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Items: 1 to 50 of 77

1.

Complete Genome Sequence of the Corallopyronin A-Producing Myxobacterium Corallococcus coralloides B035.

Bouhired S, Rupp O, Blom J, Schäberle TF, Schiefer A, Kehraus S, Pfarr K, Goesmann A, Hoerauf A, König G.

Microbiol Resour Announc. 2019 Apr 25;8(17). pii: e00050-19. doi: 10.1128/MRA.00050-19.

2.

Direct targeting of Gαq and Gα11 oncoproteins in cancer cells.

Annala S, Feng X, Shridhar N, Eryilmaz F, Patt J, Yang J, Pfeil EM, Cervantes-Villagrana RD, Inoue A, Häberlein F, Slodczyk T, Reher R, Kehraus S, Monteleone S, Schrage R, Heycke N, Rick U, Engel S, Pfeifer A, Kolb P, König G, Bünemann M, Tüting T, Vázquez-Prado J, Gutkind JS, Gaffal E, Kostenis E.

Sci Signal. 2019 Mar 19;12(573). pii: eaau5948. doi: 10.1126/scisignal.aau5948.

PMID:
30890659
3.

Peppermint and its respective active component in diets of broiler chickens: growth performance, viability, economics, meat physicochemical properties, and carcass characteristics.

Abdel-Wareth AAA, Kehraus S, Südekum KH.

Poult Sci. 2019 Mar 16. pii: pez099. doi: 10.3382/ps/pez099. [Epub ahead of print]

PMID:
30877743
4.

Biosynthetic studies of novel polyketides from the marine sponge-derived fungus Stachylidium sp. 293K04.

El Maddah F, Eguereva E, Kehraus S, König GM.

Org Biomol Chem. 2019 Mar 6;17(10):2747-2752. doi: 10.1039/c9ob00198k.

PMID:
30785154
5.

Soil Bacteria Isolated From Tunisian Arid Areas Show Promising Antimicrobial Activities Against Gram-Negatives.

Nasfi Z, Busch H, Kehraus S, Linares-Otoya L, König GM, Schäberle TF, Bachoual R.

Front Microbiol. 2018 Nov 13;9:2742. doi: 10.3389/fmicb.2018.02742. eCollection 2018.

6.

Cyclopropane-Containing Fatty Acids from the Marine Bacterium Labrenzia sp. 011 with Antimicrobial and GPR84 Activity.

Amiri Moghaddam J, Dávila-Céspedes A, Kehraus S, Crüsemann M, Köse M, Müller CE, König GM.

Mar Drugs. 2018 Oct 8;16(10). pii: E369. doi: 10.3390/md16100369.

7.

Antimicrobial Dialkylresorcins from Marine-Derived Microorganisms: Insights into Their Mode of Action and Putative Ecological Relevance.

Harms H, Klöckner A, Schrör J, Josten M, Kehraus S, Crüsemann M, Hanke W, Schneider T, Schäberle TF, König GM.

Planta Med. 2018 Dec;84(18):1363-1371. doi: 10.1055/a-0653-7451. Epub 2018 Jul 10.

PMID:
29991081
8.

Applying Molecular Networking for the Detection of Natural Sources and Analogues of the Selective Gq Protein Inhibitor FR900359.

Reher R, Kuschak M, Heycke N, Annala S, Kehraus S, Dai HF, Müller CE, Kostenis E, König GM, Crüsemann M.

J Nat Prod. 2018 Jul 27;81(7):1628-1635. doi: 10.1021/acs.jnatprod.8b00222. Epub 2018 Jun 26.

PMID:
29943987
9.

Deciphering Specificity Determinants for FR900359-Derived Gq α Inhibitors Based on Computational and Structure-Activity Studies.

Reher R, Kühl T, Annala S, Benkel T, Kaufmann D, Nubbemeyer B, Odhiambo JP, Heimer P, Bäuml CA, Kehraus S, Crüsemann M, Kostenis E, Tietze D, König GM, Imhof D.

ChemMedChem. 2018 Aug 20;13(16):1634-1643. doi: 10.1002/cmdc.201800304. Epub 2018 Jul 3.

PMID:
29873888
10.

