8b01658. Epub 2018 Oct 1.

PMID:
30215246
6.

Domain-focused CRISPR screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells.

Grevet JD, Lan X, Hamagami N, Edwards CR, Sankaranarayanan L, Ji X, Bhardwaj SK, Face CJ, Posocco DF, Abdulmalik O, Keller CA, Giardine B, Sidoli S, Garcia BA, Chou ST, Liebhaber SA, Hardison RC, Shi J, Blobel GA.

Science. 2018 Jul 20;361(6399):285-290. doi: 10.1126/science.aao0932.

7.

In situ analysis of mTORC1/2 and cellular metabolism-related proteins in human Lymphangioleiomyomatosis.

Krencz I, Sebestyen A, Papay J, Jeney A, Hujber Z, Burger CD, Keller CA, Khoor A.

Hum Pathol. 2018 Sep;79:199-207. doi: 10.1016/j.humpath.2018.05.018. Epub 2018 Jun 6.

PMID:
29885404
8.

Diagnosis of Acute Cellular Rejection Using Probe-based Confocal Laser Endomicroscopy in Lung Transplant Recipients: A Prospective, Multicenter Trial.

Keller CA, Khoor A, Arenberg DA, Smith MA, Islam SU.

Transplantation. 2019 Feb;103(2):428-434. doi: 10.1097/TP.0000000000002306.

PMID:
29847505
9.

Establishment of regulatory elements during erythro-megakaryopoiesis identifies hematopoietic lineage-commitment points.

Heuston EF, Keller CA, Lichtenberg J, Giardine B, Anderson SM; NIH Intramural Sequencing Center, Hardison RC, Bodine DM.

Epigenetics Chromatin. 2018 May 28;11(1):22. doi: 10.1186/s13072-018-0195-z.

10.

Utilization and Cost Analysis of Lung Transplantation and Survival After 10 Years of Adapting the Lung Allocation Score.

Keller CA, Gonwa TA, White LJ, Rucci ME, Visscher SL, Kennedy CC, Daly RC, Naessens JM.

Transplantation. 2019 Mar;103(3):638-646. doi: 10.1097/TP.0000000000002227.

PMID:
29697575
11.

Exploiting genetic variation to uncover rules of transcription factor binding and chromatin accessibility.

Behera V, Evans P, Face CJ, Hamagami N, Sankaranarayanan L, Keller CA, Giardine B, Tan K, Hardison RC, Shi J, Blobel GA.

Nat Commun. 2018 Feb 22;9(1):782. doi: 10.1038/s41467-018-03082-6.

12.

Feasibility, Safety, and Tolerance of Mesenchymal Stem Cell Therapy for Obstructive Chronic Lung Allograft Dysfunction.

Keller CA, Gonwa TA, Hodge DO, Hei DJ, Centanni JM, Zubair AC.

Stem Cells Transl Med. 2018 Feb;7(2):161-167. doi: 10.1002/sctm.17-0198. Epub 2018 Jan 11.

13.

Comparative analysis of three-dimensional chromosomal architecture identifies a novel fetal hemoglobin regulatory element.

Huang P, Keller CA, Giardine B, Grevet JD, Davies JOJ, Hughes JR, Kurita R, Nakamura Y, Hardison RC, Blobel GA.

Genes Dev. 2017 Aug 15;31(16):1704-1713. doi: 10.1101/gad.303461.117. Epub 2017 Sep 15.

14.

The BET Protein BRD2 Cooperates with CTCF to Enforce Transcriptional and Architectural Boundaries.

Hsu SC, Gilgenast TG, Bartman CR, Edwards CR, Stonestrom AJ, Huang P, Emerson DJ, Evans P, Werner MT, Keller CA, Giardine B, Hardison RC, Raj A, Phillips-Cremins JE, Blobel GA.

Mol Cell. 2017 Apr 6;66(1):102-116.e7. doi: 10.1016/j.molcel.2017.02.027.

15.

Protective and Pathogenic Roles of CD8+ T Lymphocytes in Murine Orientia tsutsugamushi Infection.

