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Items: 10

1.

Microflow UPLC and high-resolution MS as a sensitive and robust platform for quantitation of intact peptide hormones.

Chen Z, Alelyunas YW, Wrona MD, Kehler JR, Szapacs ME, Evans CA.

Bioanalysis. 2019 Jun;11(13):1275-1289. doi: 10.4155/bio-2019-0081. Epub 2019 Jul 12.

PMID:
31298556
2.

Toward best practices in data processing and analysis for intact biotherapeutics by MS in quantitative bioanalysis.

Kellie JF, Kehler JR, Karlinsey MZ, Summerfield SG.

Bioanalysis. 2017 Dec;9(23):1883-1893. doi: 10.4155/bio-2017-0179. Epub 2017 Nov 24.

PMID:
29171758
3.

A whole-molecule immunocapture LC-MS approach for the in vivo quantitation of biotherapeutics.

Kellie JF, Kehler JR, Mencken TJ, Snell RJ, Hottenstein CS.

Bioanalysis. 2016 Oct;8(20):2103-14. doi: 10.4155/bio-2016-0180. Epub 2016 Sep 9.

PMID:
27611496
4.

Application of high-resolution MS for development of peptide and large-molecule drug candidates.

Kellie JF, Kehler JR, Szapacs ME.

Bioanalysis. 2016 Feb;8(3):169-77. doi: 10.4155/bio.15.249. Epub 2016 Jan 22.

PMID:
26795399
5.

Comparison of the quantification of a therapeutic protein using nominal and accurate mass MS/MS.

Plumb RS, Fujimoto G, Mather J, Potts WB, Rainville PD, Ellor NJ, Evans C, Kehler JR, Szapacs ME.

Bioanalysis. 2012 Mar;4(5):605-15. doi: 10.4155/bio.12.15.

PMID:
22409557
6.

Utility of dried blood spot sampling and storage for increased stability of photosensitive compounds.

Bowen CL, Hemberger MD, Kehler JR, Evans CA.

Bioanalysis. 2010 Nov;2(11):1823-8. doi: 10.4155/bio.10.142.

PMID:
21083490
7.

Application of DBS for quantitative assessment of the peptide Exendin-4; comparison of plasma and DBS method by UHPLC-MS/MS.

Kehler JR, Bowen CL, Boram SL, Evans CA.

Bioanalysis. 2010 Aug;2(8):1461-8. doi: 10.4155/bio.10.108.

PMID:
21083346
8.

Absolute quantification of a therapeutic domain antibody using ultra-performance liquid chromatography-mass spectrometry and immunoassay.

Szapacs ME, Urbanski JJ, Kehler JR, Wilson R, Boram SL, Hottenstein CS, Citerone DR.

Bioanalysis. 2010 Sep;2(9):1597-608. doi: 10.4155/bio.10.70.

PMID:
21083288
10.

Development of an in vivo preclinical screen model to estimate absorption and first-pass hepatic extraction of xenobiotics. II. Use of ketoconazole to identify P-glycoprotein/CYP3A-limited bioavailability in the monkey.

Ward KW, Stelman GJ, Morgan JA, Zeigler KS, Azzarano LM, Kehler JR, McSurdy-Freed JE, Proksch JW, Smith BR.

Drug Metab Dispos. 2004 Feb;32(2):172-7.

PMID:
14744938

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