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Accelerated cardiomyocyte senescence contributes to late-onset doxorubicin-induced cardiotoxicity.

Mitry MA, Laurent D, Keith BL, Sira E, Eisenberg CA, Eisenberg LM, Joshi S, Gupte S, Edwards JG.

Am J Physiol Cell Physiol. 2020 Jan 8. doi: 10.1152/ajpcell.00073.2019. [Epub ahead of print]


Fructose-1,6-Bisphosphatase 2 Inhibits Sarcoma Progression by Restraining Mitochondrial Biogenesis.

Huangyang P, Li F, Lee P, Nissim I, Weljie AM, Mancuso A, Li B, Keith B, Yoon SS, Celeste Simon M.

Cell Metab. 2020 Jan 7;31(1):174-188.e7. doi: 10.1016/j.cmet.2019.10.012. Epub 2019 Nov 21.


Impairment of Electroneutral Na+Transport and Associated Down-Regulation of NHE3 Contributes to Diarrhea Following in vivo Challenge with Brachyspira spp.

Enns CB, Keith BA, Challa N, Harding JCS, Loewen ME.

Am J Physiol Gastrointest Liver Physiol. 2019 Nov 25. doi: 10.1152/ajpgi.00011.2019. [Epub ahead of print]


Optimal sequencing of enzalutamide and abiraterone acetate plus prednisone in metastatic castration-resistant prostate cancer: a multicentre, randomised, open-label, phase 2, crossover trial.

Khalaf DJ, Annala M, Taavitsainen S, Finch DL, Oja C, Vergidis J, Zulfiqar M, Sunderland K, Azad AA, Kollmannsberger CK, Eigl BJ, Noonan K, Wadhwa D, Attwell A, Keith B, Ellard SL, Le L, Gleave ME, Wyatt AW, Chi KN.

Lancet Oncol. 2019 Dec;20(12):1730-1739. doi: 10.1016/S1470-2045(19)30688-6. Epub 2019 Nov 11.


Swallowing outcomes after pediatric epiglottopexy.

Kanotra SP, Givens VB, Keith B.

Eur Arch Otorhinolaryngol. 2020 Jan;277(1):285-291. doi: 10.1007/s00405-019-05664-6. Epub 2019 Sep 24.


Von Willebrand Factor Type A domain of hCLCA1 is sufficient for U-937 macrophage activation.

Keith BA, Ching JCH, Loewen ME.

Biochem Biophys Rep. 2019 Mar 28;18:100630. doi: 10.1016/j.bbrep.2019.100630. eCollection 2019 Jul.


Acute Respiratory Illness in Rural Haiti.

Kim YY, Lew JF, Keith B, Telisma T, Nelson EJ, Brantly AC, Chavannes S, Anilis G, Yang Y, Liu M, Alam MT, Rashid MH, Morris JG Jr, Madsen Beau De Rochars VE.

Int J Infect Dis. 2019 Apr;81:176-183. doi: 10.1016/j.ijid.2019.02.003. Epub 2019 Feb 14.


Colonic epithelial miR-31 associates with the development of Crohn's phenotypes.

Keith BP, Barrow JB, Toyonaga T, Kazgan N, O'Connor MH, Shah ND, Schaner MS, Wolber EA, Trad OK, Gipson GR, Pitman WA, Kanke M, Saxena SJ, Chaumont N, Sadiq TS, Koruda MJ, Cotney PA, Allbritton N, Trembath DG, Sylvester F, Furey TS, Sethupathy P, Sheikh SZ.

JCI Insight. 2018 Oct 4;3(19). pii: 122788. doi: 10.1172/jci.insight.122788.


Letter to the Editor: An Affront to Scientific Inquiry Re: Moore, D. R. (2018) Editorial: Auditory Processing Disorder, Ear Hear, 39, 617-620.

