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Items: 1 to 50 of 439

1.

Improvement in cardiovascular biomarkers sustained at 4 years following an initial treat-to-target strategy in early rheumatoid arthritis.

Mortimer I, Bissell LA, Hensor EMA, Kozera L, Mackie SL, Burska AN, Nam JL, Keen H, Villeneuve E, Donica H, Buch MH, Conaghan PG, Emery P, Morgan AW, Andrews J.

Rheumatology (Oxford). 2019 Sep 1;58(9):1684-1686. doi: 10.1093/rheumatology/kez114. No abstract available.

2.

Infection Rates Before and After Diagnosis of IgA Vasculitis in Childhood: A Population-wide Study Using Non-exposed Matched Controls.

Nossent JC, Raymond W, Keen H, Preen DB, Inderjeeth CA.

J Rheumatol. 2019 Jun 15. pii: jrheum.190110. doi: 10.3899/jrheum.190110. [Epub ahead of print]

PMID:
31203216
3.

Musculoskeletal Ultrasound in Systemic Lupus Erythematosus: Systematic Literature Review by the Lupus Task Force of the OMERACT Ultrasound Working Group.

Wong PC, Lee G, Sedie AD, Hanova P, Inanc N, Jousse-Joulin S, Ohrndorf S, Stoenoiu MS, Keen HI, Terslev L, D'Agostino MA, Bruyn GA.

J Rheumatol. 2019 Oct;46(10):1379-1387. doi: 10.3899/jrheum.181087. Epub 2019 Jun 15.

PMID:
31203213
4.

Conditional deletion of smooth muscle Cullin-3 causes severe progressive hypertension.

Agbor LN, Nair AR, Wu J, Lu KT, Davis DR, Keen HL, Quelle FW, McCormick JA, Singer JD, Sigmund CD.

JCI Insight. 2019 Jun 11;5. pii: 129793. doi: 10.1172/jci.insight.129793.

5.

Development of semiquantitative ultrasound scoring system to assess cartilage in rheumatoid arthritis.

Mandl P, Studenic P, Filippucci E, Bachta A, Backhaus M, Bong D, Bruyn GAW, Collado P, Damjanov N, Dejaco C, Delle-Sedie A, De Miguel E, Duftner C, Gessl I, Gutierrez M, Hammer HB, Hernandez-Diaz C, Iagnocco A, Ikeda K, Kane D, Keen H, Kelly S, Kővári E, Möller I, Møller-Dohn U, Naredo E, Nieto JC, Pineda C, Platzer A, Rodriguez A, Schmidt WA, Supp G, Szkudlarek M, Terslev L, Thiele R, Wakefield RJ, Windschall D, D'Agostino MA, Balint PV; OMERACT Ultrasound Cartilage Task Force Group.

Rheumatology (Oxford). 2019 Oct 1;58(10):1802-1811. doi: 10.1093/rheumatology/kez153.

PMID:
31034077
6.

RhoBTB1 protects against hypertension and arterial stiffness by restraining phosphodiesterase 5 activity.

Mukohda M, Fang S, Wu J, Agbor LN, Nair AR, Ibeawuchi SC, Hu C, Liu X, Lu KT, Guo DF, Davis DR, Keen HL, Quelle FW, Sigmund CD.

J Clin Invest. 2019 Mar 21;129(6):2318-2332. doi: 10.1172/JCI123462.

7.

The OMERACT Stepwise Approach to Select and Develop Imaging Outcome Measurement Instruments: The Musculoskeletal Ultrasound Example.

Terslev L, Naredo E, Keen HI, Bruyn GAW, Iagnocco A, Wakefield RJ, Conaghan PG, Maxwell LJ, Beaton DE, Boers M, D'Agostino MA.

J Rheumatol. 2019 Oct;46(10):1394-1400. doi: 10.3899/jrheum.181158. Epub 2019 Mar 15.

PMID:
30877208
8.

OMERACT Definitions for Ultrasonographic Pathologies and Elementary Lesions of Rheumatic Disorders 15 Years On.

Bruyn GA, Iagnocco A, Naredo E, Balint PV, Gutierrez M, Hammer HB, Collado P, Filippou G, Schmidt WA, Jousse-Joulin S, Mandl P, Conaghan PG, Wakefield RJ, Keen HI, Terslev L, D'Agostino MA; OMERACT Ultrasound Working Group.

J Rheumatol. 2019 Oct;46(10):1388-1393. doi: 10.3899/jrheum.181095. Epub 2019 Feb 1.

PMID:
30709946
9.

Imaging in the diagnosis of idiopathic inflammatory myopathies; indications and utility.