Unveiling Concealed Functions of Endosymbiotic Bacteria Harbored in the Ascomycete Stachylidium bicolor.

Almeida C, Silva Pereira C, Gonzalez-Menendez V, Bills G, Pascual J, Sánchez-Hidalgo M, Kehraus S, Genilloud O.

Appl Environ Microbiol. 2018 Jul 17;84(15). pii: e00660-18. doi: 10.1128/AEM.00660-18. Print 2018 Aug 1.

11.

Heterologous Expression, Biosynthetic Studies, and Ecological Function of the Selective Gq-Signaling Inhibitor FR900359.

Crüsemann M, Reher R, Schamari I, Brachmann AO, Ohbayashi T, Kuschak M, Malfacini D, Seidinger A, Pinto-Carbó M, Richarz R, Reuter T, Kehraus S, Hallab A, Attwood M, Schiöth HB, Mergaert P, Kikuchi Y, Schäberle TF, Kostenis E, Wenzel D, Müller CE, Piel J, Carlier A, Eberl L, König GM.

Angew Chem Int Ed Engl. 2018 Jan 15;57(3):836-840. doi: 10.1002/anie.201707996. Epub 2017 Dec 20.

PMID:
29194875
12.

Secondary metabolome and its defensive role in the aeolidoidean Phyllodesmium longicirrum, (Gastropoda, Heterobranchia, Nudibranchia).

Bogdanov A, Hertzer C, Kehraus S, Nietzer S, Rohde S, Schupp PJ, Wägele H, König GM.

Beilstein J Org Chem. 2017 Mar 13;13:502-519. doi: 10.3762/bjoc.13.50. eCollection 2017.

13.

Biosynthetic Studies on Acetosellin and Structure Elucidation of a New Acetosellin Derivative.

Hufendiek P, Stölben SSM, Kehraus S, Merten N, Harms H, Crüsemann M, Arslan I, Gütschow M, Schneider T, König GM.

Planta Med. 2017 Aug;83(12-13):1044-1052. doi: 10.1055/s-0042-124493. Epub 2017 Jan 12.

PMID:
28081580
14.

Insights into the Biosynthetic Origin of 3-(3-Furyl)alanine in Stachylidium sp. 293 K04 Tetrapeptides.

El Maddah F, Kehraus S, Nazir M, Almeida C, König GM.

J Nat Prod. 2016 Nov 23;79(11):2838-2845. Epub 2016 Oct 27.

PMID:
27786475
15.

Endolides A and B, Vasopressin and Serotonin-Receptor Interacting N-Methylated Peptides from the Sponge-Derived Fungus Stachylidium sp.

Almeida C, El Maddah F, Kehraus S, Schnakenburg G, König GM.

Org Lett. 2016 Feb 5;18(3):528-31. doi: 10.1021/acs.orglett.5b03553. Epub 2016 Jan 15.

PMID:
26771858
16.

The experimental power of FR900359 to study Gq-regulated biological processes.

Schrage R, Schmitz AL, Gaffal E, Annala S, Kehraus S, Wenzel D, Büllesbach KM, Bald T, Inoue A, Shinjo Y, Galandrin S, Shridhar N, Hesse M, Grundmann M, Merten N, Charpentier TH, Martz M, Butcher AJ, Slodczyk T, Armando S, Effern M, Namkung Y, Jenkins L, Horn V, Stößel A, Dargatz H, Tietze D, Imhof D, Galés C, Drewke C, Müller CE, Hölzel M, Milligan G, Tobin AB, Gomeza J, Dohlman HG, Sondek J, Harden TK, Bouvier M, Laporte SA, Aoki J, Fleischmann BK, Mohr K, König GM, Tüting T, Kostenis E.

Nat Commun. 2015 Dec 14;6:10156. doi: 10.1038/ncomms10156.

17.

Defensive Diterpene from the Aeolidoidean Phyllodesmium longicirrum.

Bogdanov A, Hertzer C, Kehraus S, Nietzer S, Rohde S, Schupp PJ, Wägele H, König GM.

J Nat Prod. 2016 Mar 25;79(3):611-5. doi: 10.1021/acs.jnatprod.5b00860. Epub 2015 Dec 9.

