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Characterization of the bacterial microbiome in first-pass meconium using propidium monoazide (PMA) to exclude nonviable bacterial DNA.

Stinson LF, Keelan JA, Payne MS.

Lett Appl Microbiol. 2019 Jan 23. doi: 10.1111/lam.13119. [Epub ahead of print]


Murine exposure to gold nanoparticles during early pregnancy promotes abortion by inhibiting ectodermal differentiation.

Yang H, Du L, Wu G, Wu Z, Keelan JA.

Mol Med. 2018 Dec 3;24(1):62. doi: 10.1186/s10020-018-0061-2.


Identification and removal of contaminating microbial DNA from PCR reagents: impact on low-biomass microbiome analyses.

Stinson LF, Keelan JA, Payne MS.

Lett Appl Microbiol. 2019 Jan;68(1):2-8. doi: 10.1111/lam.13091. Epub 2018 Nov 23.


The Relationship Between Pregnancy Exposure to Antidepressant and Atypical Antipsychotic Medications and Placental Weight and Birth Weight Ratio: A Retrospective Cohort Study.

Frayne J, Nguyen T, Hauck Y, Liira H, Keelan JA.

J Clin Psychopharmacol. 2018 Dec;38(6):563-569. doi: 10.1097/JCP.0000000000000964.


Relationship between umbilical cord sex hormone binding globulin, sex steroids, and age at menarche: a prospective cohort study.

Hickey M, Lawson LP, Marino JL, Keelan JA, Hart R.

Fertil Steril. 2018 Oct;110(5):965-973. doi: 10.1016/j.fertnstert.2018.06.008.


Intracellular speciation of gold nanorods alters the conformational dynamics of genomic DNA.

Ho D, Kretzmann JA, Norret M, Toshniwal P, Veder JP, Jiang H, Guagliardo P, Munshi AM, Chawla R, Evans CW, Clemons TD, Nguyen M, Kretzmann AL, Blythe AJ, Saunders M, Archer M, Fitzgerald M, Keelan JA, Bond CS, Kilburn MR, Hurley LH, Smith NM, Iyer KS.

Nat Nanotechnol. 2018 Dec;13(12):1148-1153. doi: 10.1038/s41565-018-0272-2. Epub 2018 Oct 8.


User-Driven Comments on a Facebook Advertisement Recruiting Canadian Parents in a Study on Immunization: Content Analysis.

Tustin JL, Crowcroft NS, Gesink D, Johnson I, Keelan J, Lachapelle B.

JMIR Public Health Surveill. 2018 Sep 20;4(3):e10090. doi: 10.2196/10090.


Antenatal IL-1-dependent inflammation persists postnatally and causes retinal and sub-retinal vasculopathy in progeny.

Beaudry-Richard A, Nadeau-Vallée M, Prairie É, Maurice N, Heckel É, Nezhady M, Pundir S, Madaan A, Boudreault A, Hou X, Quiniou C, Sierra EM, Beaulac A, Lodygensky G, Robertson SA, Keelan J, Adams-Waldorf K, Olson DM, Rivera JC, Lubell WD, Joyal JS, Bouchard JF, Chemtob S.

Sci Rep. 2018 Aug 8;8(1):11875. doi: 10.1038/s41598-018-30087-4.


The Possible Impact of Antenatal Exposure to Ubiquitous Phthalates Upon Male Reproductive Function at 20 Years of Age.

Hart RJ, Frederiksen H, Doherty DA, Keelan JA, Skakkebaek NE, Minaee NS, McLachlan R, Newnham JP, Dickinson JE, Pennell CE, Norman RJ, Main KM.

Front Endocrinol (Lausanne). 2018 Jun 4;9:288. doi: 10.3389/fendo.2018.00288. eCollection 2018.


A Critical Review of the Bacterial Baptism Hypothesis and the Impact of Cesarean Delivery on the Infant Microbiome.

Stinson LF, Payne MS, Keelan JA.

Front Med (Lausanne). 2018 May 4;5:135. doi: 10.3389/fmed.2018.00135. eCollection 2018. Review.


Comparison of Meconium DNA Extraction Methods for Use in Microbiome Studies.

Stinson LF, Keelan JA, Payne MS.

Front Microbiol. 2018 Feb 20;9:270. doi: 10.3389/fmicb.2018.00270. eCollection 2018.


