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Ultrafast Brain Magnetic Resonance Imaging in Acute Neurological Emergencies: Diagnostic Accuracy and Impact on Patient Management.

Kazmierczak PM, Dührsen M, Forbrig R, Patzig M, Klein M, Pomschar A, Kunz WG, Puhr-Westerheide D, Ricke J, Solyanik O, Cyran CC.

Invest Radiol. 2020 Jan 8. doi: 10.1097/RLI.0000000000000625. [Epub ahead of print]


The added diagnostic value of complementary gadoxetic acid-enhanced MRI to 18F-DOPA-PET/CT for liver staging in medullary thyroid carcinoma.

Puhr-Westerheide D, Cyran CC, Sargsyan-Bergmann J, Todica A, Gildehaus FJ, Kunz WG, Stahl R, Spitzweg C, Ricke J, Kazmierczak PM.

Cancer Imaging. 2019 Nov 14;19(1):73. doi: 10.1186/s40644-019-0263-z.


Incremental Value of Computed Tomography Perfusion for Final Infarct Prediction in Acute Ischemic Cerebellar Stroke.

Fabritius MP, Reidler P, Froelich MF, Rotkopf LT, Liebig T, Kellert L, Feil K, Tiedt S, Kazmierczak PM, Thierfelder KM, Puhr-Westerheide D, Kunz WG.

J Am Heart Assoc. 2019 Nov 5;8(21):e013069. doi: 10.1161/JAHA.119.013069. Epub 2019 Oct 19.


Clinical and Imaging Parameters Associated With Hyperacute Infarction Growth in Large Vessel Occlusion Stroke.

Puhr-Westerheide D, Tiedt S, Rotkopf LT, Herzberg M, Reidler P, Fabritius MP, Kazmierczak PM, Kellert L, Feil K, Thierfelder KM, Dorn F, Liebig T, Wollenweber FA, Kunz WG.

Stroke. 2019 Oct;50(10):2799-2804. doi: 10.1161/STROKEAHA.119.025809. Epub 2019 Aug 20.


Neuronal injury biomarkers for assessment of the individual cognitive reserve in clinically suspected Alzheimer's disease.

Beyer L, Schnabel J, Kazmierczak P, Ewers M, Schönecker S, Prix C, Meyer-Wilmes J, Unterrainer M, Catak C, Pogarell O, Perneczky R, Albert NL, Bartenstein P, Danek A, Buerger K, Levin J, Rominger A, Brendel M.

Neuroimage Clin. 2019;24:101949. doi: 10.1016/j.nicl.2019.101949. Epub 2019 Jul 22.


[Prevention of "contrast-induced" acute kidney injury - practical considerations].

Weidenbusch M, Wörnle M, Kazmierczak P, Ricke J, Fischereder M.

Dtsch Med Wochenschr. 2019 Aug;144(15):1009-1013. doi: 10.1055/a-0840-7315. Epub 2019 Jul 26. German.


Correction: Development of highly active anti-Pneumocystis bisbenzamidines: insight into the influence of selected substituents on the in vitro activity.

Maciejewska D, Żabiński J, Rezler M, Kaźmierczak P, Collins MS, Ficker L, Cushion MT.

Medchemcomm. 2017 Nov 7;8(11):2164. doi: 10.1039/c7md90042b. eCollection 2017 Nov 1.


Integrin-targeted quantitative optoacoustic imaging with MRI correlation for monitoring a BRAF/MEK inhibitor combination therapy in a murine model of human melanoma.

Kazmierczak PM, Burton NC, Keinrath G, Hirner-Eppeneder H, Schneider MJ, Eschbach RS, Heimer M, Solyanik O, Todica A, Reiser MF, Ricke J, Cyran CC.

PLoS One. 2018 Oct 3;13(10):e0204930. doi: 10.1371/journal.pone.0204930. eCollection 2018.


Identification and characterization of myocardial metastases in neuroendocrine tumor patients using 68Ga-DOTATATE PET-CT.

Kunz WG, Eschbach RS, Stahl R, Kazmierczak PM, Bartenstein P, Rominger A, Auernhammer CJ, Spitzweg C, Ricke J, Cyran CC.

Cancer Imaging. 2018 Sep 20;18(1):34. doi: 10.1186/s40644-018-0168-2.


