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Items: 1 to 50 of 498

1.

Plasma mitochondrial DNA is associated with extrapulmonary sarcoidosis.

Ryu C, Brandsdorfer C, Adams T, Hu B, Kelleher DW, Yaggi M, Manning EP, Walia A, Reeves B, Pan H, Winkler J, Minasyan M, Dela Cruz CS, Kaminski N, Gulati M, Herzog EL.

Eur Respir J. 2019 Aug 29;54(2). pii: 1801762. doi: 10.1183/13993003.01762-2018. Print 2019 Aug.

PMID:
31273041
2.

A pilot study of the impact of Vitamin C supplementation with neoadjuvant chemoradiation on regulators of inflammation and carcinogenesis in esophageal cancer patients.

Abdel-Latif MMM, Babar M, Kelleher D, Reynolds JV.

J Cancer Res Ther. 2019 Jan-Mar;15(1):185-191. doi: 10.4103/jcrt.JCRT_763_16.

3.

Quantification of T-Cell Migratory Phenotypes Using High-Content Analysis.

Ng AS, Ong ST, Kelleher D, Verma NK.

Methods Mol Biol. 2019;1930:25-32. doi: 10.1007/978-1-4939-9036-8_4.

PMID:
30610595
4.

A Laboratory Model to Study T-Cell Motility.

Verma NK, Palapetta SM, Ong ST, Fazil MHUT, Chalasani MLS, Prasannan P, Kizhakeyil A, Kelleher D.

Methods Mol Biol. 2019;1930:19-23. doi: 10.1007/978-1-4939-9036-8_3.

PMID:
30610594
5.

An Introduction to LFA-1/ICAM-1 Interactions in T-Cell Motility.

Verma NK, Kelleher D.

Methods Mol Biol. 2019;1930:1-9. doi: 10.1007/978-1-4939-9036-8_1.

PMID:
30610592
6.

Euthanasia, religiosity and the valuation of health states: results from an Irish EQ5D5L valuation study and their implications for anchor values.

Barry L, Hobbins A, Kelleher D, Shah K, Devlin N, Goni JMR, O'Neill C.

Health Qual Life Outcomes. 2018 Jul 31;16(1):152. doi: 10.1186/s12955-018-0985-9.

7.

Utility Values for Health States in Ireland: A Value Set for the EQ-5D-5L.

Hobbins A, Barry L, Kelleher D, Shah K, Devlin N, Goni JMR, O'Neill C.

Pharmacoeconomics. 2018 Nov;36(11):1345-1353. doi: 10.1007/s40273-018-0690-x.

8.

siRNA Library Screening Identifies a Druggable Immune-Signature Driving Esophageal Adenocarcinoma Cell Growth.

Duggan SP, Garry C, Behan FM, Phipps S, Kudo H, Kirca M, Zaheer A, McGarrigle S, Reynolds JV, Goldin R, Kalloger SE, Schaeffer DF, Long A, Strid J, Kelleher D.

Cell Mol Gastroenterol Hepatol. 2018 Jan 31;5(4):569-590. doi: 10.1016/j.jcmgh.2018.01.012. eCollection 2018.

9.

Evidence of CD4+ T cell-mediated immune pressure on the Hepatitis C virus genome.

Lucas M, Deshpande P, James I, Rauch A, Pfafferott K, Gaylard E, Merani S, Plauzolles A, Lucas A, McDonnell W, Kalams S, Pilkinton M, Chastain C, Barnett L, Prosser A, Mallal S, Fitzmaurice K, Drummer H, Ansari MA, Pedergnana V, Barnes E, John M, Kelleher D, Klenerman P, Gaudieri S.

Sci Rep. 2018 May 8;8(1):7224. doi: 10.1038/s41598-018-25559-6.

10.

A rare presentation of pulmonary sarcoidosis as a solitary lung mass: a case report.

Kelleher DW, Yaggi M, Homer R, Herzog EL, Ryu C.

J Med Case Rep. 2018 Apr 13;12(1):94. doi: 10.1186/s13256-018-1632-0.

11.

Centrosome- and Golgi-Localized Protein Kinase N-Associated Protein Serves As a Docking Platform for Protein Kinase A Signaling and Microtubule Nucleation in Migrating T-Cells.

Ong ST, Chalasani MLS, Fazil MHUT, Prasannan P, Kizhakeyil A, Wright GD, Kelleher D, Verma NK.

Front Immunol. 2018 Mar 1;9:397. doi: 10.3389/fimmu.2018.00397. eCollection 2018.

12.

Bowel ischaemia after endovascular aneurysm repair.

