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Items: 1 to 50 of 116

1.

Matrix crosslinking enhances macrophage adhesion, migration, and inflammatory activation.

Hsieh JY, Keating MT, Smith TD, Meli VS, Botvinick EL, Liu WF.

APL Bioeng. 2019 Mar 27;3(1):016103. doi: 10.1063/1.5067301. eCollection 2019 Mar.

2.

Sprouting angiogenesis induces significant mechanical heterogeneities and ECM stiffening across length scales in fibrin hydrogels.

Juliar BA, Keating MT, Kong YP, Botvinick EL, Putnam AJ.

Biomaterials. 2018 Apr;162:99-108. doi: 10.1016/j.biomaterials.2018.02.012. Epub 2018 Feb 6.

3.

Vascularization and innervation of slits within polydimethylsiloxane sheets in the subcutaneous space of athymic nude mice.

Gurlin RE, Keating MT, Li S, Lakey JR, de Feraudy S, Shergill BS, Botvinick EL.

J Tissue Eng. 2017 Jan 30;8:2041731417691645. doi: 10.1177/2041731417691645. eCollection 2017 Jan-Dec.

4.

Recapitulating the human tumor microenvironment: Colon tumor-derived extracellular matrix promotes angiogenesis and tumor cell growth.

Romero-López M, Trinh AL, Sobrino A, Hatch MM, Keating MT, Fimbres C, Lewis DE, Gershon PD, Botvinick EL, Digman M, Lowengrub JS, Hughes CC.

Biomaterials. 2017 Feb;116:118-129. doi: 10.1016/j.biomaterials.2016.11.034. Epub 2016 Nov 24.

5.

Activin-betaA signaling is required for zebrafish fin regeneration.

Jaźwińska A, Badakov R, Keating MT.

Curr Biol. 2007 Aug 21;17(16):1390-5. Epub 2007 Aug 2.

6.

Periostin induces proliferation of differentiated cardiomyocytes and promotes cardiac repair.

Kühn B, del Monte F, Hajjar RJ, Chang YS, Lebeche D, Arab S, Keating MT.

Nat Med. 2007 Aug;13(8):962-9. Epub 2007 Jul 15.

PMID:
17632525
7.

Impaired interaction between the slide helix and the C-terminus of Kir2.1: a novel mechanism of Andersen syndrome.

Decher N, Renigunta V, Zuzarte M, Soom M, Heinemann SH, Timothy KW, Keating MT, Daut J, Sanguinetti MC, Splawski I.

Cardiovasc Res. 2007 Sep 1;75(4):748-57. Epub 2007 May 10.

PMID:
17568571
8.

Transcriptional profiling of caudal fin regeneration in zebrafish.

Schebesta M, Lien CL, Engel FB, Keating MT.

ScientificWorldJournal. 2006 Jun 2;6 Suppl 1:38-54.

9.

FGF1/p38 MAP kinase inhibitor therapy induces cardiomyocyte mitosis, reduces scarring, and rescues function after myocardial infarction.

Engel FB, Hsieh PC, Lee RT, Keating MT.

Proc Natl Acad Sci U S A. 2006 Oct 17;103(42):15546-51. Epub 2006 Oct 10.

10.

The GSK-3 inhibitor BIO promotes proliferation in mammalian cardiomyocytes.

Tseng AS, Engel FB, Keating MT.

Chem Biol. 2006 Sep;13(9):957-63.

11.

Anillin localization defect in cardiomyocyte binucleation.

Engel FB, Schebesta M, Keating MT.

J Mol Cell Cardiol. 2006 Oct;41(4):601-12. Epub 2006 Aug 4.

PMID:
16889791
12.

Gene expression analysis of zebrafish heart regeneration.

Lien CL, Schebesta M, Makino S, Weber GJ, Keating MT.

PLoS Biol. 2006 Aug;4(8):e260.

13.

CACNA1H mutations in autism spectrum disorders.

Splawski I, Yoo DS, Stotz SC, Cherry A, Clapham DE, Keating MT.

J Biol Chem. 2006 Aug 4;281(31):22085-91. Epub 2006 Jun 5.

14.

Chemical modulation of receptor signaling inhibits regenerative angiogenesis in adult zebrafish.

Bayliss PE, Bellavance KL, Whitehead GG, Abrams JM, Aegerter S, Robbins HS, Cowan DB, Keating MT, O'Reilly T, Wood JM, Roberts TM, Chan J.

Nat Chem Biol. 2006 May;2(5):265-73. Epub 2006 Mar 26.

15.

fgf20 is essential for initiating zebrafish fin regeneration.

Whitehead GG, Makino S, Lien CL, Keating MT.

Science. 2005 Dec 23;310(5756):1957-60.

16.

Tissue inhibitor of metalloproteinase 1 regulates matrix metalloproteinase activity during newt limb regeneration.

Stevenson TJ, Vinarsky V, Atkinson DL, Keating MT, Odelberg SJ.

