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Items: 36

1.

Novel mutation (R192C) in CYB5R3 gene causing NADH-cytochrome b5 reductase deficiency in eight Indian patients associated with autosomal recessive congenital methemoglobinemia type-I.

Kedar PS, Gupta V, Warang P, Chiddarwar A, Madkaikar M.

Hematology. 2018 Feb 27:1-7. doi: 10.1080/10245332.2018.1444920. [Epub ahead of print]

PMID:
29482478
2.

Erythrocytosis, methemoglobinemia, and the saturation gap.

Koduri PR, Kedar PS, Warang P.

Ann Hematol. 2015 Mar;94(3):509-10. doi: 10.1007/s00277-014-2179-9. Epub 2014 Aug 5. No abstract available.

PMID:
25091522
3.

Base excision repair defects invoke hypersensitivity to PARP inhibition.

Horton JK, Stefanick DF, Prasad R, Gassman NR, Kedar PS, Wilson SH.

Mol Cancer Res. 2014 Aug;12(8):1128-39. doi: 10.1158/1541-7786.MCR-13-0502. Epub 2014 Apr 25.

4.

Clinical spectrum and molecular basis of recessive congenital methemoglobinemia in India.

Warang PP, Kedar PS, Shanmukaiah C, Ghosh K, Colah RB.

Clin Genet. 2015;87(1):62-7. doi: 10.1111/cge.12326. Epub 2013 Dec 20.

PMID:
24266649
5.

Preventing oxidation of cellular XRCC1 affects PARP-mediated DNA damage responses.

Horton JK, Stefanick DF, Gassman NR, Williams JG, Gabel SA, Cuneo MJ, Prasad R, Kedar PS, Derose EF, Hou EW, London RE, Wilson SH.

DNA Repair (Amst). 2013 Sep;12(9):774-85. doi: 10.1016/j.dnarep.2013.06.004. Epub 2013 Jul 18.

6.

Interaction between DNA Polymerase β and BRCA1.

Masaoka A, Gassman NR, Horton JK, Kedar PS, Witt KL, Hobbs CA, Kissling GE, Tano K, Asagoshi K, Wilson SH.

PLoS One. 2013 Jun 27;8(6):e66801. doi: 10.1371/journal.pone.0066801. Print 2013.

7.

Hyperactivation of PARP triggers nonhomologous end-joining in repair-deficient mouse fibroblasts.

Gassman NR, Stefanick DF, Kedar PS, Horton JK, Wilson SH.

PLoS One. 2012;7(11):e49301. doi: 10.1371/journal.pone.0049301. Epub 2012 Nov 7.

8.

HMGN1 protein regulates poly(ADP-ribose) polymerase-1 (PARP-1) self-PARylation in mouse fibroblasts.

Masaoka A, Gassman NR, Kedar PS, Prasad R, Hou EW, Horton JK, Bustin M, Wilson SH.

J Biol Chem. 2012 Aug 10;287(33):27648-58. doi: 10.1074/jbc.M112.370759. Epub 2012 Jun 26.

9.

Increased PARP-1 association with DNA in alkylation damaged, PARP-inhibited mouse fibroblasts.

Kedar PS, Stefanick DF, Horton JK, Wilson SH.

Mol Cancer Res. 2012 Mar;10(3):360-8. doi: 10.1158/1541-7786.MCR-11-0477. Epub 2012 Jan 13.

10.

Severe mental retardation and recessive congenital methemoglobinemia in three Indian patients: compound heterozygous for NADH-cytochrome b5 reductase gene mutations.

Kedar PS, Warang P, Ghosh K, Colah RB.

Am J Hematol. 2011 Mar;86(3):327-9. doi: 10.1002/ajh.21956. Epub 2011 Feb 15. No abstract available.

11.

Functional characterization and modified rescue of novel AE1 mutation R730C associated with overhydrated cation leak stomatocytosis.

Stewart AK, Kedar PS, Shmukler BE, Vandorpe DH, Hsu A, Glader B, Rivera A, Brugnara C, Alper SL.

