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Items: 1 to 50 of 57

1.

Organic Anion Transporter 2 Mediates Hepatic Uptake of Tolbutamide, a CYP2C9 Probe Drug.

Bi YA, Mathialagan S, Tylaska L, Fu M, Keefer J, Vildhede A, Costales C, Rodrigues AD, Varma MVS.

J Pharmacol Exp Ther. 2018 Mar;364(3):390-398. doi: 10.1124/jpet.117.245951. Epub 2018 Jan 11.

PMID:
29326367
2.

Development of a high-performance, enterprise-level, multimode LC-MS/MS autosampler for drug discovery.

Kapinos B, Liu J, Piotrowski M, Keefer J, Holder B, Janiszewski J, Zhang H, Troutman M.

Bioanalysis. 2017 Nov;9(21):1643-1654. doi: 10.4155/bio-2017-0149. Epub 2017 Nov 9. No abstract available.

PMID:
29120233
3.

Identification of Aptamers That Bind to Sickle Hemoglobin and Inhibit Its Polymerization.

Purvis SH, Keefer JR, Fortenberry YM, Barron-Casella EA, Casella JF.

Nucleic Acid Ther. 2017 Dec;27(6):354-364. doi: 10.1089/nat.2016.0646. Epub 2017 Oct 17.

PMID:
29039727
4.

Clinical evaluation of combined azacitidine and entinostat on the induction of fetal hemoglobin in patients with acute myeloid leukemias and myelodysplastic syndromes.

Press KR, Uy N, Keefer J, Gore SD, Carraway HE, Sakoian S, Prebet T.

Leuk Lymphoma. 2018 Mar;59(3):755-757. doi: 10.1080/10428194.2017.1354373. Epub 2017 Jul 25. No abstract available.

PMID:
28738707
5.

Biologics Development and Carrier Innovation.

Kim KD, Koleva PM, Keefer JH, Han CE, Ralston SE, Lee CC.

Spine (Phila Pa 1976). 2017 Apr 1;42 Suppl 7:S9. doi: 10.1097/BRS.0000000000002023. No abstract available.

PMID:
28296692
6.

Erratum to: Reliable Rate Measurements for Active and Passive Hepatic Uptake Using Plated Human Hepatocytes.

Bi YA, Scialis RJ, Lazzaro S, Mathialagan S, Kimoto E, Keefer J, Zhang H, Vildhede AM, Costales C, Rodrigues AD, Tremaine LM, Varma MVS.

AAPS J. 2017 May;19(3):882. doi: 10.1208/s12248-017-0061-0. No abstract available.

PMID:
28233243
7.

Reliable Rate Measurements for Active and Passive Hepatic Uptake Using Plated Human Hepatocytes.

Bi YA, Scialis RJ, Lazzaro S, Mathialagan S, Kimoto E, Keefer J, Zhang H, Vildhede AM, Costales C, Rodrigues AD, Tremaine LM, Varma MVS.

AAPS J. 2017 May;19(3):787-796. doi: 10.1208/s12248-017-0051-2. Epub 2017 Feb 10. Erratum in: AAPS J. 2017 May;19(3):882.

PMID:
28188574
8.

Assessment of Bile Salt Export Pump (BSEP) Inhibition in Membrane Vesicles Using Radioactive and LC/MS-Based Detection Methods.

Marroquin LD, Bonin PD, Keefer J, Schroeter T.

Curr Protoc Toxicol. 2017 Feb 1;71:14.14.1-14.14.20. doi: 10.1002/cptx.15.

PMID:
28146280
9.

A critical role for the host mediator macrophage migration inhibitory factor in the pathogenesis of malarial anemia.

McDevitt MA, Xie J, Ganapathy-Kanniappan S, Griffith J, Liu A, McDonald C, Thuma P, Gordeuk VR, Metz CN, Mitchell R, Keefer J, David J, Leng L, Bucala R.

J Exp Med. 2015 May 4;212(5):825. doi: 10.1084/jem.2005239804172015c. No abstract available.