PMID:
26649919
18.

Aβ-42 lowering agents from the marine-derived fungus Dichotomomyces cejpii.

Harms H, Kehraus S, Nesaei-Mosaferan D, Hufendieck P, Meijer L, König GM.

Steroids. 2015 Dec;104:182-8. doi: 10.1016/j.steroids.2015.09.012. Epub 2015 Oct 9.

PMID:
26440473
19.

Insights into Structure-Activity Relationships of Bacterial RNA Polymerase Inhibiting Corallopyronin Derivatives.

Schäberle TF, Schmitz A, Zocher G, Schiefer A, Kehraus S, Neu E, Roth M, Vassylyev DG, Stehle T, Bierbaum G, Hoerauf A, Pfarr K, König GM.

J Nat Prod. 2015 Oct 23;78(10):2505-9. doi: 10.1021/acs.jnatprod.5b00175. Epub 2015 Oct 2.

PMID:
26431157
20.

GPR18 Inhibiting Amauromine and the Novel Triterpene Glycoside Auxarthonoside from the Sponge-Derived Fungus Auxarthron reticulatum.

Nazir M, Harms H, Loef I, Kehraus S, El Maddah F, Arslan I, Rempel V, Müller CE, König GM.

Planta Med. 2015 Aug;81(12-13):1141-5. doi: 10.1055/s-0035-1545979. Epub 2015 May 8.

PMID:
26287693
21.

Phenalenones: insight into the biosynthesis of polyketides from the marine alga-derived fungus Coniothyrium cereale.

Nazir M, El Maddah F, Kehraus S, Egereva E, Piel J, Brachmann AO, König GM.

Org Biomol Chem. 2015 Aug 7;13(29):8071-9. doi: 10.1039/c5ob00844a. Epub 2015 Jul 2.

PMID:
26136222
22.

New bicyclo-spartinols from the marine-derived fungus Phaeosphaeria spartinae.

Elsebai MF, El Maddah F, Kehraus S, König GM.

Nat Prod Commun. 2015 Apr;10(4):637-9.

PMID:
25973497
23.

Effects of temporary intensive feed restriction on performance, nutrient digestibility and carcass criteria of growing male Californian rabbits.

Abdel-Wareth AA, Kehraus S, Ali AH, Ismail ZS, Südekum KH.

Arch Anim Nutr. 2015;69(1):69-78. doi: 10.1080/1745039X.2014.1002672. Epub 2015 Jan 14.

PMID:
25588067
24.

Defense in the aeolidoidean genus Phyllodesmium (Gastropoda).

Bogdanov A, Kehraus S, Bleidissel S, Preisfeld G, Schillo D, Piel J, Brachmann AO, Wägele H, König GM.

J Chem Ecol. 2014 Sep;40(9):1013-24. doi: 10.1007/s10886-014-0496-z. Epub 2014 Sep 23.

PMID:
25244950
25.

Indoloditerpenes from a marine-derived fungal strain of Dichotomomyces cejpii with antagonistic activity at GPR18 and cannabinoid receptors.

Harms H, Rempel V, Kehraus S, Kaiser M, Hufendiek P, Müller CE, König GM.

J Nat Prod. 2014 Mar 28;77(3):673-7. doi: 10.1021/np400850g. Epub 2014 Jan 28.

PMID:
24471526
26.

Corallorazines from the myxobacterium Corallococcus coralloides.

Schmitz A, Kehraus S, Schäberle TF, Neu E, Almeida C, Roth M, König GM.

J Nat Prod. 2014 Jan 24;77(1):159-63. doi: 10.1021/np400740u. Epub 2014 Jan 14.

PMID:
24422674
27.

Decoding signaling and function of the orphan G protein-coupled receptor GPR17 with a small-molecule agonist.

Hennen S, Wang H, Peters L, Merten N, Simon K, Spinrath A, Blättermann S, Akkari R, Schrage R, Schröder R, Schulz D, Vermeiren C, Zimmermann K, Kehraus S, Drewke C, Pfeifer A, König GM, Mohr K, Gillard M, Müller CE, Lu QR, Gomeza J, Kostenis E.

