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Items: 26


Transcriptional Profiling of the Murine Airway Response to Acute Ozone Exposure.

Tovar A, Smith GJ, Thomas JM, Crouse WL, Harkema JR, Kelada SNP.

Toxicol Sci. 2020 Jan 1;173(1):114-130. doi: 10.1093/toxsci/kfz219.


Development of a large-scale computer-controlled ozone inhalation exposure system for rodents.

Smith GJ, Walsh L, Higuchi M, Kelada SNP.

Inhal Toxicol. 2019 Feb;31(2):61-72. doi: 10.1080/08958378.2019.1597222. Epub 2019 Apr 25.


Determinants of QTL Mapping Power in the Realized Collaborative Cross.

Keele GR, Crouse WL, Kelada SNP, Valdar W.

G3 (Bethesda). 2019 May 7;9(5):1707-1727. doi: 10.1534/g3.119.400194.


Meta-analysis of airway epithelium gene expression in asthma.

Tsai YH, Parker JS, Yang IV, Kelada SNP.

Eur Respir J. 2018 May 17;51(5). pii: 1701962. doi: 10.1183/13993003.01962-2017. Print 2018 May.


Differential Regulation of Zfp30 Expression in Murine Airway Epithelia Through Altered Binding of ZFP148 to rs51434084.

Laudermilk LT, Thomas JM, Kelada SN.

G3 (Bethesda). 2018 Feb 2;8(2):687-693. doi: 10.1534/g3.117.300507.


Predicted effects of observed changes in the mRNA and microRNA transcriptome of lung neutrophils during S. pneumoniae pneumonia in mice.

Gomez JC, Dang H, Kanke M, Hagan RS, Mock JR, Kelada SNP, Sethupathy P, Doerschuk CM.

Sci Rep. 2017 Sep 12;7(1):11258. doi: 10.1038/s41598-017-11638-7.


Identification of trans Protein QTL for Secreted Airway Mucins in Mice and a Causal Role for Bpifb1.

Donoghue LJ, Livraghi-Butrico A, McFadden KM, Thomas JM, Chen G, Grubb BR, O'Neal WK, Boucher RC, Kelada SNP.

Genetics. 2017 Oct;207(2):801-812. doi: 10.1534/genetics.117.300211. Epub 2017 Aug 29.


Plethysmography Phenotype QTL in Mice Before and After Allergen Sensitization and Challenge.

Kelada SN.

G3 (Bethesda). 2016 Sep 8;6(9):2857-65. doi: 10.1534/g3.116.032912.


Identification of microRNAs associated with allergic airway disease using a genetically diverse mouse population.

Rutledge H, Baran-Gale J, de Villena FP, Chesler EJ, Churchill GA, Sethupathy P, Kelada SN.

BMC Genomics. 2015 Aug 25;16:633. doi: 10.1186/s12864-015-1732-9.


Genetic regulation of Zfp30, CXCL1, and neutrophilic inflammation in murine lung.

Rutledge H, Aylor DL, Carpenter DE, Peck BC, Chines P, Ostrowski LE, Chesler EJ, Churchill GA, de Villena FP, Kelada SN.

Genetics. 2014 Oct;198(2):735-45. doi: 10.1534/genetics.114.168138. Epub 2014 Aug 11.


Transcriptional targets of the schizophrenia risk gene MIR137.

Collins AL, Kim Y, Bloom RJ, Kelada SN, Sethupathy P, Sullivan PF.

Transl Psychiatry. 2014 Jul 1;4:e404. doi: 10.1038/tp.2014.42.


Integrative genetic analysis of allergic inflammation in the murine lung.

Kelada SN, Carpenter DE, Aylor DL, Chines P, Rutledge H, Chesler EJ, Churchill GA, Pardo-Manuel de Villena F, Schwartz DA, Collins FS.

Am J Respir Cell Mol Biol. 2014 Sep;51(3):436-45. doi: 10.1165/rcmb.2013-0501OC.


Genetic analysis of hematological parameters in incipient lines of the collaborative cross.

Kelada SN, Aylor DL, Peck BC, Ryan JF, Tavarez U, Buus RJ, Miller DR, Chesler EJ, Threadgill DW, Churchill GA, Pardo-Manuel de Villena F, Collins FS.

G3 (Bethesda). 2012 Feb;2(2):157-65. doi: 10.1534/g3.111.001776. Epub 2012 Feb 1.


Genetic analysis of complex traits in the emerging Collaborative Cross.