Paramalingam S, Counsel P, Mastaglia FL, Keen H, Needham M.

Expert Rev Neurother. 2019 Feb;19(2):173-184. doi: 10.1080/14737175.2019.1572507. Epub 2019 Feb 7.

PMID:
30661408
10.

Pregnancy outcomes in women with a history of immunoglobulin A vasculitis.

Nossent J, Raymond W, Keen H, Inderjeeth C, Preen D.

Rheumatology (Oxford). 2019 May 1;58(5):884-888. doi: 10.1093/rheumatology/key408.

PMID:
30590848
11.

Vaccination for hepatitis B virus in an Australian pre-biologic population with rheumatoid arthritis.

Ihdayhid D, Edelman J, Keen HI.

Clin Exp Rheumatol. 2019 Jan-Feb;37(1):164. Epub 2018 Sep 20. No abstract available.

12.

Arginine vasopressin infusion is sufficient to model clinical features of preeclampsia in mice.

Sandgren JA, Deng G, Linggonegoro DW, Scroggins SM, Perschbacher KJ, Nair AR, Nishimura TE, Zhang SY, Agbor LN, Wu J, Keen HL, Naber MC, Pearson NA, Zimmerman KA, Weiss RM, Bowdler NC, Usachev YM, Santillan DA, Potthoff MJ, Pierce GL, Gibson-Corley KN, Sigmund CD, Santillan MK, Grobe JL.

JCI Insight. 2018 Oct 4;3(19). pii: 99403. doi: 10.1172/jci.insight.99403.

14.

Hospitalisation rates and characteristics for adult and childhood immunoglobulin A vasculitis in Western Australia.

Nossent J, Raymond W, Keen H, Inderjeeth C, Preen DB.

Intern Med J. 2019 Apr;49(4):475-481. doi: 10.1111/imj.14065.

PMID:
30091295
15.

Does anti-tumour necrosis factor alpha therapy exert a long-term structural benefit in hand osteoarthritis?

Roman-Blas JA, Keen H, Herrero-Beaumont G.

Rheumatology (Oxford). 2018 Nov 1;57(11):1879-1880. doi: 10.1093/rheumatology/key210. No abstract available.

PMID:
30053251
16.

Long-Term Vegetation Dynamics in a Megadiverse Hotspot: The Ice-Age Record of a Pre-montane Forest of Central Ecuador.

Montoya E, Keen HF, Luzuriaga CX, Gosling WD.

Front Plant Sci. 2018 Feb 20;9:196. doi: 10.3389/fpls.2018.00196. eCollection 2018.

17.

Ultrasonographic assessment of joint pathology in type 2 diabetes and hyperuricemia: The Fremantle Diabetes Study Phase II.

Keen HI, Davis WA, Latkovic E, Drinkwater JJ, Nossent J, Davis TME.

J Diabetes Complications. 2018 Apr;32(4):400-405. doi: 10.1016/j.jdiacomp.2017.12.015. Epub 2018 Jan 5.

PMID:
29483015
18.

Clinimetrics of ultrasound pathologies in osteoarthritis: systematic literature review and meta-analysis.

Oo WM, Linklater JM, Daniel M, Saarakkala S, Samuels J, Conaghan PG, Keen HI, Deveza LA, Hunter DJ.

Osteoarthritis Cartilage. 2018 May;26(5):601-611. doi: 10.1016/j.joca.2018.01.021. Epub 2018 Feb 7.

19.

Correction to: The relationship between endogenous thymidine concentrations and [18F]FLT uptake in a range of preclinical tumour models.

Heinzmann K, Honess DJ, Lewis DY, Smith DM, Cawthorne C, Keen H, Heskamp S, Schelhaas S, Witney TH, Soloviev D, Williams KJ, Jacobs AH, Aboagye EO, Griffiths JR, Brindle KM.

EJNMMI Res. 2017 Dec 15;7(1):99. doi: 10.1186/s13550-017-0349-1.

20.

EVOLVE: The Australian Rheumatology Association's 'top five' list of investigations and interventions doctors and patients should question.

Morrisroe K, Nakayama A, Soon J, Arnold M, Barnsley L, Barrett C, Brooks PM, Hall S, Hanrahan P, Hissaria P, Jones G, Katikireddi VS, Keen H, Laurent R, Nikpour M, Poulsen K, Robinson P, Soden M, Wood N, Cook N, Hill C, Buchbinder R.

Intern Med J. 2018 Feb;48(2):135-143. doi: 10.1111/imj.13654.

PMID:
29080286
21.