10.

Seasonal variation of urinary microRNA expression in male goats (Capra hircus) as assessed by next generation sequencing.

Longpre KM, Kinstlinger NS, Mead EA, Wang Y, Thekkumthala AP, Carreno KA, Hot A, Keefer JM, Tully L, Katz LS, Pietrzykowski AZ.

Gen Comp Endocrinol. 2014 Apr 1;199:1-15. doi: 10.1016/j.ygcen.2014.01.002. Epub 2014 Jan 20.

PMID:
24457251
11.

Acute chest syndrome is associated with single nucleotide polymorphism-defined beta globin cluster haplotype in children with sickle cell anaemia.

Bean CJ, Boulet SL, Yang G, Payne AB, Ghaji N, Pyle ME, Hooper WC, Bhatnagar P, Keefer J, Barron-Casella EA, Casella JF, Debaun MR.

Br J Haematol. 2013 Oct;163(2):268-76. doi: 10.1111/bjh.12507. Epub 2013 Aug 16.

12.

Association between baseline fetal hemoglobin levels and incidence of severe vaso-occlusive pain episodes in children with sickle cell anemia.

Bhatnagar P, Keefer JR, Casella JF, Barron-Casella EA, Bean CJ, Hooper CW, Payne AB, Arking DE, Debaun MR.

Pediatr Blood Cancer. 2013 Oct;60(10):E125-7. doi: 10.1002/pbc.24588. Epub 2013 May 15.

13.

Sickle cell vaso-occlusion causes activation of iNKT cells that is decreased by the adenosine A2A receptor agonist regadenoson.

Field JJ, Lin G, Okam MM, Majerus E, Keefer J, Onyekwere O, Ross A, Campigotto F, Neuberg D, Linden J, Nathan DG.

Blood. 2013 Apr 25;121(17):3329-34. doi: 10.1182/blood-2012-11-465963. Epub 2013 Feb 1.

14.

Sickle cell disease (SCD), iNKT cells, and regadenoson infusion.

Nathan DG, Field J, Lin G, Neuberg D, Majerus E, Onyekwere O, Keefer J, Okam M, Ross A, Linden J.

Trans Am Clin Climatol Assoc. 2012;123:312-7; discussion 317-8.

15.

Informal caregivers of older adults at home: let's PREPARE!

Atkins B, Kowalski JP, Keefer JM, Silver G, Lewis-Holman S.

Medsurg Nurs. 2012 Sep-Oct;21(5):317-8. No abstract available.

PMID:
23243794
16.

Meta-analysis of 2040 sickle cell anemia patients: BCL11A and HBS1L-MYB are the major modifiers of HbF in African Americans.

Bae HT, Baldwin CT, Sebastiani P, Telen MJ, Ashley-Koch A, Garrett M, Hooper WC, Bean CJ, Debaun MR, Arking DE, Bhatnagar P, Casella JF, Keefer JR, Barron-Casella E, Gordeuk V, Kato GJ, Minniti C, Taylor J, Campbell A, Luchtman-Jones L, Hoppe C, Gladwin MT, Zhang Y, Steinberg MH.

Blood. 2012 Aug 30;120(9):1961-2. doi: 10.1182/blood-2012-06-432849. No abstract available.

17.

A phase 1/2 trial of HQK-1001, an oral fetal globin inducer, in sickle cell disease.

Kutlar A, Ataga K, Reid M, Vichinsky EP, Neumayr L, Blair-Britt L, Labotka R, Glass J, Keefer JR, Wargin WA, Berenson R, Perrine SP.

Am J Hematol. 2012 Nov;87(11):1017-21. doi: 10.1002/ajh.23306. Epub 2012 Aug 7.

18.

Activation of the stress proteome as a mechanism for small molecule therapeutics.

Brose RD, Shin G, McGuinness MC, Schneidereith T, Purvis S, Dong GX, Keefer J, Spencer F, Smith KD.

Hum Mol Genet. 2012 Oct 1;21(19):4237-52. doi: 10.1093/hmg/dds247. Epub 2012 Jul 2.

