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Items: 37


Glycoamino Acid Analogues of the Thomsen-Friedenreich Tumor-Associated Carbohydrate Antigen: Synthesis and Evaluation of Novel Antiproliferative Factor Glycopeptides.

Siddiqui MA, Ambre S, Keay SK, Rhyne JM, Zhang CO, Barchi JJ Jr.

ACS Omega. 2017 Sep 30;2(9):5618-5632. doi: 10.1021/acsomega.7b01018. Epub 2017 Sep 8.


Death-associated Protein Kinase-1 Expression and Autophagy in Chronic Lymphocytic Leukemia Are Dependent on Activating Transcription Factor-6 and CCAAT/Enhancer-binding Protein-β.

Gade P, Kimball AS, DiNardo AC, Gangwal P, Ross DD, Boswell HS, Keay SK, Kalvakolanu DV.

J Biol Chem. 2016 Oct 14;291(42):22030-22042. Epub 2016 Sep 2.


Varicella-Zoster Virus Vasculopathy: A Case Report Demonstrating Vasculitis using Black-Blood MRI.

Shah J, Poonawala H, Keay SK, Serulle Y, Steven A, Gandhi D, Cole JW.

J Neurol Neurophysiol. 2015 Dec;6(6). pii: 1000342. Epub 2015 Dec 28.


Evidence for bladder urothelial pathophysiology in functional bladder disorders.

Keay SK, Birder LA, Chai TC.

Biomed Res Int. 2014;2014:865463. doi: 10.1155/2014/865463. Epub 2014 May 8. Review.


Monoallelic loss of tumor suppressor GRIM-19 promotes tumorigenesis in mice.

Kalakonda S, Nallar SC, Jaber S, Keay SK, Rorke E, Munivenkatappa R, Lindner DJ, Fiskum GM, Kalvakolanu DV.

Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):E4213-22. doi: 10.1073/pnas.1303760110. Epub 2013 Oct 21.


Safety of zoster vaccine in elderly adults following documented herpes zoster.

Morrison VA, Oxman MN, Levin MJ, Schmader KE, Guatelli JC, Betts RF, Gelb LD, Pachucki CT, Keay SK, Menzies B, Griffin MR, Kauffman CA, Marques AR, Toney JF, Simberkoff MS, Serrao R, Arbeit RD, Gnann JW, Greenberg RN, Holodniy M, Keitel WA, Yeh SS, Davis LE, Crawford GE, Neuzil KM, Johnson GR, Zhang JH, Harbecke R, Chan IS, Keller PM, Williams HM, Boardman KD, Silber JL, Annunziato PW; Shingles Prevention Study Group.

J Infect Dis. 2013 Aug 15;208(4):559-63. doi: 10.1093/infdis/jit182. Epub 2013 Apr 30.


A synthetic form of frizzled 8-associated antiproliferative factor enhances p53 stability through USP2a and MDM2.

Kim J, Keay SK, You S, Loda M, Freeman MR.

PLoS One. 2012;7(12):e50392. doi: 10.1371/journal.pone.0050392. Epub 2012 Dec 6.


Integration analysis of quantitative proteomics and transcriptomics data identifies potential targets of frizzled-8 protein-related antiproliferative factor in vivo.

Yang W, Kim Y, Kim TK, Keay SK, Kim KP, Steen H, Freeman MR, Hwang D, Kim J.

BJU Int. 2012 Dec;110(11 Pt C):E1138-46. doi: 10.1111/j.1464-410X.2012.11299.x. Epub 2012 Jun 28.


Quantitative proteomics identifies a beta-catenin network as an element of the signaling response to Frizzled-8 protein-related antiproliferative factor.

Yang W, Chung YG, Kim Y, Kim TK, Keay SK, Zhang CO, Ji M, Hwang D, Kim KP, Steen H, Freeman MR, Kim J.

Mol Cell Proteomics. 2011 Jun;10(6):M110.007492. doi: 10.1074/mcp.M110.007492. Epub 2011 Mar 21.


Antiproliferative factor decreases Akt phosphorylation and alters gene expression via CKAP4 in T24 bladder carcinoma cells.

Shahjee HM, Koch KR, Guo L, Zhang CO, Keay SK.

J Exp Clin Cancer Res. 2010 Dec 10;29:160. doi: 10.1186/1756-9966-29-160.