3'-Deoxy-3'-[18F]Fluorothymidine Uptake Is Related to Thymidine Phosphorylase Expression in Various Experimental Tumor Models.

Schelhaas S, Heinzmann K, Honess DJ, Smith DM, Keen H, Heskamp S, Witney TH, Besret L, Doblas S, Griffiths JR, Aboagye EO, Jacobs AH.

Mol Imaging Biol. 2018 Apr;20(2):194-199. doi: 10.1007/s11307-017-1125-3.

22.

Hypertension-Causing Mutation in Peroxisome Proliferator-Activated Receptor γ Impairs Nuclear Export of Nuclear Factor-κB p65 in Vascular Smooth Muscle.

Mukohda M, Lu KT, Guo DF, Wu J, Keen HL, Liu X, Ketsawatsomkron P, Stump M, Rahmouni K, Quelle FW, Sigmund CD.

Hypertension. 2017 Jul;70(1):174-182. doi: 10.1161/HYPERTENSIONAHA.117.09276. Epub 2017 May 15.

23.

Retinol-binding protein 7 is an endothelium-specific PPARγ cofactor mediating an antioxidant response through adiponectin.

Hu C, Keen HL, Lu KT, Liu X, Wu J, Davis DR, Ibeawuchi SC, Vogel S, Quelle FW, Sigmund CD.

JCI Insight. 2017 Mar 23;2(6):e91738. doi: 10.1172/jci.insight.91738.

24.

The OMERACT Ultrasound Group: A Report from the OMERACT 2016 Meeting and Perspectives.

Terslev L, Iagnocco A, Bruyn GAW, Naredo E, Vojinovic J, Collado P, Damjanov N, Filer A, Filippou G, Finzel S, Gandjbakhch F, Ikeda K, Keen HI, Kortekaas MC, Magni-Manzoni S, Ohrndorf S, Pineda C, Ravagnani V, Richards B, Sahbudin I, Schmidt WA, Siddle HJ, Stoenoiu MS, Szkudlarek M, Tzaribachev N, D'Agostino MA; OMERACT Ultrasound Group.

J Rheumatol. 2017 Nov;44(11):1740-1743. doi: 10.3899/jrheum.161240. Epub 2017 Feb 1.

PMID:
28148700
25.

Microarray Analysis of Hypertension.

Keen HL, Sigmund CD.

Methods Mol Biol. 2017;1527:41-52. doi: 10.1007/978-1-4939-6625-7_3. Review.

PMID:
28116705
26.

Cullin-3 mutation causes arterial stiffness and hypertension through a vascular smooth muscle mechanism.

Agbor LN, Ibeawuchi SC, Hu C, Wu J, Davis DR, Keen HL, Quelle FW, Sigmund CD.

JCI Insight. 2016 Nov 17;1(19):e91015. doi: 10.1172/jci.insight.91015.

27.

Improvement in insulin resistance is greater when infliximab is added to methotrexate during intensive treatment of early rheumatoid arthritis-results from the IDEA study.

Bissell LA, Hensor EM, Kozera L, Mackie SL, Burska AN, Nam JL, Keen H, Villeneuve E, Donica H, Buch MH, Conaghan PG, Andrews J, Emery P, Morgan AW.

Rheumatology (Oxford). 2016 Dec;55(12):2181-2190. Epub 2016 Sep 16.

28.

The relationship between endogenous thymidine concentrations and [(18)F]FLT uptake in a range of preclinical tumour models.

Heinzmann K, Honess DJ, Lewis DY, Smith DM, Cawthorne C, Keen H, Heskamp S, Schelhaas S, Witney TH, Soloviev D, Williams KJ, Jacobs AH, Aboagye EO, Griffiths JR, Brindle KM.

EJNMMI Res. 2016 Dec;6(1):63. doi: 10.1186/s13550-016-0218-3. Epub 2016 Aug 11. Erratum in: EJNMMI Res. 2017 Dec 15;7(1):99.

29.

Suppression of Resting Metabolism by the Angiotensin AT2 Receptor.

Littlejohn NK, Keen HL, Weidemann BJ, Claflin KE, Tobin KV, Markan KR, Park S, Naber MC, Gourronc FA, Pearson NA, Liu X, Morgan DA, Klingelhutz AJ, Potthoff MJ, Rahmouni K, Sigmund CD, Grobe JL.

Cell Rep. 2016 Aug 9;16(6):1548-1560. doi: 10.1016/j.celrep.2016.07.003. Epub 2016 Jul 28.

30.

Estrogen Receptor α Is Required for Maintaining Baseline Renin Expression.