Lowe C, El Bakbachi O, Kelleher D, Asghar I, Torella F, Antoniou GA.

Vasa. 2018 Jun;47(4):273-277. doi: 10.1024/0301-1526/a000698. Epub 2018 Mar 12. Review.

13.

Epidemiology of Sapovirus Infections in a Birth Cohort in Peru.

Sánchez GJ, Mayta H, Pajuelo MJ, Neira K, Xiaofang L, Cabrera L, Ballard SB, Crabtree JE, Kelleher D, Cama V, Bern C, Oshitani H, Gilman RH, Saito M; Sapovirus Working Group.

Clin Infect Dis. 2018 Jun 1;66(12):1858-1863. doi: 10.1093/cid/cix1103.

14.

Deoxycholic acid promotes development of gastroesophageal reflux disease and Barrett's oesophagus by modulating integrin-αv trafficking.

Prichard DO, Byrne AM, Murphy JO, Reynolds JV, O'Sullivan J, Feighery R, Doyle B, Eldin OS, Finn SP, Maguire A, Duff D, Kelleher DP, Long A.

J Cell Mol Med. 2017 Dec;21(12):3612-3625. doi: 10.1111/jcmm.13271. Epub 2017 Sep 22.

15.

Not Just an Adhesion Molecule: LFA-1 Contact Tunes the T Lymphocyte Program.

Verma NK, Kelleher D.

J Immunol. 2017 Aug 15;199(4):1213-1221. doi: 10.4049/jimmunol.1700495. Review.

16.

Erratum to: Surface layer proteins from virulent Clostridium difficile ribotypes exhibit signatures of positive selection with consequences for innate immune response.

Lynch M, Walsh TA, Marszalowska I, Webb AE, Mac Aogáin M, Rogers TR, Windle H, Kelleher D, O'Connell MJ, Loscher CE.

BMC Evol Biol. 2017 Jun 12;17(1):135. doi: 10.1186/s12862-017-0990-3. No abstract available.

17.

Surface layer proteins from virulent Clostridium difficile ribotypes exhibit signatures of positive selection with consequences for innate immune response.

Lynch M, Walsh TA, Marszalowska I, Webb AE, Mac Aogain M, Rogers TR, Windle H, Kelleher D, O'Connell MJ, Loscher CE.

BMC Evol Biol. 2017 Mar 23;17(1):90. doi: 10.1186/s12862-017-0937-8. Erratum in: BMC Evol Biol. 2017 Jun 12;17 (1):135.

18.

International, evidence-based consensus diagnostic criteria for HHV-8-negative/idiopathic multicentric Castleman disease.

Fajgenbaum DC, Uldrick TS, Bagg A, Frank D, Wu D, Srkalovic G, Simpson D, Liu AY, Menke D, Chandrakasan S, Lechowicz MJ, Wong RS, Pierson S, Paessler M, Rossi JF, Ide M, Ruth J, Croglio M, Suarez A, Krymskaya V, Chadburn A, Colleoni G, Nasta S, Jayanthan R, Nabel CS, Casper C, Dispenzieri A, Fosså A, Kelleher D, Kurzrock R, Voorhees P, Dogan A, Yoshizaki K, van Rhee F, Oksenhendler E, Jaffe ES, Elenitoba-Johnson KS, Lim MS.

Blood. 2017 Mar 23;129(12):1646-1657. doi: 10.1182/blood-2016-10-746933. Epub 2017 Jan 13.

19.

Carotid endarterectomy following thrombolysis for acute ischaemic stroke.

Ahmed N, Kelleher D, Madan M, Sochart S, Antoniou GA.

Vasa. 2017 Mar;46(2):116-120. doi: 10.1024/0301-1526/a000601. Epub 2017 Jan 3.

20.

GapmeR cellular internalization by macropinocytosis induces sequence-specific gene silencing in human primary T-cells.

Fazil MH, Ong ST, Chalasani ML, Low JH, Kizhakeyil A, Mamidi A, Lim CF, Wright GD, Lakshminarayanan R, Kelleher D, Verma NK.

Sci Rep. 2016 Nov 24;6:37721. doi: 10.1038/srep37721.

21.

Does the use of a hybrid theatre in vascular surgery result in improved clinical outcomes and radiation protection?

McANELLY SL, Kelleher D, Ibrahim R, Antoniou GA.

Int Angiol. 2017 Jun;36(3):289-292. doi: 10.23736/S0392-9590.16.03738-X. Epub 2016 Nov 24. No abstract available.

22.

