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Items: 7


Clarifying the Mechanism of Copper(II) α-(N)-Heterocyclic Thiosemicarbazone Complexes on DNA Topoisomerase IIα and IIβ.

Keck JM, Conner JD, Wilson JT, Jiang X, Lisic EC, Deweese JE.

Chem Res Toxicol. 2019 Oct 21;32(10):2135-2143. doi: 10.1021/acs.chemrestox.9b00311. Epub 2019 Sep 20.


Implementing a comprehensive translational oncology platform: from molecular testing to actionability.

Mitri ZI, Parmar S, Johnson B, Kolodzie A, Keck JM, Morris M, Guimaraes AR, Beckett BR, Borate U, Lopez CD, Kemmer KA, Alumkal JJ, Beer TM, Corless CL, Mills GB, Gray JW, Bergan RC.

J Transl Med. 2018 Dec 14;16(1):358. doi: 10.1186/s12967-018-1733-y.


Activation of the yeast Hippo pathway by phosphorylation-dependent assembly of signaling complexes.

Rock JM, Lim D, Stach L, Ogrodowicz RW, Keck JM, Jones MH, Wong CC, Yates JR 3rd, Winey M, Smerdon SJ, Yaffe MB, Amon A.

Science. 2013 May 17;340(6134):871-5. doi: 10.1126/science.1235822. Epub 2013 Apr 11.


Cell cycle phosphorylation of mitotic exit network (MEN) proteins.

Jones MH, Keck JM, Wong CC, Xu T, Yates JR 3rd, Winey M.

Cell Cycle. 2011 Oct 15;10(20):3435-40. doi: 10.4161/cc.10.20.17790. Epub 2011 Oct 15.


A cell cycle phosphoproteome of the yeast centrosome.

Keck JM, Jones MH, Wong CC, Binkley J, Chen D, Jaspersen SL, Holinger EP, Xu T, Niepel M, Rout MP, Vogel J, Sidow A, Yates JR 3rd, Winey M.

Science. 2011 Jun 24;332(6037):1557-61. doi: 10.1126/science.1205193.


Cyclin E overexpression impairs progression through mitosis by inhibiting APC(Cdh1).

Keck JM, Summers MK, Tedesco D, Ekholm-Reed S, Chuang LC, Jackson PK, Reed SI.

J Cell Biol. 2007 Jul 30;178(3):371-85.


Deregulated cyclin E promotes p53 loss of heterozygosity and tumorigenesis in the mouse mammary gland.

Smith AP, Henze M, Lee JA, Osborn KG, Keck JM, Tedesco D, Bortner DM, Rosenberg MP, Reed SI.

Oncogene. 2006 Nov 23;25(55):7245-59. Epub 2006 Jun 5.


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