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Reliability and Validity of SymTrak, a Multi-Domain Tool for Monitoring Symptoms of Older Adults with Multiple Chronic Conditions.

Monahan PO, Kroenke K, Callahan CM, Bakas T, Harrawood A, Lofton P, Frye D, Draucker C, Stump T, Saliba D, Galvin JE, Keegan A, Austrom MG, Boustani M.

J Gen Intern Med. 2019 Jun;34(6):908-914. doi: 10.1007/s11606-018-4780-4. Epub 2019 Apr 18.


Development and Feasibility of SymTrak, aMulti-domain Tool for Monitoring Symptoms of Older Adults in Primary Care.

Monahan PO, Kroenke K, Callahan CM, Bakas T, Harrawood A, Lofton P, Frye D, Draucker C, Stump T, Saliba D, Galvin JE, Keegan A, Austrom MG, Boustani M.

J Gen Intern Med. 2019 Jun;34(6):915-922. doi: 10.1007/s11606-018-4772-4. Epub 2019 Mar 25.


Chlorine inactivation of coxsackievirus B5 in recycled water destined for non-potable reuse.

Wati S, Robinson BS, Mieog J, Blackbeard J, Keegan AR.

J Water Health. 2019 Feb;17(1):124-136. doi: 10.2166/wh.2018.393.


Impact of clinical sample handling and processing on ultra-low level measurements of plasma cytokines.

Cohen L, Keegan A, Melanson SEF, Walt DR.

Clin Biochem. 2019 Mar;65:38-44. doi: 10.1016/j.clinbiochem.2019.01.001. Epub 2019 Jan 8.


Misinterpretation of blood group and antibody screen leading to serious errors in RhD immunoglobulin administration: A report on first two years of data from Serious Transfusion Incident Reporting program.

Akers C, Savoia H, Kane S, Crispin P, Keegan A, Wood E, Glazebrook B, Bielby L, Davis AK.

Aust N Z J Obstet Gynaecol. 2019 Feb;59(1):161-164. doi: 10.1111/ajo.12889. Epub 2018 Sep 5.


Oxaliplatin disrupts pathological features of glioma cells and associated macrophages independent of apoptosis induction.

Roberts NB, Alqazzaz A, Hwang JR, Qi X, Keegan AD, Kim AJ, Winkles JA, Woodworth GF.

J Neurooncol. 2018 Dec;140(3):497-507. doi: 10.1007/s11060-018-2979-1. Epub 2018 Aug 21.


Development of a Commercial Reference Laboratory Elective Rotation for Residents in Clinical Pathology.

Lewandrowski K, Keegan A, Makarenko V, Maryamchak E, Mata DA, Palte MJ, Rudolf JW, Safdar N, Schmidt RJ, Stuart L, Xiong Y, Rao L, Melanson SEF, Michael Snyder L.

Am J Clin Pathol. 2018 Oct 24;150(6):485-490. doi: 10.1093/ajcp/aqy070.


CD8+ T cells promote cytokine responses to stress.

Clark SM, Song C, Li X, Keegan AD, Tonelli LH.

Cytokine. 2019 Jan;113:256-264. doi: 10.1016/j.cyto.2018.07.015. Epub 2018 Jul 19.


IL-4 and IL-13 Receptor Signaling From 4PS to Insulin Receptor Substrate 2: There and Back Again, a Historical View.

Keegan AD, Zamorano J, Keselman A, Heller NM.

Front Immunol. 2018 May 15;9:1037. doi: 10.3389/fimmu.2018.01037. eCollection 2018. Review.


High-Throughput Screening of a Luciferase Reporter of Gene Silencing on the Inactive X Chromosome.

Keegan A, Plath K, Damoiseaux R.

Methods Mol Biol. 2018;1755:75-87. doi: 10.1007/978-1-4939-7724-6_6.


Flow cytometric minimal residual disease assessment of peripheral blood in acute lymphoblastic leukaemia patients has potential for early detection of relapsed extramedullary disease.

Keegan A, Charest K, Schmidt R, Briggs D, Deangelo DJ, Li B, Morgan EA, Pozdnyakova O.

J Clin Pathol. 2018 Jul;71(7):653-658. doi: 10.1136/jclinpath-2017-204828. Epub 2018 Mar 27.


Plasma cytokine IL-6 levels and subjective cognitive decline: preliminary findings.