Hauptmann M, Kolbaum J, Lilla S, Wozniak D, Gharaibeh M, Fleischer B, Keller CA.

PLoS Negl Trop Dis. 2016 Sep 8;10(9):e0004991. doi: 10.1371/journal.pntd.0004991. eCollection 2016 Sep.

16.

A hyperactive transcriptional state marks genome reactivation at the mitosis-G1 transition.

Hsiung CC, Bartman CR, Huang P, Ginart P, Stonestrom AJ, Keller CA, Face C, Jahn KS, Evans P, Sankaranarayanan L, Giardine B, Hardison RC, Raj A, Blobel GA.

Genes Dev. 2016 Jun 15;30(12):1423-39. doi: 10.1101/gad.280859.116.

17.

Giant cell interstitial pneumonia in patients without hard metal exposure: analysis of 3 cases and review of the literature.

Khoor A, Roden AC, Colby TV, Roggli VL, Elrefaei M, Alvarez F, Erasmus DB, Mallea JM, Murray DL, Keller CA.

Hum Pathol. 2016 Apr;50:176-82. doi: 10.1016/j.humpath.2015.12.004. Epub 2015 Dec 18. Review.

PMID:
26997453
18.

SBR-Blood: systems biology repository for hematopoietic cells.

Lichtenberg J, Heuston EF, Mishra T, Keller CA, Hardison RC, Bodine DM.

Nucleic Acids Res. 2016 Jan 4;44(D1):D925-31. doi: 10.1093/nar/gkv1263. Epub 2015 Nov 20.

19.

Genome-Wide Organization of GATA1 and TAL1 Determined at High Resolution.

Han GC, Vinayachandran V, Bataille AR, Park B, Chan-Salis KY, Keller CA, Long M, Mahony S, Hardison RC, Pugh BF.

Mol Cell Biol. 2015 Oct 26;36(1):157-72. doi: 10.1128/MCB.00806-15. Print 2016 Jan 1.

20.

Mayo clinic experience of lung transplantation in pulmonary lymphangioleiomyomatosis.

Ussavarungsi K, Hu X, Scott JP, Erasmus DB, Mallea JM, Alvarez F, Lee AS, Keller CA, Ryu JH, Burger CD.

Respir Med. 2015 Oct;109(10):1354-9. doi: 10.1016/j.rmed.2015.08.014. Epub 2015 Aug 24.

21.

Occupancy by key transcription factors is a more accurate predictor of enhancer activity than histone modifications or chromatin accessibility.

Dogan N, Wu W, Morrissey CS, Chen KB, Stonestrom A, Long M, Keller CA, Cheng Y, Jain D, Visel A, Pennacchio LA, Weiss MJ, Blobel GA, Hardison RC.

Epigenetics Chromatin. 2015 Apr 23;8:16. doi: 10.1186/s13072-015-0009-5. eCollection 2015.

22.

An overview of immunosuppression in solid organ transplantation.

Enderby C, Keller CA.

Am J Manag Care. 2015 Jan;21(1 Suppl):s12-23.

23.

Dynamics of GATA1 binding and expression response in a GATA1-induced erythroid differentiation system.

Jain D, Mishra T, Giardine BM, Keller CA, Morrissey CS, Magargee S, Dorman CM, Long M, Weiss MJ, Hardison RC.

Genom Data. 2015 Jun 1;4:1-7.

24.

Functions of BET proteins in erythroid gene expression.

Stonestrom AJ, Hsu SC, Jahn KS, Huang P, Keller CA, Giardine BM, Kadauke S, Campbell AE, Evans P, Hardison RC, Blobel GA.

Blood. 2015 Apr 30;125(18):2825-34. doi: 10.1182/blood-2014-10-607309. Epub 2015 Feb 18.

25.

Weight loss prior to lung transplantation is associated with improved survival.

Chandrashekaran S, Keller CA, Kremers WK, Peters SG, Hathcock MA, Kennedy CC.

J Heart Lung Transplant. 2015 May;34(5):651-7. doi: 10.1016/j.healun.2014.11.018. Epub 2014 Nov 17.

