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Gut microbiome alteration in MORDOR I: a community-randomized trial of mass azithromycin distribution.

Doan T, Hinterwirth A, Worden L, Arzika AM, Maliki R, Abdou A, Kane S, Zhong L, Cummings SL, Sakar S, Chen C, Cook C, Lebas E, Chow ED, Nachamkin I, Porco TC, Keenan JD, Lietman TM.

Nat Med. 2019 Aug 12. doi: 10.1038/s41591-019-0533-0. [Epub ahead of print]


Zinc supplementation increases protein titer of recombinant CHO cells.

Capella Roca B, Alarcón Miguez A, Keenan J, Suda S, Barron N, O'Gorman D, Doolan P, Clynes M.

Cytotechnology. 2019 Aug 8. doi: 10.1007/s10616-019-00334-1. [Epub ahead of print]


Accuracy of computer-assisted vertical cup-to-disk ratio grading for glaucoma screening.

Snyder BM, Nam SM, Khunsongkiet P, Ausayakhun S, Leeungurasatien T, Leiter MR, Sevastopolsky A, Joye AS, Berlinberg EJ, Liu Y, Ramirez DA, Moe CA, Ausayakhun S, Stamper RL, Keenan JD.

PLoS One. 2019 Aug 8;14(8):e0220362. doi: 10.1371/journal.pone.0220362. eCollection 2019.


Detection of the Bacteroides fragilis toxin gene in sheep with and without small intestinal adenocarcinoma.

Keenan JI, Aitchison A, Pearson JF, Frizelle FA, Munday JS.

N Z Vet J. 2019 Aug 4:1-9. doi: 10.1080/00480169.2019.1651233. [Epub ahead of print]


Short-term weight gain among preschool children in rural Burkina Faso: a secondary analysis of a randomised controlled trial.

Dennis EG, Sie A, Ouermi L, Dah C, Tapsoba C, Zabre P, Bärnighausen T, O'Brien KS, Lebas E, Keenan JD, Oldenburg CE.

BMJ Open. 2019 Jul 29;9(7):e029634. doi: 10.1136/bmjopen-2019-029634.


Smartphone photography as a possible method of post-validation trachoma surveillance in resource-limited settings.

Snyder BM, Sié A, Tapsoba C, Dah C, Ouermi L, Zakane SA, Keenan JD, Oldenburg CE.

Int Health. 2019 Jul 22. pii: ihz035. doi: 10.1093/inthealth/ihz035. [Epub ahead of print]


Synergy Testing of Antiamoebic Agents for Acanthamoeba: Antagonistic Effect of Voriconazole.

Talbott M, Cevallos V, Chen MC, Chin SA, Lalitha P, Seitzman GD, Lietman TM, Keenan JD.

Cornea. 2019 Jul 10. doi: 10.1097/ICO.0000000000002055. [Epub ahead of print]


Protocolized hemostatic factor use in major thoracic aortic surgery.

Wagner MA, Wang H, Benrashid E, Keenan JE, Krishnamurthy Y, Levy JH, Welsby IJ, Hughes GC.

J Cardiovasc Surg (Torino). 2019 Jul 12. doi: 10.23736/S0021-9509.19.10819-1. [Epub ahead of print] No abstract available.


Biannual mass azithromycin distributions and malaria parasitemia in pre-school children in Niger: A cluster-randomized, placebo-controlled trial.

Arzika AM, Maliki R, Boubacar N, Kane S, Cotter SY, Lebas E, Cook C, Bailey RL, West SK, Rosenthal PJ, Porco TC, Lietman TM, Keenan JD; MORDOR Study Group.

PLoS Med. 2019 Jun 25;16(6):e1002835. doi: 10.1371/journal.pmed.1002835. eCollection 2019 Jun.


Delayed Presentation of Cholethorax Following Hepatic Microwave Ablation and Resection in a Patient With Metastatic Rectal Cancer.

Wong J, Dincer EH, Keenan JC, Cho RJ.

J Bronchology Interv Pulmonol. 2019 Jul;26(3):e40-e43. doi: 10.1097/LBR.0000000000000586. No abstract available.


Comprehensive study of nuclear receptor DNA binding provides a revised framework for understanding receptor specificity.