Development of highly active anti-Pneumocystis bisbenzamidines: insight into the influence of selected substituents on the in vitro activity.

Maciejewska D, Żabiński J, Rezler M, Kaźmierczak P, Collins MS, Ficker L, Cushion MT.

Medchemcomm. 2017 Oct 5;8(10):2003-2011. doi: 10.1039/c7md00445a. eCollection 2017 Oct 1. Erratum in: Medchemcomm. 2017 Nov 7;8(11):2164.


CT attenuation of liver metastases before targeted therapy is a prognostic factor of overall survival in colorectal cancer patients. Results from the randomised, open-label FIRE-3/AIO KRK0306 trial.

Froelich MF, Heinemann V, Sommer WH, Holch JW, Schoeppe F, Hesse N, Baumann AB, Kunz WG, Reiser MF, Ricke J, D'Anastasi M, Stintzing S, Modest DP, Kazmierczak PM, Hofmann FO.

Eur Radiol. 2018 Dec;28(12):5284-5292. doi: 10.1007/s00330-018-5454-7. Epub 2018 Jun 7.


TRPV6, TRPM6 and TRPM7 Do Not Contribute to Hair-Cell Mechanotransduction.

Morgan CP, Zhao H, LeMasurier M, Xiong W, Pan B, Kazmierczak P, Avenarius MR, Bateschell M, Larisch R, Ricci AJ, Müller U, Barr-Gillespie PG.

Front Cell Neurosci. 2018 Feb 20;12:41. doi: 10.3389/fncel.2018.00041. eCollection 2018.


18F-FDG-PET/CT and diffusion-weighted MRI for monitoring a BRAF and CDK 4/6 inhibitor combination therapy in a murine model of human melanoma.

Eschbach RS, Kazmierczak PM, Heimer MM, Todica A, Hirner-Eppeneder H, Schneider MJ, Keinrath G, Solyanik O, Olivier J, Kunz WG, Reiser MF, Bartenstein P, Ricke J, Cyran CC.

Cancer Imaging. 2018 Jan 18;18(1):2. doi: 10.1186/s40644-018-0135-y.


Improved Detection of Transosseous Meningiomas Using 68Ga-DOTATATE PET/CT Compared with Contrast-Enhanced MRI.

Kunz WG, Jungblut LM, Kazmierczak PM, Vettermann FJ, Bollenbacher A, Tonn JC, Schichor C, Rominger A, Albert NL, Bartenstein P, Reiser MF, Cyran CC.

J Nucl Med. 2017 Oct;58(10):1580-1587. doi: 10.2967/jnumed.117.191932. Epub 2017 Apr 27.


Reversal of CT Hypodensity in Chronic Ischemic Stroke : A Different Kind of Fogging.

Fabritius MP, Kazmierczak PM, Thierfelder KM, Kunz WG.

Clin Neuroradiol. 2017 Sep;27(3):383-384. doi: 10.1007/s00062-017-0570-3. Epub 2017 Mar 2. No abstract available.


Pejvakin, a Candidate Stereociliary Rootlet Protein, Regulates Hair Cell Function in a Cell-Autonomous Manner.

Kazmierczak M, Kazmierczak P, Peng AW, Harris SL, Shah P, Puel JL, Lenoir M, Franco SJ, Schwander M.

J Neurosci. 2017 Mar 29;37(13):3447-3464. doi: 10.1523/JNEUROSCI.2711-16.2017. Epub 2017 Feb 16.


Contrast-Enhanced Ultrasound with VEGFR2-Targeted Microbubbles for Monitoring Regorafenib Therapy Effects in Experimental Colorectal Adenocarcinomas in Rats with DCE-MRI and Immunohistochemical Validation.

Eschbach RS, Clevert DA, Hirner-Eppeneder H, Ingrisch M, Moser M, Schuster J, Tadros D, Schneider M, Kazmierczak PM, Reiser M, Cyran CC.

PLoS One. 2017 Jan 6;12(1):e0169323. doi: 10.1371/journal.pone.0169323. eCollection 2017.


68Ga-TRAP-(RGD)3 Hybrid Imaging for the In Vivo Monitoring of αvß3-Integrin Expression as Biomarker of Anti-Angiogenic Therapy Effects in Experimental Breast Cancer.