Am J Physiol Cell Physiol. 2011 May;300(5):C1034-46. doi: 10.1152/ajpcell.00447.2010. Epub 2011 Jan 5.

12.

Base excision repair and design of small molecule inhibitors of human DNA polymerase β.

Wilson SH, Beard WA, Shock DD, Batra VK, Cavanaugh NA, Prasad R, Hou EW, Liu Y, Asagoshi K, Horton JK, Stefanick DF, Kedar PS, Carrozza MJ, Masaoka A, Heacock ML.

Cell Mol Life Sci. 2010 Nov;67(21):3633-47. doi: 10.1007/s00018-010-0489-1. Epub 2010 Sep 16. Review.

13.

DNA polymerases beta and lambda mediate overlapping and independent roles in base excision repair in mouse embryonic fibroblasts.

Braithwaite EK, Kedar PS, Stumpo DJ, Bertocci B, Freedman JH, Samson LD, Wilson SH.

PLoS One. 2010 Aug 18;5(8):e12229. doi: 10.1371/journal.pone.0012229.

14.

Hemolytic anemia and distal renal tubular acidosis in two Indian patients homozygous for SLC4A1/AE1 mutation A858D.

Shmukler BE, Kedar PS, Warang P, Desai M, Madkaikar M, Ghosh K, Colah RB, Alper SL.

Am J Hematol. 2010 Oct;85(10):824-8. doi: 10.1002/ajh.21836.

15.

PARP inhibition during alkylation-induced genotoxic stress signals a cell cycle checkpoint response mediated by ATM.

Carrozza MJ, Stefanick DF, Horton JK, Kedar PS, Wilson SH.

DNA Repair (Amst). 2009 Nov 2;8(11):1264-72. doi: 10.1016/j.dnarep.2009.07.010. Epub 2009 Aug 31.

16.

Interaction between PARP-1 and ATR in mouse fibroblasts is blocked by PARP inhibition.

Kedar PS, Stefanick DF, Horton JK, Wilson SH.

DNA Repair (Amst). 2008 Nov 1;7(11):1787-98. doi: 10.1016/j.dnarep.2008.07.006. Epub 2008 Aug 22.

17.

A novel R198H mutation in the glucose-6-phosphate dehydrogenase gene in the tribal groups of the Nilgiris in Southern India.

Chalvam R, Kedar PS, Colah RB, Ghosh K, Mukherjee MB.

J Hum Genet. 2008;53(2):181-4. Epub 2007 Nov 28.

PMID:
18043863
18.

A novel G143D mutation in the NADH-cytochrome b5 reductase gene in an Indian patient with type I recessive hereditary methemoglobinemia.

Kedar PS, Warang P, Nadkarni AH, Colah RB, Ghosh K.

Blood Cells Mol Dis. 2008 May-Jun;40(3):323-7. Epub 2007 Oct 25.

PMID:
17964195
19.

First-trimester prenatal diagnosis of pyruvate kinase deficiency in an Indian family with the pyruvate kinase-Amish mutation.

Kedar PS, Nampoothiri S, Sreedhar S, Ghosh K, Shimizu K, Kanno H, Colah RB.

Genet Mol Res. 2007 Jun 30;6(2):470-5.

PMID:
17952871
20.

HMGB1 is a cofactor in mammalian base excision repair.

Prasad R, Liu Y, Deterding LJ, Poltoratsky VP, Kedar PS, Horton JK, Kanno S, Asagoshi K, Hou EW, Khodyreva SN, Lavrik OI, Tomer KB, Yasui A, Wilson SH.

Mol Cell. 2007 Sep 7;27(5):829-41.

21.

Coordination of steps in single-nucleotide base excision repair mediated by apurinic/apyrimidinic endonuclease 1 and DNA polymerase beta.

Liu Y, Prasad R, Beard WA, Kedar PS, Hou EW, Shock DD, Wilson SH.

J Biol Chem. 2007 May 4;282(18):13532-41. Epub 2007 Mar 12.

22.

ATR signaling mediates an S-phase checkpoint after inhibition of poly(ADP-ribose) polymerase activity.

Horton JK, Stefanick DF, Kedar PS, Wilson SH.

