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Items: 1 to 50 of 86

1.

A unique role for clathrin light chain A in cell spreading and migration.

Tsygankova OM, Keen JH.

J Cell Sci. 2019 May 15;132(10). pii: jcs224030. doi: 10.1242/jcs.224030.

PMID:
30975920
2.

Exosome-mediated Transfer of αvβ3 Integrin from Tumorigenic to Nontumorigenic Cells Promotes a Migratory Phenotype.

Singh A, Fedele C, Lu H, Nevalainen MT, Keen JH, Languino LR.

Mol Cancer Res. 2016 Nov;14(11):1136-1146. Epub 2016 Jul 20.

3.

Integrins Influence the Size and Dynamics of Signaling Microclusters in a Pyk2-dependent Manner.

Steblyanko M, Anikeeva N, Campbell KS, Keen JH, Sykulev Y.

J Biol Chem. 2015 May 8;290(19):11833-42. doi: 10.1074/jbc.M114.614719. Epub 2015 Mar 16.

4.

Patched-1 proapoptotic activity is downregulated by modification of K1413 by the E3 ubiquitin-protein ligase Itchy homolog.

Chen XL, Chinchilla P, Fombonne J, Ho L, Guix C, Keen JH, Mehlen P, Riobo NA.

Mol Cell Biol. 2014 Oct;34(20):3855-66. doi: 10.1128/MCB.00960-14. Epub 2014 Aug 4.

5.

Clathrin light chains are required for the gyrating-clathrin recycling pathway and thereby promote cell migration.

Majeed SR, Vasudevan L, Chen CY, Luo Y, Torres JA, Evans TM, Sharkey A, Foraker AB, Wong NM, Esk C, Freeman TA, Moffett A, Keen JH, Brodsky FM.

Nat Commun. 2014 May 23;5:3891. doi: 10.1038/ncomms4891.

6.

Arf6 regulation of Gyrating-clathrin.

Luo Y, Zhan Y, Keen JH.

Traffic. 2013 Jan;14(1):97-106. doi: 10.1111/tra.12014. Epub 2012 Oct 16.

7.

GGA3 functions as a switch to promote Met receptor recycling, essential for sustained ERK and cell migration.

Parachoniak CA, Luo Y, Abella JV, Keen JH, Park M.

Dev Cell. 2011 Jun 14;20(6):751-63. doi: 10.1016/j.devcel.2011.05.007.

8.

Gyrating clathrin: highly dynamic clathrin structures involved in rapid receptor recycling.

Zhao Y, Keen JH.

Traffic. 2008 Dec;9(12):2253-64. doi: 10.1111/j.1600-0854.2008.00819.x. Epub 2008 Sep 13.

9.

Interaction of prostate specific membrane antigen with clathrin and the adaptor protein complex-2.

Goodman OB Jr, Barwe SP, Ritter B, McPherson PS, Vasko AJ, Keen JH, Nanus DM, Bander NH, Rajasekaran AK.

Int J Oncol. 2007 Nov;31(5):1199-203.

PMID:
17912448
10.

Phosphoinositide 3-kinase C2alpha links clathrin to microtubule-dependent movement.

Zhao Y, Gaidarov I, Keen JH.

J Biol Chem. 2007 Jan 12;282(2):1249-56. Epub 2006 Nov 15.

11.

Dynamics of membrane clathrin-coated structures during cytokinesis.

Warner AK, Keen JH, Wang YL.

Traffic. 2006 Feb;7(2):205-15.

12.

Individual phosphoinositide 3-kinase C2alpha domain activities independently regulate clathrin function.

Gaidarov I, Zhao Y, Keen JH.

J Biol Chem. 2005 Dec 9;280(49):40766-72. Epub 2005 Oct 7.

13.
14.
15.

The E3 ubiquitin ligase AIP4 mediates ubiquitination and sorting of the G protein-coupled receptor CXCR4.

