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Killer Immunoglobulin-like Receptor-Ligand Interactions Predict Clinical Outcomes Following Unrelated Donor Transplants.

Krieger E, Sabo R, Moezzi S, Cain C, Roberts C, Kimball P, Chesney A, McCarty J, Keating A, Romee R, Wiedl C, Qayyum R, Toor A.

Biol Blood Marrow Transplant. 2019 Oct 29. pii: S1083-8791(19)30673-1. doi: 10.1016/j.bbmt.2019.10.016. [Epub ahead of print]


Comprehensive Prognostication in Critically Ill Pediatric Hematopoietic Cell Transplant Patients: Results from Merging the Center for International Blood and Marrow Transplant Research (CIBMTR) and Virtual Pediatric Systems (VPS) Registries.

Zinter MS, Logan BR, Fretham C, Sapru A, Abraham A, Aljurf MD, Arnold SD, Artz A, Auletta JJ, Chhabra S, Copelan E, Duncan C, Gale RP, Guinan E, Hematti P, Keating AK, Marks DI, Olsson R, Savani BN, Ustun C, Williams KM, Pasquini MC, Dvorak CC.

Biol Blood Marrow Transplant. 2019 Sep 26. pii: S1083-8791(19)30638-X. doi: 10.1016/j.bbmt.2019.09.027. [Epub ahead of print]


The impact of dietary supplementation of arginine during gestation in a commercial swine herd: II. Offspring performance.

Hines EA, Romoser MR, Kiefer ZE, Keating AF, Baumgard LH, Niemi J, Haberl B, Williams NH, Kerr BJ, Touchette KJ, Ross JW.

J Anim Sci. 2019 Sep 3;97(9):3626-3635. doi: 10.1093/jas/skz214.


Ataxia Telangiectasia Mutated coordinates the ovarian DNA repair and atresia-initiating response to phosphoramide mustard.

Clark KL, Keating AF.

Biol Reprod. 2019 Aug 22. pii: ioz160. doi: 10.1093/biolre/ioz160. [Epub ahead of print]


Antibody Therapies for Acute Myeloid Leukemia: Unconjugated, Toxin-Conjugated, Radio-Conjugated and Multivalent Formats.

Williams BA, Law A, Hunyadkurti J, Desilets S, Leyton JV, Keating A.

J Clin Med. 2019 Aug 20;8(8). pii: E1261. doi: 10.3390/jcm8081261. Review.


Heat stress during the luteal phase decreases luteal size but does not affect circulating progesterone in gilts1.

Bidne KL, Romoser MR, Ross JW, Baumgard LH, Keating AF.

J Anim Sci. 2019 Oct 3;97(10):4314-4322. doi: 10.1093/jas/skz251.


The impact of dietary supplementation of arginine during gestation in a commercial swine herd: I. Gilt reproductive performance.

Hines EA, Romoser MR, Kiefer ZE, Keating AF, Baumgard LH, Niemi J, Gabler NK, Patience JF, Haberl B, Williams NH, Kerr BJ, Touchette KJ, Ross JW.

J Anim Sci. 2019 Sep 3;97(9):3617-3625. doi: 10.1093/jas/skz233.


Combining gene mutation with gene expression analysis improves outcome prediction in acute promyelocytic leukemia.

Lucena-Araujo AR, Coelho-Silva JL, Pereira-Martins DA, Silveira DR, Koury LC, Melo RAM, Bittencourt R, Pagnano K, Pasquini R, Nunes EC, Fagundes EM, Gloria AB, Kerbauy F, de Lourdes Chauffaille M, Bendit I, Rocha V, Keating A, Tallman MS, Ribeiro RC, Dillon R, Ganser A, Löwenberg B, Valk PJM, Lo-Coco F, Sanz MA, Berliner N, Rego EM.

Blood. 2019 Sep 19;134(12):951-959. doi: 10.1182/blood.2019000239. Epub 2019 Jul 10.


Developmental Origins of Ovarian Disorder: Impact of Maternal Lean Gestational Diabetes on the Offspring Ovarian Proteome in Mice.

Clark KL, Talton OO, Ganesan S, Schulz LC, Keating AF.

Biol Reprod. 2019 Jul 10. pii: ioz116. doi: 10.1093/biolre/ioz116. [Epub ahead of print]


Atomic force microscopy with integrated on-chip interferometric readout.

Zawierta M, Jeffery RD, Putrino G, Silva KKMBD, Keating A, Martyniuk M, Faraone L.

