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Items: 1 to 50 of 273

1.

Quantitative assessment of left atrial scar using high-density voltage mapping and a novel automated voltage analysis tool.

Herczeg S, Walsh K, Keaney JJ, Keelan E, Travers J, Szeplaki G, Galvin J.

J Interv Card Electrophysiol. 2019 Jun 5. doi: 10.1007/s10840-019-00570-7. [Epub ahead of print]

PMID:
31165967
2.

The management of cardiac implantable electronic device lead perforations: a multicentre study.

Rav Acha M, Rafael A, Keaney JJ, Elitzur Y, Danon A, Shauer A, Taha L, Shechter Y, Bogot NR, Luria D, Ilan M, Singh SM, Mela T, Weisz G, Glikson M, Medina A.

Europace. 2019 Jun 1;21(6):937-943. doi: 10.1093/europace/euz120.

PMID:
31157389
3.

Exercise Rescues Gene Pathways Involved in Vascular Expansion and Promotes Functional Angiogenesis in Subcutaneous White Adipose Tissue.

Min SY, Learnard H, Kant S, Gealikman O, Rojas-Rodriguez R, DeSouza T, Desai A, Keaney JF Jr, Corvera S, Craige SM.

Int J Mol Sci. 2019 Apr 25;20(8). pii: E2046. doi: 10.3390/ijms20082046.

4.

Heart rate, mortality, and the relation with clinical and subclinical cardiovascular diseases: results from the Gutenberg Health Study.

Münzel T, Hahad O, Gori T, Hollmann S, Arnold N, Prochaska JH, Schulz A, Beutel M, Pfeiffer N, Schmidtmann I, Lackner KJ, Keaney JF Jr, Wild PS.

Clin Res Cardiol. 2019 Apr 5. doi: 10.1007/s00392-019-01466-2. [Epub ahead of print]

PMID:
30953178
5.

Inhibition of Bruton's Tyrosine Kinase Modulates Microglial Phagocytosis: Therapeutic Implications for Alzheimer's Disease.

Keaney J, Gasser J, Gillet G, Scholz D, Kadiu I.

J Neuroimmune Pharmacol. 2019 Feb 13. doi: 10.1007/s11481-019-09839-0. [Epub ahead of print]

PMID:
30758770
6.

Age-related changes in eye morphology and aqueous humor dynamics in DBA/2J mice using contrast-enhanced ocular MRI.

Crosbie DE, Keaney J, Tam LCS, Daniel Stamer W, Campbell M, Humphries P.

Magn Reson Imaging. 2019 Jun;59:10-16. doi: 10.1016/j.mri.2019.01.016. Epub 2019 Jan 17.

PMID:
30660703
7.

Short-term exposure to ambient air pollution and circulating biomarkers of endothelial cell activation: The Framingham Heart Study.

Li W, Dorans KS, Wilker EH, Rice MB, Ljungman PL, Schwartz JD, Coull BA, Koutrakis P, Gold DR, Keaney JF Jr, Vasan RS, Benjamin EJ, Mittleman MA.

Environ Res. 2019 Apr;171:36-43. doi: 10.1016/j.envres.2018.10.027. Epub 2018 Oct 28.

PMID:
30654247
8.

Endothelial α1AMPK modulates angiotensin II-mediated vascular inflammation and dysfunction.

Kröller-Schön S, Jansen T, Tran TLP, Kvandová M, Kalinovic S, Oelze M, Keaney JF Jr, Foretz M, Viollet B, Daiber A, Kossmann S, Lagrange J, Frenis K, Wenzel P, Münzel T, Schulz E.

Basic Res Cardiol. 2019 Jan 14;114(2):8. doi: 10.1007/s00395-019-0717-2.

PMID:
30643968
9.

Mitral Valve Repair Versus Replacement in Elderly With Degenerative Disease: Analysis of the STS Adult Cardiac Surgery Database.

Hendrix RJ, Bello RA, Flahive JM, Kakouros N, Aurigemma GP, Keaney JF, Hoffman W, Vassileva CM.

Ann Thorac Surg. 2019 Mar;107(3):747-753. doi: 10.1016/j.athoracsur.2018.09.018. Epub 2018 Oct 26.

PMID:
30612990
10.