26.

Principles of regulatory information conservation between mouse and human.

Cheng Y, Ma Z, Kim BH, Wu W, Cayting P, Boyle AP, Sundaram V, Xing X, Dogan N, Li J, Euskirchen G, Lin S, Lin Y, Visel A, Kawli T, Yang X, Patacsil D, Keller CA, Giardine B; mouse ENCODE Consortium, Kundaje A, Wang T, Pennacchio LA, Weng Z, Hardison RC, Snyder MP.

Nature. 2014 Nov 20;515(7527):371-375. doi: 10.1038/nature13985.

27.

A comparative encyclopedia of DNA elements in the mouse genome.

Yue F, Cheng Y, Breschi A, Vierstra J, Wu W, Ryba T, Sandstrom R, Ma Z, Davis C, Pope BD, Shen Y, Pervouchine DD, Djebali S, Thurman RE, Kaul R, Rynes E, Kirilusha A, Marinov GK, Williams BA, Trout D, Amrhein H, Fisher-Aylor K, Antoshechkin I, DeSalvo G, See LH, Fastuca M, Drenkow J, Zaleski C, Dobin A, Prieto P, Lagarde J, Bussotti G, Tanzer A, Denas O, Li K, Bender MA, Zhang M, Byron R, Groudine MT, McCleary D, Pham L, Ye Z, Kuan S, Edsall L, Wu YC, Rasmussen MD, Bansal MS, Kellis M, Keller CA, Morrissey CS, Mishra T, Jain D, Dogan N, Harris RS, Cayting P, Kawli T, Boyle AP, Euskirchen G, Kundaje A, Lin S, Lin Y, Jansen C, Malladi VS, Cline MS, Erickson DT, Kirkup VM, Learned K, Sloan CA, Rosenbloom KR, Lacerda de Sousa B, Beal K, Pignatelli M, Flicek P, Lian J, Kahveci T, Lee D, Kent WJ, Ramalho Santos M, Herrero J, Notredame C, Johnson A, Vong S, Lee K, Bates D, Neri F, Diegel M, Canfield T, Sabo PJ, Wilken MS, Reh TA, Giste E, Shafer A, Kutyavin T, Haugen E, Dunn D, Reynolds AP, Neph S, Humbert R, Hansen RS, De Bruijn M, Selleri L, Rudensky A, Josefowicz S, Samstein R, Eichler EE, Orkin SH, Levasseur D, Papayannopoulou T, Chang KH, Skoultchi A, Gosh S, Disteche C, Treuting P, Wang Y, Weiss MJ, Blobel GA, Cao X, Zhong S, Wang T, Good PJ, Lowdon RF, Adams LB, Zhou XQ, Pazin MJ, Feingold EA, Wold B, Taylor J, Mortazavi A, Weissman SM, Stamatoyannopoulos JA, Snyder MP, Guigo R, Gingeras TR, Gilbert DM, Hardison RC, Beer MA, Ren B; Mouse ENCODE Consortium.

Nature. 2014 Nov 20;515(7527):355-64. doi: 10.1038/nature13992.

28.

Genome accessibility is widely preserved and locally modulated during mitosis.

Hsiung CC, Morrissey CS, Udugama M, Frank CL, Keller CA, Baek S, Giardine B, Crawford GE, Sung MH, Hardison RC, Blobel GA.

Genome Res. 2015 Feb;25(2):213-25. doi: 10.1101/gr.180646.114. Epub 2014 Nov 4.

29.

Divergent functions of hematopoietic transcription factors in lineage priming and differentiation during erythro-megakaryopoiesis.

Pimkin M, Kossenkov AV, Mishra T, Morrissey CS, Wu W, Keller CA, Blobel GA, Lee D, Beer MA, Hardison RC, Weiss MJ.

Genome Res. 2014 Dec;24(12):1932-44. doi: 10.1101/gr.164178.113. Epub 2014 Oct 15.

30.

Dynamic shifts in occupancy by TAL1 are guided by GATA factors and drive large-scale reprogramming of gene expression during hematopoiesis.