Lu KT, Keen HL, Weatherford ET, Sequeira-Lopez ML, Gomez RA, Sigmund CD.

Hypertension. 2016 May;67(5):992-9. doi: 10.1161/HYPERTENSIONAHA.115.07082. Epub 2016 Feb 29.

31.

Fibrotic Aortic Valve Stenosis in Hypercholesterolemic/Hypertensive Mice.

Chu Y, Lund DD, Doshi H, Keen HL, Knudtson KL, Funk ND, Shao JQ, Cheng J, Hajj GP, Zimmerman KA, Davis MK, Brooks RM, Chapleau MW, Sigmund CD, Weiss RM, Heistad DD.

Arterioscler Thromb Vasc Biol. 2016 Mar;36(3):466-74. doi: 10.1161/ATVBAHA.115.306912. Epub 2016 Jan 14.

32.

Prevalence and associations of gout and hyperuricaemia: results from an Australian population-based study.

Ting K, Gill TK, Keen H, Tucker GR, Hill CL.

Intern Med J. 2016 May;46(5):566-73. doi: 10.1111/imj.13006.

PMID:
26765205
33.

Protective Role for Tissue Inhibitor of Metalloproteinase-4, a Novel Peroxisome Proliferator-Activated Receptor-γ Target Gene, in Smooth Muscle in Deoxycorticosterone Acetate-Salt Hypertension.

Ketsawatsomkron P, Keen HL, Davis DR, Lu KT, Stump M, De Silva TM, Hilzendeger AM, Grobe JL, Faraci FM, Sigmund CD.

Hypertension. 2016 Jan;67(1):214-22. doi: 10.1161/HYPERTENSIONAHA.115.06391. Epub 2015 Nov 23.

34.

Imaging as a potential outcome measure in gout studies: A systematic literature review.

Durcan L, Grainger R, Keen HI, Taylor WJ, Dalbeth N.

Semin Arthritis Rheum. 2016 Apr;45(5):570-9. doi: 10.1016/j.semarthrit.2015.09.008. Review.

PMID:
26522139
35.

Assessing Elementary Lesions in Gout by Ultrasound: Results of an OMERACT Patient-based Agreement and Reliability Exercise.

Terslev L, Gutierrez M, Christensen R, Balint PV, Bruyn GA, Delle Sedie A, Filippucci E, Garrido J, Hammer HB, Iagnocco A, Kane D, Kaeley GS, Keen H, Mandl P, Naredo E, Pineda C, Schicke B, Thiele R, D'Agostino MA, Schmidt WA; OMERACT US Gout Task Force.

J Rheumatol. 2015 Nov;42(11):2149-54. doi: 10.3899/jrheum.150366. Epub 2015 Oct 15. Erratum in: J Rheumatol. 2017 Jan;44(1):130.

36.

Ultrasound as an Outcome Measure in Gout. A Validation Process by the OMERACT Ultrasound Working Group.

Terslev L, Gutierrez M, Schmidt WA, Keen HI, Filippucci E, Kane D, Thiele R, Kaeley G, Balint P, Mandl P, Delle Sedie A, Hammer HB, Christensen R, Möller I, Pineda C, Kissin E, Bruyn GA, Iagnocco A, Naredo E, D'Agostino MA; OMERACT Ultrasound Working Group.

J Rheumatol. 2015 Nov;42(11):2177-81. doi: 10.3899/jrheum.141294. Epub 2015 Sep 1. Review.

37.

International Consensus for ultrasound lesions in gout: results of Delphi process and web-reliability exercise.

Gutierrez M, Schmidt WA, Thiele RG, Keen HI, Kaeley GS, Naredo E, Iagnocco A, Bruyn GA, Balint PV, Filippucci E, Mandl P, Kane D, Pineda C, Delle Sedie A, Hammer HB, Christensen R, D'Agostino MA, Terslev L; OMERACT Ultrasound Gout Task Force group.

Rheumatology (Oxford). 2015 Oct;54(10):1797-805. doi: 10.1093/rheumatology/kev112. Epub 2015 May 13.

38.

Ultrasound assessment of response to intra-articular therapy in osteoarthritis of the knee.

Keen HI, Hensor EM, Wakefield RJ, Mease PJ, Bingham CO 3rd, Conaghan PG.

Rheumatology (Oxford). 2015 Aug;54(8):1385-91. doi: 10.1093/rheumatology/keu529. Epub 2015 Feb 16.

PMID:
25691769
39.

Endothelial PPAR-γ protects against vascular thrombosis by downregulating P-selectin expression.