An hTERT-immortalized human urothelial cell line that responds to anti-proliferative factor.

Kim J, Ji M, DiDonato JA, Rackley RR, Kuang M, Sadhukhan PC, Mauney JR, Keay SK, Freeman MR, Liou LS, Adam RM.

In Vitro Cell Dev Biol Anim. 2011 Jan;47(1):2-9. doi: 10.1007/s11626-010-9350-y. Epub 2010 Dec 7.


Structure-Activity Studies on Antiproliferative Factor (APF) Glycooctapeptide Derivatives.

Kaczmarek P, Tocci GM, Keay SK, Adams KM, Zhang CO, Koch KR, Grkovic D, Guo L, Michejda CJ, Barchi JJ Jr.

ACS Med Chem Lett. 2010 Jul 19;1(8):390-4. doi: 10.1021/ml100087a. eCollection 2010 Nov 11.


Palmitoylation of cytoskeleton associated protein 4 by DHHC2 regulates antiproliferative factor-mediated signaling.

Planey SL, Keay SK, Zhang CO, Zacharias DA.

Mol Biol Cell. 2009 Mar;20(5):1454-63. doi: 10.1091/mbc.E08-08-0849. Epub 2009 Jan 14.


Structure-activity relationship studies for the peptide portion of the bladder epithelial cell antiproliferative factor from interstitial cystitis patients.

Kaczmarek P, Keay SK, Tocci GM, Koch KR, Zhang CO, Barchi JJ Jr, Grkovic D, Guo L, Michejda CJ.

J Med Chem. 2008 Oct 9;51(19):5974-83. doi: 10.1021/jm8002763. Epub 2008 Sep 13.


Urine markers do not predict biopsy findings or presence of bladder ulcers in interstitial cystitis/painful bladder syndrome.

Erickson DR, Tomaszewski JE, Kunselman AR, Stetter CM, Peters KM, Rovner ES, Demers LM, Wheeler MA, Keay SK.

J Urol. 2008 May;179(5):1850-6. doi: 10.1016/j.juro.2008.01.047. Epub 2008 Mar 18.


Identification of CKAP4/p63 as a major substrate of the palmitoyl acyltransferase DHHC2, a putative tumor suppressor, using a novel proteomics method.

Zhang J, Planey SL, Ceballos C, Stevens SM Jr, Keay SK, Zacharias DA.

Mol Cell Proteomics. 2008 Jul;7(7):1378-88. doi: 10.1074/mcp.M800069-MCP200. Epub 2008 Feb 22.


Toxicokinetic study of recombinant human heparin-binding epidermal growth factor-like growth factor (rhHB-EGF) in female Sprague Dawley rats.

Coowanitwong I, Keay SK, Natarajan K, Garimella TS, Mason CW, Grkovic D, Bauer KS.

Pharm Res. 2008 Mar;25(3):542-50. Epub 2007 Aug 1.


p53 mediates interstitial cystitis antiproliferative factor (APF)-induced growth inhibition of human urothelial cells.

Kim J, Keay SK, Dimitrakov JD, Freeman MR.

FEBS Lett. 2007 Aug 7;581(20):3795-9. Epub 2007 Jul 2.


Changes in urine markers and symptoms after bladder distention for interstitial cystitis.

Erickson DR, Kunselman AR, Bentley CM, Peters KM, Rovner ES, Demers LM, Wheeler MA, Keay SK.

J Urol. 2007 Feb;177(2):556-60.


CKAP4/p63 is a receptor for the frizzled-8 protein-related antiproliferative factor from interstitial cystitis patients.

Conrads TP, Tocci GM, Hood BL, Zhang CO, Guo L, Koch KR, Michejda CJ, Veenstra TD, Keay SK.

J Biol Chem. 2006 Dec 8;281(49):37836-43. Epub 2006 Oct 8.


A vaccine to prevent herpes zoster and postherpetic neuralgia in older adults.