VITAL Signs for Dietary Supplementation to Prevent Cancer and Heart Disease.

Keaney JF Jr, Rosen CJ.

N Engl J Med. 2019 Jan 3;380(1):91-93. doi: 10.1056/NEJMe1814933. Epub 2018 Nov 10. No abstract available.

PMID:
30415594
11.

Neuropolypathology as a result of severe traumatic brain injury?

Doherty CP, O'Keeffe E, Keaney J, Lawlor B, Coen RF, Farrell M, Campbell M.

Clin Neuropathol. 2019 Jan/Feb;38(1):14-22. doi: 10.5414/NP301131.

PMID:
30336803
12.

A systems-level framework for drug discovery identifies Csf1R as an anti-epileptic drug target.

Srivastava PK, van Eyll J, Godard P, Mazzuferi M, Delahaye-Duriez A, Steenwinckel JV, Gressens P, Danis B, Vandenplas C, Foerch P, Leclercq K, Mairet-Coello G, Cardenas A, Vanclef F, Laaniste L, Niespodziany I, Keaney J, Gasser J, Gillet G, Shkura K, Chong SA, Behmoaras J, Kadiu I, Petretto E, Kaminski RM, Johnson MR.

Nat Commun. 2018 Sep 3;9(1):3561. doi: 10.1038/s41467-018-06008-4.

13.

α1AMPK deletion in myelomonocytic cells induces a pro-inflammatory phenotype and enhances angiotensin II-induced vascular dysfunction.

Jansen T, Kröller-Schön S, Schönfelder T, Foretz M, Viollet B, Daiber A, Oelze M, Brandt M, Steven S, Kvandová M, Kalinovic S, Lagrange J, Keaney JF Jr, Münzel T, Wenzel P, Schulz E.

Cardiovasc Res. 2018 Dec 1;114(14):1883-1893. doi: 10.1093/cvr/cvy172.

PMID:
29982418
14.

First experience with zero-fluoroscopic ablation for supraventricular tachycardias using a novel impedance and magnetic-field-based mapping system.

Walsh KA, Galvin J, Keaney J, Keelan E, Szeplaki G.

Clin Res Cardiol. 2018 Jul;107(7):578-585. doi: 10.1007/s00392-018-1220-8. Epub 2018 Feb 23.

15.

Evaluation of the Tp-Te Interval, QTc and P-Wave Dispersion in Patients With Coronary Artery Ectasia.

Conlon R, Tanner R, David S, Szeplaki G, Galvin J, Keaney J, Keelan E, Boles U.

Cardiol Res. 2017 Dec;8(6):280-285. doi: 10.14740/cr631w. Epub 2017 Dec 22.

16.

Automated ultra-high-density mapping of peri-sinus node premature atrial contractions.

Walsh KA, Galvin J, Keaney J, Keelan E, Szeplaki G.

Clin Res Cardiol. 2018 Apr;107(4):368-370. doi: 10.1007/s00392-017-1191-1. Epub 2017 Dec 8. No abstract available.

PMID:
29222593
17.

Hdac3 regulates lymphovenous and lymphatic valve formation.

Janardhan HP, Milstone ZJ, Shin M, Lawson ND, Keaney JF Jr, Trivedi CM.

J Clin Invest. 2017 Nov 1;127(11):4193-4206. doi: 10.1172/JCI92852. Epub 2017 Oct 16.

18.

Activation of Inflammatory and Pro-Thrombotic Pathways in Acute Stress Cardiomyopathy.

Fitzgibbons TP, Edwards YJK, Shaw P, Iskandar A, Ahmed M, Bote J, Shah T, Sinha S, Gerszten RE, Keaney JF Jr, Zile MR, Aurigemma GP.

Front Cardiovasc Med. 2017 Aug 3;4:49. doi: 10.3389/fcvm.2017.00049. eCollection 2017.

19.

Short-Term Exposure to Ambient Air Pollution and Biomarkers of Systemic Inflammation: The Framingham Heart Study.

Li W, Dorans KS, Wilker EH, Rice MB, Ljungman PL, Schwartz JD, Coull BA, Koutrakis P, Gold DR, Keaney JF Jr, Vasan RS, Benjamin EJ, Mittleman MA.