Ultramicroscopy. 2019 Oct;205:75-83. doi: 10.1016/j.ultramic.2019.05.011. Epub 2019 May 25.


Reducing minimal residual disease with blinatumomab prior to HCT for pediatric patients with acute lymphoblastic leukemia.

Keating AK, Gossai N, Phillips CL, Maloney K, Campbell K, Doan A, Bhojwani D, Burke MJ, Verneris MR.

Blood Adv. 2019 Jul 9;3(13):1926-1929. doi: 10.1182/bloodadvances.2018025726. No abstract available.


Banking Mesenchymal Stromal Cells from Umbilical Cord Tissue: Large Sample Size Analysis Reveals Consistency Between Donors.

Raileanu VN, Whiteley J, Chow T, Kollara A, Mohamed A, Keating A, Rogers IM.

Stem Cells Transl Med. 2019 Oct;8(10):1041-1054. doi: 10.1002/sctm.19-0022. Epub 2019 Jun 20.


Hyperhydration is not necessary for high-dose melphalan in stem cell transplantation.

Nakagaki M, Button E, Keating A, Marsh J, Mitchell C, Birchley A, Kennedy GA.

Bone Marrow Transplant. 2019 Jun 11. doi: 10.1038/s41409-019-0586-1. [Epub ahead of print] No abstract available.


Differential Immunomodulatory Effects of Human Bone Marrow-Derived Mesenchymal Stromal Cells on Natural Killer Cells.

Hu CD, Kosaka Y, Marcus P, Rashedi I, Keating A.

Stem Cells Dev. 2019 Jul 15;28(14):933-943. doi: 10.1089/scd.2019.0059. Epub 2019 Jun 24.


Exosomes secreted by mesenchymal stromal/stem cell-derived adipocytes promote breast cancer cell growth via activation of Hippo signaling pathway.

Wang S, Su X, Xu M, Xiao X, Li X, Li H, Keating A, Zhao RC.

Stem Cell Res Ther. 2019 Apr 11;10(1):117. doi: 10.1186/s13287-019-1220-2.


Bone Marrow Mesenchymal Stromal Cell Treatment in Patients with Osteoarthritis Results in Overall Improvement in Pain and Symptoms and Reduces Synovial Inflammation.

Chahal J, Gómez-Aristizábal A, Shestopaloff K, Bhatt S, Chaboureau A, Fazio A, Chisholm J, Weston A, Chiovitti J, Keating A, Kapoor M, Ogilvie-Harris DJ, Syed KA, Gandhi R, Mahomed NN, Marshall KW, Sussman MS, Naraghi AM, Viswanathan S.

Stem Cells Transl Med. 2019 Aug;8(8):746-757. doi: 10.1002/sctm.18-0183. Epub 2019 Apr 9.


The influence of stem cell source on transplant outcomes for pediatric patients with acute myeloid leukemia.

Keating AK, Langenhorst J, Wagner JE, Page KM, Veys P, Wynn RF, Stefanski H, Elfeky R, Giller R, Mitchell R, Milano F, O'Brien TA, Dahlberg A, Delaney C, Kurtzberg J, Verneris MR, Boelens JJ.

Blood Adv. 2019 Apr 9;3(7):1118-1128. doi: 10.1182/bloodadvances.2018025908.


Cell Therapy for Knee Osteoarthritis: Mesenchymal Stromal Cells.

Kim C, Keating A.

Gerontology. 2019;65(3):294-298. doi: 10.1159/000496605. Epub 2019 Mar 21. Review.


Survival Trends in Infants Undergoing Allogeneic Hematopoietic Cell Transplant.

Parikh SH, Satwani P, Ahn KW, Sahr NA, Fretham C, Abraham AA, Agrawal V, Auletta JJ, Abdel-Azim H, Copelan E, Diaz MA, Dvorak CC, Frangoul HA, Freytes CO, Gadalla SM, Gale RP, George B, Gergis U, Hashmi S, Hematti P, Hildebrandt GC, Keating AK, Lazarus HM, Myers KC, Olsson RF, Prestidge T, Rotz SJ, Savani BN, Shereck EB, Williams KM, Wirk B, Pasquini MC, Loren AW.

JAMA Pediatr. 2019 May 1;173(5):e190081. doi: 10.1001/jamapediatrics.2019.0081. Epub 2019 May 6.


Safety and feasibility of outpatient autologous stem cell transplantation in pediatric patients with primary central nervous system tumors.

Koo J, Silverman S, Nuechterlein B, Keating AK, Verneris MR, Foreman NK, Mulcahy Levy JM.

