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Items: 36


Natural Killer Cells Suppress T Cell-Associated Tumor Immune Evasion.

Freeman AJ, Vervoort SJ, Ramsbottom KM, Kelly MJ, Michie J, Pijpers L, Johnstone RW, Kearney CJ, Oliaro J.

Cell Rep. 2019 Sep 10;28(11):2784-2794.e5. doi: 10.1016/j.celrep.2019.08.017.


Physical Structuring of Injectable Polymeric Systems to Controllably Deliver Nanosized Extracellular Vesicles.

Nikravesh N, Davies OG, Azoidis I, Moakes RJA, Marani L, Turner M, Kearney CJ, Eisenstein NM, Grover LM, Cox SC.

Adv Healthc Mater. 2019 May;8(9):e1801604. doi: 10.1002/adhm.201801604. Epub 2019 Mar 6.


Protection from EAE in DOCK8 mutant mice occurs despite increased Th17 cell frequencies in the periphery.

Wilson AS, Law HD, Knobbe-Thomsen CB, Kearney CJ, Oliaro J, Binsfeld C, Burgio G, Starrs L, Brenner D, Randall KL, Brüstle A.

Eur J Immunol. 2019 May;49(5):770-781. doi: 10.1002/eji.201847960. Epub 2019 Feb 20.


Collagen scaffolds functionalised with copper-eluting bioactive glass reduce infection and enhance osteogenesis and angiogenesis both in vitro and in vivo.

Ryan EJ, Ryan AJ, González-Vázquez A, Philippart A, Ciraldo FE, Hobbs C, Nicolosi V, Boccaccini AR, Kearney CJ, O'Brien FJ.

Biomaterials. 2019 Mar;197:405-416. doi: 10.1016/j.biomaterials.2019.01.031. Epub 2019 Jan 23.


Antagonism of IAPs Enhances CAR T-cell Efficacy.

Michie J, Beavis PA, Freeman AJ, Vervoort SJ, Ramsbottom KM, Narasimhan V, Lelliott EJ, Lalaoui N, Ramsay RG, Johnstone RW, Silke J, Darcy PK, Voskoboinik I, Kearney CJ, Oliaro J.

Cancer Immunol Res. 2019 Feb;7(2):183-192. doi: 10.1158/2326-6066.CIR-18-0428. Epub 2019 Jan 16.


Platelet-derived growth factor stabilises vascularisation in collagen-glycosaminoglycan scaffolds in vitro.

do Amaral RJFC, Cavanagh B, O'Brien FJ, Kearney CJ.

J Tissue Eng Regen Med. 2019 Feb;13(2):261-273. doi: 10.1002/term.2789. Epub 2019 Jan 24.


Tumor immune evasion arises through loss of TNF sensitivity.

Kearney CJ, Vervoort SJ, Hogg SJ, Ramsbottom KM, Freeman AJ, Lalaoui N, Pijpers L, Michie J, Brown KK, Knight DA, Sutton V, Beavis PA, Voskoboinik I, Darcy PK, Silke J, Trapani JA, Johnstone RW, Oliaro J.

Sci Immunol. 2018 May 18;3(23). pii: eaar3451. doi: 10.1126/sciimmunol.aar3451.


Mind Bomb Regulates Cell Death during TNF Signaling by Suppressing RIPK1's Cytotoxic Potential.

Feltham R, Jamal K, Tenev T, Liccardi G, Jaco I, Domingues CM, Morris O, John SW, Annibaldi A, Widya M, Kearney CJ, Clancy D, Elliott PR, Glatter T, Qiao Q, Thompson AJ, Nesvizhskii A, Schmidt A, Komander D, Wu H, Martin S, Meier P.

Cell Rep. 2018 Apr 10;23(2):470-484. doi: 10.1016/j.celrep.2018.03.054.


Electroconductive Biohybrid Collagen/Pristine Graphene Composite Biomaterials with Enhanced Biological Activity.

Ryan AJ, Kearney CJ, Shen N, Khan U, Kelly AG, Probst C, Brauchle E, Biccai S, Garciarena CD, Vega-Mayoral V, Loskill P, Kerrigan SW, Kelly DJ, Schenke-Layland K, Coleman JN, O'Brien FJ.

Adv Mater. 2018 Apr;30(15):e1706442. doi: 10.1002/adma.201706442. Epub 2018 Mar 5.


Staphylococcal Osteomyelitis: Disease Progression, Treatment Challenges, and Future Directions.

Kavanagh N, Ryan EJ, Widaa A, Sexton G, Fennell J, O'Rourke S, Cahill KC, Kearney CJ, O'Brien FJ, Kerrigan SW.