Jin H, Gebska MA, Blokhin IO, Wilson KM, Ketsawatsomkron P, Chauhan AK, Keen HL, Sigmund CD, Lentz SR.

Arterioscler Thromb Vasc Biol. 2015 Apr;35(4):838-44. doi: 10.1161/ATVBAHA.115.305378. Epub 2015 Feb 12.

40.

Imaging as an Outcome Measure in Gout Studies: Report from the OMERACT Gout Working Group.

Grainger R, Dalbeth N, Keen H, Durcan L, Lawrence Edwards N, Perez-Ruiz F, Diaz-Torne C, Singh JA, Khanna D, Simon LS, Taylor WJ.

J Rheumatol. 2015 Dec;42(12):2460-4. doi: 10.3899/jrheum.141164. Epub 2015 Feb 1. Review.

41.

Optimising ultrasonography in rheumatology.

Keen HI, Wakefield R, Conaghan PG.

Clin Exp Rheumatol. 2014 Sep-Oct;32(5 Suppl 85):S-13-6. Epub 2014 Oct 30. Review.

PMID:
25365083
42.

Imaging in gout: A review of the recent developments.

Chowalloor PV, Siew TK, Keen HI.

Ther Adv Musculoskelet Dis. 2014 Aug;6(4):131-43. doi: 10.1177/1759720X14542960. Review.

43.

Role of vascular smooth muscle PPARγ in regulating AT1 receptor signaling and angiotensin II-dependent hypertension.

Carrillo-Sepulveda MA, Keen HL, Davis DR, Grobe JL, Sigmund CD.

PLoS One. 2014 Aug 14;9(8):e103786. doi: 10.1371/journal.pone.0103786. eCollection 2014.

44.

Statin myopathy: the fly in the ointment for the prevention of cardiovascular disease in the 21st century?

Keen HI, Krishnarajah J, Bates TR, Watts GF.

Expert Opin Drug Saf. 2014 Sep;13(9):1227-39. doi: 10.1517/14740338.2014.937422. Epub 2014 Jul 12. Review.

PMID:
25017015
45.

The concomitants of raised blood sugar: studies in newly-detected hyperglycaemics: II. Urinary albumin excretion, blood pressure and their relation to blood sugar levels.

Keen H, Chlouverakis C, Fuller J, Jarrett RJ.

Int J Epidemiol. 2014 Feb;43(1):11-5. doi: 10.1093/ije/dyt257. Epub 2013 Dec 30.

PMID:
24381008
46.

Examining changes in [18 F]FDG and [18 F]FLT uptake in U87-MG glioma xenografts as early response biomarkers to treatment with the dual mTOR1/2 inhibitor AZD8055.

Keen HG, Ricketts SA, Maynard J, Logie A, Odedra R, Shannon AM, Wedge SR, Guichard SM.

Mol Imaging Biol. 2014 Jun;16(3):421-30. doi: 10.1007/s11307-013-0705-0.

PMID:
24249640
47.

Validation of a novel cognitive bias task based on difference in quantity of reinforcement for assessing environmental enrichment.

Keen HA, Nelson OL, Robbins CT, Evans M, Shepherdson DJ, Newberry RC.

Anim Cogn. 2014 May;17(3):529-41. doi: 10.1007/s10071-013-0684-1. Epub 2013 Sep 18.

PMID:
24045850
48.

A systematic review of ultrasonography as an outcome measure of skin involvement in systemic sclerosis.

Ch'ng SS, Roddy J, Keen HI.

Int J Rheum Dis. 2013 Jun;16(3):264-72. doi: 10.1111/1756-185X.12106. Review.

PMID:
23981746
49.

Remission induction comparing infliximab and high-dose intravenous steroid, followed by treat-to-target: a double-blind, randomised, controlled trial in new-onset, treatment-naive, rheumatoid arthritis (the IDEA study).

Nam JL, Villeneuve E, Hensor EM, Conaghan PG, Keen HI, Buch MH, Gough AK, Green MJ, Helliwell PS, Keenan AM, Morgan AW, Quinn M, Reece R, van der Heijde DM, Wakefield RJ, Emery P.

Ann Rheum Dis. 2014 Jan;73(1):75-85. doi: 10.1136/annrheumdis-2013-203440. Epub 2013 Aug 2.

PMID:
23912798
50.

Elucidating functional context within microarray data by integrated transcription factor-focused gene-interaction and regulatory network analysis.

Werner T, Dombrowski SM, Zgheib C, Zouein FA, Keen HL, Kurdi M, Booz GW.

Eur Cytokine Netw. 2013 Jun;24(2):75-90. doi: 10.1684/ecn.2013.0336.

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