Kazmierczak PM, Todica A, Gildehaus FJ, Hirner-Eppeneder H, Brendel M, Eschbach RS, Hellmann M, Nikolaou K, Reiser MF, Wester HJ, Kropf S, Rominger A, Cyran CC.

PLoS One. 2016 Dec 19;11(12):e0168248. doi: 10.1371/journal.pone.0168248. eCollection 2016.


Diagnostic accuracy of contemporary multidetector computed tomography (MDCT) for the detection of lumbar disc herniation.

Notohamiprodjo S, Stahl R, Braunagel M, Kazmierczak PM, Thierfelder KM, Treitl KM, Wirth S, Notohamiprodjo M.

Eur Radiol. 2017 Aug;27(8):3443-3451. doi: 10.1007/s00330-016-4686-7. Epub 2016 Dec 17.


αvß3-Integrin-Targeted Magnetic Resonance Imaging for the Assessment of Early Antiangiogenic Therapy Effects in Orthotopic Breast Cancer Xenografts.

Kazmierczak PM, Schneider M, Habereder T, Hirner-Eppeneder H, Eschbach RS, Moser M, Reiser MF, Lauber K, Nikolaou K, Cyran CC.

Invest Radiol. 2016 Nov;51(11):746-755.


The added value of 68Ga-DOTA-TATE-PET to contrast-enhanced CT for primary site detection in CUP of neuroendocrine origin.

Kazmierczak PM, Rominger A, Wenter V, Spitzweg C, Auernhammer C, Angele MK, Rist C, Cyran CC.

Eur Radiol. 2017 Apr;27(4):1676-1684. doi: 10.1007/s00330-016-4475-3. Epub 2016 Jul 19.


Evaluation of selected dietary behaviours of students according to gender and nutritional knowledge.

Zaborowicz K, Czarnocińska J, Galiński G, Kaźmierczak P, Górska K, Durczewski P.

Rocz Panstw Zakl Hig. 2016;67(1):45-50.


Determinants of quality of life in patients with breast cancer undergoing external beam radiotherapy.

Chalubinska-Fendler J, Butwicka A, Kaźmierczak P, Jałocha-Kaczka A, Fendler W, Fijuth J.

Arch Med Sci. 2015 Dec 10;11(6):1361-2. doi: 10.5114/aoms.2015.56367. Epub 2015 Dec 11. No abstract available.


Progressive Hearing Loss in Mice Carrying a Mutation in Usp53.

Kazmierczak M, Harris SL, Kazmierczak P, Shah P, Starovoytov V, Ohlemiller KK, Schwander M.

J Neurosci. 2015 Nov 25;35(47):15582-98. doi: 10.1523/JNEUROSCI.1965-15.2015.


Severe Congenital Obstruction of the Left Main Coronary Artery Coexisting With Supravalvular Aortic Stenosis in Williams Syndrome: A Dangerous Association.

Szaflik K, Kaźmierczak P, Moll JJ, Moll JA.

World J Pediatr Congenit Heart Surg. 2016 Mar;7(2):216-9. doi: 10.1177/2150135115586269. Epub 2015 Nov 18.


Monitoring Cell Death in Regorafenib-Treated Experimental Colon Carcinomas Using Annexin-Based Optical Fluorescence Imaging Validated by Perfusion MRI.

Kazmierczak PM, Burian E, Eschbach R, Hirner-Eppeneder H, Moser M, Havla L, Eisenblätter M, Reiser MF, Nikolaou K, Cyran CC.

PLoS One. 2015 Sep 22;10(9):e0138452. doi: 10.1371/journal.pone.0138452. eCollection 2015.


Pentamidine analogs as inhibitors of [(3)H]MK-801 and [(3)H]ifenprodil binding to rat brain NMDA receptors.

Berger ML, Maciejewska D, Vanden Eynde JJ, Mottamal M, Żabiński J, Kaźmierczak P, Rezler M, Jarak I, Piantanida I, Karminski-Zamola G, Mayence A, Rebernik P, Kumar A, Ismail MA, Boykin DW, Huang TL.

Bioorg Med Chem. 2015 Aug 1;23(15):4489-500. doi: 10.1016/j.bmc.2015.06.012. Epub 2015 Jun 14.


β-Resorcylidene aminoguanidine (RAG) dilates coronary arteries in an endothelium-independent manner.