Corrigendum: The characterization of an intestine-like genomic signature maintained during Barrett's-associated adenocarcinogenesis reveals an NR5A2-mediated promotion of cancer cell survival.

Duggan SP, Behan FM, Kirca M, Zaheer A, McGarrigle SA, Reynolds JV, Vaz GM, Senge MO, Kelleher D.

Sci Rep. 2016 Oct 14;6:35330. doi: 10.1038/srep35330. No abstract available.

23.

The characterization of an intestine-like genomic signature maintained during Barrett's-associated adenocarcinogenesis reveals an NR5A2-mediated promotion of cancer cell survival.

Duggan SP, Behan FM, Kirca M, Zaheer A, McGarrigle SA, Reynolds JV, Vaz GM, Senge MO, Kelleher D.

Sci Rep. 2016 Sep 2;6:32638. doi: 10.1038/srep32638. Erratum in: Sci Rep. 2016 Oct 14;6:35330.

24.

Correction: LFA-1/ICAM-1 Ligation in Human T Cells Promotes Th1 Polarization through a GSK3β Signaling-Dependent Notch Pathway.

Verma NK, Fazil MH, Ong ST, Chalasani ML, Low JH, Kottaiswamy A, P P, Kizhakeyil A, Kumar S, Panda AK, Freeley M, Smith SM, Boehm BO, Kelleher D.

J Immunol. 2016 Sep 1;197(5):2039-40. doi: 10.4049/jimmunol.1601160. No abstract available.

25.

Meta-analysis of posterior versus medial approach for popliteal artery aneurysm repair.

Phair A, Hajibandeh S, Hajibandeh S, Kelleher D, Ibrahim R, Antoniou GA.

J Vasc Surg. 2016 Oct;64(4):1141-1150.e1. doi: 10.1016/j.jvs.2016.05.064. Epub 2016 Jul 26. Review.

26.

Differential modulation of Helicobacter pylori lipopolysaccharide-mediated TLR2 signaling by individual Pellino proteins.

Smith SM, Freeley M, Moynagh PN, Kelleher DP.

Helicobacter. 2017 Feb;22(1). doi: 10.1111/hel.12325. Epub 2016 Jun 15.

PMID:
27302665
27.

LFA-1/ICAM-1 Ligation in Human T Cells Promotes Th1 Polarization through a GSK3β Signaling-Dependent Notch Pathway.

Verma NK, Fazil MH, Ong ST, Chalasani ML, Low JH, Kottaiswamy A, P P, Kizhakeyil A, Kumar S, Panda AK, Freeley M, Smith SM, Boehm BO, Kelleher D.

J Immunol. 2016 Jul 1;197(1):108-18. doi: 10.4049/jimmunol.1501264. Epub 2016 May 20. Erratum in: J Immunol. 2016 Sep 1;197(5):2039-40.

28.

Etiological Role and Repeated Infections of Sapovirus among Children Aged Less than 2 Years in a Cohort Study in a Peri-urban Community of Peru.

Liu X, Jahuira H, Gilman RH, Alva A, Cabrera L, Okamoto M, Xu H, Windle HJ, Kelleher D, Varela M, Verastegui M, Calderon M, Sanchez G, Sarabia V, Ballard SB, Bern C, Mayta H, Crabtree JE, Cama V, Saito M, Oshitani H.

J Clin Microbiol. 2016 Jun;54(6):1598-1604. doi: 10.1128/JCM.03133-15. Epub 2016 Apr 13.

29.

Factors regulating nuclear factor-kappa B activation in esophageal cancer cells: Role of bile acids and acid.

Abdel-Latif MM, Inoue H, Kelleher D, Reynolds JV.

J Cancer Res Ther. 2016 Jan-Mar;12(1):364-73. doi: 10.4103/0973-1482.174525.

30.

Idiopathic multicentric Castleman's disease: a systematic literature review.

Liu AY, Nabel CS, Finkelman BS, Ruth JR, Kurzrock R, van Rhee F, Krymskaya VP, Kelleher D, Rubenstein AH, Fajgenbaum DC.

Lancet Haematol. 2016 Apr;3(4):e163-75. doi: 10.1016/S2352-3026(16)00006-5. Epub 2016 Mar 17. Review.

PMID:
27063975
31.

The collaborative network approach: a new framework to accelerate Castleman's disease and other rare disease research.

Fajgenbaum DC, Ruth JR, Kelleher D, Rubenstein AH.

Lancet Haematol. 2016 Apr;3(4):e150-2. doi: 10.1016/S2352-3026(16)00007-7. Epub 2016 Mar 17. No abstract available.

PMID:
27063967
32.