Arterioscler Thromb Vasc Biol. 2017 Sep;37(9):1793-1800. doi: 10.1161/ATVBAHA.117.309799. Epub 2017 Jul 27.

20.

Prospective Relation of Circulating Adipokines to Incident Metabolic Syndrome: The Framingham Heart Study.

Zachariah JP, Quiroz R, Nelson KP, Teng Z, Keaney JF Jr, Sullivan LM, Vasan RS.

J Am Heart Assoc. 2017 Jul 16;6(7). pii: e004974. doi: 10.1161/JAHA.116.004974.

21.

Association of Parental Obesity and Diabetes Mellitus With Circulating Adipokines in Nonobese Nondiabetic Offspring.

Zachariah JP, Quiroz R, Enserro D, Andersson C, Keaney JF Jr, Sullivan LM, Vasan RS.

J Am Heart Assoc. 2017 Jul 16;6(7). pii: e004973. doi: 10.1161/JAHA.116.004973.

22.

CHIP-ping Away at Atherosclerosis.

Keaney JF Jr.

N Engl J Med. 2017 Jul 13;377(2):184-185. doi: 10.1056/NEJMe1706173. Epub 2017 Jun 21. No abstract available.

PMID:
28636833
23.

Mitochondrial retrograde signaling connects respiratory capacity to thermogenic gene expression.

Nam M, Akie TE, Sanosaka M, Craige SM, Kant S, Keaney JF Jr, Cooper MP.

Sci Rep. 2017 May 17;7(1):2013. doi: 10.1038/s41598-017-01879-x.

24.

Isolation of the superior vena cava to block unidirectional exit conduction from the right-sided pulmonary veins during atrial fibrillation ablation.

Szeplaki G, Keaney J, Keelan E, Valentine J, Galvin J.

J Interv Card Electrophysiol. 2017 Aug;49(2):127-128. doi: 10.1007/s10840-017-0251-9. Epub 2017 Apr 8. No abstract available.

PMID:
28391548
25.

PGC-1α dictates endothelial function through regulation of eNOS expression.

Craige SM, Kröller-Schön S, Li C, Kant S, Cai S, Chen K, Contractor MM, Pei Y, Schulz E, Keaney JF Jr.

Sci Rep. 2016 Dec 2;6:38210. doi: 10.1038/srep38210.

26.

Common Statistical Pitfalls in Basic Science Research.

Sullivan LM, Weinberg J, Keaney JF Jr.

J Am Heart Assoc. 2016 Sep 29;5(10). pii: e004142. Review. No abstract available.

27.

Suppression of ischemia in arterial occlusive disease by JNK-promoted native collateral artery development.

Ramo K, Sugamura K, Craige S, Keaney JF, Davis RJ.

Elife. 2016 Aug 9;5. pii: e18414. doi: 10.7554/eLife.18414.

28.

Blood-Brain Barrier Dysfunction as a Hallmark Pathology in Chronic Traumatic Encephalopathy.

Doherty CP, O'Keefe E, Wallace E, Loftus T, Keaney J, Kealy J, Humphries MM, Molloy MG, Meaney JF, Farrell M, Campbell M.

J Neuropathol Exp Neurol. 2016 Jul;75(7):656-62. doi: 10.1093/jnen/nlw036. Epub 2016 May 31.

29.

Adipose Tissue Depots and Their Cross-Sectional Associations With Circulating Biomarkers of Metabolic Regulation.

Lee JJ, Britton KA, Pedley A, Massaro JM, Speliotes EK, Murabito JM, Hoffmann U, Ingram C, Keaney JF Jr, Vasan RS, Fox CS.

J Am Heart Assoc. 2016 May 4;5(5). pii: e002936. doi: 10.1161/JAHA.115.002936.

30.

Short-Term Exposure to Air Pollution and Biomarkers of Oxidative Stress: The Framingham Heart Study.

Li W, Wilker EH, Dorans KS, Rice MB, Schwartz J, Coull BA, Koutrakis P, Gold DR, Keaney JF Jr, Lin H, Vasan RS, Benjamin EJ, Mittleman MA.

J Am Heart Assoc. 2016 Apr 28;5(5). pii: e002742. doi: 10.1161/JAHA.115.002742.

31.

The molecular basis of the genesis of basal tone in internal anal sphincter.