Penvose A, Keenan JL, Bray D, Ramlall V, Siggers T.

Nat Commun. 2019 Jun 7;10(1):2514. doi: 10.1038/s41467-019-10264-3.


Macrolide Resistance in MORDOR I - A Cluster-Randomized Trial in Niger.

Doan T, Arzika AM, Hinterwirth A, Maliki R, Zhong L, Cummings S, Sarkar S, Chen C, Porco TC, Keenan JD, Lietman TM; MORDOR Study Group.

N Engl J Med. 2019 Jun 6;380(23):2271-2273. doi: 10.1056/NEJMc1901535. No abstract available.


Longer-Term Assessment of Azithromycin for Reducing Childhood Mortality in Africa.

Keenan JD, Arzika AM, Maliki R, Boubacar N, Elh Adamou S, Moussa Ali M, Cook C, Lebas E, Lin Y, Ray KJ, O'Brien KS, Doan T, Oldenburg CE, Callahan EK, Emerson PM, Porco TC, Lietman TM.

N Engl J Med. 2019 Jun 6;380(23):2207-2214. doi: 10.1056/NEJMoa1817213.


Linear growth in preschool children treated with mass azithromycin distributions for trachoma: A cluster-randomized trial.

Keenan JD, Gebresillasie S, Stoller NE, Haile BA, Tadesse Z, Cotter SY, Ray KJ, Aiemjoy K, Porco TC, Callahan EK, Emerson PM, Lietman TM.

PLoS Negl Trop Dis. 2019 Jun 5;13(6):e0007442. doi: 10.1371/journal.pntd.0007442. eCollection 2019 Jun.


Gut resistome after oral antibiotics in preschool children in Burkina Faso: A randomized controlled trial.

Oldenburg CE, Hinterwirth A, Sié A, Coulibaly B, Ouermi L, Dah C, Tapsoba C, Cummings SL, Zhong L, Chen C, Sarkar S, Bärnighausen T, Lietman TM, Keenan JD, Doan T.

Clin Infect Dis. 2019 May 31. pii: ciz455. doi: 10.1093/cid/ciz455. [Epub ahead of print]


Propionibacterium acnes Causing Mediastinal Infection following Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration.

Janssen K, Keenan J, Cho R, Dincer E.

Case Rep Med. 2019 Apr 7;2019:3920868. doi: 10.1155/2019/3920868. eCollection 2019.


'We're passengers sailing in the same ship, but we have our own berths to sleep in': Evaluating patient and public involvement within a regional research programme: An action research project informed by Normalisation Process Theory.

Keenan J, Poland F, Boote J, Howe A, Wythe H, Varley A, Vicary P, Irvine L, Wellings A.

PLoS One. 2019 May 14;14(5):e0215953. doi: 10.1371/journal.pone.0215953. eCollection 2019.


Understanding Comorbidity Between Specific Learning Disabilities.

Willcutt EG, McGrath LM, Pennington BF, Keenan JM, DeFries JC, Olson RK, Wadsworth SJ.

New Dir Child Adolesc Dev. 2019 May;2019(165):91-109. doi: 10.1002/cad.20291. Epub 2019 May 9. Review.


Repeatability and Reproducibility of Slit Lamp, Optical Coherence Tomography, and Scheimpflug Measurements of Corneal Scars.

Das M, Menda SA, Panigrahi AK, Venkatesh Prajna N, Yen M, Tsang B, Kumar A, Rose-Nussbaumer J, Acharya NR, McCulloch CE, Lietman TM, McLeod SD, Keenan JD.

Ophthalmic Epidemiol. 2019 Aug;26(4):251-256. doi: 10.1080/09286586.2019.1600199. Epub 2019 Apr 25.


Utilization of Intra-airway Injection of Iopamidol.

Cho RJ, Keenan JC, Wong J, Dincer EH.

Ann Pharmacother. 2019 Aug;53(8):871-872. doi: 10.1177/1060028019843652. Epub 2019 Apr 11. No abstract available.


Community-level Association between Clinical Trachoma and Ocular Chlamydia Infection after MASS Azithromycin Distribution in a Mesoendemic Region of Niger.

Amza A, Kadri B, Nassirou B, Cotter SY, Stoller NE, West SK, Bailey RL, Porco TC, Keenan JD, Lietman TM, Oldenburg CE.