Marchese A, Raiborg C, Santini F, Keen JH, Stenmark H, Benovic JL.

Dev Cell. 2003 Nov;5(5):709-22.

16.

A glimpse of coated vesicle creation? Well almost!

Santini F, Keen JH.

Nat Cell Biol. 2002 Oct;4(10):E230-2. Review. No abstract available.

PMID:
12360302
17.

G protein-coupled receptor/arrestin3 modulation of the endocytic machinery.

Santini F, Gaidarov I, Keen JH.

J Cell Biol. 2002 Feb 18;156(4):665-76. Epub 2002 Feb 11.

18.

The actin-binding protein Hip1R associates with clathrin during early stages of endocytosis and promotes clathrin assembly in vitro.

Engqvist-Goldstein AE, Warren RA, Kessels MM, Keen JH, Heuser J, Drubin DG.

J Cell Biol. 2001 Sep 17;154(6):1209-23.

19.
20.

Selective recruitment of arrestin-3 to clathrin coated pits upon stimulation of G protein-coupled receptors.

Santini F, Penn RB, Gagnon AW, Benovic JL, Keen JH.

J Cell Sci. 2000 Jul;113 ( Pt 13):2463-70.

21.

The class II phosphoinositide 3-kinase PI3K-C2alpha is concentrated in the trans-Golgi network and present in clathrin-coated vesicles.

Domin J, Gaidarov I, Smith ME, Keen JH, Waterfield MD.

J Biol Chem. 2000 Apr 21;275(16):11943-50.

22.

Spatial control of coated-pit dynamics in living cells.

Gaidarov I, Santini F, Warren RA, Keen JH.

Nat Cell Biol. 1999 May;1(1):1-7.

PMID:
10559856
23.
24.

Acute cholesterol depletion inhibits clathrin-coated pit budding.

Subtil A, Gaidarov I, Kobylarz K, Lampson MA, Keen JH, McGraw TE.

Proc Natl Acad Sci U S A. 1999 Jun 8;96(12):6775-80.

25.

Arrestin function in G protein-coupled receptor endocytosis requires phosphoinositide binding.

Gaidarov I, Krupnick JG, Falck JR, Benovic JL, Keen JH.

EMBO J. 1999 Feb 15;18(4):871-81.

26.

George Frederic Still--registrar, Great Ormond Street Children's Hospital.

Keen JH.

Br J Rheumatol. 1998 Nov;37(11):1247. No abstract available.

PMID:
9851280
27.
28.

Modulation of the arrestin-clathrin interaction in cells. Characterization of beta-arrestin dominant-negative mutants.

Krupnick JG, Santini F, Gagnon AW, Keen JH, Benovic JL.

J Biol Chem. 1997 Dec 19;272(51):32507-12.

29.

Role of arrestins in G-protein-coupled receptor endocytosis.

Goodman OB Jr, Krupnick JG, Santini F, Gurevich VV, Penn RB, Gagnon AW, Keen JH, Benovic JL.

Adv Pharmacol. 1998;42:429-33. No abstract available.

PMID:
9327931
30.

Arrestin/clathrin interaction. Localization of the arrestin binding locus to the clathrin terminal domain.

Goodman OB Jr, Krupnick JG, Gurevich VV, Benovic JL, Keen JH.

J Biol Chem. 1997 Jun 6;272(23):15017-22.

31.

Arrestin/clathrin interaction. Localization of the clathrin binding domain of nonvisual arrestins to the carboxy terminus.

Krupnick JG, Goodman OB Jr, Keen JH, Benovic JL.

J Biol Chem. 1997 Jun 6;272(23):15011-6.

32.

Mapping of the molecular determinants involved in the interaction between eps15 and AP-2.

Iannolo G, Salcini AE, Gaidarov I, Goodman OB Jr, Baulida J, Carpenter G, Pelicci PG, Di Fiore PP, Keen JH.