Keegan AP, Paris D, Luis CA, Abdullah L, Ait-Ghezala G, Beaulieu-Abdelahad D, Pryor M, Chaykin J, Crynen G, Crawford F, Mullan M.

Int J Geriatr Psychiatry. 2018 Feb;33(2):358-363. doi: 10.1002/gps.4752. Epub 2017 Jun 22.


Virus removal by ultrafiltration: Understanding long-term performance change by application of Bayesian analysis.

Carvajal G, Branch A, Sisson SA, Roser DJ, van den Akker B, Monis P, Reeve P, Keegan A, Regel R, Khan SJ.

Water Res. 2017 Oct 1;122:269-279. doi: 10.1016/j.watres.2017.05.057. Epub 2017 May 30.


Increased Plasma Beta-Secretase 1 May Predict Conversion to Alzheimer's Disease Dementia in Individuals With Mild Cognitive Impairment.

Shen Y, Wang H, Sun Q, Yao H, Keegan AP, Mullan M, Wilson J, Lista S, Leyhe T, Laske C, Rujescu D, Levey A, Wallin A, Blennow K, Li R, Hampel H.

Biol Psychiatry. 2018 Mar 1;83(5):447-455. doi: 10.1016/j.biopsych.2017.02.007. Epub 2017 Mar 27.


APOE ε4 specific imbalance of arachidonic acid and docosahexaenoic acid in serum phospholipids identifies individuals with preclinical Mild Cognitive Impairment/Alzheimer's Disease.

Abdullah L, Evans JE, Emmerich T, Crynen G, Shackleton B, Keegan AP, Luis C, Tai L, LaDu MJ, Mullan M, Crawford F, Bachmeier C.

Aging (Albany NY). 2017 Mar 23;9(3):964-985. doi: 10.18632/aging.101203.


Lymphocytic esophagitis: Report of three cases and review of the literature.

Jideh B, Keegan A, Weltman M.

World J Clin Cases. 2016 Dec 16;4(12):413-418. doi: 10.12998/wjcc.v4.i12.413.


Bayesian belief network modelling of chlorine disinfection for human pathogenic viruses in municipal wastewater.

Carvajal G, Roser DJ, Sisson SA, Keegan A, Khan SJ.

Water Res. 2017 Feb 1;109:144-154. doi: 10.1016/j.watres.2016.11.008. Epub 2016 Nov 3.


A novel method for assaying human regulatory T cell direct suppression of B cell effector function.

Weingartner E, Courneya JP, Keegan A, Golding A.

J Immunol Methods. 2017 Feb;441:1-7. doi: 10.1016/j.jim.2016.11.004. Epub 2016 Nov 13.


The adaptor protein insulin receptor substrate 2 inhibits alternative macrophage activation and allergic lung inflammation.

Dasgupta P, Dorsey NJ, Li J, Qi X, Smith EP, Yamaji-Kegan K, Keegan AD.

Sci Signal. 2016 Jun 21;9(433):ra63. doi: 10.1126/scisignal.aad6724.


Enhanced allergic responsiveness after early childhood infection with respiratory viruses: Are long-lived alternatively activated macrophages the missing link?

Keegan AD, Shirey KA, Bagdure D, Blanco J, Viscardi RM, Vogel SN.

Pathog Dis. 2016 Jul;74(5). pii: ftw047. doi: 10.1093/femspd/ftw047. Epub 2016 May 12.


Expansion of brain T cells in homeostatic conditions in lymphopenic Rag2(-/-) mice.

Song C, Nicholson JD, Clark SM, Li X, Keegan AD, Tonelli LH.

Brain Behav Immun. 2016 Oct;57:161-172. doi: 10.1016/j.bbi.2016.03.017. Epub 2016 Mar 21.


Sustained benefits of autologous serum eye drops on self-reported ocular symptoms and vision-related quality of life in Australian patients with dry eye and corneal epithelial defects.

Mondy P, Brama T, Fisher J, Gemelli CN, Chee K, Keegan A, Waller D.

Transfus Apher Sci. 2015 Dec;53(3):404-11. doi: 10.1016/j.transci.2015.11.011. Epub 2015 Nov 25. Review.


Neither classical nor alternative macrophage activation is required for Pneumocystis clearance during immune reconstitution inflammatory syndrome.

Zhang ZQ, Wang J, Hoy Z, Keegan A, Bhagwat S, Gigliotti F, Wright TW.