Zhang CH, Wang P, Liu DH, Chen CP, Zhao W, Chen X, Chen C, He WQ, Qiao YN, Tao T, Sun J, Peng YJ, Lu P, Zheng K, Craige SM, Lifshitz LM, Keaney JF Jr, Fogarty KE, ZhuGe R, Zhu MS.

Nat Commun. 2016 Apr 22;7:11358. doi: 10.1038/ncomms11358.

32.

Postmenopausal Hormone Therapy and Atherosclerosis--Time Is of the Essence.

Keaney JF Jr, Solomon CG.

N Engl J Med. 2016 Mar 31;374(13):1279-80. doi: 10.1056/NEJMe1602846. No abstract available.

PMID:
27028919
33.

Endothelial AMPK activation induces mitochondrial biogenesis and stress adaptation via eNOS-dependent mTORC1 signaling.

Li C, Reif MM, Craige SM, Kant S, Keaney JF Jr.

Nitric Oxide. 2016 May 1;55-56:45-53. doi: 10.1016/j.niox.2016.03.003. Epub 2016 Mar 14.

34.

Cross-Sectional Associations of Computed Tomography (CT)-Derived Adipose Tissue Density and Adipokines: The Framingham Heart Study.

Lee JJ, Pedley A, Hoffmann U, Massaro JM, Keaney JF Jr, Vasan RS, Fox CS.

J Am Heart Assoc. 2016 Feb 29;5(3):e002545. doi: 10.1161/JAHA.115.002545.

35.

A Simple and Portable Algorithm for Identifying Atrial Fibrillation in the Electronic Medical Record.

Khurshid S, Keaney J, Ellinor PT, Lubitz SA.

Am J Cardiol. 2016 Jan 15;117(2):221-5. doi: 10.1016/j.amjcard.2015.10.031. Epub 2015 Nov 6.

36.

Autoregulated paracellular clearance of amyloid-β across the blood-brain barrier.

Keaney J, Walsh DM, O'Malley T, Hudson N, Crosbie DE, Loftus T, Sheehan F, McDaid J, Humphries MM, Callanan JJ, Brett FM, Farrell MA, Humphries P, Campbell M.

Sci Adv. 2015 Sep 4;1(8):e1500472.

37.

Insights into Autism Spectrum Disorder Genomic Architecture and Biology from 71 Risk Loci.

Sanders SJ, He X, Willsey AJ, Ercan-Sencicek AG, Samocha KE, Cicek AE, Murtha MT, Bal VH, Bishop SL, Dong S, Goldberg AP, Jinlu C, Keaney JF 3rd, Klei L, Mandell JD, Moreno-De-Luca D, Poultney CS, Robinson EB, Smith L, Solli-Nowlan T, Su MY, Teran NA, Walker MF, Werling DM, Beaudet AL, Cantor RM, Fombonne E, Geschwind DH, Grice DE, Lord C, Lowe JK, Mane SM, Martin DM, Morrow EM, Talkowski ME, Sutcliffe JS, Walsh CA, Yu TW; Autism Sequencing Consortium, Ledbetter DH, Martin CL, Cook EH, Buxbaum JD, Daly MJ, Devlin B, Roeder K, State MW.

Neuron. 2015 Sep 23;87(6):1215-1233. doi: 10.1016/j.neuron.2015.09.016.

38.

The dynamic blood-brain barrier.

Keaney J, Campbell M.

FEBS J. 2015 Nov;282(21):4067-79. doi: 10.1111/febs.13412. Epub 2015 Sep 8. Review.

39.

Creating and Maintaining a Successful Service Line in an Academic Medical Center at the Dawn of Value-Based Care: Lessons Learned From the Heart and Vascular Service Line at UMass Memorial Health Care.

Phillips RA, Cyr J, Keaney JF Jr, Messina LM, Meyer TE, Tam SK, Korenda K, Darrigo M, Kumar P, Challapalli S.

Acad Med. 2015 Oct;90(10):1340-6. doi: 10.1097/ACM.0000000000000839.

PMID:
26222322
40.

Endothelial NADPH oxidase 4 protects ApoE-/- mice from atherosclerotic lesions.

Craige SM, Kant S, Reif M, Chen K, Pei Y, Angoff R, Sugamura K, Fitzgibbons T, Keaney JF Jr.