Ophthalmic Epidemiol. 2019 Aug;26(4):231-237. doi: 10.1080/09286586.2019.1597129. Epub 2019 Apr 8.


Visual Impairment in Fungal Versus Bacterial Corneal Ulcers 4 Years After Successful Antimicrobial Treatment.

Prajna NV, Srinivasan M, Mascarenhas J, Lalitha P, Rajaraman R, McClintic SM, O'Brien KS, Ray KJ, Acharya NR, Lietman TM, Keenan JD.

Am J Ophthalmol. 2019 Aug;204:124-129. doi: 10.1016/j.ajo.2019.03.010. Epub 2019 Mar 20.


Indirect Effect of Azithromycin Use on the Intestinal Microbiome Diversity of Untreated Children: A Randomized Trial.

Oldenburg CE, Sié A, Coulibaly B, Ouermi L, Dah C, Tapsoba C, Bärnighausen T, Lebas E, Arzika AM, Cummings S, Zhong L, Lietman TM, Keenan JD, Doan T.

Open Forum Infect Dis. 2019 Feb 6;6(3):ofz061. doi: 10.1093/ofid/ofz061. eCollection 2019 Mar.


ERCP-associated infected intrahepatic pancreatic pseudocyst.

Angsubhakorn N, Laub L, Keenan JC.

IDCases. 2019 Feb 15;15:e00507. doi: 10.1016/j.idcr.2019.e00507. eCollection 2019.


Repeated dose inhalation developmental toxicity study in rats exposed to cellulose insulation with boric acid additive.

Pleus RC, Bruce G, Klintworth H, Sullivan D, Johnson W, Rajendran N, Keenan J.

Inhal Toxicol. 2018 Nov - Dec;30(13-14):542-552. doi: 10.1080/08958378.2019.1576806. Epub 2019 Mar 4.


Impact of the Global Trachoma Mapping Project.

Cama A, Keenan JD, Dejene M, Courtright P.

Ophthalmic Epidemiol. 2018 Dec;25(sup1):1-2. doi: 10.1080/09286586.2018.1550205. No abstract available.


Copper-induced non-monotonic dose response in Caco-2 cells.

O'Doherty C, Keenan J, Horgan K, Murphy R, O'Sullivan F, Clynes M.

In Vitro Cell Dev Biol Anim. 2019 Apr;55(4):221-225. doi: 10.1007/s11626-019-00333-8. Epub 2019 Feb 23.


Circulating Truncated Alpha-1 Antitrypsin Glycoprotein in Patient Plasma Retains Anti-Inflammatory Capacity.

Reeves EP, Dunlea DM, McQuillan K, O'Dwyer CA, Carroll TP, Saldova R, Akepati PR, Wormald MR, McElvaney OJ, Shutchaidat V, Henry M, Meleady P, Keenan J, Liberti DC, Kotton DN, Rudd PM, Wilson AA, McElvaney NG.

J Immunol. 2019 Apr 15;202(8):2240-2253. doi: 10.4049/jimmunol.1801045. Epub 2019 Feb 22.


Sensitivity and specificity of computer vision classification of eyelid photographs for programmatic trachoma assessment.

Kim MC, Okada K, Ryner AM, Amza A, Tadesse Z, Cotter SY, Gaynor BD, Keenan JD, Lietman TM, Porco TC.

PLoS One. 2019 Feb 11;14(2):e0210463. doi: 10.1371/journal.pone.0210463. eCollection 2019.


Efficacy of Mass Azithromycin Distribution for Reducing Childhood Mortality Across Geographic Regions.

Porco TC, Oldenburg CE, Arzika AM, Kalua K, Mrango Z, Cook C, Lebas E, Bailey RL, West SK, Oron AP, Keenan JD, Lietman TM, For The Mordor Study Group.

Am J Trop Med Hyg. 2019 Feb 7. doi: 10.4269/ajtmh.18-1003. [Epub ahead of print]


Antibiotic Prescription Patterns among Children Younger than 5 Years in Nouna District, Burkina Faso.

Sié A, Coulibaly B, Adama S, Ouermi L, Dah C, Tapsoba C, Bärnighausen T, Kelly JD, Doan T, Lietman TM, Keenan JD, Oldenburg CE.