Iliadou VV, Chermak GD, Bamiou DE, Rawool VW, Ptok M, Purdy S, Jutras B, Moncrieff D, Stokkereit Mattsson T, Ferre JM, Fox C, Grech H, Geffner D, Hedjever M, Bellis TJ, Nimatoudis I, Eleftheriadis N, Pedersen ER, Weihing J, Guillory L, Madell JR, Hurley A, Whitelaw GM, Schochat E, Spyridakou C, Sidiras C, Thai-Van H, Kostopoulou A, Veuillet E, Keith B, Mountjoy A, Koohi N, Sirimanna T, Lau C, Cone B, Kiese-Himmel C, Abramson M, Raghunathrao R, Musiek FE.

Ear Hear. 2018 Nov/Dec;39(6):1236-1242. doi: 10.1097/AUD.0000000000000644. No abstract available.


Arginase 2 Suppresses Renal Carcinoma Progression via Biosynthetic Cofactor Pyridoxal Phosphate Depletion and Increased Polyamine Toxicity.

Ochocki JD, Khare S, Hess M, Ackerman D, Qiu B, Daisak JI, Worth AJ, Lin N, Lee P, Xie H, Li B, Wubbenhorst B, Maguire TG, Nathanson KL, Alwine JC, Blair IA, Nissim I, Keith B, Simon MC.

Cell Metab. 2018 Jun 5;27(6):1263-1280.e6. doi: 10.1016/j.cmet.2018.04.009. Epub 2018 May 10.


Canadian Cancer Trials Group (CCTG) IND211: A randomized trial of pelareorep (Reolysin) in patients with previously treated advanced or metastatic non-small cell lung cancer receiving standard salvage therapy.

Bradbury PA, Morris DG, Nicholas G, Tu D, Tehfe M, Goffin JR, Shepherd FA, Gregg RW, Rothenstein J, Lee C, Kuruvilla S, Keith BD, Torri V, Blais N, Hao D, Korpanty GJ, Goss G, Melosky BL, Mates M, Leighl N, Ayoub JP, Sederias J, Feilotter H, Seymour L, Laurie SA.

Lung Cancer. 2018 Jun;120:142-148. doi: 10.1016/j.lungcan.2018.03.005. Epub 2018 Mar 9.


Impact of supraglottoplasty on parental preception of swallowing using a 10 question swallowing index.

Kanotra SP, Vaitaitis V, Hopkins H, Fletcher M, Gonsoulin CK, Keith B.

Int J Pediatr Otorhinolaryngol. 2018 Jun;109:122-126. doi: 10.1016/j.ijporl.2018.03.037. Epub 2018 Apr 6.


The Structure of Medical Intensive Care Units at Training Institutions.

Heincelman M, Duckett A, Keith B, Schreiner A, Zhang J, Kilb E, Clyburn B.

Am J Med Sci. 2018 Apr;355(4):396-401. doi: 10.1016/j.amjms.2017.08.020. Epub 2017 Sep 1.


Pancreatic cancer therapy with combined mesothelin-redirected chimeric antigen receptor T cells and cytokine-armed oncolytic adenoviruses.

Watanabe K, Luo Y, Da T, Guedan S, Ruella M, Scholler J, Keith B, Young RM, Engels B, Sorsa S, Siurala M, Havunen R, Tähtinen S, Hemminki A, June CH.

JCI Insight. 2018 Apr 5;3(7). pii: 99573. doi: 10.1172/jci.insight.99573. eCollection 2018 Apr 5.


Endoscopic Management Postcholedochoduodenostomy for Choledochal Cysts.

Shah KP, Ramachandran V, Lee FC, Keith B, Mazziotti MV, Fishman DS.

J Pediatr Gastroenterol Nutr. 2018 Aug;67(2):e36. doi: 10.1097/MPG.0000000000001928. No abstract available.


IRE1α RNase-dependent lipid homeostasis promotes survival in Myc-transformed cancers.

Xie H, Tang CH, Song JH, Mancuso A, Del Valle JR, Cao J, Xiang Y, Dang CV, Lan R, Sanchez DJ, Keith B, Hu CC, Simon MC.

J Clin Invest. 2018 Apr 2;128(4):1300-1316. doi: 10.1172/JCI95864. Epub 2018 Feb 26.