Cancer Res. 1997 Jan 15;57(2):240-5.

33.

Beta-arrestin acts as a clathrin adaptor in endocytosis of the beta2-adrenergic receptor.

Goodman OB Jr, Krupnick JG, Santini F, Gurevich VV, Penn RB, Gagnon AW, Keen JH, Benovic JL.

Nature. 1996 Oct 3;383(6599):447-50.

PMID:
8837779
34.

A functional phosphatidylinositol 3,4,5-trisphosphate/phosphoinositide binding domain in the clathrin adaptor AP-2 alpha subunit. Implications for the endocytic pathway.

Gaidarov I, Chen Q, Falck JR, Reddy KK, Keen JH.

J Biol Chem. 1996 Aug 23;271(34):20922-9. Erratum in: J Biol Chem 1996 Oct 25;271(43):27188.

35.

Reversing life-threatening cardiac glycoside intoxication with digoxin immune Fab.

Keen JH, Huppert P.

J Emerg Nurs. 1996 Apr;22(2):136-7. No abstract available.

PMID:
8716303
36.

Thrombin stimulates wortmannin-inhibitable phosphoinositide 3-kinase and membrane blebbing in CHRF-288 cells.

Vemuri GS, Zhang J, Huang R, Keen JH, Rittenhouse SE.

Biochem J. 1996 Mar 15;314 ( Pt 3):805-10.

38.

Chromosome localization of human genes for clathrin adaptor polypeptides AP2 beta and AP50 and the clathrin-binding protein, VCP.

Druck T, Gu Y, Prabhala G, Cannizzaro LA, Park SH, Huebner K, Keen JH.

Genomics. 1995 Nov 1;30(1):94-7.

PMID:
8595912
39.

The alpha chain of the AP-2 adaptor is a clathrin binding subunit.

Goodman OB Jr, Keen JH.

J Biol Chem. 1995 Oct 6;270(40):23768-73.

40.

Slow down.

Keen JH.

J Emerg Nurs. 1995 Aug;21(4):323-6. No abstract available.

PMID:
7658630
41.

Intravenous magnesium sulfate for acute asthma.

Keen JH.

J Emerg Nurs. 1995 Feb;21(1):44-6. No abstract available.

PMID:
7776580
42.

Giving medications to different age groups.

Keen JH.

J Emerg Nurs. 1994 Dec;20(6):549-51. No abstract available.

PMID:
7745911
43.

Clathrin assembly protein AP-3 is phosphorylated and glycosylated on the 50-kDa structural domain.

Murphy JE, Hanover JA, Froehlich M, DuBois G, Keen JH.

J Biol Chem. 1994 Aug 19;269(33):21346-52.

44.

Valosin-containing protein, VCP, is a ubiquitous clathrin-binding protein.

Pleasure IT, Black MM, Keen JH.

Nature. 1993 Sep 30;365(6445):459-62.

PMID:
8413590
45.
46.

Inositol hexakisphosphate receptor identified as the clathrin assembly protein AP-2.

Voglmaier SM, Keen JH, Murphy JE, Ferris CD, Prestwich GD, Snyder SH, Theibert AB.

Biochem Biophys Res Commun. 1992 Aug 31;187(1):158-63.

PMID:
1325787
47.
48.

Interaction of assembly protein AP-2 and its isolated subunits with clathrin.

Prasad K, Keen JH.

Biochemistry. 1991 Jun 4;30(22):5590-7.

PMID:
2036430
49.

Stable clathrin: uncoating protein (hsc70) complexes in intact neurons and their axonal transport.

Black MM, Chestnut MH, Pleasure IT, Keen JH.

J Neurosci. 1991 May;11(5):1163-72.

50.

Clathrin domains involved in recognition by assembly protein AP-2.

Keen JH, Beck KA, Kirchhausen T, Jarrett T.

J Biol Chem. 1991 Apr 25;266(12):7950-6.

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