Kazmierczak PA, Dobaczewski MP, Przygodzki T, Carsky J, Watala C.

Pharmacol Rep. 2015 Jun;67(3):631-5. doi: 10.1016/j.pharep.2015.01.003. Epub 2015 Jan 20.


Probing the relationship between anti-Pneumocystis carinii activity and DNA binding of bisamidines by molecular dynamics simulations.

Żołek T, Maciejewska D, Żabiński J, Kaźmierczak P, Rezler M.

Molecules. 2015 Apr 3;20(4):5942-64. doi: 10.3390/molecules20045942.


Correlation of perfusion MRI and 18F-FDG PET imaging biomarkers for monitoring regorafenib therapy in experimental colon carcinomas with immunohistochemical validation.

Eschbach RS, Fendler WP, Kazmierczak PM, Hacker M, Rominger A, Carlsen J, Hirner-Eppeneder H, Schuster J, Moser M, Havla L, Schneider MJ, Ingrisch M, Spaeth L, Reiser MF, Nikolaou K, Cyran CC.

PLoS One. 2015 Feb 10;10(2):e0115543. doi: 10.1371/journal.pone.0115543. eCollection 2015.


Improved detection of hypervascular liver lesions with CAIPIRINHA-Dixon-TWIST-volume-interpolated breath-hold examination.

Kazmierczak PM, Theisen D, Thierfelder KM, Sommer WH, Reiser MF, Notohamiprodjo M, Nikolaou K.

Invest Radiol. 2015 Mar;50(3):153-60. doi: 10.1097/RLI.0000000000000118.


Dynamic contrast-enhanced magnetic resonance imaging assessment of kidney function and renal masses: single slice versus whole organ/tumor.

Winter KS, Helck AD, Ingrisch M, Staehler M, Stief C, Sommer WH, Braunagel M, Kazmierczak PM, Reiser MF, Nikolaou K, Notohamiprodjo M.

Invest Radiol. 2014 Nov;49(11):720-7. doi: 10.1097/RLI.0000000000000075.


In vitro screening of pentamidine analogs against bacterial and fungal strains.

Maciejewska D, Żabiński J, Kaźmierczak P, Wójciuk K, Kruszewski M, Kruszewska H.

Bioorg Med Chem Lett. 2014 Jul 1;24(13):2918-23. doi: 10.1016/j.bmcl.2014.04.075. Epub 2014 Apr 30.


Non-contrast-enhanced MR angiography at 3 Tesla in patients with advanced peripheral arterial occlusive disease.

Thierfelder KM, Meimarakis G, Nikolaou K, Sommer WH, Schmitt P, Kazmierczak PM, Reiser MF, Theisen D.

PLoS One. 2014 Mar 7;9(3):e91078. doi: 10.1371/journal.pone.0091078. eCollection 2014.


[Radiological diagnostics in CUP syndrome].

Kazmierczak PM, Nikolaou K, Rominger A, Graser A, Reiser MF, Cyran CC.

Radiologe. 2014 Feb;54(2):117-23. doi: 10.1007/s00117-013-2547-9. German.


Regorafenib effects on human colon carcinoma xenografts monitored by dynamic contrast-enhanced computed tomography with immunohistochemical validation.

Cyran CC, Kazmierczak PM, Hirner H, Moser M, Ingrisch M, Havla L, Michels A, Eschbach R, Schwarz B, Reiser MF, Bruns CJ, Nikolaou K.

PLoS One. 2013 Sep 30;8(9):e76009. doi: 10.1371/journal.pone.0076009. eCollection 2013.


Cor triatriatum sinister in a newborn with transposition of the great arteries.

Kazmierczak PA, Moll JA, Moll JJ.

World J Pediatr Congenit Heart Surg. 2012 Oct 1;3(4):534-5. doi: 10.1177/2150135112450590. No abstract available.


Repair of anomalous origin of the left coronary artery from the pulmonary artery in infants.

Kazmierczak PA, Ostrowska K, Dryzek P, Moll JA, Moll JJ.

Interact Cardiovasc Thorac Surg. 2013 Jun;16(6):797-801. doi: 10.1093/icvts/ivt061. Epub 2013 Feb 26.


TMHS is an integral component of the mechanotransduction machinery of cochlear hair cells.

