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Select item 316210731.

Impact of HIV-1 viremia or sexually transmitted infection on semen-derived anti-HIV-1 antibodies and the immunosuppressive capacity of seminal plasma.

Selva KJ, Bavinton BR, Grulich AE, Pazgier M, Kelleher AD, Kent SJ, Parsons MS.

Eur J Immunol. 2019 Oct 16. doi: 10.1002/eji.201848055. [Epub ahead of print] No abstract available.

PMID:: 31621073

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Select item 311919102.

Possible clearance of transfusion-acquired nef/LTR-deleted attenuated HIV-1 infection by an elite controller with CCR5 Δ32 heterozygous and HLA-B57 genotype.

Zaunders J, Dyer WB, Churchill M, Munier CML, Cunningham PH, Suzuki K, McBride K, Hey-Nguyen W, Koelsch K, Wang B, Hiener B, Palmer S, Gorry PR, Bailey M, Xu Y, Danta M, Seddiki N, Cooper DA, Saksena NK, Sullivan JS, Riminton S, Learmont J, Kelleher AD.

J Virus Erad. 2019 Apr 1;5(2):73-83.

PMID:: 31191910

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Select item 311378363.

Limited Sustained Local Transmission of HIV-1 CRF01_AE in New South Wales, Australia.

Di Giallonardo F, Pinto AN, Keen P, Shaik A, Carrera A, Salem H, Telfer B, Cooper C, Price K, Selvey C, Holden J, Bachmann N, Lee FJ, Dwyer DE, Duchêne S, Holmes EC, Grulich AE, Kelleher AD.

Viruses. 2019 May 27;11(5). pii: E482. doi: 10.3390/v11050482.

PMID:: 31137836

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Select item 309528874.

Mucosal and systemic SIV-specific cytotoxic CD4⁺ T cell hierarchy in protection following intranasal/intramuscular recombinant pox-viral vaccination of pigtail macaques.

Khanna M, Jackson RJ, Alcantara S, Amarasena TH, Li Z, Kelleher AD, Kent SJ, Ranasinghe C.

Sci Rep. 2019 Apr 5;9(1):5661. doi: 10.1038/s41598-019-41506-5.

PMID:: 30952887

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Select item 309361335.

Caring Practices May Save a Life.

Knippa S, Leyes L, Kelleher AD, Popies J.

Crit Care Nurse. 2019 Apr;39(2):94-98. doi: 10.4037/ccn2019844. No abstract available.

PMID:: 30936133

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Select item 308673076.

Modulation of the CCR5 Receptor/Ligand Axis by Seminal Plasma and the Utility of In Vitro versus In Vivo Models.

Juno JA, Wragg KM, Kristensen AB, Lee WS, Selva KJ, van der Sluis RM, Kelleher AD, Bavinton BR, Grulich AE, Lewin SR, Kent SJ, Parsons MS.

J Virol. 2019 May 15;93(11). pii: e00242-19. doi: 10.1128/JVI.00242-19. Print 2019 Jun 1.

PMID:: 30867307

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Select item 305118787.

HIV-1 DNA Is Maintained in Antigen-Specific CD4+ T Cell Subsets in Patients on Long-Term Antiretroviral Therapy Regardless of Recurrent Antigen Exposure.

Hey-Nguyen WJ, Bailey M, Xu Y, Suzuki K, Van Bockel D, Finlayson R, Leigh Brown A, Carr A, Cooper DA, Kelleher AD, Koelsch KK, Zaunders JJ.

AIDS Res Hum Retroviruses. 2019 Jan;35(1):112-120. doi: 10.1089/AID.2018.0235.

PMID:: 30511878

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Select item 304101268.

Functional cure of HIV: the scale of the challenge.

Davenport MP, Khoury DS, Cromer D, Lewin SR, Kelleher AD, Kent SJ.

Nat Rev Immunol. 2019 Jan;19(1):45-54. doi: 10.1038/s41577-018-0085-4.

PMID:: 30410126

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Select item 302867649.

RNA-induced epigenetic silencing inhibits HIV-1 reactivation from latency.

Méndez C, Ledger S, Petoumenos K, Ahlenstiel C, Kelleher AD.

Retrovirology. 2018 Oct 4;15(1):67. doi: 10.1186/s12977-018-0451-0.

PMID:: 30286764

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Select item 3013542910.

Memory B cells are reactivated in subcapsular proliferative foci of lymph nodes.