Am J Trop Med Hyg. 2019 May;100(5):1121-1124. doi: 10.4269/ajtmh.18-0791.


Community-level chlamydial serology for assessing trachoma elimination in trachoma-endemic Niger.

Kim JS, Oldenburg CE, Cooley G, Amza A, Kadri B, Nassirou B, Cotter SY, Stoller NE, West SK, Bailey RL, Keenan JD, Gaynor BD, Porco TC, Lietman TM, Martin DL.

PLoS Negl Trop Dis. 2019 Jan 28;13(1):e0007127. doi: 10.1371/journal.pntd.0007127. eCollection 2019 Jan.


NextPBM: a platform to study cell-specific transcription factor binding and cooperativity.

Mohaghegh N, Bray D, Keenan J, Penvose A, Andrilenas KK, Ramlall V, Siggers T.

Nucleic Acids Res. 2019 Apr 8;47(6):e31. doi: 10.1093/nar/gkz020.


Viral species richness and composition in young children with loose or watery stool in Ethiopia.

Aiemjoy K, Altan E, Aragie S, Fry DM, Phan TG, Deng X, Chanyalew M, Tadesse Z, Callahan EK, Delwart E, Keenan JD.

BMC Infect Dis. 2019 Jan 14;19(1):53. doi: 10.1186/s12879-019-3674-3.


Adjuvant Chemotherapy Improves Survival Following Resection of Locally Advanced Rectal Cancer with Pathologic Complete Response.

Turner MC, Keenan JE, Rushing CN, Gulack BC, Nussbaum DP, Benrashid E, Hyslop T, Strickler JH, Mantyh CR, Migaly J.

J Gastrointest Surg. 2019 Aug;23(8):1614-1622. doi: 10.1007/s11605-018-04079-8. Epub 2019 Jan 11.


Mass Azithromycin Distribution to Prevent Childhood Mortality: A Pooled Analysis of Cluster-Randomized Trials.

Oldenburg CE, Arzika AM, Amza A, Gebre T, Kalua K, Mrango Z, Cotter SY, West SK, Bailey RL, Emerson PM, O'Brien KS, Porco TC, Keenan JD, Lietman TM.

Am J Trop Med Hyg. 2019 Mar;100(3):691-695. doi: 10.4269/ajtmh.18-0846.


Mass Oral Azithromycin for Childhood Mortality: Timing of Death After Distribution in the MORDOR Trial.

Porco TC, Hart J, Arzika AM, Weaver J, Kalua K, Mrango Z, Cotter SY, Stoller NE, O'Brien KS, Fry DM, Vanderschelden B, Oldenburg CE, West SK, Bailey RL, Keenan JD, Lietman TM; Macrolides Oraux pour Réduire les Décès avec un Oeil sur la Résistance (MORDOR) Study Group.

Clin Infect Dis. 2019 May 30;68(12):2114-2116. doi: 10.1093/cid/ciy973.


Effect of Commonly Used Pediatric Antibiotics on Gut Microbial Diversity in Preschool Children in Burkina Faso: A Randomized Clinical Trial.

Oldenburg CE, Sié A, Coulibaly B, Ouermi L, Dah C, Tapsoba C, Bärnighausen T, Ray KJ, Zhong L, Cummings S, Lebas E, Lietman TM, Keenan JD, Doan T.

Open Forum Infect Dis. 2018 Nov 2;5(11):ofy289. doi: 10.1093/ofid/ofy289. eCollection 2018 Nov.


Acute exposure to organic and inorganic sources of copper: Differential response in intestinal cell lines.

Keenan J, O'Sullivan F, Henry M, Breen L, Doolan P, Sinkunaite I, Meleady P, Clynes M, Horgan K, Murphy R.

Food Sci Nutr. 2018 Oct 20;6(8):2499-2514. doi: 10.1002/fsn3.857. eCollection 2018 Nov.


Achievement Of Primary Stability Using 3D-CT Guided Custom Design Femoral Stems In Patients With Proximal Femoral Deformity : EBRA-FCA Analysis.

Hosny HA, Srinivasan SC, Hall MJ, Keenan J, Fekry H.

Acta Orthop Belg. 2017 Dec;83(4):617-623.