Toll-like Receptor-4: A New Target for Preterm Labour Pharmacotherapies?

Robertson SA, Wahid HH, Chin PY, Hutchinson MR, Moldenhauer LM, Keelan JA.

Curr Pharm Des. 2018;24(9):960-973. doi: 10.2174/1381612824666180130122450.


Internet Exposure Associated With Canadian Parents' Perception of Risk on Childhood Immunization: Cross-Sectional Study.

Tustin JL, Crowcroft NS, Gesink D, Johnson I, Keelan J.

JMIR Public Health Surveill. 2018 Jan 19;4(1):e7. doi: 10.2196/publichealth.8921.


Problems with precaution: the transfusion medicine experience.

Wilson K, Atkinson KM, Fergusson DA, Brown A, Forster A, Murphy MSQ, Tinmouth AT, Keelan J.

J Risk Res. 2018;2017:1-13. doi: 10.1080/13669877.2017.1351478. Epub 2017 Jul 29.


Intrauterine inflammatory activation, functional progesterone withdrawal, and the timing of term and preterm birth.

Keelan JA.

J Reprod Immunol. 2018 Feb;125:89-99. doi: 10.1016/j.jri.2017.12.004. Epub 2017 Dec 22. Review.


The impact of antenatal Bisphenol A exposure on male reproductive function at 20-22 years of age.

Hart RJ, Doherty DA, Keelan JA, Minaee NS, Thorstensen EB, Dickinson JE, Pennell CE, Newnham JP, McLachlan R, Norman RJ, Handelsman DJ.

Reprod Biomed Online. 2018 Mar;36(3):340-347. doi: 10.1016/j.rbmo.2017.11.009. Epub 2017 Dec 19.


Maternal circulating adipokine profile and insulin resistance in women at high risk of developing gestational diabetes mellitus.

Guelfi KJ, Ong MJ, Li S, Wallman KE, Doherty DA, Fournier PA, Newnham JP, Keelan JA.

Metabolism. 2017 Oct;75:54-60. doi: 10.1016/j.metabol.2017.08.003. Epub 2017 Aug 24.


Recent advances in the prevention of preterm birth.

Keelan JA, Newnham JP.

F1000Res. 2017 Jul 18;6. pii: F1000 Faculty Rev-1139. doi: 10.12688/f1000research.11385.1. eCollection 2017. Review.


Facebook Recruitment of Vaccine-Hesitant Canadian Parents: Cross-Sectional Study.

Tustin JL, Crowcroft NS, Gesink D, Johnson I, Keelan J, Lachapelle B.

JMIR Public Health Surveill. 2017 Jul 24;3(3):e47. doi: 10.2196/publichealth.6870.


Maternal-placental-fetal biodistribution of multimodal polymeric nanoparticles in a pregnant rat model in mid and late gestation.

Ho D, Leong JW, Crew RC, Norret M, House MJ, Mark PJ, Waddell BJ, Iyer KS, Keelan JA.

Sci Rep. 2017 Jun 6;7(1):2866. doi: 10.1038/s41598-017-03128-7.


Cord blood androgen measurements: the importance of assay validation.

Keelan JA, Hickey M, Hollier LP.

Hum Reprod. 2017 Jun 1;32(6):1360. doi: 10.1093/humrep/dex075. No abstract available.


Applying Precision Public Health to Prevent Preterm Birth.

Newnham JP, Kemp MW, White SW, Arrese CA, Hart RJ, Keelan JA.

Front Public Health. 2017 Apr 4;5:66. doi: 10.3389/fpubh.2017.00066. eCollection 2017. Review.


Progesterone to prevent preterm birth: the studies are getting better, but there is still room for improvement.

Chung CM, van Zijl M, Keelan JA, Mol BW.

BJOG. 2017 Jun;124(7):1016. doi: 10.1111/1471-0528.14648. No abstract available.


Umbilical cord androgens and estrogens in relation to verbal and nonverbal abilities at age 10 in the general population.

Jamnadass ES, Keelan JA, Russell-Smith SN, Hickey M, Maybery MT, Whitehouse AJ.

PLoS One. 2017 Mar 9;12(3):e0173493. doi: 10.1371/journal.pone.0173493. eCollection 2017.


Umbilical cord blood androgen levels and ASD-related phenotypes at 12 and 36 months in an enriched risk cohort study.