A prognostic model for stratifying clinical outcomes in chemotherapy-naive metastatic castration-resistant prostate cancer patients treated with abiraterone acetate.

Khalaf DJ, Avilés CM, Azad AA, Sunderland K, Todenhöfer T, Eigl BJ, Finch D, Le L, Atwell A, Keith B, Kollmannsberger C, Chi KN.

Can Urol Assoc J. 2018 Feb;12(2):E47-E52. doi: 10.5489/cuaj.4600. Epub 2017 Dec 1.


Enhancing CAR T cell persistence through ICOS and 4-1BB costimulation.

Guedan S, Posey AD Jr, Shaw C, Wing A, Da T, Patel PR, McGettigan SE, Casado-Medrano V, Kawalekar OU, Uribe-Herranz M, Song D, Melenhorst JJ, Lacey SF, Scholler J, Keith B, Young RM, June CH.

JCI Insight. 2018 Jan 11;3(1). pii: 96976. doi: 10.1172/jci.insight.96976. eCollection 2018 Jan 11.


Constitutive redox and phosphoproteome changes in multiple herbicide resistant Avena fatua L. are similar to those of systemic acquired resistance and systemic acquired acclimation.

Burns EE, Keith BK, Refai MY, Bothner B, Dyer WE.

J Plant Physiol. 2018 Jan;220:105-114. doi: 10.1016/j.jplph.2017.11.004. Epub 2017 Nov 20.


Augmentation of Antitumor Immunity by Human and Mouse CAR T Cells Secreting IL-18.

Hu B, Ren J, Luo Y, Keith B, Young RM, Scholler J, Zhao Y, June CH.

Cell Rep. 2017 Sep 26;20(13):3025-3033. doi: 10.1016/j.celrep.2017.09.002.


Serving people with severe mental illness who are dually eligible for Medicare and Medicaid.

Hill C, Aung KK, Ajayi T, Cheng M, Easton L, Derby K, Genser J, Keith B, Johnson P.

Healthc (Amst). 2018 Jun;6(2):139-143. doi: 10.1016/j.hjdsi.2017.07.001. Epub 2017 Aug 8. No abstract available.


Proteomic and biochemical assays of glutathione-related proteins in susceptible and multiple herbicide resistant Avena fatua L.

Burns EE, Keith BK, Refai MY, Bothner B, Dyer WE.

Pestic Biochem Physiol. 2017 Aug;140:69-78. doi: 10.1016/j.pestbp.2017.06.007. Epub 2017 Jun 9.


Case 2: Neck Pain, Neck Swelling, and Chest Pain in a 17-year-old Boy.

Osakwe O, Keith B.

Pediatr Rev. 2017 Jun;38(6):282. doi: 10.1542/pir.2015-0122. No abstract available.


Intensive herbicide use has selected for constitutively elevated levels of stress-responsive mRNAs and proteins in multiple herbicide-resistant Avena fatua L.

Keith BK, Burns EE, Bothner B, Carey CC, Mazurie AJ, Hilmer JK, Biyiklioglu S, Budak H, Dyer WE.

Pest Manag Sci. 2017 Nov;73(11):2267-2281. doi: 10.1002/ps.4605. Epub 2017 Aug 18.


Parental Sharing on the Internet: Child Privacy in the Age of Social Media and the Pediatrician's Role.

Keith BE, Steinberg S.

JAMA Pediatr. 2017 May 1;171(5):413-414. doi: 10.1001/jamapediatrics.2016.5059. No abstract available.


Long-Term, Competitive Swimming and the Association with Atrial Fibrillation.

Schreiner AD, Keith BA, Abernathy KE, Zhang J, Brzezinski WA.

Sports Med Open. 2016 Dec;2(1):42. Epub 2016 Oct 17.


Oxygen availability and metabolic adaptations.

Nakazawa MS, Keith B, Simon MC.

Nat Rev Cancer. 2016 Sep 23;16(10):663-73. doi: 10.1038/nrc.2016.84. Review.


Farmers' perception and adaptation practice to climate variability and change: a case study of the Vea catchment in Ghana.

Limantol AM, Keith BE, Azabre BA, Lennartz B.