Safety of azithromycin in infants under six months of age in Niger: A community randomized trial.

Oldenburg CE, Arzika AM, Maliki R, Kane MS, Lebas E, Ray KJ, Cook C, Cotter SY, Zhou Z, West SK, Bailey R, Porco TC, Keenan JD, Lietman TM; MORDOR Study Group.

PLoS Negl Trop Dis. 2018 Nov 12;12(11):e0006950. doi: 10.1371/journal.pntd.0006950. eCollection 2018 Nov.


Risk Prediction Model for Major Adverse Outcome in Proximal Thoracic Aortic Surgery.

Wagner MA, Wang H, Benrashid E, Keenan JE, Ganapathi AM, Englum BR, Hughes GC.

Ann Thorac Surg. 2019 Mar;107(3):795-801. doi: 10.1016/j.athoracsur.2018.09.052. Epub 2018 Nov 8.


Accuracy of pinhole visual acuity at an urban Indian hospital.

Kumar RS, Rackenchath MV, Sathidevi AV, Nagaraj S, Moe CA, Stamper RL, Keenan JD.

Eye (Lond). 2019 Feb;33(2):335-337. doi: 10.1038/s41433-018-0237-6. Epub 2018 Oct 19. No abstract available.


Identifying a sufficient core group for trachoma transmission.

Lietman TM, Deiner MS, Oldenburg CE, Nash SD, Keenan JD, Porco TC.

PLoS Negl Trop Dis. 2018 Oct 8;12(10):e0006478. doi: 10.1371/journal.pntd.0006478. eCollection 2018 Oct.


Antimicrobial resistance following mass azithromycin distribution for trachoma: a systematic review.

O'Brien KS, Emerson P, Hooper PJ, Reingold AL, Dennis EG, Keenan JD, Lietman TM, Oldenburg CE.

Lancet Infect Dis. 2019 Jan;19(1):e14-e25. doi: 10.1016/S1473-3099(18)30444-4. Epub 2018 Oct 3. Review.


Early PREdiction of sepsis using leukocyte surface biomarkers: the ExPRES-sepsis cohort study.

Shankar-Hari M, Datta D, Wilson J, Assi V, Stephen J, Weir CJ, Rennie J, Antonelli J, Bateman A, Felton JM, Warner N, Judge K, Keenan J, Wang A, Burpee T, Brown AK, Lewis SM, Mare T, Roy AI, Wright J, Hulme G, Dimmick I, Gray A, Rossi AG, Simpson AJ, Conway Morris A, Walsh TS.

Intensive Care Med. 2018 Nov;44(11):1836-1848. doi: 10.1007/s00134-018-5389-0. Epub 2018 Oct 5.


Azithromycin and Childhood Mortality in Africa.

Keenan JD, Arzika AM, Lietman TM; MORDOR Study Group.

N Engl J Med. 2018 Oct 4;379(14):1383-1384. doi: 10.1056/NEJMc1808346. No abstract available.


A Smartphone-Based Tool for Rapid, Portable, and Automated Wide-Field Retinal Imaging.

Kim TN, Myers F, Reber C, Loury PJ, Loumou P, Webster D, Echanique C, Li P, Davila JR, Maamari RN, Switz NA, Keenan J, Woodward MA, Paulus YM, Margolis T, Fletcher DA.

Transl Vis Sci Technol. 2018 Oct 1;7(5):21. doi: 10.1167/tvst.7.5.21. eCollection 2018 Sep.


Implementing e-learning and e-tools for care home staff supporting residents with dementia and challenging behaviour: A process evaluation of the ResCare study using normalisation process theory.

Keenan J, Poland F, Manthorpe J, Hart C, Moniz-Cook E.

Dementia (London). 2018 Sep 30:1471301218803195. doi: 10.1177/1471301218803195. [Epub ahead of print]


Multimodal Neuromonitoring During Safe Surgical Dislocation of the Hip for Joint Preservation: Feasibility, Safety, and Intraoperative Observations.

Hesper T, Scalone B, Bittersohl B, Karlsson S, Keenan J, Hosalkar HS.

J Am Acad Orthop Surg Glob Res Rev. 2017 Oct 13;1(7):e038. doi: 10.5435/JAAOSGlobal-D-17-00038. eCollection 2017 Oct.

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