Sci Signal. 2013 Oct 22;6(298):ra93. doi: 10.1126/scisignal.2004350.

28.

Salimyxins and enhygrolides: antibiotic, sponge-related metabolites from the obligate marine myxobacterium Enhygromyxa salina.

Felder S, Kehraus S, Neu E, Bierbaum G, Schäberle TF, König GM.

Chembiochem. 2013 Jul 22;14(11):1363-71. doi: 10.1002/cbic.201300268. Epub 2013 Jun 21.

PMID:
23794290
29.

Salimabromide: unexpected chemistry from the obligate marine myxobacterium Enhygromxya salina.

Felder S, Dreisigacker S, Kehraus S, Neu E, Bierbaum G, Wright PR, Menche D, Schäberle TF, König GM.

Chemistry. 2013 Jul 8;19(28):9319-24. doi: 10.1002/chem.201301379. Epub 2013 May 22.

PMID:
23703738
30.

Caught between triterpene- and steroid-metabolism: 4α-carboxylic pregnane-derivative from the marine alga-derived fungus Phaeosphaeria spartinae.

Elsebai MF, Kehraus S, König GM.

Steroids. 2013 Sep;78(9):880-3. doi: 10.1016/j.steroids.2013.05.003. Epub 2013 May 16.

PMID:
23684924
31.

Unprecedented polyketides from a marine sponge-associated Stachylidium sp.

Almeida C, Eguereva E, Kehraus S, König GM.

J Nat Prod. 2013 Mar 22;76(3):322-6. doi: 10.1021/np300668j. Epub 2012 Dec 26.

PMID:
23268694
32.

Marilines A-C: novel phthalimidines from the sponge-derived fungus Stachylidium sp.

Almeida C, Hemberger Y, Schmitt SM, Bouhired S, Natesan L, Kehraus S, Dimas K, Gütschow M, Bringmann G, König GM.

Chemistry. 2012 Jul 9;18(28):8827-34. doi: 10.1002/chem.201103278. Epub 2012 Jun 18.

PMID:
22711513
33.

Marilones A-C, phthalides from the sponge-derived fungus Stachylidium sp.

Almeida C, Kehraus S, Prudêncio M, König GM.

Beilstein J Org Chem. 2011;7:1636-42. doi: 10.3762/bjoc.7.192. Epub 2011 Dec 5.

34.

Identification of a Potent and Selective Cannabinoid CB1 Receptor Antagonist from Auxarthron reticulatum.

Elsebai MF, Rempel V, Schnakenburg G, Kehraus S, Müller CE, König GM.

ACS Med Chem Lett. 2011 Sep 17;2(11):866-9. doi: 10.1021/ml200183z. eCollection 2011 Nov 10.

35.

HLE-inhibitory alkaloids with a polyketide skeleton from the marine-derived fungus Coniothyrium cereale.

Elsebai MF, Natesan L, Kehraus S, Mohamed IE, Schnakenburg G, Sasse F, Shaaban S, Gütschow M, König GM.

J Nat Prod. 2011 Oct 28;74(10):2282-5. doi: 10.1021/np2004227. Epub 2011 Sep 16.

PMID:
21923104
36.

Stachylines A-D from the sponge-derived fungus Stachylidium sp.

Almeida C, Part N, Bouhired S, Kehraus S, König GM.

J Nat Prod. 2011 Jan 28;74(1):21-5. doi: 10.1021/np1005345. Epub 2010 Dec 16.

37.

Mode of action of epoxyphomalins A and B and characterization of related metabolites from the marine-derived fungus Paraconiothyrium sp.

Mohamed IE, Kehraus S, Krick A, König GM, Kelter G, Maier A, Fiebig HH, Kalesse M, Malek NP, Gross H.

J Nat Prod. 2010 Dec 27;73(12):2053-6. doi: 10.1021/np100310k. Epub 2010 Nov 29.

PMID:
21114274
38.

Antimicrobial phenalenone derivatives from the marine-derived fungus Coniothyrium cereale.

Elsebai MF, Kehraus S, Lindequist U, Sasse F, Shaaban S, Gütschow M, Josten M, Sahl HG, König GM.