Moran I, Nguyen A, Khoo WH, Butt D, Bourne K, Young C, Hermes JR, Biro M, Gracie G, Ma CS, Munier CML, Luciani F, Zaunders J, Parker A, Kelleher AD, Tangye SG, Croucher PI, Brink R, Read MN, Phan TG.

Nat Commun. 2018 Aug 22;9(1):3372. doi: 10.1038/s41467-018-05772-7.

PMID:: 30135429

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Select item 2990141511.

Early Treatment of Primary HIV Infection Is Associated with Decreased Mortality.

Pinto AN, Grey P, Shaik A, Cooper DA, Kelleher AD, Petoumenos K.

AIDS Res Hum Retroviruses. 2018 Nov;34(11):936-941. doi: 10.1089/AID.2017.0284. Epub 2018 Jul 17.

PMID:: 29901415

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Select item 2960523112.

Neutrophils mediate HIV-specific antibody-dependent phagocytosis and ADCC.

Worley MJ, Fei K, Lopez-Denman AJ, Kelleher AD, Kent SJ, Chung AW.

J Immunol Methods. 2018 Jun;457:41-52. doi: 10.1016/j.jim.2018.03.007. Epub 2018 Mar 29.

PMID:: 29605231

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Select item 2935033813.

Reversible Suppression of Lymphoproliferation and Thrombocytopenia with Rapamycin in a Patient with Common Variable Immunodeficiency.

Deenick EK, Morey A, Danta M, Emmett L, Fay K, Gracie G, Ma CS, Macintosh R, Smith SABC, Sasson SC, Sewell WA, Cowley M, Tangye SG, Kelleher AD; CIRCA, Phan TG.

J Clin Immunol. 2018 Feb;38(2):159-162. doi: 10.1007/s10875-018-0477-z. Epub 2018 Jan 19. No abstract available.

PMID:: 29350338

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Select item 2904933114.

HIV dynamics linked to memory CD4+ T cell homeostasis.

Murray JM, Zaunders J, Emery S, Cooper DA, Hey-Nguyen WJ, Koelsch KK, Kelleher AD.

PLoS One. 2017 Oct 19;12(10):e0186101. doi: 10.1371/journal.pone.0186101. eCollection 2017.

PMID:: 29049331

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Select item 2896875515.

Evaluating the Impact of Functional Genetic Variation on HIV-1 Control.

McLaren PJ, Pulit SL, Gurdasani D, Bartha I, Shea PR, Pomilla C, Gupta N, Gkrania-Klotsas E, Young EH, Bannert N, Del Amo J, Gill MJ, Gilmour J, Kellam P, Kelleher AD, Sönnerborg A, Zangerle R, Post FA, Fisher M, Haas DW, Walker BD, Porter K, Goldstein DB, Sandhu MS, de Bakker PIW, Fellay J.

J Infect Dis. 2017 Nov 27;216(9):1063-1069. doi: 10.1093/infdis/jix470. Erratum in: J Infect Dis. 2018 Jun 5;218(1):171.

PMID:: 28968755

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Select item 2888364716.

Circulating miR-122 and miR-200a as biomarkers for fatal liver disease in ART-treated, HIV-1-infected individuals.

Murray DD, Suzuki K, Law M, Trebicka J, Neuhaus Nordwall J, Johnson M, Vjecha MJ, Kelleher AD, Emery S.

Sci Rep. 2017 Sep 7;7(1):10934. doi: 10.1038/s41598-017-11405-8.

PMID:: 28883647

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Select item 2876886717.

Mechanism of Interferon-Stimulated Gene Induction in HIV-1-Infected Macrophages.

Nasr N, Alshehri AA, Wright TK, Shahid M, Heiner BM, Harman AN, Botting RA, Helbig KJ, Beard MR, Suzuki K, Kelleher AD, Hertzog P, Cunningham AL.

J Virol. 2017 Sep 27;91(20). pii: e00744-17. doi: 10.1128/JVI.00744-17. Print 2017 Oct 15.

PMID:: 28768867

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Select item 2855328418.

Divergent Expression of CXCR5 and CCR5 on CD4⁺ T Cells and the Paradoxical Accumulation of T Follicular Helper Cells during HIV Infection.

Zaunders J, Xu Y, Kent SJ, Koelsch KK, Kelleher AD.

Front Immunol. 2017 May 12;8:495. doi: 10.3389/fimmu.2017.00495. eCollection 2017. Review.

PMID:: 28553284

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Select item 2848538219.

Single-cell profiling of lineage determining transcription factors in antigen-specific CD4⁺ T cells reveals unexpected complexity in recall responses during immune reconstitution.

Phetsouphanh C, Xu Y, Munier ML, Zaunders JJ, Kelleher AD.