Dev Dyn. 2006 Mar;235(3):606-16.

17.

Generation and characterization of Sca2 (ataxin-2) knockout mice.

Kiehl TR, Nechiporuk A, Figueroa KP, Keating MT, Huynh DP, Pulst SM.

Biochem Biophys Res Commun. 2006 Jan 6;339(1):17-24. Epub 2005 Nov 8.

PMID:
16293225
18.

Heat-shock protein 60 is required for blastema formation and maintenance during regeneration.

Makino S, Whitehead GG, Lien CL, Kim S, Jhawar P, Kono A, Kawata Y, Keating MT.

Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14599-604. Epub 2005 Oct 4.

19.

p38 MAP kinase inhibition enables proliferation of adult mammalian cardiomyocytes.

Engel FB, Schebesta M, Duong MT, Lu G, Ren S, Madwed JB, Jiang H, Wang Y, Keating MT.

Genes Dev. 2005 May 15;19(10):1175-87. Epub 2005 May 3.

20.

Severe arrhythmia disorder caused by cardiac L-type calcium channel mutations.

Splawski I, Timothy KW, Decher N, Kumar P, Sachse FB, Beggs AH, Sanguinetti MC, Keating MT.

Proc Natl Acad Sci U S A. 2005 Jun 7;102(23):8089-96; discussion 8086-8. Epub 2005 Apr 29.

21.

Spectrum and prevalence of cardiac sodium channel variants among black, white, Asian, and Hispanic individuals: implications for arrhythmogenic susceptibility and Brugada/long QT syndrome genetic testing.

Ackerman MJ, Splawski I, Makielski JC, Tester DJ, Will ML, Timothy KW, Keating MT, Jones G, Chadha M, Burrow CR, Stephens JC, Xu C, Judson R, Curran ME.

Heart Rhythm. 2004 Nov;1(5):600-7.

PMID:
15851227
22.

Normal newt limb regeneration requires matrix metalloproteinase function.

Vinarsky V, Atkinson DL, Stevenson TJ, Keating MT, Odelberg SJ.

Dev Biol. 2005 Mar 1;279(1):86-98.

23.

The SRF target gene Fhl2 antagonizes RhoA/MAL-dependent activation of SRF.

Philippar U, Schratt G, Dieterich C, Müller JM, Galgóczy P, Engel FB, Keating MT, Gertler F, Schüle R, Vingron M, Nordheim A.

Mol Cell. 2004 Dec 22;16(6):867-80.

24.

Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism.

Splawski I, Timothy KW, Sharpe LM, Decher N, Kumar P, Bloise R, Napolitano C, Schwartz PJ, Joseph RM, Condouris K, Tager-Flusberg H, Priori SG, Sanguinetti MC, Keating MT.

Cell. 2004 Oct 1;119(1):19-31.

25.

An intronic mutation causes long QT syndrome.

Zhang L, Vincent GM, Baralle M, Baralle FE, Anson BD, Benson DW, Whiting B, Timothy KW, Carlquist J, January CT, Keating MT, Splawski I.

J Am Coll Cardiol. 2004 Sep 15;44(6):1283-91.

26.

Genetic approaches to disease and regeneration.

Keating MT.

Philos Trans R Soc Lond B Biol Sci. 2004 May 29;359(1445):795-8. Review.

27.

Germ cell aneuploidy in zebrafish with mutations in the mitotic checkpoint gene mps1.

Poss KD, Nechiporuk A, Stringer KF, Lee C, Keating MT.

Genes Dev. 2004 Jul 1;18(13):1527-32.

28.

A cardiac arrhythmia syndrome caused by loss of ankyrin-B function.

Mohler PJ, Splawski I, Napolitano C, Bottelli G, Sharpe L, Timothy K, Priori SG, Keating MT, Bennett V.

Proc Natl Acad Sci U S A. 2004 Jun 15;101(24):9137-42. Epub 2004 Jun 3.

29.

The common SCN5A mutation R1193Q causes LQTS-type electrophysiological alterations of the cardiac sodium channel.

Wang Q, Chen S, Chen Q, Wan X, Shen J, Hoeltge GA, Timur AA, Keating MT, Kirsch GE.

J Med Genet. 2004 May;41(5):e66. No abstract available.

30.

Compound mutations: a common cause of severe long-QT syndrome.

Westenskow P, Splawski I, Timothy KW, Keating MT, Sanguinetti MC.

Circulation. 2004 Apr 20;109(15):1834-41. Epub 2004 Mar 29.

PMID:
15051636
31.

Location of mutation in the KCNQ1 and phenotypic presentation of long QT syndrome.

Zareba W, Moss AJ, Sheu G, Kaufman ES, Priori S, Vincent GM, Towbin JA, Benhorin J, Schwartz PJ, Napolitano C, Hall WJ, Keating MT, Qi M, Robinson J, Andrews ML; International LQTS Registry, University of Rochester, Rochester, New York.