19.

α-Thalassemia impairs the cytoadherence of Plasmodium falciparum-infected erythrocytes.

Krause MA, Diakite SA, Lopera-Mesa TM, Amaratunga C, Arie T, Traore K, Doumbia S, Konate D, Keefer JR, Diakite M, Fairhurst RM.

PLoS One. 2012;7(5):e37214. doi: 10.1371/journal.pone.0037214. Epub 2012 May 18.

20.

A case study of a child with chronic hemolytic anemia due to a Donath-Landsteiner positive, IgM anti-I autoantibody.

Karafin MS, Shirey RS, Ness PM, King KE, Keefer J.

Pediatr Blood Cancer. 2012 Nov;59(5):953-5. doi: 10.1002/pbc.24185. Epub 2012 May 2.

PMID:
22553072
21.

Opioid patient controlled analgesia use during the initial experience with the IMPROVE PCA trial: a phase III analgesic trial for hospitalized sickle cell patients with painful episodes.

Dampier CD, Smith WR, Kim HY, Wager CG, Bell MC, Minniti CP, Keefer J, Hsu L, Krishnamurti L, Mack AK, McClish D, McKinlay SM, Miller ST, Osunkwo I, Seaman P, Telen MJ, Weiner DL; Investigators of the Sickle Cell Disease Clinical Research Network (SCDCRN).

Am J Hematol. 2011 Dec;86(12):E70-3. doi: 10.1002/ajh.22176. Epub 2011 Sep 22.

22.

Subtotal splenic embolization is a safe and effective treatment for isolated splenic vascular tumors associated with consumptive coagulopathy.

Raabe EH, Keefer JR, Mitchell SE, Hong K, DiFazio M, Strouse JJ.

J Pediatr Hematol Oncol. 2011 Jul;33(5):383-6. doi: 10.1097/MPH.0b013e3182172515.

23.

A role for fetal hemoglobin and maternal immune IgG in infant resistance to Plasmodium falciparum malaria.

Amaratunga C, Lopera-Mesa TM, Brittain NJ, Cholera R, Arie T, Fujioka H, Keefer JR, Fairhurst RM.

PLoS One. 2011 Apr 12;6(4):e14798. doi: 10.1371/journal.pone.0014798.

24.

Evaluation of safety and pharmacokinetics of sodium 2,2 dimethylbutyrate, a novel short chain fatty acid derivative, in a phase 1, double-blind, placebo-controlled, single-dose, and repeat-dose studies in healthy volunteers.

Perrine SP, Wargin WA, Boosalis MS, Wallis WJ, Case S, Keefer JR, Faller DV, Welch WC, Berenson RJ.

J Clin Pharmacol. 2011 Aug;51(8):1186-94. doi: 10.1177/0091270010379810. Epub 2011 Mar 21.

25.

Genome-wide association study identifies genetic variants influencing F-cell levels in sickle-cell patients.

Bhatnagar P, Purvis S, Barron-Casella E, DeBaun MR, Casella JF, Arking DE, Keefer JR.

J Hum Genet. 2011 Apr;56(4):316-23. doi: 10.1038/jhg.2011.12. Epub 2011 Feb 17.

26.

Evidence-based practice improvement: merging 2 paradigms.

Levin RF, Keefer JM, Marren J, Vetter M, Lauder B, Sobolewski S.

J Nurs Care Qual. 2010 Apr-Jun;25(2):117-26. doi: 10.1097/NCQ.0b013e3181b5f19f.

PMID:
19680149
27.

Pediatric littoral cell angioma of the spleen: multimodality imaging including diffusion-weighted imaging.

Ertan G, Tekes A, Mitchell S, Keefer J, Huisman TA.

Pediatr Radiol. 2009 Oct;39(10):1105-9. doi: 10.1007/s00247-009-1339-x. Epub 2009 Jul 14.

PMID:
19597808
28.

Receptor reserve reflects differential intrinsic efficacy associated with opioid diastereomers.