Org Biomol Chem. 2011 Feb 7;9(3):802-8. doi: 10.1039/c0ob00625d. Epub 2010 Nov 22.

PMID:
21103541
39.

Spartinoxide, a new enantiomer of A82775C with inhibitory activity toward HLE from the marine-derived Fungus Phaeosphaeria spartinae.

Elsebai MF, Kehraus S, Gütschow M, König GM.

Nat Prod Commun. 2010 Jul;5(7):1071-6.

PMID:
20734943
40.

Biosynthesis of the myxobacterial antibiotic corallopyronin A.

Erol O, Schäberle TF, Schmitz A, Rachid S, Gurgui C, El Omari M, Lohr F, Kehraus S, Piel J, Müller R, König GM.

Chembiochem. 2010 Jun 14;11(9):1253-65. doi: 10.1002/cbic.201000085.

PMID:
20503218
41.

Novel bisabolane sesquiterpenes from the marine-derived fungus Verticillium tenerum.

Almeida C, Elsaedi S, Kehraus S, König GM.

Nat Prod Commun. 2010 Apr;5(4):507-10.

PMID:
20433060
42.

Hydroxylated sclerosporin derivatives from the marine-derived fungus Cadophora malorum.

Almeida C, Eguereva E, Kehraus S, Siering C, König GM.

J Nat Prod. 2010 Mar 26;73(3):476-8. doi: 10.1021/np900608d.

43.

New polyketides from the marine-derived fungus Phaeosphaeria spartinae.

Elsebai MF, Kehraus S, Gütschow M, König GM.

Nat Prod Commun. 2009 Nov;4(11):1463-8.

PMID:
19967974
44.

In vitro chemopreventive potential of fucophlorethols from the brown alga Fucus vesiculosus L. by anti-oxidant activity and inhibition of selected cytochrome P450 enzymes.

Parys S, Kehraus S, Krick A, Glombitza KW, Carmeli S, Klimo K, Gerhäuser C, König GM.

Phytochemistry. 2010 Feb;71(2-3):221-9. doi: 10.1016/j.phytochem.2009.10.020. Epub 2009 Dec 1.

PMID:
19954804
45.

Epoxyphomalin A and B, prenylated polyketides with potent cytotoxicity from the marine-derived fungus Phoma sp.

Mohamed IE, Gross H, Pontius A, Kehraus S, Krick A, Kelter G, Maier A, Fiebig HH, König GM.

Org Lett. 2009 Nov 5;11(21):5014-7. doi: 10.1021/ol901996g.

PMID:
19813715
46.

Cytotoxic and HLE-inhibitory tetramic acid derivatives from marine-derived fungi.

Neumann K, Kehraus S, Gütschow M, König GM.

Nat Prod Commun. 2009 Mar;4(3):347-54.

PMID:
19413111
47.

Dietary derived sesquiterpenes from Phyllodesmium lizardensis.

Affeld S, Kehraus S, Wägele H, König GM.

J Nat Prod. 2009 Feb 27;72(2):298-300. doi: 10.1021/np800583e.

PMID:
19173621
48.

Myxotyrosides A and B, Unusual rhamnosides from Myxococcus sp.

Ohlendorf B, Lorenzen W, Kehraus S, Krick A, Bode HB, König GM.

J Nat Prod. 2009 Jan;72(1):82-6. doi: 10.1021/np8005875.

PMID:
19113894
49.

Phenylnannolones A-C: biosynthesis of new secondary metabolites from the myxobacterium Nannocystis exedens.

Ohlendorf B, Leyers S, Krick A, Kehraus S, Wiese M, König GM.

Chembiochem. 2008 Dec 15;9(18):2997-3003. doi: 10.1002/cbic.200800434.

PMID:
19040244
50.

Monodictyochromes A and B, dimeric xanthone derivatives from the marine algicolous fungus Monodictys putredinis.

Pontius A, Krick A, Mesry R, Kehraus S, Foegen SE, Müller M, Klimo K, Gerhäuser C, König GM.

J Nat Prod. 2008 Nov;71(11):1793-9. doi: 10.1021/np800392w. Epub 2008 Oct 21.

PMID:
18939864

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