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Items: 1 to 50 of 51

1.

Dose-dependent neovascularization-promoting effect of adenovirus vector CI-1023 in a rat hindlimb ischaemic model.

Wang H, Keiser JA, Olszewski B, Brammer D, Gordon D.

Basic Clin Pharmacol Toxicol. 2004 Aug;95(2):76-80.

2.

Delayed angiogenesis in aging rats and therapeutic effect of adenoviral gene transfer of VEGF.

Wang H, Keiser JA, Olszewski B, Rosebury W, Robertson A, Kovesdi I, Gordon D.

Int J Mol Med. 2004 Apr;13(4):581-7.

PMID:
15010860
3.

Increased revascularization efficacy after administration of an adenovirus encoding VEGF(121).

Perrin LA, June JE, Rosebury W, Robertson A, Kovesdi I, Bruder JT, Kessler PD, Keiser JA, Gordon D.

Gene Ther. 2004 Mar;11(6):512-21.

PMID:
14999223
4.

Impaired angiogenesis in SHR is associated with decreased KDR and MT1-MMP expression.

Wang H, Olszewski B, Rosebury W, Wang D, Robertson A, Keiser JA.

Biochem Biophys Res Commun. 2004 Mar 5;315(2):363-8.

PMID:
14766216
5.

Rat sponge implant model: a new system for evaluating angiogenic gene transfer.

Wang H, Gordon D, Olszewski B, Song YL, Kovesdi I, Keiser JA.

Int J Mol Med. 2000 Dec;6(6):645-53.

PMID:
11078823
6.

Hepatocyte growth factor enhances MMP activity in human endothelial cells.

Wang H, Keiser JA.

Biochem Biophys Res Commun. 2000 Jun 16;272(3):900-5.

PMID:
10860849
7.

Electromagnetic guidance for catheter-based transendocardial injection: a platform for intramyocardial angiogenesis therapy. Results in normal and ischemic porcine models.

Kornowski R, Leon MB, Fuchs S, Vodovotz Y, Flynn MA, Gordon DA, Pierre A, Kovesdi I, Keiser JA, Epstein SE.

J Am Coll Cardiol. 2000 Mar 15;35(4):1031-9.

8.

Use of fluorescent microspheres to localize in vivo gene transfer injection sites.

Flynn MA, Vodovotz Y, Kornowski R, Epstein S, Gordon D, Keiser JA.

Biotechniques. 2000 Mar;28(3):470-2, 475-6.

9.

Butenolide endothelin antagonists with improved aqueous solubility.

Patt WC, Cheng XM, Repine JT, Lee C, Reisdorph BR, Massa MA, Doherty AM, Welch KM, Bryant JW, Flynn MA, Walker DM, Schroeder RL, Haleen SJ, Keiser JA.

J Med Chem. 1999 Jun 17;42(12):2162-8.

PMID:
10377221
10.

PD 142893, SB 209670, and BQ 788 selectively antagonize vascular endothelial versus vascular smooth muscle ET(B)-receptor activity in the rat.

Schroeder RL, Keiser JA, Cheng XM, Haleen SJ.

J Cardiovasc Pharmacol. 1998 Dec;32(6):935-43.

PMID:
9869499
12.

Animal model that mimics atherosclerotic plaque rupture.

Rekhter MD, Hicks GW, Brammer DW, Work CW, Kim JS, Gordon D, Keiser JA, Ryan MJ.

Circ Res. 1998 Oct 5;83(7):705-13.

PMID:
9758640
13.

Influence of lipoprotein(a) plasma concentration on neointimal growth in a monkey model of vascular injury.

Ryan MJ, Emig LL, Hicks GW, Ramharack R, Brammer DW, Gordon D, Auerbach BJ, Keiser JA.

Atherosclerosis. 1998 Jul;139(1):137-45.

PMID:
9699901
14.

Vascular remodeling in balloon injured rabbit iliac arteries.

Haarer SL, Emig LL, Keiser JA.

Basic Res Cardiol. 1998 Jun;93(3):210-7.

PMID:
9689447
15.

Vascular remodeling in balloon injured rabbit iliac arteries.

Haarer SL, Emig LL, Keiser JA.

Basic Res Cardiol. 1998 Apr;93(2):108-15. Erratum in: Basic Res Cardiol 1998 Jun;93(3):209.

PMID:
9601577
16.

Molecular characterization of rabbit CPP32 and its function in vascular smooth muscle cell apoptosis.

Wang H, Keiser JA.

Am J Physiol. 1998 Apr;274(4):H1132-40. doi: 10.1152/ajpheart.1998.274.4.H1132.

PMID:
9575916
18.

