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Items: 17

1.

Effective mismatch repair depends on timely control of PCNA retention on DNA by the Elg1 complex.

Paul Solomon Devakumar LJ, Gaubitz C, Lundblad V, Kelch BA, Kubota T.

Nucleic Acids Res. 2019 May 22. pii: gkz441. doi: 10.1093/nar/gkz441. [Epub ahead of print]

PMID:
31114918
2.

A Hyperthermophilic Phage Decoration Protein Suggests Common Evolutionary Origin with Herpesvirus Triplex Proteins and an Anti-CRISPR Protein.

Stone NP, Hilbert BJ, Hidalgo D, Halloran KT, Lee J, Sontheimer EJ, Kelch BA.

Structure. 2018 Jul 3;26(7):936-947.e3. doi: 10.1016/j.str.2018.04.008. Epub 2018 May 17.

PMID:
29779790
3.

Substrate sequence selectivity of APOBEC3A implicates intra-DNA interactions.

Silvas TV, Hou S, Myint W, Nalivaika E, Somasundaran M, Kelch BA, Matsuo H, Kurt Yilmaz N, Schiffer CA.

Sci Rep. 2018 May 14;8(1):7511. doi: 10.1038/s41598-018-25881-z.

4.

Crystal structure of APOBEC3A bound to single-stranded DNA reveals structural basis for cytidine deamination and specificity.

Kouno T, Silvas TV, Hilbert BJ, Shandilya SMD, Bohn MF, Kelch BA, Royer WE, Somasundaran M, Kurt Yilmaz N, Matsuo H, Schiffer CA.

Nat Commun. 2017 Apr 28;8:15024. doi: 10.1038/ncomms15024.

5.

The large terminase DNA packaging motor grips DNA with its ATPase domain for cleavage by the flexible nuclease domain.

Hilbert BJ, Hayes JA, Stone NP, Xu RG, Kelch BA.

Nucleic Acids Res. 2017 Apr 7;45(6):3591-3605. doi: 10.1093/nar/gkw1356.

6.

Review: The lord of the rings: Structure and mechanism of the sliding clamp loader.

Kelch BA.

Biopolymers. 2016 Aug;105(8):532-46. doi: 10.1002/bip.22827. Review.

PMID:
26918303
7.

A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site.

Duffy CM, Hilbert BJ, Kelch BA.

J Mol Biol. 2016 Mar 27;428(6):1023-1040. doi: 10.1016/j.jmb.2015.11.029. Epub 2015 Dec 11.

PMID:
26688547
8.

Structure and mechanism of the ATPase that powers viral genome packaging.

Hilbert BJ, Hayes JA, Stone NP, Duffy CM, Sankaran B, Kelch BA.

Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):E3792-9. doi: 10.1073/pnas.1506951112. Epub 2015 Jul 6.

9.

The ssDNA Mutator APOBEC3A Is Regulated by Cooperative Dimerization.

Bohn MF, Shandilya SMD, Silvas TV, Nalivaika EA, Kouno T, Kelch BA, Ryder SP, Kurt-Yilmaz N, Somasundaran M, Schiffer CA.

Structure. 2015 May 5;23(5):903-911. doi: 10.1016/j.str.2015.03.016. Epub 2015 Apr 23.

10.

Functional modulation of a protein folding landscape via side-chain distortion.

Kelch BA, Salimi NL, Agard DA.

Proc Natl Acad Sci U S A. 2012 Jun 12;109(24):9414-9. doi: 10.1073/pnas.1119274109. Epub 2012 May 25.

11.

Clamp loader ATPases and the evolution of DNA replication machinery.

Kelch BA, Makino DL, O'Donnell M, Kuriyan J.

BMC Biol. 2012 Apr 20;10:34. doi: 10.1186/1741-7007-10-34.

12.

How a DNA polymerase clamp loader opens a sliding clamp.

Kelch BA, Makino DL, O'Donnell M, Kuriyan J.

Science. 2011 Dec 23;334(6063):1675-80. doi: 10.1126/science.1211884.

13.

The mechanism of ATP-dependent primer-template recognition by a clamp loader complex.

Simonetta KR, Kazmirski SL, Goedken ER, Cantor AJ, Kelch BA, McNally R, Seyedin SN, Makino DL, O'Donnell M, Kuriyan J.

Cell. 2009 May 15;137(4):659-71. doi: 10.1016/j.cell.2009.03.044.

14.

Mesophile versus thermophile: insights into the structural mechanisms of kinetic stability.

Kelch BA, Agard DA.

J Mol Biol. 2007 Jul 20;370(4):784-95. Epub 2007 May 10.

PMID:
17543987
15.

Structural and mechanistic exploration of acid resistance: kinetic stability facilitates evolution of extremophilic behavior.

Kelch BA, Eagen KP, Erciyas FP, Humphris EL, Thomason AR, Mitsuiki S, Agard DA.

J Mol Biol. 2007 May 4;368(3):870-83. Epub 2007 Feb 22.

PMID:
17382344
16.

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