Bone Marrow Transplant. 2019 Oct;54(10):1605-1613. doi: 10.1038/s41409-019-0479-3. Epub 2019 Feb 19.


Tertiary Structural Motif Sequence Statistics Enable Facile Prediction and Design of Peptides that Bind Anti-apoptotic Bfl-1 and Mcl-1.

Frappier V, Jenson JM, Zhou J, Grigoryan G, Keating AE.

Structure. 2019 Apr 2;27(4):606-617.e5. doi: 10.1016/j.str.2019.01.008. Epub 2019 Feb 14.


Taurine alleviates repression of betaine-homocysteine S-methyltransferase and significantly improves the efficacy of long-term betaine treatment in a mouse model of cystathionine β-synthase-deficient homocystinuria.

Maclean KN, Jiang H, Phinney WN, Keating AK, Hurt KJ, Stabler SP.

FASEB J. 2019 May;33(5):6339-6353. doi: 10.1096/fj.201802069RR. Epub 2019 Feb 15.


Impacts of chronic and increasing lipopolysaccharide exposure on production and reproductive parameters in lactating Holstein dairy cows.

Dickson MJ, Kvidera SK, Horst EA, Wiley CE, Mayorga EJ, Ydstie J, Perry GA, Baumgard LH, Keating AF.

J Dairy Sci. 2019 Apr;102(4):3569-3583. doi: 10.3168/jds.2018-15631. Epub 2019 Feb 7.


Malglycemia is associated with poor outcomes in pediatric and adolescent hematopoietic stem cell transplant patients.

Sopfe J, Pyle L, Keating AK, Campbell K, Liu AK, Wadwa RP, Verneris MR, Giller RH, Forlenza GP.

Blood Adv. 2019 Feb 12;3(3):350-359. doi: 10.1182/bloodadvances.2018021014.


T Cell Repertoire Evolution after Allogeneic Bone Marrow Transplantation: An Organizational Perspective.

Meier JA, Haque M, Fawaz M, Abdeen H, Coffey D, Towlerton A, Abdeen A, Toor A, Warren E, Reed J, Kanakry CG, Keating A, Luznik L, Toor AA.

Biol Blood Marrow Transplant. 2019 May;25(5):868-882. doi: 10.1016/j.bbmt.2019.01.021. Epub 2019 Jan 21.


Effects of continuous and increasing lipopolysaccharide infusion on basal and stimulated metabolism in lactating Holstein cows.

Horst EA, Kvidera SK, Dickson MJ, McCarthy CS, Mayorga EJ, Al-Qaisi M, Ramirez HA, Keating AF, Baumgard LH.

J Dairy Sci. 2019 Apr;102(4):3584-3597. doi: 10.3168/jds.2018-15627. Epub 2019 Jan 17.


Humanized anti-CD123 antibody facilitates NK cell antibody-dependent cell-mediated cytotoxicity (ADCC) of Hodgkin lymphoma targets via ARF6/PLD-1.

Ernst D, Williams BA, Wang XH, Yoon N, Kim KP, Chiu J, Luo ZJ, Hermans KG, Krueger J, Keating A.

Blood Cancer J. 2019 Jan 15;9(2):6. doi: 10.1038/s41408-018-0168-2.


Engineering of Nanofibrous Amorphous and Crystalline Solid Dispersions for Oral Drug Delivery.

Modica de Mohac L, Keating AV, de Fátima Pina M, Raimi-Abraham BT.

Pharmaceutics. 2018 Dec 24;11(1). pii: E7. doi: 10.3390/pharmaceutics11010007. Review.


The effect of recovery from heat stress on circulating bioenergetics and inflammatory biomarkers.

Abuajamieh M, Kvidera SK, Mayorga EJ, Kaiser A, Lei S, Seibert JT, Horst EA, Sanz Fernandez MV, Ross JW, Selsby JT, Keating AF, Rhoads RP, Baumgard LH.

J Anim Sci. 2018 Nov 21;96(11):4599-4610. doi: 10.1093/jas/sky345.


Peptide design by optimization on a data-parameterized protein interaction landscape.

Jenson JM, Xue V, Stretz L, Mandal T, Reich LL, Keating AE.

Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):E10342-E10351. doi: 10.1073/pnas.1812939115. Epub 2018 Oct 15.


Generation of Functional Hepatocytes from Human Adipose-Derived MYC+ KLF4+ GMNN+ Stem Cells Analyzed by Single-Cell RNA-Seq Profiling.