Infect Immun. 2015 Dec;83(12):4594-603. doi: 10.1128/IAI.00763-15. Epub 2015 Sep 14.


Modelling pathogen log10 reduction values achieved by activated sludge treatment using naïve and semi naïve Bayes network models.

Carvajal G, Roser DJ, Sisson SA, Keegan A, Khan SJ.

Water Res. 2015 Nov 15;85:304-15. doi: 10.1016/j.watres.2015.08.035. Epub 2015 Aug 21.


IL-4 and IL-13: from "supe" to nuts.

Keegan AD.

Cytokine. 2015 Sep;75(1):1-2. doi: 10.1016/j.cyto.2015.06.001. Epub 2015 Jul 11. No abstract available.


The presence of opportunistic pathogens, Legionella spp., L. pneumophila and Mycobacterium avium complex, in South Australian reuse water distribution pipelines.

Whiley H, Keegan A, Fallowfield H, Bentham R.

J Water Health. 2015 Jun;13(2):553-61. doi: 10.2166/wh.2014.317.


Inhibition of CD23-mediated IgE transcytosis suppresses the initiation and development of allergic airway inflammation.

Palaniyandi S, Liu X, Periasamy S, Ma A, Tang J, Jenkins M, Tuo W, Song W, Keegan AD, Conrad DH, Zhu X.

Mucosal Immunol. 2015 Nov;8(6):1262-74. doi: 10.1038/mi.2015.16. Epub 2015 Mar 18.


Uncertainties associated with assessing the public health risk from Legionella.

Whiley H, Keegan A, Fallowfield H, Ross K.

Front Microbiol. 2014 Sep 24;5:501. doi: 10.3389/fmicb.2014.00501. eCollection 2014. Review.


Detection of Legionella, L. pneumophila and Mycobacterium avium complex (MAC) along potable water distribution pipelines.

Whiley H, Keegan A, Fallowfield H, Bentham R.

Int J Environ Res Public Health. 2014 Jul 18;11(7):7393-405. doi: 10.3390/ijerph110707393. Erratum in: Int J Environ Res Public Health. 2014 Nov;11(11):1418-20.


Immune status influences fear and anxiety responses in mice after acute stress exposure.

Clark SM, Sand J, Francis TC, Nagaraju A, Michael KC, Keegan AD, Kusnecov A, Gould TD, Tonelli LH.

Brain Behav Immun. 2014 May;38:192-201. doi: 10.1016/j.bbi.2014.02.001. Epub 2014 Feb 10.


Neuroimmune semaphorin 4A as a drug and drug target for asthma.

Mogie G, Shanks K, Nkyimbeng-Takwi EH, Smith E, Davila E, Lipsky MM, DeTolla LJ, Keegan AD, Chapoval SP.

Int Immunopharmacol. 2013 Nov;17(3):568-75. doi: 10.1016/j.intimp.2013.08.005. Epub 2013 Aug 28.


Absence of the common gamma chain (γ(c)), a critical component of the Type I IL-4 receptor, increases the severity of allergic lung inflammation.

Dasgupta P, Qi X, Smith EP, Keegan AD.

PLoS One. 2013 Aug 5;8(8):e71344. doi: 10.1371/journal.pone.0071344. Print 2013.


Neuroimmune semaphorin 4D is necessary for optimal lung allergic inflammation.

Shanks K, Nkyimbeng-Takwi EH, Smith E, Lipsky MM, DeTolla LJ, Scott DW, Keegan AD, Chapoval SP.

Mol Immunol. 2013 Dec;56(4):480-7. doi: 10.1016/j.molimm.2013.05.228. Epub 2013 Aug 1.


STAT6 controls the number of regulatory T cells in vivo, thereby regulating allergic lung inflammation.

Dorsey NJ, Chapoval SP, Smith EP, Skupsky J, Scott DW, Keegan AD.

J Immunol. 2013 Aug 15;191(4):1517-28. doi: 10.4049/jimmunol.1300486. Epub 2013 Jul 3.


IRS1 is highly expressed in localized breast tumors and regulates the sensitivity of breast cancer cells to chemotherapy, while IRS2 is highly expressed in invasive breast tumors.

Porter HA, Perry A, Kingsley C, Tran NL, Keegan AD.

Cancer Lett. 2013 Sep 28;338(2):239-48. doi: 10.1016/j.canlet.2013.03.030. Epub 2013 Apr 2.