Free Radic Biol Med. 2015 Dec;89:1-7. doi: 10.1016/j.freeradbiomed.2015.07.004. Epub 2015 Jul 10.

41.

Pathophysiological role of oxidative stress in systolic and diastolic heart failure and its therapeutic implications.

Münzel T, Gori T, Keaney JF Jr, Maack C, Daiber A.

Eur Heart J. 2015 Oct 7;36(38):2555-64. doi: 10.1093/eurheartj/ehv305. Epub 2015 Jul 4. Review.

PMID:
26142467
42.

Proof That Lower Is Better--LDL Cholesterol and IMPROVE-IT.

Jarcho JA, Keaney JF Jr.

N Engl J Med. 2015 Jun 18;372(25):2448-50. doi: 10.1056/NEJMe1507041. Epub 2015 Jun 3. No abstract available.

PMID:
26039520
43.

Reactive oxygen species in endothelial function - from disease to adaptation - .

Craige SM, Kant S, Keaney JF Jr.

Circ J. 2015;79(6):1145-55. doi: 10.1253/circj.CJ-15-0464. Epub 2015 May 18. Review.

44.

Urban and rural differences in out-of-hospital cardiac arrest in Ireland.

Masterson S, Wright P, O'Donnell C, Vellinga A, Murphy AW, Hennelly D, Sinnott B, Egan J, O'Reilly M, Keaney J, Bury G, Deasy C.

Resuscitation. 2015 Jun;91:42-7. doi: 10.1016/j.resuscitation.2015.03.012. Epub 2015 Mar 26.

PMID:
25818707
45.

Balancing the risks and benefits of dual platelet inhibition.

Keaney JF Jr.

N Engl J Med. 2015 May 7;372(19):1854-6. doi: 10.1056/NEJMe1502137. Epub 2015 Mar 14. No abstract available.

PMID:
25773507
46.

Joseph A. Vita, MD, 1956-2014.

Keaney JF, Loscalzo J.

J Am Heart Assoc. 2015 Jan 26;4(1):e001778. doi: 10.1161/JAHA.115.001778. No abstract available.

47.

Joseph A. Vita, MD, 1956-2014.

Keaney JF Jr, Loscalzo J.

Circulation. 2015 Jan 27;131(4):432-3. doi: 10.1161/CIRCULATIONAHA.114.014964. No abstract available.

48.

No evidence for association of autism with rare heterozygous point mutations in Contactin-Associated Protein-Like 2 (CNTNAP2), or in Other Contactin-Associated Proteins or Contactins.

Murdoch JD, Gupta AR, Sanders SJ, Walker MF, Keaney J, Fernandez TV, Murtha MT, Anyanwu S, Ober GT, Raubeson MJ, DiLullo NM, Villa N, Waqar Z, Sullivan C, Gonzalez L, Willsey AJ, Choe SY, Neale BM, Daly MJ, State MW.

PLoS Genet. 2015 Jan 26;11(1):e1004852. doi: 10.1371/journal.pgen.1004852. eCollection 2015 Jan.

49.

Increased perforation risk with an MRI-conditional pacing lead: a single-center study.

Acha MR, Keaney JJ, Lubitz SA, Milan DJ, Mansour M, Heist KE, Ptaszek LM, Singh JP, Blendea D, Mela T.

Pacing Clin Electrophysiol. 2015 Mar;38(3):334-42. doi: 10.1111/pace.12550. Epub 2014 Dec 2.

PMID:
25469809
50.

De novo insertions and deletions of predominantly paternal origin are associated with autism spectrum disorder.

Dong S, Walker MF, Carriero NJ, DiCola M, Willsey AJ, Ye AY, Waqar Z, Gonzalez LE, Overton JD, Frahm S, Keaney JF 3rd, Teran NA, Dea J, Mandell JD, Hus Bal V, Sullivan CA, DiLullo NM, Khalil RO, Gockley J, Yuksel Z, Sertel SM, Ercan-Sencicek AG, Gupta AR, Mane SM, Sheldon M, Brooks AI, Roeder K, Devlin B, State MW, Wei L, Sanders SJ.

Cell Rep. 2014 Oct 9;9(1):16-23. doi: 10.1016/j.celrep.2014.08.068. Epub 2014 Oct 2.

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