Modelling subject-specific childhood growth using linear mixed-effect models with cubic regression splines.

Grajeda LM, Ivanescu A, Saito M, Crainiceanu C, Jaganath D, Gilman RH, Crabtree JE, Kelleher D, Cabrera L, Cama V, Checkley W.

Emerg Themes Epidemiol. 2016 Jan 7;13:1. doi: 10.1186/s12982-015-0038-3. eCollection 2016.

33.

Golgi phosphoprotein 2 (GOLPH2) is a novel bile acid-responsive modulator of oesophageal cell migration and invasion.

Byrne AM, Bekiaris S, Duggan G, Prichard D, Kirca M, Finn S, Reynolds JV, Kelleher D, Long A.

Br J Cancer. 2015 Nov 3;113(9):1332-42. doi: 10.1038/bjc.2015.350. Epub 2015 Oct 13.

34.

Pgc-1α and Nr4a1 Are Target Genes of Circadian Melatonin and Dopamine Release in Murine Retina.

Kunst S, Wolloscheck T, Kelleher DK, Wolfrum U, Sargsyan SA, Iuvone PM, Baba K, Tosini G, Spessert R.

Invest Ophthalmol Vis Sci. 2015 Sep;56(10):6084-94. doi: 10.1167/iovs.15-17503.

35.

Effect of Disease Severity in Asthma and Chronic Obstructive Pulmonary Disease on Inhaler-Specific Inhalation Profiles Through the ELLIPTA® Dry Powder Inhaler.

Prime D, de Backer W, Hamilton M, Cahn A, Preece A, Kelleher D, Baines A, Moore A, Brealey N, Moynihan J.

J Aerosol Med Pulm Drug Deliv. 2015 Dec;28(6):486-97. doi: 10.1089/jamp.2015.1224. Epub 2015 Sep 15.

36.

Transcriptional regulation of nucleoredoxin-like genes takes place on a daily basis in the retina and pineal gland of rats.

Wolloscheck T, Kunst S, Kelleher DK, Spessert R.

Vis Neurosci. 2015 Jan;32:E002. doi: 10.1017/S0952523814000352.

PMID:
26239254
37.

RNAi Screening with Self-Delivering, Synthetic siRNAs for Identification of Genes That Regulate Primary Human T Cell Migration.

Freeley M, Derrick E, Dempsey E, Hoff A, Davies A, Leake D, Vermeulen A, Kelleher D, Long A.

J Biomol Screen. 2015 Sep;20(8):943-56. doi: 10.1177/1087057115588288. Epub 2015 May 29.

PMID:
26024944
38.

Common polygenic variation in coeliac disease and confirmation of ZNF335 and NIFA as disease susceptibility loci.

Coleman C, Quinn EM, Ryan AW, Conroy J, Trimble V, Mahmud N, Kennedy N, Corvin AP, Morris DW, Donohoe G, O'Morain C, MacMathuna P, Byrnes V, Kiat C, Trynka G, Wijmenga C, Kelleher D, Ennis S, Anney RJ, McManus R.

Eur J Hum Genet. 2016 Feb;24(2):291-7. doi: 10.1038/ejhg.2015.87. Epub 2015 Apr 29.

39.

Molecular mechanisms of constitutive and inducible NF-kappaB activation in oesophageal adenocarcinoma.

Abdel-Latif MM, Kelleher D, Reynolds JV.

Eur J Cancer. 2015 Mar;51(4):464-72. doi: 10.1016/j.ejca.2014.11.014. Epub 2015 Jan 14.

PMID:
25596807
40.

Effect of severe renal impairment on umeclidinium and umeclidinium/vilanterol pharmacokinetics and safety: a single-blind, nonrandomized study.

Mehta R, Hardes K, Brealey N, Tombs L, Preece A, Kelleher D.

Int J Chron Obstruct Pulmon Dis. 2014 Dec 18;10:15-23. doi: 10.2147/COPD.S68094. eCollection 2015.

41.

Polymorphisms near TBX5 and GDF7 are associated with increased risk for Barrett's esophagus.