Wu W, Morrissey CS, Keller CA, Mishra T, Pimkin M, Blobel GA, Weiss MJ, Hardison RC.

Genome Res. 2014 Dec;24(12):1945-62. doi: 10.1101/gr.164830.113. Epub 2014 Oct 15.

31.

Inhaled nitric oxide as a potential rescue therapy for persistent hepatopulmonary syndrome after liver transplantation.

Karnatovskaia LV, Matharu J, Burger C, Keller CA.

Transplantation. 2014 Sep 27;98(6):e64-6. doi: 10.1097/TP.0000000000000364. No abstract available.

PMID:
25221906
32.

Dissemination of Orientia tsutsugamushi and inflammatory responses in a murine model of scrub typhus.

Keller CA, Hauptmann M, Kolbaum J, Gharaibeh M, Neumann M, Glatzel M, Fleischer B.

PLoS Negl Trop Dis. 2014 Aug 14;8(8):e3064. doi: 10.1371/journal.pntd.0003064. eCollection 2014 Aug.

33.

Tacrolimus dosage requirements in lung transplant recipients receiving antifungal prophylaxis with voriconazole followed by itraconazole: a preliminary prospective study.

Enderby CY, Heckman MG, Thomas CS, Keller CA.

Clin Transplant. 2014 Aug;28(8):911-5. doi: 10.1111/ctr.12403. Epub 2014 Jul 8.

PMID:
24931421
34.

Noninvasive assessment of right heart function and hemodynamics during exercise in patients with pulmonary arterial hypertension.

Freeman ML, Landolfo C, Safford RE, Keller CA, Heckman MG, Burger CD.

South Med J. 2013 Feb;106(2):141-6. doi: 10.1097/SMJ.0b013e3182805165.

35.

An encyclopedia of mouse DNA elements (Mouse ENCODE).

Mouse ENCODE Consortium, Stamatoyannopoulos JA, Snyder M, Hardison R, Ren B, Gingeras T, Gilbert DM, Groudine M, Bender M, Kaul R, Canfield T, Giste E, Johnson A, Zhang M, Balasundaram G, Byron R, Roach V, Sabo PJ, Sandstrom R, Stehling AS, Thurman RE, Weissman SM, Cayting P, Hariharan M, Lian J, Cheng Y, Landt SG, Ma Z, Wold BJ, Dekker J, Crawford GE, Keller CA, Wu W, Morrissey C, Kumar SA, Mishra T, Jain D, Byrska-Bishop M, Blankenberg D, Lajoie BR, Jain G, Sanyal A, Chen KB, Denas O, Taylor J, Blobel GA, Weiss MJ, Pimkin M, Deng W, Marinov GK, Williams BA, Fisher-Aylor KI, Desalvo G, Kiralusha A, Trout D, Amrhein H, Mortazavi A, Edsall L, McCleary D, Kuan S, Shen Y, Yue F, Ye Z, Davis CA, Zaleski C, Jha S, Xue C, Dobin A, Lin W, Fastuca M, Wang H, Guigo R, Djebali S, Lagarde J, Ryba T, Sasaki T, Malladi VS, Cline MS, Kirkup VM, Learned K, Rosenbloom KR, Kent WJ, Feingold EA, Good PJ, Pazin M, Lowdon RF, Adams LB.

Genome Biol. 2012 Aug 13;13(8):418. doi: 10.1186/gb-2012-13-8-418.

36.

Traumatic bronchial rupture and platypnea-orthodeoxia.

Odell JA, Keller CA, Erasmus DB, Stritt MT.

Ann Thorac Surg. 2012 Feb;93(2):662-4. doi: 10.1016/j.athoracsur.2011.07.072.

PMID:
22269739
37.

European emissions of halogenated greenhouse gases inferred from atmospheric measurements.

Keller CA, Hill M, Vollmer MK, Henne S, Brunner D, Reimann S, O'Doherty S, Arduini J, Maione M, Ferenczi Z, Haszpra L, Manning AJ, Peter T.