Immunol Cell Biol. 2017 Aug;95(7):640-646. doi: 10.1038/icb.2017.28. Epub 2017 May 9.

PMID:: 28485382

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Select item 2848444720.

HIV-1 and SIV Predominantly Use CCR5 Expressed on a Precursor Population to Establish Infection in T Follicular Helper Cells.

Xu Y, Phetsouphanh C, Suzuki K, Aggrawal A, Graff-Dubois S, Roche M, Bailey M, Alcantara S, Cashin K, Sivasubramaniam R, Koelsch KK, Autran B, Harvey R, Gorry PR, Moris A, Cooper DA, Turville S, Kent SJ, Kelleher AD, Zaunders J.

Front Immunol. 2017 Apr 21;8:376. doi: 10.3389/fimmu.2017.00376. eCollection 2017.

PMID:: 28484447

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Select item 2847453421.

Evolution of HIV-1 surveillance drug resistance mutations over ten years in New South Wales, Australia.

Pinto A, Carrera A, Salem H, Thapa K, Shaik A, Petoumenos K, Cunningham P, Garsia R, Dwyer D, Cooper DA, Kelleher AD.

AIDS Res Hum Retroviruses. 2017 May 5. doi: 10.1089/AID.2016.0301. [Epub ahead of print]

PMID:: 28474534

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Select item 2844031222.

Expanding role for type I Interferons in restricting HIV growth.

Kent SJ, Kelleher AD.

Immunol Cell Biol. 2017 May;95(5):417-418. doi: 10.1038/icb.2017.15. Epub 2017 Apr 25. No abstract available.

PMID:: 28440312

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Select item 2835055323.

Impact of Allogeneic Hematopoietic Stem Cell Transplantation on the HIV Reservoir and Immune Response in 3 HIV-Infected Individuals.

Koelsch KK, Rasmussen TA, Hey-Nguyen WJ, Pearson C, Xu Y, Bailey M, Marks KH, Sasson SC, Taylor MS, Tantau R, Obeid S, Milner B, Morrissey O, Pinto AN, Suzuki K, Busch MP, Keating SM, Kaiser P, Yukl S, Wong JK, Hiener BM, Palmer S, Zaunders J, Post JJ, Chan DJ, Avery S, Milliken ST, Kelleher AD, Lewin SR, Cooper DA.

J Acquir Immune Defic Syndr. 2017 Jul 1;75(3):328-337. doi: 10.1097/QAI.0000000000001381.

PMID:: 28350553

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Select item 2828782524.

Quantification of Residual Germinal Center Activity and HIV-1 DNA and RNA Levels Using Fine Needle Biopsies of Lymph Nodes During Antiretroviral Therapy.

Hey-Nguyen WJ, Xu Y, Pearson CF, Bailey M, Suzuki K, Tantau R, Obeid S, Milner B, Field A, Carr A, Bloch M, Cooper DA, Kelleher AD, Zaunders JJ, Koelsch KK.

AIDS Res Hum Retroviruses. 2017 Jul;33(7):648-657. doi: 10.1089/aid.2016.0171. Epub 2017 Mar 13.

PMID:: 28287825

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Select item 2828341925.

Circulating gluten-specific FOXP3⁺CD39⁺ regulatory T cells have impaired suppressive function in patients with celiac disease.

Cook L, Munier CML, Seddiki N, van Bockel D, Ontiveros N, Hardy MY, Gillies JK, Levings MK, Reid HH, Petersen J, Rossjohn J, Anderson RP, Zaunders JJ, Tye-Din JA, Kelleher AD.

J Allergy Clin Immunol. 2017 Dec;140(6):1592-1603.e8. doi: 10.1016/j.jaci.2017.02.015. Epub 2017 Mar 8.

PMID:: 28283419

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Select item 2818720426.

Differentiating founder and chronic HIV envelope sequences.

Murray JM, Maher S, Mota T, Suzuki K, Kelleher AD, Center RJ, Purcell D.

PLoS One. 2017 Feb 10;12(2):e0171572. doi: 10.1371/journal.pone.0171572. eCollection 2017.

PMID:: 28187204

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Select item 2816794327.

Cytotoxic CD4 T Cells-Friend or Foe during Viral Infection?

Juno JA, van Bockel D, Kent SJ, Kelleher AD, Zaunders JJ, Munier CM.

Front Immunol. 2017 Jan 23;8:19. doi: 10.3389/fimmu.2017.00019. eCollection 2017. Review.

PMID:: 28167943

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Select item 2794159528.