Palles C, Chegwidden L, Li X, Findlay JM, Farnham G, Castro Giner F, Peppelenbosch MP, Kovac M, Adams CL, Prenen H, Briggs S, Harrison R, Sanders S, MacDonald D, Haigh C, Tucker A, Love S, Nanji M, deCaestecker J, Ferry D, Rathbone B, Hapeshi J, Barr H, Moayyedi P, Watson P, Zietek B, Maroo N, Gay L, Underwood T, Boulter L, McMurtry H, Monk D, Patel P, Ragunath K, Al Dulaimi D, Murray I, Koss K, Veitch A, Trudgill N, Nwokolo C, Rembacken B, Atherfold P, Green E, Ang Y, Kuipers EJ, Chow W, Paterson S, Kadri S, Beales I, Grimley C, Mullins P, Beckett C, Farrant M, Dixon A, Kelly S, Johnson M, Wajed S, Dhar A, Sawyer E, Roylance R, Onstad L, Gammon MD, Corley DA, Shaheen NJ, Bird NC, Hardie LJ, Reid BJ, Ye W, Liu G, Romero Y, Bernstein L, Wu AH, Casson AG, Fitzgerald R, Whiteman DC, Risch HA, Levine DM, Vaughan TL, Verhaar AP, van den Brande J, Toxopeus EL, Spaander MC, Wijnhoven BP, van der Laan LJ, Krishnadath K, Wijmenga C, Trynka G, McManus R, Reynolds JV, O'Sullivan J, MacMathuna P, McGarrigle SA, Kelleher D, Vermeire S, Cleynen I, Bisschops R, Tomlinson I, Jankowski J.

Gastroenterology. 2015 Feb;148(2):367-78. doi: 10.1053/j.gastro.2014.10.041. Epub 2014 Nov 5.

42.

Effect of a checklist on advanced trauma life support task performance during pediatric trauma resuscitation.

Kelleher DC, Carter EA, Waterhouse LJ, Parsons SE, Fritzeen JL, Burd RS.

Acad Emerg Med. 2014 Oct;21(10):1129-34. doi: 10.1111/acem.12487.

43.

Adaptor regulation of LFA-1 signaling in T lymphocyte migration: Potential druggable targets for immunotherapies?

Verma NK, Kelleher D.

Eur J Immunol. 2014 Dec;44(12):3484-99. doi: 10.1002/eji.201344428. Epub 2014 Oct 30. Review.

44.

Little association between wellness policies and school-reported nutrition practices.

Lucarelli JF, Alaimo K, Belansky ES, Mang E, Miles R, Kelleher DK, Bailey D, Drzal NB, Liu H.

Health Promot Pract. 2015 Mar;16(2):193-201. doi: 10.1177/1524839914550245. Epub 2014 Sep 23.

45.

Polymorphisms in melanoma differentiation-associated gene 5 link protein function to clearance of hepatitis C virus.

Hoffmann FS, Schmidt A, Dittmann Chevillotte M, Wisskirchen C, Hellmuth J, Willms S, Gilmore RH, Glas J, Folwaczny M, Müller T, Berg T, Spengler U, Fitzmaurice K, Kelleher D, Reisch N, Rice CM, Endres S, Rothenfusser S.

Hepatology. 2015 Feb;61(2):460-70. doi: 10.1002/hep.27344. Epub 2015 Jan 5.

46.

Facilitators to promoting health in schools: is school health climate the key?

Lucarelli JF, Alaimo K, Mang E, Martin C, Miles R, Bailey D, Kelleher DK, Drzal NB, Liu H.

J Sch Health. 2014 Feb;84(2):133-40. doi: 10.1111/josh.12123.

47.

Effects of water-filtered infrared-A and of heat on cell death, inflammation, antioxidative potential and of free radical formation in viable skin--first results.

Piazena H, Pittermann W, Müller W, Jung K, Kelleher DK, Herrling T, Meffert P, Uebelhack R, Kietzmann M.

J Photochem Photobiol B. 2014 Sep 5;138:347-54. doi: 10.1016/j.jphotobiol.2014.06.007. Epub 2014 Jun 30.

PMID:
25038541
48.

A randomized, placebo- and moxifloxacin-controlled thorough QT study of umeclidinium monotherapy and umeclidinium/vilanterol combination in healthy subjects.

Kelleher D, Tombs L, Preece A, Brealey N, Mehta R.

Pulm Pharmacol Ther. 2014 Oct;29(1):49-57. doi: 10.1016/j.pupt.2014.07.002. Epub 2014 Jul 12.

PMID:
25020273
49.

Articulating the value of health research.

Fears R, Kelleher D, Tresguerres JA, Charpentier B, Popescu I, Souhami R.

QJM. 2014 Aug;107(8):603-5. doi: 10.1093/qjmed/hcu132. Epub 2014 Jun 26.

PMID:
24970762
50.

Ambulatory varicosity avulsion later or synchronized (AVULS): a randomized clinical trial.

Lane TR, Kelleher D, Shepherd AC, Franklin IJ, Davies AH.

Ann Surg. 2015 Apr;261(4):654-61. doi: 10.1097/SLA.0000000000000790.

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