Springerplus. 2016 Jun 22;5(1):830. doi: 10.1186/s40064-016-2433-9. eCollection 2016.


Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control Adenocarcinoma.

Posey AD Jr, Schwab RD, Boesteanu AC, Steentoft C, Mandel U, Engels B, Stone JD, Madsen TD, Schreiber K, Haines KM, Cogdill AP, Chen TJ, Song D, Scholler J, Kranz DM, Feldman MD, Young R, Keith B, Schreiber H, Clausen H, Johnson LA, June CH.

Immunity. 2016 Jun 21;44(6):1444-54. doi: 10.1016/j.immuni.2016.05.014.


Endurance swimming and increased risk of atrial fibrillation.

Schreiner AD, Keith BA, Brzezinski WA.

J Sport Health Sci. 2016 Jun;5(2):246-247. doi: 10.1016/j.jshs.2015.03.004. Epub 2015 Apr 17. No abstract available.


Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells.

Kawalekar OU, O' Connor RS, Fraietta JA, Guo L, McGettigan SE, Posey AD Jr, Patel PR, Guedan S, Scholler J, Keith B, Snyder NW, Blair IA, Milone MC, June CH.

Immunity. 2016 Mar 15;44(3):712. doi: 10.1016/j.immuni.2016.02.023. Epub 2016 Mar 15. No abstract available.


Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells.

Kawalekar OU, O'Connor RS, Fraietta JA, Guo L, McGettigan SE, Posey AD Jr, Patel PR, Guedan S, Scholler J, Keith B, Snyder NW, Blair IA, Milone MC, June CH.

Immunity. 2016 Feb 16;44(2):380-90. doi: 10.1016/j.immuni.2016.01.021. Erratum in: Immunity. 2016 Mar 15;44(3):712. Snyder, Nathaniel [corrected to Snyder, Nathaniel W]; Blair, Ian [corrected to Blair, Ian A]. Erratum in: Immunity. 2016 Mar 15;44(3):712.


A short-term transition from a high-fat diet to a normal-fat diet before pregnancy exacerbates female mouse offspring obesity.

Fu Q, Olson P, Rasmussen D, Keith B, Williamson M, Zhang KK, Xie L.

Int J Obes (Lond). 2016 Apr;40(4):564-72. doi: 10.1038/ijo.2015.236. Epub 2015 Nov 26.


Feedback circuitry between miR-218 repression and RTK activation in glioblastoma.

Mathew LK, Huangyang P, Mucaj V, Lee SS, Skuli N, Eisinger-Mathason TS, Biju K, Li B, Venneti S, Lal P, Lathia JD, Rich JN, Keith B, Simon MC.

Sci Signal. 2015 May 5;8(375):ra42. doi: 10.1126/scisignal.2005978.


HIF2α-Dependent Lipid Storage Promotes Endoplasmic Reticulum Homeostasis in Clear-Cell Renal Cell Carcinoma.

Qiu B, Ackerman D, Sanchez DJ, Li B, Ochocki JD, Grazioli A, Bobrovnikova-Marjon E, Diehl JA, Keith B, Simon MC.

Cancer Discov. 2015 Jun;5(6):652-67. doi: 10.1158/2159-8290.CD-14-1507. Epub 2015 Mar 31.


When Hodgkin comes to a head: Hodgkin central nervous system involvement.

Hathaway AR, Amadon JP, Keith BA.

Am J Med Sci. 2015 Jun;349(6):552-3. doi: 10.1097/MAJ.0000000000000437. No abstract available.


The Changing Face of Residency Education.

Clyburn EB, Duckett AA, Allen SL, Keith BA.

J S C Med Assoc. 2015 Jan;110(4):140-2. No abstract available.


Locus heterogeneity disease genes encode proteins with high interconnectivity in the human protein interaction network.

Keith BP, Robertson DL, Hentges KE.

Front Genet. 2014 Dec 9;5:434. doi: 10.3389/fgene.2014.00434. eCollection 2014.


An archaeal family-B DNA polymerase variant able to replicate past DNA damage: occurrence of replicative and translesion synthesis polymerases within the B family.