Achieving HIV-1 Control through RNA-Directed Gene Regulation.

Klemm V, Mitchell J, Cortez-Jugo C, Cavalieri F, Symonds G, Caruso F, Kelleher AD, Ahlenstiel C.

Genes (Basel). 2016 Dec 7;7(12). pii: E119. Review.

PMID:: 27941595

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Select item 2782221129.

CD4⁺ T Follicular Helper and IgA⁺ B Cell Numbers in Gut Biopsies from HIV-Infected Subjects on Antiretroviral Therapy Are Similar to HIV-Uninfected Individuals.

Zaunders J, Danta M, Bailey M, Mak G, Marks K, Seddiki N, Xu Y, Templeton DJ, Cooper DA, Boyd MA, Kelleher AD, Koelsch KK.

Front Immunol. 2016 Oct 24;7:438. eCollection 2016.

PMID:: 27822211

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Select item 2779062530.

The feasibility of incorporating Vpx into lentiviral gene therapy vectors.

McAllery SA, Ahlenstiel CL, Suzuki K, Symonds GP, Kelleher AD, Turville SG.

Mol Ther Methods Clin Dev. 2016 Oct 19;5:16066. eCollection 2016.

PMID:: 27790625

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Select item 2763928131.

The primary immune response to Vaccinia virus vaccination includes cells with a distinct cytotoxic effector CD4 T-cell phenotype.

Munier CML, van Bockel D, Bailey M, Ip S, Xu Y, Alcantara S, Liu SM, Denyer G, Kaplan W; PHIIDO Study group, Suzuki K, Croft N, Purcell A, Tscharke D, Cooper DA, Kent SJ, Zaunders JJ, Kelleher AD.

Vaccine. 2016 Oct 17;34(44):5251-5261. doi: 10.1016/j.vaccine.2016.09.009. Epub 2016 Sep 14.

PMID:: 27639281

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Select item 2763893532.

Comment on "A Cytokine-Independent Approach To Identify Antigen-Specific Human Germinal Center T Follicular Helper Cells and Rare Antigen-Specific CD4+ T Cells in Blood".

Cook L, Zaunders JJ, Kelleher AD.

J Immunol. 2016 Oct 1;197(7):2557-8. doi: 10.4049/jimmunol.1601311. No abstract available.

PMID:: 27638935

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Select item 2760329133.

Control of early HIV-1 infection associates with plasmacytoid dendritic cell-reactive opsonophagocytic IgG antibodies to HIV-1 p24.

Tjiam MC, Sariputra L, Armitage JD, Taylor JP, Kelleher AD, Tan DB, Lee S, Fernandez S, French MA.

AIDS. 2016 Nov 28;30(18):2757-2765.

PMID:: 27603291

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Select item 2756108234.

Correction: HIV Reactivation from Latency after Treatment Interruption Occurs on Average Every 5-8 Days-Implications for HIV Remission.

Pinkevych M, Cromer D, Tolstrup M, Grimm AJ, Cooper DA, Lewin SR, Søgaard OS, Rasmussen TA, Kent SJ, Kelleher AD, Davenport MP.

PLoS Pathog. 2016 Aug 25;12(8):e1005745. doi: 10.1371/journal.ppat.1005745. eCollection 2016 Aug.

PMID:: 27561082

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Select item 2756097235.

Modeling of Experimental Data Supports HIV Reactivation from Latency after Treatment Interruption on Average Once Every 5-8 Days.

Pinkevych M, Kent SJ, Tolstrup M, Lewin SR, Cooper DA, Søgaard OS, Rasmussen TA, Kelleher AD, Cromer D, Davenport MP.

PLoS Pathog. 2016 Aug 25;12(8):e1005740. doi: 10.1371/journal.ppat.1005740. eCollection 2016 Aug. No abstract available.

PMID:: 27560972

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Select item 2714992236.

Nuclear PKC-θ facilitates rapid transcriptional responses in human memory CD4+ T cells through p65 and H2B phosphorylation.

Li J, Hardy K, Phetsouphanh C, Tu WJ, Sutcliffe EL, McCuaig R, Sutton CR, Zafar A, Munier CM, Zaunders JJ, Xu Y, Theodoratos A, Tan A, Lim PS, Knaute T, Masch A, Zerweck J, Brezar V, Milburn PJ, Dunn J, Casarotto MG, Turner SJ, Seddiki N, Kelleher AD, Rao S.

J Cell Sci. 2016 Jun 15;129(12):2448-61. doi: 10.1242/jcs.181248. Epub 2016 May 5.

PMID:: 27149922

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Select item 2684567537.