Li H, Zhu L, Chen H, Li T, Han Q, Wang S, Yao X, Feng H, Fan L, Gao S, Boyd R, Cao X, Zhu P, Li J, Keating A, Su X, Zhao RC.

Stem Cells Transl Med. 2018 Nov;7(11):792-805. doi: 10.1002/sctm.17-0273. Epub 2018 Sep 11.


Rats can predict aversiveness of Active Pharmaceutical Ingredients.

Soto J, Keeley A, Keating AV, Mohamed-Ahmed AHA, Sheng Y, Winzenburg G, Turner R, Desset-Brèthes S, Orlu M, Tuleu C.

Eur J Pharm Biopharm. 2018 Dec;133:77-84. doi: 10.1016/j.ejpb.2018.09.027. Epub 2018 Sep 27.


Effects of zinc amino acid complex on biomarkers of gut integrity and metabolism during and following heat stress or feed restriction in pigs.

Mayorga EJ, Kvidera SK, Horst EA, Al-Qaisi M, Dickson MJ, Seibert JT, Lei S, Keating AF, Ross JW, Rhoads RP, Rambo ZJ, Wilson ME, Baumgard LH.

J Anim Sci. 2018 Sep 29;96(10):4173-4185. doi: 10.1093/jas/sky293.


PixelDB: Protein-peptide complexes annotated with structural conservation of the peptide binding mode.

Frappier V, Duran M, Keating AE.

Protein Sci. 2018 Aug;27(8):1535-1537. doi: 10.1002/pro.3431. No abstract available.


Concise Review: TLR Pathway-miRNA Interplay in Mesenchymal Stromal Cells: Regulatory Roles and Therapeutic Directions.

Abdi J, Rashedi I, Keating A.

Stem Cells. 2018 Nov;36(11):1655-1662. doi: 10.1002/stem.2902. Epub 2018 Oct 13. Review.


Human mesenchymal stromal cells do not promote recurrence of soft tissue sarcomas in mouse xenografts after radiation and surgery.

Filomeno PA, Kim KP, Yoon N, Rashedi I, Dayan V, Kandel RA, Wang XH, Felizardo TC, Berinstein E, Jelveh S, Filomeno A, Medin JA, Ferguson PC, Keating A.

Cytotherapy. 2018 Aug;20(8):1001-1012. doi: 10.1016/j.jcyt.2018.05.011. Epub 2018 Jul 31.


Impact of toxicant exposures on ovarian gap junctions.

Clark KL, Ganesan S, Keating AF.

Reprod Toxicol. 2018 Oct;81:140-146. doi: 10.1016/j.reprotox.2018.07.087. Epub 2018 Jul 26. Review.


Impact of repeated lipopolysaccharide administration on ovarian signaling during the follicular phase of the estrous cycle in post-pubertal pigs.

Bidne KL, Kvidera SS, Ross JW, Baumgard LH, Keating AF.

J Anim Sci. 2018 Jul 3. doi: 10.1093/jas/sky226. [Epub ahead of print]


CD16+NK-92 and anti-CD123 monoclonal antibody prolongs survival in primary human acute myeloid leukemia xenografted mice.

Williams BA, Wang XH, Leyton JV, Maghera S, Deif B, Reilly RM, Minden MD, Keating A.

Haematologica. 2018 Oct;103(10):1720-1729. doi: 10.3324/haematol.2017.187385. Epub 2018 Jul 5.


Outcomes of Measurable Residual Disease in Pediatric Acute Myeloid Leukemia before and after Hematopoietic Stem Cell Transplant: Validation of Difference from Normal Flow Cytometry with Chimerism Studies and Wilms Tumor 1 Gene Expression.

Jacobsohn DA, Loken MR, Fei M, Adams A, Brodersen LE, Logan BR, Ahn KW, Shaw BE, Kletzel M, Olszewski M, Khan S, Meshinchi S, Keating A, Harris A, Teira P, Duerst RE, Margossian SP, Martin PL, Petrovic A, Dvorak CC, Nemecek ER, Boyer MW, Chen AR, Davis JH, Shenoy S, Savasan S, Hudspeth MP, Adams RH, Lewis VA, Kheradpour A, Kasow KA, Gillio AP, Haight AE, Bhatia M, Bambach BJ, Haines HL, Quigg TC, Greiner RJ, Talano JM, Delgado DC, Cheerva A, Gowda M, Ahuja S, Ozkaynak M, Mitchell D, Schultz KR, Fry TJ, Loeb DM, Pulsipher MA.