Dissociation of endotoxin tolerance and differentiation of alternatively activated macrophages.

Rajaiah R, Perkins DJ, Polumuri SK, Zhao A, Keegan AD, Vogel SN.

J Immunol. 2013 May 1;190(9):4763-72. doi: 10.4049/jimmunol.1202407. Epub 2013 Mar 29.


Macrophages as IL-25/IL-33-responsive cells play an important role in the induction of type 2 immunity.

Yang Z, Grinchuk V, Urban JF Jr, Bohl J, Sun R, Notari L, Yan S, Ramalingam T, Keegan AD, Wynn TA, Shea-Donohue T, Zhao A.

PLoS One. 2013;8(3):e59441. doi: 10.1371/journal.pone.0059441. Epub 2013 Mar 25.


Cytokines in chronic respiratory diseases.

Atamas SP, Chapoval SP, Keegan AD.

F1000 Biol Rep. 2013;5:3. doi: 10.3410/B5-3. Epub 2013 Feb 1.


Dissection of the hierarchy and synergism of the bile derived signal on Cryptosporidium parvum excystation and infectivity.

King BJ, Keegan AR, Phillips R, Fanok S, Monis PT.

Parasitology. 2012 Oct;139(12):1533-46. doi: 10.1017/S0031182012000984. Epub 2012 Aug 16.


Regulation of inflammation by interleukin-4: a review of "alternatives".

Luzina IG, Keegan AD, Heller NM, Rook GA, Shea-Donohue T, Atamas SP.

J Leukoc Biol. 2012 Oct;92(4):753-64. doi: 10.1189/jlb.0412214. Epub 2012 Jul 10. Review.


IL-4 engagement of the type I IL-4 receptor complex enhances mouse eosinophil migration to eotaxin-1 in vitro.

Heller NM, Gwinn WM, Donnelly RP, Constant SL, Keegan AD.

PLoS One. 2012;7(6):e39673. doi: 10.1371/journal.pone.0039673. Epub 2012 Jun 28.


Insulin receptor substrate 1 expression enhances the sensitivity of 32D cells to chemotherapy-induced cell death.

Porter HA, Carey GB, Keegan AD.

Exp Cell Res. 2012 Aug 15;318(14):1745-58. doi: 10.1016/j.yexcr.2012.04.020. Epub 2012 May 28.


Neuroimmune semaphorin 4A downregulates the severity of allergic response.

Nkyimbeng-Takwi EH, Shanks K, Smith E, Iyer A, Lipsky MM, Detolla LJ, Kikutani H, Keegan AD, Chapoval SP.

Mucosal Immunol. 2012 Jul;5(4):409-19. doi: 10.1038/mi.2012.18. Epub 2012 Apr 4.


Mycobacterium avium complex--the role of potable water in disease transmission.

Whiley H, Keegan A, Giglio S, Bentham R.

J Appl Microbiol. 2012 Aug;113(2):223-32. doi: 10.1111/j.1365-2672.2012.05298.x. Epub 2012 Apr 25. Review.


Contribution of alternatively activated macrophages to allergic lung inflammation: a tale of mice and men.

Dasgupta P, Keegan AD.

J Innate Immun. 2012;4(5-6):478-88. doi: 10.1159/000336025. Epub 2012 Mar 21.


Adoptive transfer of IL-4Rα+ macrophages is sufficient to enhance eosinophilic inflammation in a mouse model of allergic lung inflammation.

Ford AQ, Dasgupta P, Mikhailenko I, Smith EM, Noben-Trauth N, Keegan AD.

BMC Immunol. 2012 Jan 31;13:6. doi: 10.1186/1471-2172-13-6.


Suppression of the inflammatory immune response prevents the development of chronic biofilm infection due to methicillin-resistant Staphylococcus aureus.

Prabhakara R, Harro JM, Leid JG, Keegan AD, Prior ML, Shirtliff ME.

Infect Immun. 2011 Dec;79(12):5010-8. doi: 10.1128/IAI.05571-11. Epub 2011 Sep 26.


NF-κB signaling participates in both RANKL- and IL-4-induced macrophage fusion: receptor cross-talk leads to alterations in NF-κB pathways.

Yu M, Qi X, Moreno JL, Farber DL, Keegan AD.

J Immunol. 2011 Aug 15;187(4):1797-806. doi: 10.4049/jimmunol.1002628. Epub 2011 Jul 6.

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