Clin Microbiol Rev. 2018 Feb 14;31(2). pii: e00084-17. doi: 10.1128/CMR.00084-17. Print 2018 Apr. Review.


Infrapatellar Fat Pad Stem Cells: From Developmental Biology to Cell Therapy.

do Amaral RJFC, Almeida HV, Kelly DJ, O'Brien FJ, Kearney CJ.

Stem Cells Int. 2017;2017:6843727. doi: 10.1155/2017/6843727. Epub 2017 Sep 6. Review.


DOCK8 Drives Src-Dependent NK Cell Effector Function.

Kearney CJ, Vervoort SJ, Ramsbottom KM, Freeman AJ, Michie J, Peake J, Casanova JL, Picard C, Tangye SG, Ma CS, Johnstone RW, Randall KL, Oliaro J.

J Immunol. 2017 Aug 9. pii: ji1700751. doi: 10.4049/jimmunol.1700751. [Epub ahead of print]


PD-L1 and IAPs co-operate to protect tumors from cytotoxic lymphocyte-derived TNF.

Kearney CJ, Lalaoui N, Freeman AJ, Ramsbottom KM, Silke J, Oliaro J.

Cell Death Differ. 2017 Oct;24(10):1705-1716. doi: 10.1038/cdd.2017.94. Epub 2017 Jun 30.


DOCK8 regulates signal transduction events to control immunity.

Kearney CJ, Randall KL, Oliaro J.

Cell Mol Immunol. 2017 May;14(5):406-411. doi: 10.1038/cmi.2017.9. Epub 2017 Apr 3. Review.


An Inflammatory Perspective on Necroptosis.

Kearney CJ, Martin SJ.

Mol Cell. 2017 Mar 16;65(6):965-973. doi: 10.1016/j.molcel.2017.02.024. Review.


Loss of DNAM-1 ligand expression by acute myeloid leukemia cells renders them resistant to NK cell killing.

Kearney CJ, Ramsbottom KM, Voskoboinik I, Darcy PK, Oliaro J.

Oncoimmunology. 2016 Jun 27;5(8):e1196308. doi: 10.1080/2162402X.2016.1196308. eCollection 2016 Aug.


DNA Origami: Folded DNA-Nanodevices That Can Direct and Interpret Cell Behavior.

Kearney CJ, Lucas CR, O'Brien FJ, Castro CE.

Adv Mater. 2016 Jul;28(27):5509-24. doi: 10.1002/adma.201504733. Epub 2016 Feb 3. Review.


The Role of the immunological Synapse Formed by Cytotoxic Lymphocytes in Immunodeficiency and Anti-Tumor immunity.

Kearney CJ, Brennan AJ, Darcy PK, Oliaro J.

Crit Rev Immunol. 2015;35(4):325-47. Review.


Special Collection: Closing the Gaps in Skin Wound Healing.

Kearney CJ, Pandit A.

Tissue Eng Part A. 2016 Mar;22(5-6):401-2. doi: 10.1089/ten.TEA.2015.0549. Epub 2016 Jan 15. No abstract available.


A chromatin-independent role of Polycomb-like 1 to stabilize p53 and promote cellular quiescence.

Brien GL, Healy E, Jerman E, Conway E, Fadda E, O'Donovan D, Krivtsov AV, Rice AM, Kearney CJ, Flaus A, McDade SS, Martin SJ, McLysaght A, O'Connell DJ, Armstrong SA, Bracken AP.

Genes Dev. 2015 Nov 1;29(21):2231-43. doi: 10.1101/gad.267930.115. Epub 2015 Oct 22.


Switchable Release of Entrapped Nanoparticles from Alginate Hydrogels.

Kearney CJ, Skaat H, Kennedy SM, Hu J, Darnell M, Raimondo TM, Mooney DJ.

Adv Healthc Mater. 2015 Aug 5;4(11):1634-1639. doi: 10.1002/adhm.201500254. Epub 2015 Jun 5.


Diverse Activators of the NLRP3 Inflammasome Promote IL-1β Secretion by Triggering Necrosis.

Cullen SP, Kearney CJ, Clancy DM, Martin SJ.

Cell Rep. 2015 Jun 16;11(10):1535-48. doi: 10.1016/j.celrep.2015.05.003. Epub 2015 May 28.


Necroptosis suppresses inflammation via termination of TNF- or LPS-induced cytokine and chemokine production.

Kearney CJ, Cullen SP, Tynan GA, Henry CM, Clancy D, Lavelle EC, Martin SJ.