Biol Blood Marrow Transplant. 2018 Oct;24(10):2040-2046. doi: 10.1016/j.bbmt.2018.06.010. Epub 2018 Jun 19.


Beyond maximum grade: modernising the assessment and reporting of adverse events in haematological malignancies.

Thanarajasingam G, Minasian LM, Baron F, Cavalli F, De Claro RA, Dueck AC, El-Galaly TC, Everest N, Geissler J, Gisselbrecht C, Gribben J, Horowitz M, Ivy SP, Jacobson CA, Keating A, Kluetz PG, Krauss A, Kwong YL, Little RF, Mahon FX, Matasar MJ, Mateos MV, McCullough K, Miller RS, Mohty M, Moreau P, Morton LM, Nagai S, Rule S, Sloan J, Sonneveld P, Thompson CA, Tzogani K, van Leeuwen FE, Velikova G, Villa D, Wingard JR, Wintrich S, Seymour JF, Habermann TM.

Lancet Haematol. 2018 Nov;5(11):e563-e598. doi: 10.1016/S2352-3026(18)30051-6. Epub 2018 Jun 18. Review. Erratum in: Lancet Haematol. 2019 Mar;6(3):e121.


Exosomes released by hepatocarcinoma cells endow adipocytes with tumor-promoting properties.

Wang S, Xu M, Li X, Su X, Xiao X, Keating A, Zhao RC.

J Hematol Oncol. 2018 Jun 14;11(1):82. doi: 10.1186/s13045-018-0625-1.


Characterizing the acute heat stress response in gilts: II. Assessing repeatability and association with fertility.

Graves KL, Seibert JT, Keating AF, Baumgard LH, Ross JW.

J Anim Sci. 2018 Jun 4;96(6):2419-2426. doi: 10.1093/jas/skx037.


Targeting MUC1-C suppresses BCL2A1 in triple-negative breast cancer.

Hiraki M, Maeda T, Mehrotra N, Jin C, Alam M, Bouillez A, Hata T, Tagde A, Keating A, Kharbanda S, Singh H, Kufe D.

Signal Transduct Target Ther. 2018 May 12;3:13. doi: 10.1038/s41392-018-0013-x. eCollection 2018.


Topical Application of Culture-Expanded CD34+ Umbilical Cord Blood Cells from Frozen Units Accelerates Healing of Diabetic Skin Wounds in Mice.

Whiteley J, Chow T, Adissu H, Keating A, Rogers IM.

Stem Cells Transl Med. 2018 Aug;7(8):591-601. doi: 10.1002/sctm.17-0302. Epub 2018 May 12.


Impact of heat stress during the follicular phase on porcine ovarian steroidogenic and phosphatidylinositol-3 signaling.

Dickson MJ, Hager CL, Al-Shaibi A, Thomas PQ, Baumgard LH, Ross JW, Keating AF.

J Anim Sci. 2018 Jun 4;96(6):2162-2174. doi: 10.1093/jas/sky144.


Characterization of the acute heat stress response in gilts: III. Genome-wide association studies of thermotolerance traits in pigs.

Kim KS, Seibert JT, Edea Z, Graves KL, Kim ES, Keating AF, Baumgard LH, Ross JW, Rothschild MF.

J Anim Sci. 2018 Jun 4;96(6):2074-2085. doi: 10.1093/jas/sky131.


Characterizing the acute heat stress response in gilts: I. Thermoregulatory and production variables.

Seibert JT, Graves KL, Hale BJ, Keating AF, Baumgard LH, Ross JW.

J Anim Sci. 2018 Apr 3;96(3):941-949. doi: 10.1093/jas/skx036.


Effect of chromium on bioenergetics and leukocyte dynamics following immunoactivation in lactating Holstein cows.

Horst EA, Kvidera SK, Mayorga EJ, Shouse CS, Al-Qaisi M, Dickson MJ, Ydstie J, Ramirez Ramirez HA, Keating AF, Dickson DJ, Griswold KE, Baumgard LH.

J Dairy Sci. 2018 Jun;101(6):5515-5530. doi: 10.3168/jds.2017-13899. Epub 2018 Mar 15.


Clozapine Patients at the Interface between Primary and Secondary Care.

Barrett M, Keating A, Lynch D, Scanlon G, Kigathi M, Corcoran F, Sahm LJ.

Pharmacy (Basel). 2018 Feb 26;6(1). pii: E19. doi: 10.3390/pharmacy6010019.

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