J Cardiovasc Electrophysiol. 2003 Nov;14(11):1149-53.

PMID:
14678125
32.

GTF2I hemizygosity implicated in mental retardation in Williams syndrome: genotype-phenotype analysis of five families with deletions in the Williams syndrome region.

Morris CA, Mervis CB, Hobart HH, Gregg RG, Bertrand J, Ensing GJ, Sommer A, Moore CA, Hopkin RJ, Spallone PA, Keating MT, Osborne L, Kimberley KW, Stock AD.

Am J Med Genet A. 2003 Nov 15;123A(1):45-59.

PMID:
14556246
33.
34.

Tales of regeneration in zebrafish.

Poss KD, Keating MT, Nechiporuk A.

Dev Dyn. 2003 Feb;226(2):202-10. Review.

35.

Heart regeneration in zebrafish.

Poss KD, Wilson LG, Keating MT.

Science. 2002 Dec 13;298(5601):2188-90.

36.

A critical role for elastin signaling in vascular morphogenesis and disease.

Karnik SK, Brooke BS, Bayes-Genis A, Sorensen L, Wythe JD, Schwartz RS, Keating MT, Li DY.

Development. 2003 Jan;130(2):411-23.

37.

Mps1 defines a proximal blastemal proliferative compartment essential for zebrafish fin regeneration.

Poss KD, Nechiporuk A, Hillam AM, Johnson SL, Keating MT.

Development. 2002 Nov;129(22):5141-9.

38.

Variant of SCN5A sodium channel implicated in risk of cardiac arrhythmia.

Splawski I, Timothy KW, Tateyama M, Clancy CE, Malhotra A, Beggs AH, Cappuccio FP, Sagnella GA, Kass RS, Keating MT.

Science. 2002 Aug 23;297(5585):1333-6.

39.
40.

Increased risk of arrhythmic events in long-QT syndrome with mutations in the pore region of the human ether-a-go-go-related gene potassium channel.

Moss AJ, Zareba W, Kaufman ES, Gartman E, Peterson DR, Benhorin J, Towbin JA, Keating MT, Priori SG, Schwartz PJ, Vincent GM, Robinson JL, Andrews ML, Feng C, Hall WJ, Medina A, Zhang L, Wang Z.

Circulation. 2002 Feb 19;105(7):794-9.

PMID:
11854117
41.

Metavinculin mutations alter actin interaction in dilated cardiomyopathy.

Olson TM, Illenberger S, Kishimoto NY, Huttelmaier S, Keating MT, Jockusch BM.

Circulation. 2002 Jan 29;105(4):431-7.

PMID:
11815424
42.

Mammalian myotube dedifferentiation induced by newt regeneration extract.

McGann CJ, Odelberg SJ, Keating MT.

Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13699-704.

43.

Long-QT syndrome-associated missense mutations in the pore helix of the HERG potassium channel.

Huang FD, Chen J, Lin M, Keating MT, Sanguinetti MC.

Circulation. 2001 Aug 28;104(9):1071-5.

PMID:
11524404
44.

Molecular and cellular mechanisms of cardiac arrhythmias.

Keating MT, Sanguinetti MC.

Cell. 2001 Feb 23;104(4):569-80. Review. No abstract available.

45.

Dedifferentiation of mammalian myotubes induced by msx1.

Odelberg SJ, Kollhoff A, Keating MT.

Cell. 2000 Dec 22;103(7):1099-109.

46.

Genotype-phenotype correlation in the long-QT syndrome: gene-specific triggers for life-threatening arrhythmias.

Schwartz PJ, Priori SG, Spazzolini C, Moss AJ, Vincent GM, Napolitano C, Denjoy I, Guicheney P, Breithardt G, Keating MT, Towbin JA, Beggs AH, Brink P, Wilde AA, Toivonen L, Zareba W, Robinson JL, Timothy KW, Corfield V, Wattanasirichaigoon D, Corbett C, Haverkamp W, Schulze-Bahr E, Lehmann MH, Schwartz K, Coumel P, Bloise R.

Circulation. 2001 Jan 2;103(1):89-95.

PMID:
11136691
48.

Induction of lef1 during zebrafish fin regeneration.

Poss KD, Shen J, Keating MT.

Dev Dyn. 2000 Oct;219(2):282-6.

49.

Spectrum of mutations in long-QT syndrome genes. KVLQT1, HERG, SCN5A, KCNE1, and KCNE2.

Splawski I, Shen J, Timothy KW, Lehmann MH, Priori S, Robinson JL, Moss AJ, Schwartz PJ, Towbin JA, Vincent GM, Keating MT.

Circulation. 2000 Sep 5;102(10):1178-85.

PMID:
10973849
50.

Impaired distal airway development in mice lacking elastin.

Wendel DP, Taylor DG, Albertine KH, Keating MT, Li DY.

Am J Respir Cell Mol Biol. 2000 Sep;23(3):320-6.

PMID:
10970822

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