Cell Death Differ. 2015 Aug;22(8):1313-27. doi: 10.1038/cdd.2014.222. Epub 2015 Jan 23.


Three-dimensional human tissue models that incorporate diabetic foot ulcer-derived fibroblasts mimic in vivo features of chronic wounds.

Maione AG, Brudno Y, Stojadinovic O, Park LK, Smith A, Tellechea A, Leal EC, Kearney CJ, Veves A, Tomic-Canic M, Mooney DJ, Garlick JA.

Tissue Eng Part C Methods. 2015 May;21(5):499-508. doi: 10.1089/ten.TEC.2014.0414. Epub 2015 Mar 31.


RIPK1 can function as an inhibitor rather than an initiator of RIPK3-dependent necroptosis.

Kearney CJ, Cullen SP, Clancy D, Martin SJ.

FEBS J. 2014 Nov;281(21):4921-34. doi: 10.1111/febs.13034. Epub 2014 Oct 4.


Inflammatory outcomes of apoptosis, necrosis and necroptosis.

Davidovich P, Kearney CJ, Martin SJ.

Biol Chem. 2014 Oct;395(10):1163-71. doi: 10.1515/hsz-2014-0164. Review.


Refilling drug delivery depots through the blood.

Brudno Y, Silva EA, Kearney CJ, Lewin SA, Miller A, Martinick KD, Aizenberg M, Mooney DJ.

Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12722-7. doi: 10.1073/pnas.1413027111. Epub 2014 Aug 19.


Ultrasound-triggered disruption and self-healing of reversibly cross-linked hydrogels for drug delivery and enhanced chemotherapy.

Huebsch N, Kearney CJ, Zhao X, Kim J, Cezar CA, Suo Z, Mooney DJ.

Proc Natl Acad Sci U S A. 2014 Jul 8;111(27):9762-7. doi: 10.1073/pnas.1405469111. Epub 2014 Jun 24.


Macroscale delivery systems for molecular and cellular payloads.

Kearney CJ, Mooney DJ.

Nat Mater. 2013 Nov;12(11):1004-17. doi: 10.1038/nmat3758. Review.


Competition for growth factors: a lot more death with a little less Aktion.

Kearney CJ, Martin SJ.

Cell Death Differ. 2013 Oct;20(10):1291-2. doi: 10.1038/cdd.2013.99. No abstract available.


Fas/CD95-induced chemokines can serve as "find-me" signals for apoptotic cells.

Cullen SP, Henry CM, Kearney CJ, Logue SE, Feoktistova M, Tynan GA, Lavelle EC, Leverkus M, Martin SJ.

Mol Cell. 2013 Mar 28;49(6):1034-48. doi: 10.1016/j.molcel.2013.01.025. Epub 2013 Feb 21.


Inhibitor of apoptosis proteins (IAPs) and their antagonists regulate spontaneous and tumor necrosis factor (TNF)-induced proinflammatory cytokine and chemokine production.

Kearney CJ, Sheridan C, Cullen SP, Tynan GA, Logue SE, Afonina IS, Vucic D, Lavelle EC, Martin SJ.

J Biol Chem. 2013 Feb 15;288(7):4878-90. doi: 10.1074/jbc.M112.422410. Epub 2012 Dec 28.


The use of extracorporeal shock wave-stimulated periosteal cells for orthotopic bone generation.

Kearney CJ, Hsu HP, Spector M.

Tissue Eng Part A. 2012 Jul;18(13-14):1500-8. doi: 10.1089/ten.TEA.2011.0573. Epub 2012 Jun 4.


Extracorporeal shockwave-induced expression of lubricin in tendons and septa.

Zhang D, Kearney CJ, Cheriyan T, Schmid TM, Spector M.

Cell Tissue Res. 2011 Nov;346(2):255-62. doi: 10.1007/s00441-011-1258-7. Epub 2011 Oct 19.


Extracorporeal shock wave-induced proliferation of periosteal cells.

Kearney CJ, Lee JY, Padera RF, Hsu HP, Spector M.

J Orthop Res. 2011 Oct;29(10):1536-43. doi: 10.1002/jor.21346. Epub 2011 Mar 29.


New Jersey Caucasian, African American, and Hispanic population data on the PCR-based loci HLA-DQA1, LDLR, GYPA, HBGG, D7S8, and Gc.

Jankowski LB, Budowle B, Swec NT, Pino JA, Freck-Tootell S, Corey HW, Schwartz R, LaRue EJ, Rochin WL, Kearney CJ, Tarver ML.

J Forensic Sci. 1998 Sep;43(5):1037-40.


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