Carliss RD, Keefer JF, Perschke S, Welch S, Rich TC, Weissman AD.

Pharmacol Biochem Behav. 2009 May;92(3):495-502. doi: 10.1016/j.pbb.2009.01.019. Epub 2009 Jan 31.

PMID:
19463265
29.

Clinical evaluation of the shoulder shrug sign.

Jia X, Ji JH, Petersen SA, Keefer J, McFarland EG.

Clin Orthop Relat Res. 2008 Nov;466(11):2813-9. doi: 10.1007/s11999-008-0331-3. Epub 2008 Jun 10.

30.

Disciplinary perspectives on evidence-based practice: the more the merrier.

Singleton JK, Levin RF, Keefer J.

Res Theory Nurs Pract. 2007;21(4):213-6.

PMID:
18236766
31.
32.

Corticosteroids and increased risk of readmission after acute chest syndrome in children with sickle cell disease.

Strouse JJ, Takemoto CM, Keefer JR, Kato GJ, Casella JF.

Pediatr Blood Cancer. 2008 May;50(5):1006-12.

33.

Role of cyclic nucleotides in fetal hemoglobin induction in cultured CD34+ cells.

Keefer JR, Schneidereith TA, Mays A, Purvis SH, Dover GJ, Smith KD.

Exp Hematol. 2006 Sep;34(9):1151-61.

PMID:
16939808
34.

A critical role for the host mediator macrophage migration inhibitory factor in the pathogenesis of malarial anemia.

McDevitt MA, Xie J, Ganapathy-Kanniappan S, Griffith J, Liu A, McDonald C, Thuma P, Gordeuk VR, Metz CN, Mitchell R, Keefer J, David J, Leng L, Bucala R.

J Exp Med. 2006 May 15;203(5):1185-96. Epub 2006 Apr 24. Erratum in: J Exp Med. 2015 May 4;212(5):825. Shanmugasundaram, Ganapathy [Corrected to Ganapathy-Kanniappan, Shanmugasundaram].

35.

Gastrocnemius and soleus muscle length, velocity, and EMG responses to changes in pedalling cadence.

Sanderson DJ, Martin PE, Honeyman G, Keefer J.

J Electromyogr Kinesiol. 2006 Dec;16(6):642-9. Epub 2006 Jan 11.

PMID:
16377214
36.

Regulation of granulocyte and monocyte differentiation by CCAAT/enhancer binding protein alpha.

Friedman AD, Keefer JR, Kummalue T, Liu H, Wang QF, Cleaves R.

Blood Cells Mol Dis. 2003 Nov-Dec;31(3):338-41. Review.

PMID:
14636649
37.
38.
39.
40.

Differential targeting and retention of G protein-coupled receptors in polarized epithelial cells.

Wozniak M, Keefer JR, Saunders C, Limbird LE.

J Recept Signal Transduct Res. 1997 Jan-May;17(1-3):373-83. Review.

PMID:
9029502
46.
47.

Characterization of the soluble leukotriene B4 receptor from sheep lung membranes.

Votta B, Keefer J, Mong S.

Biochem J. 1990 Aug 15;270(1):213-8.

48.

Protein kinase C: a new linkage marker for growth hormone and for COL1A1.

Summar ML, Phillips JA 3rd, Krishnamani MR, Keefer J, Trofatter J, Schwartz RC, Tsipouras P, Willard H, Ullrich A.

Genomics. 1989 Jul;5(1):163-5.

PMID:
2570026
49.

Asparagine catabolism in rat liver mitochondria.

Moraga-Amador DA, MacPhee-Quiggley KM, Keefer JF, Schuster SM.

Arch Biochem Biophys. 1989 Jan;268(1):314-26.

PMID:
2912380
50.

Bradykinin analogs antagonize bradykinin-induced second messenger production in a sensory neuron cell line.

Francel PC, Keefer JF, Dawson G.

Mol Pharmacol. 1989 Jan;35(1):34-8.

PMID:
2536466

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