In vitro pharmacological characterization of PD 166285, a new nanomolar potent and broadly active protein tyrosine kinase inhibitor.

Panek RL, Lu GH, Klutchko SR, Batley BL, Dahring TK, Hamby JM, Hallak H, Doherty AM, Keiser JA.

J Pharmacol Exp Ther. 1997 Dec;283(3):1433-44.

PMID:
9400019
19.

Inhibition of cell growth: effects of the tyrosine kinase inhibitor CGP 53716.

Major TC, Keiser JA.

J Pharmacol Exp Ther. 1997 Oct;283(1):402-10.

PMID:
9336349
20.

PDGF receptor protein tyrosine kinase expression in the balloon-injured rat carotid artery.

Panek RL, Dahring TK, Olszewski BJ, Keiser JA.

Arterioscler Thromb Vasc Biol. 1997 Jul;17(7):1283-8.

PMID:
9261258
21.

Structure-activity relationships in a series of orally active gamma-hydroxy butenolide endothelin antagonists.

Patt WC, Edmunds JJ, Repine JT, Berryman KA, Reisdorph BR, Lee C, Plummer MS, Shahripour A, Haleen SJ, Keiser JA, Flynn MA, Welch KM, Reynolds EE, Rubin R, Tobias B, Hallak H, Doherty AM.

J Med Chem. 1997 Mar 28;40(7):1063-74.

PMID:
9089328
22.

Restenosis: is there a pharmacologic fix in the pipeline?

Keiser JA, Uprichard AC.

Adv Pharmacol. 1997;39:313-51. Review.

PMID:
9160119
23.

Localization of lipoprotein(a) in a monkey model of rapid neointimal growth.

Ryan MJ, Emig LL, Hicks GW, Ramharack R, Spahr MA, Kreick JS, Brammer DW, Chien AJ, Keiser JA.

Arterioscler Thromb Vasc Biol. 1997 Jan;17(1):181-7.

PMID:
9012654
24.

Renal response to blood pressure elevation in normal and glomerulonephritic rats.

Gabbai FB, De Nicola L, Peterson OW, Obagi S, Thomson SC, Tucker BJ, Keiser JA, Wilson CB, Blantz RC.

J Am Soc Nephrol. 1996 Dec;7(12):2590-9.

25.

Hemodynamic effects of epidermal growth factor in conscious rats and monkeys.

Keiser JA, Ryan MJ.

Proc Natl Acad Sci U S A. 1996 May 14;93(10):4957-61.

26.

Structure-activity studies of phosphorylated peptide inhibitors of the association of phosphatidylinositol 3-kinase with PDGF-beta receptor.

Ramalingam K, Eaton SR, Cody WL, Lu GH, Panek RL, Waite LA, Decker SJ, Keiser JA, Doherty AM.

Bioorg Med Chem. 1995 Sep;3(9):1263-72.

PMID:
8564419
27.

Pharmacological characterization of PD 156707, an orally active ETA receptor antagonist.

Reynolds EE, Keiser JA, Haleen SJ, Walker DM, Olszewski B, Schroeder RL, Taylor DG, Hwang O, Welch KM, Flynn MA, et al.

J Pharmacol Exp Ther. 1995 Jun;273(3):1410-7.

PMID:
7791115
28.

Role of epinephrine in TNF and IL-6 production from isolated perfused rat liver.

Liao J, Keiser JA, Scales WE, Kunkel SL, Kluger MJ.

Am J Physiol. 1995 Apr;268(4 Pt 2):R896-901.

PMID:
7733399
29.

Role of corticosterone in TNF and IL-6 production in isolated perfused rat liver.

Liao J, Keiser JA, Scales WE, Kunkel SL, Kluger MJ.

Am J Physiol. 1995 Mar;268(3 Pt 2):R699-706.

PMID:
7900913
30.

Pharmacologic characterization of CI-996, a new angiotensin receptor antagonist.

Keiser JA, Ryan MJ, Panek RL, Hodges JC, Sircar I.

J Pharmacol Exp Ther. 1995 Mar;272(3):963-9.

PMID:
7891350
31.

Structure-activity relationships of a novel series of orally active nonpeptide ETA and ETA/B endothelin receptor-selective antagonists.

Doherty AM, Patt WC, Repine J, Edmunds JJ, Berryman KA, Reisdorph BR, Walker DM, Haleen SJ, Keiser JA, Flynn MA, et al.

J Cardiovasc Pharmacol. 1995;26 Suppl 3:S358-61.

PMID:
8587414
32.

Effect of an orally active renin inhibitor Cl-992 on blood pressure in normotensive and hypertensive monkeys.

Ryan MJ, Hicks GW, Batley BL, Rapundalo ST, Patt WC, Taylor DG, Keiser JA.