Environ Sci Technol. 2012 Jan 3;46(1):217-25. doi: 10.1021/es202453j. Epub 2011 Dec 16.

PMID:
22192076
38.

Lung deflation and oxygen pulse in COPD: results from the NETT randomized trial.

Come CE, Divo MJ, San José Estépar R, Sciurba FC, Criner GJ, Marchetti N, Scharf SM, Mosenifar Z, Make BJ, Keller CA, Minai OA, Martinez FJ, Han MK, Reilly JJ, Celli BR, Washko GR; NETT Research Group.

Respir Med. 2012 Jan;106(1):109-19. doi: 10.1016/j.rmed.2011.07.012. Epub 2011 Aug 16.

39.

Dynamics of the epigenetic landscape during erythroid differentiation after GATA1 restoration.

Wu W, Cheng Y, Keller CA, Ernst J, Kumar SA, Mishra T, Morrissey C, Dorman CM, Chen KB, Drautz D, Giardine B, Shibata Y, Song L, Pimkin M, Crawford GE, Furey TS, Kellis M, Miller W, Taylor J, Schuster SC, Zhang Y, Chiaromonte F, Blobel GA, Weiss MJ, Hardison RC.

Genome Res. 2011 Oct;21(10):1659-71. doi: 10.1101/gr.125088.111. Epub 2011 Jul 27.

40.

Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis.

Thomas SR, Keller CA, Szyk A, Cannon JR, Laronde-Leblanc NA.

Nucleic Acids Res. 2011 Mar;39(6):2445-57. doi: 10.1093/nar/gkq1131. Epub 2010 Nov 17.

41.

Effects of administration of intravenous naloxone on gas exchange in brain-dead lung donors.

Eagan C, Keller CA, Baz MA, Thibault M.

Prog Transplant. 2009 Sep;19(3):267-71.

PMID:
19813490
42.

An alternative echocardiographic method to estimate mean pulmonary artery pressure: diagnostic and clinical implications.

Aduen JF, Castello R, Lozano MM, Hepler GN, Keller CA, Alvarez F, Safford RE, Crook JE, Heckman MG, Burger CD.

J Am Soc Echocardiogr. 2009 Jul;22(7):814-9. doi: 10.1016/j.echo.2009.04.007. Epub 2009 Jun 7.

PMID:
19505794
43.

Fatal arterial gas embolism in an adult 1 year after bilateral sequential lung transplantation.

Erasmus DB, Alvarez F, Keller CA.

J Heart Lung Transplant. 2008 Jun;27(6):692-4. doi: 10.1016/j.healun.2008.02.011. Epub 2008 Apr 9.

PMID:
18503973
44.

Safety of percutaneous dilatational tracheostomy with direct bronchoscopic guidance for solid organ allograft recipients.

Waller EA, Aduen JF, Kramer DJ, Alvarez F, Heckman MG, Crook JE, Pajaro OE, McBride LR, Keller CA.

Mayo Clin Proc. 2007 Dec;82(12):1502-8.

PMID:
18053458
45.
46.

GODZ-mediated palmitoylation of GABA(A) receptors is required for normal assembly and function of GABAergic inhibitory synapses.

Fang C, Deng L, Keller CA, Fukata M, Fukata Y, Chen G, Lüscher B.

J Neurosci. 2006 Dec 6;26(49):12758-68.

47.

Pharaoh Menes' death after an anaphylactic reaction--the end of a myth.

Krombach JW, Kampe S, Keller CA, Wright PM.

Allergy. 2004 Nov;59(11):1234-5. No abstract available.

PMID:
15461609
48.

Regulation of GABAA receptor trafficking, channel activity, and functional plasticity of inhibitory synapses.

Lüscher B, Keller CA.

Pharmacol Ther. 2004 Jun;102(3):195-221. Review.

PMID:
15246246
49.

The gamma2 subunit of GABA(A) receptors is a substrate for palmitoylation by GODZ.

Keller CA, Yuan X, Panzanelli P, Martin ML, Alldred M, Sassoè-Pognetto M, Lüscher B.

J Neurosci. 2004 Jun 30;24(26):5881-91.

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