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Items: 5


New dosing strategies for an old antibiotic: pharmacodynamics of front-loaded regimens of colistin at simulated pharmacokinetics in patients with kidney or liver disease.

Rao GG, Ly NS, Haas CE, Garonzik S, Forrest A, Bulitta JB, Kelchlin PA, Holden PN, Nation RL, Li J, Tsuji BT.

Antimicrob Agents Chemother. 2014;58(3):1381-8. doi: 10.1128/AAC.00327-13. Epub 2013 Dec 16.


Pharmacodynamics of early, high-dose linezolid against vancomycin-resistant enterococci with elevated MICs and pre-existing genetic mutations.

Tsuji BT, Bulitta JB, Brown T, Forrest A, Kelchlin PA, Holden PN, Peloquin CA, Skerlos L, Hanna D.

J Antimicrob Chemother. 2012 Sep;67(9):2182-90. doi: 10.1093/jac/dks201. Epub 2012 Jun 8.


Front-loaded linezolid regimens result in increased killing and suppression of the accessory gene regulator system of Staphylococcus aureus.

Tsuji BT, Brown T, Parasrampuria R, Brazeau DA, Forrest A, Kelchlin PA, Holden PN, Peloquin CA, Hanna D, Bulitta JB.

Antimicrob Agents Chemother. 2012 Jul;56(7):3712-9. doi: 10.1128/AAC.05453-11. Epub 2012 Apr 23.


In vitro pharmacodynamics of novel rifamycin ABI-0043 against Staphylococcus aureus.

Tsuji BT, Yang JC, Forrest A, Kelchlin PA, Smith PF.

J Antimicrob Chemother. 2008 Jul;62(1):156-60. doi: 10.1093/jac/dkn133. Epub 2008 Apr 9.


Attenuated vancomycin bactericidal activity against Staphylococcus aureus hemB mutants expressing the small-colony-variant phenotype.

Tsuji BT, von Eiff C, Kelchlin PA, Forrest A, Smith PF.

Antimicrob Agents Chemother. 2008 Apr;52(4):1533-7. doi: 10.1128/AAC.01254-07. Epub 2008 Feb 19.

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