J Pharmacol Exp Ther. 1994 Jan;268(1):372-9.

PMID:
8301578
33.

Effects of selective endothelin antagonists on the hemodynamic response to cyclosporin A.

Davis LS, Haleen SJ, Doherty AM, Cody WL, Keiser JA.

J Am Soc Nephrol. 1994 Jan;4(7):1448-54.

34.

ETA and ETB receptors coexist on rabbit pulmonary artery vascular smooth muscle mediating contraction.

LaDouceur DM, Flynn MA, Keiser JA, Reynolds E, Haleen SJ.

Biochem Biophys Res Commun. 1993 Oct 15;196(1):209-15.

PMID:
8216294
35.

Endothelin-1 mRNA in glomerular and epithelial cells of kidney.

Chen M, Todd-Turla K, Wang WH, Cao X, Smart A, Brosius FC, Killen PD, Keiser JA, Briggs JP, Schnermann J.

Am J Physiol. 1993 Oct;265(4 Pt 2):F542-50.

PMID:
8238383
36.

Why big endothelin-1 lacks a vasodilator response.

Haleen SJ, Davis LS, LaDouceur DM, Keiser JA.

J Cardiovasc Pharmacol. 1993;22 Suppl 8:S271-3.

PMID:
7509963
37.

Renal hemodynamic and excretory responses to PD 123319 and losartan, nonpeptide AT1 and AT2 subtype-specific angiotensin II ligands.

Keiser JA, Bjork FA, Hodges JC, Taylor DG Jr.

J Pharmacol Exp Ther. 1992 Sep;262(3):1154-60.

PMID:
1527720
38.

Induction of water diuresis by endothelin in rats.

Schnermann J, Lorenz JN, Briggs JP, Keiser JA.

Am J Physiol. 1992 Sep;263(3 Pt 2):F516-26.

PMID:
1415580
39.

Angiotensin II and renal functional reserve in rats with Goldblatt hypertension.

De Nicola L, Keiser JA, Blantz RC, Gabbai FB.

Hypertension. 1992 Jun;19(6 Pt 2):790-4.

PMID:
1592482
40.

Cyclic nucleotide phosphodiesterases in the circulatory system. Biochemical, pharmacological, and functional characteristics.

Weishaar RE, Kobylarz-Singer D, Keiser JA, Wright CD, Cornicelli J, Panek R.

Adv Second Messenger Phosphoprotein Res. 1992;25:249-69. Review. No abstract available.

PMID:
1313261
41.
42.

Thiophene systems. 9. Thienopyrimidinedione derivatives as potential antihypertensive agents.

Russell RK, Press JB, Rampulla RA, McNally JJ, Falotico R, Keiser JA, Bright DA, Tobia A.

J Med Chem. 1988 Sep;31(9):1786-93.

PMID:
2842504
43.

Hepatic extraction of renin: quantitation and characterization in the isolated perfused rat liver.

Keiser JA, Romero JC, Kost LJ, LaRusso NF.

Hepatology. 1987 Nov-Dec;7(6):1254-61.

PMID:
2824314
44.

Contribution of sympathetic neural reflexes to mineralocorticoid escape.

Romero JC, Knox FG, Opgenorth TJ, Granger JP, Keiser JA.

Fed Proc. 1985 May;44(8):2382-7. Review.

PMID:
3886427
45.

Hepatic clearance of renin after angiotensin blockade.

Keiser JA, Opgenorth TJ, Romero JC.

Am J Physiol. 1985 Jan;248(1 Pt 2):R23-8.

PMID:
3881984
46.

Clearance of renin in unanesthetized rats: effects of chronic lead exposure.

Keiser JA, Vander AJ, Germain CL.

Toxicol Appl Pharmacol. 1983 Jun 15;69(1):127-37.

47.

Effects of lead on the secretion and disappearance of renin in rabbits.

Keiser JA, Vander AJ, Germain CL.

Toxicol Appl Pharmacol. 1983 Jun 15;69(1):117-26.

48.

Noninvasive measurement of bone mineral mass in the unanesthetized rabbit.

Myers RC, Sanchez TV, Keiser JA, Mayor GH.

Lab Anim Sci. 1979 Feb;29(1):88-93.

PMID:
439854
49.

Aluminum and parathyroid hormone: a role in dialysis dementia?

Mayor GH, Keiser JA, Makdani DD.

Nephron. 1978;20(6):346-7. No abstract available.

PMID:
662053
50.

Factors affecting tissue aluminum concentration.

Mayor GH, Keiser JA, Sanchez TV, Sprague SM, Hook JB.

J Dial. 1978;2(5-6):471-81. Review.

PMID:
374433

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