Aylor DL, Valdar W, Foulds-Mathes W, Buus RJ, Verdugo RA, Baric RS, Ferris MT, Frelinger JA, Heise M, Frieman MB, Gralinski LE, Bell TA, Didion JD, Hua K, Nehrenberg DL, Powell CL, Steigerwalt J, Xie Y, Kelada SN, Collins FS, Yang IV, Schwartz DA, Branstetter LA, Chesler EJ, Miller DR, Spence J, Liu EY, McMillan L, Sarkar A, Wang J, Wang W, Zhang Q, Broman KW, Korstanje R, Durrant C, Mott R, Iraqi FA, Pomp D, Threadgill D, de Villena FP, Churchill GA.

Genome Res. 2011 Aug;21(8):1213-22. doi: 10.1101/gr.111310.110. Epub 2011 Mar 15.


Strain-dependent genomic factors affect allergen-induced airway hyperresponsiveness in mice.

Kelada SN, Wilson MS, Tavarez U, Kubalanza K, Borate B, Whitehead GS, Maruoka S, Roy MG, Olive M, Carpenter DE, Brass DM, Wynn TA, Cook DN, Evans CM, Schwartz DA, Collins FS.

Am J Respir Cell Mol Biol. 2011 Oct;45(4):817-24. doi: 10.1165/rcmb.2010-0315OC. Epub 2011 Mar 4.


Neurodegenerative diseases.

Checkoway H, Lundin JI, Kelada SN.

IARC Sci Publ. 2011;(163):407-19. Review.


5' and 3' region variability in the dopamine transporter gene (SLC6A3), pesticide exposure and Parkinson's disease risk: a hypothesis-generating study.

Kelada SN, Checkoway H, Kardia SL, Carlson CS, Costa-Mallen P, Eaton DL, Firestone J, Powers KM, Swanson PD, Franklin GM, Longstreth WT Jr, Weller TS, Afsharinejad Z, Costa LG.

Hum Mol Genet. 2006 Oct 15;15(20):3055-62. Epub 2006 Sep 8.


Dopamine transporter (SLC6A3) 5' region haplotypes significantly affect transcriptional activity in vitro but are not associated with Parkinson's disease.

Kelada SN, Costa-Mallen P, Checkoway H, Carlson CS, Weller TS, Swanson PD, Franklin GM, Longstreth WT Jr, Afsharinejad Z, Costa LG.

Pharmacogenet Genomics. 2005 Sep;15(9):659-68.


Characterization of the in vitro transcriptional activity of polymorphic alleles of the human monoamine oxidase-B gene.

Costa-Mallen P, Kelada SN, Costa LG, Checkoway H.

Neurosci Lett. 2005 Jul 22-29;383(1-2):171-5. Epub 2005 Apr 19.


DNA sequence analysis of monoamine oxidase B gene coding and promoter regions in Parkinson's disease cases and unrelated controls.

Costa-Mallen P, Afsharinejad Z, Kelada SN, Costa LG, Franklin GM, Swanson PD, Longstreth WT Jr, Viernes HM, Farin FM, Smith-Weller T, Checkoway H.

Mov Disord. 2004 Jan;19(1):76-83.


The role of genetic polymorphisms in environmental health.

Kelada SN, Eaton DL, Wang SS, Rothman NR, Khoury MJ.

Environ Health Perspect. 2003 Jun;111(8):1055-64. Review.


Paraoxonase 1 promoter and coding region polymorphisms in Parkinson's disease.

Kelada SN, Costa-Mallen P, Checkoway H, Viernes HA, Farin FM, Smith-Weller T, Franklin GM, Costa LG, Longstreth WT Jr, Furlong CE, Jarvik GP, Swanson PD.

J Neurol Neurosurg Psychiatry. 2003 Apr;74(4):546-7. No abstract available.


Glutathione S-transferase M1, T1, and P1 polymorphisms and Parkinson's disease.

Kelada SN, Stapleton PL, Farin FM, Bammler TK, Eaton DL, Smith-Weller T, Franklin GM, Swanson PD, Longstreth WT Jr, Checkoway H.

Neurosci Lett. 2003 Jan 30;337(1):5-8.


Gender difference in the interaction of smoking and monoamine oxidase B intron 13 genotype in Parkinson's disease.

Kelada SN, Costa-Mallen P, Costa LG, Smith-Weller T, Franklin GM, Swanson PD, Longstreth WT Jr, Checkoway H.

Neurotoxicology. 2002 Oct;23(4-5):515-9.


Delta-aminolevulinic acid dehydratase genotype and lead toxicity: a HuGE review.

Kelada SN, Shelton E, Kaufmann RB, Khoury MJ.

Am J Epidemiol. 2001 Jul 1;154(1):1-13. Review.


The glutathione S-transferase-mu and -theta genotypes in the etiology of prostate cancer: genotype-environment interactions with smoking.

Kelada SN, Kardia SL, Walker AH, Wein AJ, Malkowicz SB, Rebbeck TR.

Cancer Epidemiol Biomarkers Prev. 2000 Dec;9(12):1329-34.

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