Park BY, Lee BK, Burstyn I, Tabb LP, Keelan JA, Whitehouse AJO, Croen LA, Fallin MD, Hertz-Picciotto I, Montgomery O, Newschaffer CJ.

Mol Autism. 2017 Jan 31;8:3. doi: 10.1186/s13229-017-0118-z. eCollection 2017.


Planting the seed: Origins, composition, and postnatal health significance of the fetal gastrointestinal microbiota.

Stinson LF, Payne MS, Keelan JA.

Crit Rev Microbiol. 2017 May;43(3):352-369. doi: 10.1080/1040841X.2016.1211088. Epub 2016 Dec 8. Review.


Reducing preterm birth by a statewide multifaceted program: an implementation study.

Newnham JP, White SW, Meharry S, Lee HS, Pedretti MK, Arrese CA, Keelan JA, Kemp MW, Dickinson JE, Doherty DA.

Am J Obstet Gynecol. 2017 May;216(5):434-442. doi: 10.1016/j.ajog.2016.11.1037. Epub 2016 Nov 25.


Preclinical evaluation of drugs to block inflammation-driven preterm birth.

Ireland DJ, Nathan EA, Li S, Charles AK, Stinson LF, Kemp MW, Newnham JP, Keelan JA.

Innate Immun. 2017 Jan;23(1):20-33. doi: 10.1177/1753425916672313. Epub 2016 Nov 30.


Ureaplasma parvum genotype, combined vaginal colonisation with Candida albicans, and spontaneous preterm birth in an Australian cohort of pregnant women.

Payne MS, Ireland DJ, Watts R, Nathan EA, Furfaro LL, Kemp MW, Keelan JA, Newnham JP.

BMC Pregnancy Childbirth. 2016 Oct 18;16(1):312.


Structural and morphologic differences in human oocytes after in vitro maturation compared with standard in vitro fertilization.

Walls ML, Hart R, Keelan JA, Ryan JP.

Fertil Steril. 2016 Nov;106(6):1392-1398.e5. doi: 10.1016/j.fertnstert.2016.08.014. Epub 2016 Aug 24.


Editorial: Advances in the Prevention and Treatment of Inflammation-Associated Preterm Birth.

Keelan JA, Newnham JP.

Front Immunol. 2016 Jun 30;7:264. doi: 10.3389/fimmu.2016.00264. eCollection 2016. No abstract available.


Early Life Events Predict Adult Testicular Function; Data Derived From the Western Australian (Raine) Birth Cohort.

Hart RJ, Doherty DA, Keelan JA, McLachlan R, Skakkebaek NE, Norman RJ, Dickinson JE, Pennell CE, Newnham JP, Hickey M, Handelsman DJ.

J Clin Endocrinol Metab. 2016 Sep;101(9):3333-44. doi: 10.1210/jc.2016-1646. Epub 2016 Jun 24.


The pregnant women as a drug orphan: a global survey of registered clinical trials of pharmacological interventions in pregnancy.

Scaffidi J, Mol BW, Keelan JA.

BJOG. 2017 Jan;124(1):132-140. doi: 10.1111/1471-0528.14151. Epub 2016 Jun 14.


T cell cytokine responses to stimulation with Ureaplasma parvum in pregnancy.

Friedland YD, Lee-Pullen TF, Nathan EA, Watts R, Keelan JA, Payne MS, Ireland DJ.

J Reprod Immunol. 2016 Aug;116:93-7. doi: 10.1016/j.jri.2016.03.002. Epub 2016 Mar 17.


IFPA meeting 2015 workshop report III: nanomedicine applications and exosome biology, xenobiotics and endocrine disruptors and pregnancy, and lipid.

Albrecht C, Caniggia I, Clifton V, Göhner C, Harris L, Hemmings D, Jawerbaum A, Johnstone E, Jones H, Keelan J, Lewis R, Mitchell M, Murthi P, Powell T, Saffery R, Smith R, Vaillancourt C, Wadsack C, Salomon C.

Placenta. 2016 Dec;48 Suppl 1:S12-S16. doi: 10.1016/j.placenta.2016.01.003. Epub 2016 Jan 6.


A New, Potent, and Placenta-Permeable Macrolide Antibiotic, Solithromycin, for the Prevention and Treatment of Bacterial Infections in Pregnancy.