DNA Repair (Amst). 2007 Jun 1;6(6):742-50. Epub 2007 Feb 9.

23.

Red cell pyruvate kinase deficiency in neonatal jaundice cases in India.

Kedar PS, Warang P, Colah RB, Mohanty D.

Indian J Pediatr. 2006 Nov;73(11):985-8.

PMID:
17127778
24.

DNA polymerase lambda protects mouse fibroblasts against oxidative DNA damage and is recruited to sites of DNA damage/repair.

Braithwaite EK, Kedar PS, Lan L, Polosina YY, Asagoshi K, Poltoratsky VP, Horton JK, Miller H, Teebor GW, Yasui A, Wilson SH.

J Biol Chem. 2005 Sep 9;280(36):31641-7. Epub 2005 Jul 7.

25.

Congenital methemoglobinemia caused by Hb-MRatnagiri (beta-63CAT-->TAT, His-->Tyr) in an Indian family.

Kedar PS, Nadkarni AH, Phanasgoankar S, Madkaikar M, Ghosh K, Gorakshakar AC, Colah RB, Mohanty D.

Am J Hematol. 2005 Jun;79(2):168-70.

26.

Poly(ADP-ribose) polymerase activity prevents signaling pathways for cell cycle arrest after DNA methylating agent exposure.

Horton JK, Stefanick DF, Naron JM, Kedar PS, Wilson SH.

J Biol Chem. 2005 Apr 22;280(16):15773-85. Epub 2005 Feb 7.

27.

Hereditary spherocytosis in association with severe G6PD deficiency: report of an unusual case.

Kedar PS, Colah RB, Ghosh K, Mohanty D.

Clin Chim Acta. 2004 Jun;344(1-2):221-4. No abstract available.

PMID:
15149895
28.

Experience with eosin-5'-maleimide as a diagnostic tool for red cell membrane cytoskeleton disorders.

Kedar PS, Colah RB, Kulkarni S, Ghosh K, Mohanty D.

Clin Lab Haematol. 2003 Dec;25(6):373-6.

PMID:
14641141
29.

Congenital methemoglobinemia due to NADH-methemoglobin reductase deficiency in three Indian families.

Kedar PS, Colah RB, Ghosh K, Mohanty D.

Haematologia (Budap). 2002;32(4):543-9.

PMID:
12803131
30.

The Werner syndrome protein stimulates DNA polymerase beta strand displacement synthesis via its helicase activity.

Harrigan JA, Opresko PL, von Kobbe C, Kedar PS, Prasad R, Wilson SH, Bohr VA.

J Biol Chem. 2003 Jun 20;278(25):22686-95. Epub 2003 Mar 27.

31.

Direct interaction between mammalian DNA polymerase beta and proliferating cell nuclear antigen.

Kedar PS, Kim SJ, Robertson A, Hou E, Prasad R, Horton JK, Wilson SH.

J Biol Chem. 2002 Aug 23;277(34):31115-23. Epub 2002 Jun 12.

32.

Chronic persistent hemolysis in an infant: can we afford to forget malaria as a cause?

Kedar PS, Ghosh K, Colah RB, Mohanty D.

Hematol J. 2002;3(2):114-5. No abstract available.

PMID:
12032873
33.

Umbilical Cord Blood Mononuclear Cell HIV-1 LTR Binding Activities.

Kedar PS, Arden K, Foyle M, Pope JH, Zeichner SL.

J Biomed Sci. 1997;4(5):217-228.

PMID:
12386383
34.
35.

Transfected human beta-polymerase promoter contains a ras-responsive element.

Kedar PS, Lowy DR, Widen SG, Wilson SH.

Mol Cell Biol. 1990 Jul;10(7):3852-6.

36.

Mechanism of HIV reverse transcriptase: enzyme-primer interaction as revealed through studies of a dNTP analogue, 3'-azido-dTTP.

Kedar PS, Abbotts J, Kovács T, Lesiak K, Torrence P, Wilson SH.

Biochemistry. 1990 Apr 17;29(15):3603-11. Erratum in: Biochemistry 1990 Sep 4;29(35):8198.

PMID:
1692732

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