Immune activation and immune aging in HIV infection.

Appay V, Kelleher AD.

Curr Opin HIV AIDS. 2016 Mar;11(2):242-9. doi: 10.1097/COH.0000000000000240. Review.

PMID:: 26845675

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Select item 2663692538.

The impact of transient combination antiretroviral treatment in early HIV infection on viral suppression and immunologic response in later treatment.

Pantazis N, Touloumi G, Meyer L, Olson A, Costagliola D, Kelleher AD, Lutsar I, Chaix ML, Fisher M, Moreno S, Porter K; CASCADE Collaboration in EuroCoord.

AIDS. 2016 Mar 27;30(6):879-88. doi: 10.1097/QAD.0000000000000991.

PMID:: 26636925

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Select item 2650603939.

Novel RNA Duplex Locks HIV-1 in a Latent State via Chromatin-mediated Transcriptional Silencing.

Ahlenstiel C, Mendez C, Lim ST, Marks K, Turville S, Cooper DA, Kelleher AD, Suzuki K.

Mol Ther Nucleic Acids. 2015 Oct 27;4:e261. doi: 10.1038/mtna.2015.31.

PMID:: 26506039

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Select item 2650142440.

HIV-Infected Spleens Present Altered Follicular Helper T Cell (Tfh) Subsets and Skewed B Cell Maturation.

Colineau L, Rouers A, Yamamoto T, Xu Y, Urrutia A, Pham HP, Cardinaud S, Samri A, Dorgham K, Coulon PG, Cheynier R, Hosmalin A, Oksenhendler E, Six A, Kelleher AD, Zaunders J, Koup RA, Autran B, Moris A, Graff-Dubois S.

PLoS One. 2015 Oct 26;10(10):e0140978. doi: 10.1371/journal.pone.0140978. eCollection 2015.

PMID:: 26501424

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Select item 2646529341.

Circulating microRNAs in Sera Correlate with Soluble Biomarkers of Immune Activation but Do Not Predict Mortality in ART Treated Individuals with HIV-1 Infection: A Case Control Study.

Murray DD, Suzuki K, Law M, Trebicka J, Neuhaus J, Wentworth D, Johnson M, Vjecha MJ, Kelleher AD, Emery S; INSIGHT ESPRIT and SMART Study Groups.

PLoS One. 2015 Oct 14;10(10):e0139981. doi: 10.1371/journal.pone.0139981. eCollection 2015.

PMID:: 26465293

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Select item 2644916442.

Immunological biomarkers predict HIV-1 viral rebound after treatment interruption.

Hurst J, Hoffmann M, Pace M, Williams JP, Thornhill J, Hamlyn E, Meyerowitz J, Willberg C, Koelsch KK, Robinson N, Brown H, Fisher M, Kinloch S, Cooper DA, Schechter M, Tambussi G, Fidler S, Babiker A, Weber J, Kelleher AD, Phillips RE, Frater J.

Nat Commun. 2015 Oct 9;6:8495. doi: 10.1038/ncomms9495.

PMID:: 26449164

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Select item 2644197943.

Controlling HIV-1: Non-Coding RNA Gene Therapy Approaches to a Functional Cure.

Ahlenstiel CL, Suzuki K, Marks K, Symonds GP, Kelleher AD.

Front Immunol. 2015 Sep 16;6:474. doi: 10.3389/fimmu.2015.00474. eCollection 2015. Review.

PMID:: 26441979

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Select item 2642446044.

Baseline HIV-1 resistance, virological outcomes, and emergent resistance in the SECOND-LINE trial: an exploratory analysis.

Boyd MA, Moore CL, Molina JM, Wood R, Madero JS, Wolff M, Ruxrungtham K, Losso M, Renjifo B, Teppler H, Kelleher AD, Amin J, Emery S, Cooper DA; SECOND-LINE study group.

Lancet HIV. 2015 Feb;2(2):e42-51. doi: 10.1016/S2352-3018(14)00061-7. Epub 2015 Jan 20.

PMID:: 26424460

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Select item 2642412045.

Temporal trends in prognostic markers of HIV-1 virulence and transmissibility: an observational cohort study.

Pantazis N, Porter K, Costagliola D, De Luca A, Ghosn J, Guiguet M, Johnson AM, Kelleher AD, Morrison C, Thiebaut R, Wittkop L, Touloumi G; CASCADE Collaboration in EuroCoord.

Lancet HIV. 2014 Dec;1(3):e119-26. doi: 10.1016/S2352-3018(14)00002-2. Epub 2014 Nov 18.