Keelan JA, Payne MS, Kemp MW, Ireland DJ, Newnham JP.

Front Immunol. 2016 Apr 1;7:111. doi: 10.3389/fimmu.2016.00111. eCollection 2016. Review.


Simulated annealing approach to vascular structure with application to the coronary arteries.

Keelan J, Chung EM, Hague JP.

R Soc Open Sci. 2016 Feb 10;3(2):150431. doi: 10.1098/rsos.150431. eCollection 2016 Feb.


Vaginal microbiota during pregnancy: Pathways of risk of preterm delivery in the absence of intrauterine infection?

Keelan JA, Payne MS.

Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):E6414. doi: 10.1073/pnas.1517346112. Epub 2015 Oct 29. No abstract available.


Testicular function in a birth cohort of young men.

Hart RJ, Doherty DA, McLachlan RI, Walls ML, Keelan JA, Dickinson JE, Skakkebaek NE, Norman RJ, Handelsman DJ.

Hum Reprod. 2015 Dec;30(12):2713-24. doi: 10.1093/humrep/dev244. Epub 2015 Sep 25.


Prenatal testosterone exposure is related to sexually dimorphic facial morphology in adulthood.

Whitehouse AJ, Gilani SZ, Shafait F, Mian A, Tan DW, Maybery MT, Keelan JA, Hart R, Handelsman DJ, Goonawardene M, Eastwood P.

Proc Biol Sci. 2015 Oct 7;282(1816):20151351. doi: 10.1098/rspb.2015.1351.


Therapeutic and safety considerations of nanoparticle-mediated drug delivery in pregnancy.

Keelan JA, Leong JW, Ho D, Iyer KS.

Nanomedicine (Lond). 2015 Jul;10(14):2229-47. doi: 10.2217/nnm.15.48. Review.


In vitro activity of solithromycin and its metabolites, CEM-214 and N-acetyl-CEM-101, against 100 clinical Ureaplasma spp. isolates compared with azithromycin.

Furfaro LL, Spiller OB, Keelan JA, Payne MS.

Int J Antimicrob Agents. 2015 Sep;46(3):319-24. doi: 10.1016/j.ijantimicag.2015.04.015. Epub 2015 Jun 19.


Changes in inflammatory mediators in gingival crevicular fluid following periodontal disease treatment in pregnancy: relationship to adverse pregnancy outcome.

Penova-Veselinovic B, Keelan JA, Wang CA, Newnham JP, Pennell CE.

J Reprod Immunol. 2015 Nov;112:1-10. doi: 10.1016/j.jri.2015.05.002. Epub 2015 May 27.


The perinatal androgen to estrogen ratio and autistic-like traits in the general population: a longitudinal pregnancy cohort study.

Jamnadass ES, Keelan JA, Hollier LP, Hickey M, Maybery MT, Whitehouse AJ.

J Neurodev Disord. 2015;7(1):17. doi: 10.1186/s11689-015-9114-9. Epub 2015 Jun 7.


In vitro maturation is associated with increased early embryo arrest without impairing morphokinetic development of useable embryos progressing to blastocysts.

Walls ML, Ryan JP, Keelan JA, Hart R.

Hum Reprod. 2015 Aug;30(8):1842-9. doi: 10.1093/humrep/dev125. Epub 2015 Jun 3.


Drugs to block cytokine signaling for the prevention and treatment of inflammation-induced preterm birth.

Ng PY, Ireland DJ, Keelan JA.

Front Immunol. 2015 Apr 20;6:166. doi: 10.3389/fimmu.2015.00166. eCollection 2015. Review.


Size distribution of air bubbles entering the brain during cardiac surgery.

Chung EM, Banahan C, Patel N, Janus J, Marshall D, Horsfield MA, Rousseau C, Keelan J, Evans DH, Hague JP.

PLoS One. 2015 Apr 2;10(4):e0122166. doi: 10.1371/journal.pone.0122166. eCollection 2015.


Decreased STAT3 in human idiopathic fetal growth restriction contributes to trophoblast dysfunction.

Borg AJ, Yong HE, Lappas M, Degrelle SA, Keogh RJ, Da Silva-Costa F, Fournier T, Abumaree M, Keelan JA, Kalionis B, Murthi P.

Reproduction. 2015 May;149(5):523-32. doi: 10.1530/REP-14-0622. Epub 2015 Feb 23.


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