Jozwiakowski SK, Keith BJ, Gilroy L, Doherty AJ, Connolly BA.

Nucleic Acids Res. 2014 Sep;42(15):9949-63. doi: 10.1093/nar/gku683. Epub 2014 Jul 24.


Fructose-1,6-bisphosphatase opposes renal carcinoma progression.

Li B, Qiu B, Lee DS, Walton ZE, Ochocki JD, Mathew LK, Mancuso A, Gade TP, Keith B, Nissim I, Simon MC.

Nature. 2014 Sep 11;513(7517):251-5. doi: 10.1038/nature13557. Epub 2014 Jul 20.


DNA polymerase hybrids derived from the family-B enzymes of Pyrococcus furiosus and Thermococcus kodakarensis: improving performance in the polymerase chain reaction.

Elshawadfy AM, Keith BJ, Ee Ooi H, Kinsman T, Heslop P, Connolly BA.

Front Microbiol. 2014 May 27;5:224. doi: 10.3389/fmicb.2014.00224. eCollection 2014.


Human immunodeficiency virus reverse transcriptase displays dramatically higher fidelity under physiological magnesium conditions in vitro.

Achuthan V, Keith BJ, Connolly BA, DeStefano JJ.

J Virol. 2014 Aug;88(15):8514-27. doi: 10.1128/JVI.00752-14. Epub 2014 May 21. Erratum in: J Virol. 2015 Feb;89(3):1944.


Home-based administration of Sayana® Press: review and assessment of needs in low-resource settings.

Keith B, Wood S, Tifft S, Hutchings J.

Contraception. 2014 May;89(5):344-51. doi: 10.1016/j.contraception.2014.03.003. Epub 2014 Mar 12. Review.


Racial/ethnic differences in multiple diabetes outcomes in patients with type 2 diabetes in the southeastern United States.

Lynch CP, Williams JL, Reid J, Joseph R, Keith B, Egede LE.

Ethn Dis. 2014 Spring;24(2):189-94.


Is parental smoking neglect of an asthmatic child?

Keith B, Handley KB.

Virtual Mentor. 2014 Apr 1;16(4):252-6. doi: 10.1001/virtualmentor.2014.16.04.ecas3-1404. No abstract available.


Gender differences in composite control of cardiovascular risk factors among patients with type 2 diabetes.

Strom Williams JL, Lynch CP, Winchester R, Thomas L, Keith B, Egede LE.

Diabetes Technol Ther. 2014 Jul;16(7):421-7. doi: 10.1089/dia.2013.0329. Epub 2014 Apr 15.


Perceptions of home and self-injection of Sayana® Press in Ethiopia: a qualitative study.

Keith B, Wood S, Chapman C, Alemu E.

Contraception. 2014 May;89(5):379-84. doi: 10.1016/j.contraception.2013.12.010. Epub 2013 Dec 27.


Network medicine analysis of chondrocyte proteins towards new treatments of osteoarthritis.

Nacher JC, Keith B, Schwartz JM.

Proc Biol Sci. 2014 Jan 15;281(1778):20132907. doi: 10.1098/rspb.2013.2907. Print 2014 Mar 7.


miR-218 opposes a critical RTK-HIF pathway in mesenchymal glioblastoma.

Mathew LK, Skuli N, Mucaj V, Lee SS, Zinn PO, Sathyan P, Imtiyaz HZ, Zhang Z, Davuluri RV, Rao S, Venneti S, Lal P, Lathia JD, Rich JN, Keith B, Minn AJ, Simon MC.

Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):291-6. doi: 10.1073/pnas.1314341111. Epub 2013 Dec 24.


Restricted expression of miR-30c-2-3p and miR-30a-3p in clear cell renal cell carcinomas enhances HIF2α activity.

Mathew LK, Lee SS, Skuli N, Rao S, Keith B, Nathanson KL, Lal P, Simon MC.

Cancer Discov. 2014 Jan;4(1):53-60. doi: 10.1158/2159-8290.CD-13-0291. Epub 2013 Nov 4.

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