Xiong W, Grillet N, Elledge HM, Wagner TF, Zhao B, Johnson KR, Kazmierczak P, Müller U.

Cell. 2012 Dec 7;151(6):1283-95. doi: 10.1016/j.cell.2012.10.041.


[The Hamatometacarpale-IV fracture-dislocation: a rare injury of amateur boxers].

Kazmierczak PM, Strobl FF, Notohamiprodjo M.

Rofo. 2013 Feb;185(2):175-6. doi: 10.1055/s-0032-1325516. Epub 2012 Nov 5. German. No abstract available.


The mycovirus CHV1 disrupts secretion of a developmentally regulated protein in Cryphonectria parasitica.

Kazmierczak P, McCabe P, Turina M, Jacob-Wilk D, Van Alfen NK.

J Virol. 2012 Jun;86(11):6067-74. doi: 10.1128/JVI.05756-11. Epub 2012 Mar 21.


Differential expression of the putative Kex2 processed and secreted aspartic proteinase gene family of Cryphonectria parasitica.

Jacob-Wilk D, Moretti M, Turina M, Kazmierczak P, Van Alfen NK.

Fungal Biol. 2012 Mar;116(3):363-78. doi: 10.1016/j.funbio.2011.12.006. Epub 2012 Jan 6.


N-Methyl-2-pyridone-5-carboxamide is 1-methylnicotinamide metabolite of low cyclooxygenase-dependent vasodilating activity.

Przygodzki T, Grobelski B, Kazmierczak P, Watala C.

J Physiol Biochem. 2012 Sep;68(3):329-34. doi: 10.1007/s13105-012-0144-4. Epub 2012 Jan 13. Erratum in: J Physiol Biochem. 2012 Jun;68(2):305.


Analogs of pentamidine as potential anti-Pneumocystis chemotherapeutics.

Maciejewska D, Zabinski J, Kaźmierczak P, Rezler M, Krassowska-Świebocka B, Collins MS, Cushion MT.

Eur J Med Chem. 2012 Feb;48:164-73. doi: 10.1016/j.ejmech.2011.12.010. Epub 2011 Dec 13.


Sensing sound: molecules that orchestrate mechanotransduction by hair cells.

Kazmierczak P, Müller U.

Trends Neurosci. 2012 Apr;35(4):220-9. doi: 10.1016/j.tins.2011.10.007. Epub 2011 Dec 15. Review.


Development and regeneration of sensory transduction in auditory hair cells requires functional interaction between cadherin-23 and protocadherin-15.

Lelli A, Kazmierczak P, Kawashima Y, Müller U, Holt JR.

J Neurosci. 2010 Aug 25;30(34):11259-69. doi: 10.1523/JNEUROSCI.1949-10.2010.


1-methylnicotinamide effects on the selected markers of endothelial function, inflammation and haemostasis in diabetic rats.

Przygodzki T, Kazmierczak P, Sikora J, Watala C.

Eur J Pharmacol. 2010 Aug 25;640(1-3):157-62. doi: 10.1016/j.ejphar.2010.05.014. Epub 2010 May 25.


Structure of the N terminus of cadherin 23 reveals a new adhesion mechanism for a subset of cadherin superfamily members.

Elledge HM, Kazmierczak P, Clark P, Joseph JS, Kolatkar A, Kuhn P, Müller U.

Proc Natl Acad Sci U S A. 2010 Jun 8;107(23):10708-12. doi: 10.1073/pnas.1006284107. Epub 2010 May 24.


The mechanotransduction machinery of hair cells.

Grillet N, Kazmierczak P, Xiong W, Schwander M, Reynolds A, Sakaguchi H, Tokita J, Kachar B, Müller U.

Sci Signal. 2009 Aug 25;2(85):pt5. doi: 10.1126/scisignal.285pt5.


Resorcylidene aminoguanidine induces antithrombotic action that is not dependent on its antiglycation activity.

Watala C, Dobaczewski M, Kazmierczak P, Gebicki J, Nocun M, Zitnanova I, Ulicna O, Durackova Z, Waczulíková I, Carsky J, Chlopicki S.

Vascul Pharmacol. 2009 Oct;51(4):275-83. doi: 10.1016/j.vph.2009.07.002. Epub 2009 Jul 24.


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