Oxman MN, Levin MJ, Johnson GR, Schmader KE, Straus SE, Gelb LD, Arbeit RD, Simberkoff MS, Gershon AA, Davis LE, Weinberg A, Boardman KD, Williams HM, Zhang JH, Peduzzi PN, Beisel CE, Morrison VA, Guatelli JC, Brooks PA, Kauffman CA, Pachucki CT, Neuzil KM, Betts RF, Wright PF, Griffin MR, Brunell P, Soto NE, Marques AR, Keay SK, Goodman RP, Cotton DJ, Gnann JW Jr, Loutit J, Holodniy M, Keitel WA, Crawford GE, Yeh SS, Lobo Z, Toney JF, Greenberg RN, Keller PM, Harbecke R, Hayward AR, Irwin MR, Kyriakides TC, Chan CY, Chan IS, Wang WW, Annunziato PW, Silber JL; Shingles Prevention Study Group.

N Engl J Med. 2005 Jun 2;352(22):2271-84.


Do the National Institute of Diabetes and Digestive and Kidney Diseases cystoscopic criteria associate with other clinical and objective features of interstitial cystitis?

Erickson DR, Tomaszewski JE, Kunselman AR, Bentley CM, Peters KM, Rovner ES, Demers LM, Wheeler MA, Keay SK.

J Urol. 2005 Jan;173(1):93-7.


An antiproliferative factor from interstitial cystitis patients is a frizzled 8 protein-related sialoglycopeptide.

Keay SK, Szekely Z, Conrads TP, Veenstra TD, Barchi JJ Jr, Zhang CO, Koch KR, Michejda CJ.

Proc Natl Acad Sci U S A. 2004 Aug 10;101(32):11803-8. Epub 2004 Jul 28.


The use of urine proteomic and metabonomic patterns for the diagnosis of interstitial cystitis and bacterial cystitis.

Van QN, Klose JR, Lucas DA, Prieto DA, Luke B, Collins J, Burt SK, Chmurny GN, Issaq HJ, Conrads TP, Veenstra TD, Keay SK.

Dis Markers. 2003-2004;19(4-5):169-83.


Interstitial cystitis antiproliferative factor (APF) as a cell-cycle modulator.

Rashid HH, Reeder JE, O'Connell MJ, Zhang CO, Messing EM, Keay SK.

BMC Urol. 2004 Apr 6;4:3.


Is interstitial cystitis an infectious disease?

Keay SK, Warren JW.

Int J Antimicrob Agents. 2002 Jun;19(6):480-3. Review.


A comparison of multiple urine markers for interstitial cystitis.

Erickson DR, Xie SX, Bhavanandan VP, Wheeler MA, Hurst RE, Demers LM, Kushner L, Keay SK.

J Urol. 2002 Jun;167(6):2461-9.


Interstitial cystitis.

Warren JW, Keay SK.

Curr Opin Urol. 2002 Jan;12(1):69-74. Review.


Nonbladder related symptoms in patients with interstitial cystitis.

Erickson DR, Morgan KC, Ordille S, Keay SK, Xie SX.

J Urol. 2001 Aug;166(2):557-61; discussion 561-2.


Concordance of interstitial cystitis in monozygotic and dizygotic twin pairs.

Warren JW, Keay SK, Meyers D, Xu J.

Urology. 2001 Jun;57(6 Suppl 1):22-5.


Sensitivity and specificity of antiproliferative factor, heparin-binding epidermal growth factor-like growth factor, and epidermal growth factor as urine markers for interstitial cystitis.

Keay SK, Zhang CO, Shoenfelt J, Erickson DR, Whitmore K, Warren JW, Marvel R, Chai T.

Urology. 2001 Jun;57(6 Suppl 1):9-14.


Pilot study of sequential oral antibiotics for the treatment of interstitial cystitis.

Warren JW, Horne LM, Hebel JR, Marvel RP, Keay SK, Chai TC.

J Urol. 2000 Jun;163(6):1685-8.


In vivo phase variation of Escherichia coli type 1 fimbrial genes in women with urinary tract infection.

Lim JK, Gunther NW 4th, Zhao H, Johnson DE, Keay SK, Mobley HL.

Infect Immun. 1998 Jul;66(7):3303-10.


Identification of GPCMV infected cells in vitro and in vivo with a monoclonal antibody.

Jones CT, Keay SK, Swoveland PT.

J Virol Methods. 1994 Jul;48(2-3):133-44.


Morbidity and mortality associated with herpes virus infections.

Keay SK.

Trans Assoc Life Insur Med Dir Am. 1991;74:122-32. Review. No abstract available.


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