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Items: 1 to 50 of 199

1.

Oncosuppressive Role of RUNX3 in Human Astrocytomas.

Steponaitis G, Kazlauskas A, Vaitkienė P, Deltuva VP, Mikuciunas M, Skiriutė D.

J Oncol. 2019 Aug 5;2019:1232434. doi: 10.1155/2019/1232434. eCollection 2019.

2.

Significance of Amphiregulin (AREG) for the Outcome of Low and High Grade Astrocytoma Patients.

Steponaitis G, Kazlauskas A, Skiriute D, Vaitkiene P, Skauminas K, Tamasauskas A.

J Cancer. 2019 Feb 23;10(6):1479-1488. doi: 10.7150/jca.29282. eCollection 2019.

3.

Isocytosine deaminase Vcz as a novel tool for the prodrug cancer therapy.

Kazlauskas A, Darinskas A, Meškys R, Tamašauskas A, Urbonavičius J.

BMC Cancer. 2019 Mar 4;19(1):197. doi: 10.1186/s12885-019-5409-7.

4.

Importance of the putative furin recognition site 742RNRR745 for antiangiogenic Sema3C activity in vitro.

Valiulyte I, Preitakaite V, Tamasauskas A, Kazlauskas A.

Braz J Med Biol Res. 2018 Oct 8;51(11):e7786. doi: 10.1590/1414-431X20187786.

5.

Potential lymphangiogenesis therapies: Learning from current antiangiogenesis therapies-A review.

Yamakawa M, Doh SJ, Santosa SM, Montana M, Qin EC, Kong H, Han KY, Yu C, Rosenblatt MI, Kazlauskas A, Chang JH, Azar DT.

Med Res Rev. 2018 Sep;38(6):1769-1798. doi: 10.1002/med.21496. Epub 2018 Mar 12. Review.

6.

Microenvironment dependent gene expression signatures in reprogrammed human colon normal and cancer cell lines.

Strainiene E, Binkis M, Urnikyte S, Stankevicius V, Sasnauskiene A, Kundrotas G, Kazlauskas A, Suziedelis K.

BMC Cancer. 2018 Feb 27;18(1):222. doi: 10.1186/s12885-018-4145-8.

7.

ER stress-induced aggresome trafficking of HtrA1 protects against proteotoxicity.

Gerhardt MJ, Marsh JA, Morrison M, Kazlauskas A, Khadka A, Rosenkranz S, DeAngelis MM, Saint-Geniez M, Jacobo SMP.

J Mol Cell Biol. 2017 Dec 1;9(6):533. doi: 10.1093/jmcb/mjx040. No abstract available.

PMID:
29040612
8.

ER stress-induced aggresome trafficking of HtrA1 protects against proteotoxicity.

Gerhardt MJ, Marsh JA, Morrison M, Kazlauskas A, Khadka A, Rosenkranz S, DeAngelis MM, Saint-Geniez M, Jacobo SMP.

J Mol Cell Biol. 2017 Dec 1;9(6):516-532. doi: 10.1093/jmcb/mjx024. Erratum in: J Mol Cell Biol. 2017 Dec 1;9(6):533.

9.

The Effect of Sodium Valproate on the Glioblastoma U87 Cell Line Tumor Development on the Chicken Embryo Chorioallantoic Membrane and on EZH2 and p53 Expression.

Kavaliauskaitė D, Stakišaitis D, Martinkutė J, Šlekienė L, Kazlauskas A, Balnytė I, Lesauskaitė V, Valančiūtė A.

Biomed Res Int. 2017;2017:6326053. doi: 10.1155/2017/6326053. Epub 2017 May 31.

10.

Development of wound healing models to study TGFβ3's effect on SMA.

Sriram S, Tran JA, Guo X, Hutcheon AEK, Kazlauskas A, Zieske JD.

Exp Eye Res. 2017 Aug;161:52-60. doi: 10.1016/j.exer.2017.06.005. Epub 2017 Jun 6.

11.

PDGFs and their receptors.

Kazlauskas A.

Gene. 2017 May 30;614:1-7. doi: 10.1016/j.gene.2017.03.003. Epub 2017 Mar 4. Review.

12.

PDGFRα Is a Key Regulator of T1 and T3's Differential Effect on SMA Expression in Human Corneal Fibroblasts.

Sriram S, Tran JA, Guo X, Hutcheon AE, Lei H, Kazlauskas A, Zieske JD.

Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):1179-1186. doi: 10.1167/iovs.16-20016.

13.

Testin (TES) as a candidate tumour suppressor and prognostic marker in human astrocytoma.

Steponaitis G, Kazlauskas A, Skiriute D, Valiulyte I, Skauminas K, Tamasauskas A, Vaitkiene P.

Oncol Lett. 2016 Nov;12(5):3305-3311. Epub 2016 Sep 1.

14.

Prevention of Proliferative Vitreoretinopathy by Suppression of Phosphatidylinositol 5-Phosphate 4-Kinases.

Ma G, Duan Y, Huang X, Qian CX, Chee Y, Mukai S, Cui J, Samad A, Matsubara JA, Kazlauskas A, D'Amore PA, Gu S, Lei H.

Invest Ophthalmol Vis Sci. 2016 Jul 1;57(8):3935-43. doi: 10.1167/iovs.16-19405. Erratum in: Invest Ophthalmol Vis Sci. 2016 Aug 1;57(10):4213.

15.

Large-Scale Screening of Preferred Interactions of Human Src Homology-3 (SH3) Domains Using Native Target Proteins as Affinity Ligands.

Kazlauskas A, Schmotz C, Kesti T, Hepojoki J, Kleino I, Kaneko T, Li SS, Saksela K.

Mol Cell Proteomics. 2016 Oct;15(10):3270-3281. Epub 2016 Jul 20.

16.

Vascular Endothelial Cell Growth Factor A Acts via Platelet-Derived Growth Factor Receptor α To Promote Viability of Cells Enduring Hypoxia.

Pennock S, Kim LA, Kazlauskas A.

Mol Cell Biol. 2016 Aug 26;36(18):2314-27. doi: 10.1128/MCB.01019-15. Print 2016 Sep 15.

17.

High CHI3L1 expression is associated with glioma patient survival.

Steponaitis G, Skiriutė D, Kazlauskas A, Golubickaitė I, Stakaitis R, Tamašauskas A, Vaitkienė P.

Diagn Pathol. 2016 Apr 27;11:42. doi: 10.1186/s13000-016-0492-4.

18.

High level of Sema3C is associated with glioma malignancy.

Vaitkienė P, Skiriutė D, Steponaitis G, Skauminas K, Tamašauskas A, Kazlauskas A.

Diagn Pathol. 2015 Jun 2;10:58. doi: 10.1186/s13000-015-0298-9.

19.

Hepatitis C virus NS5A protein blocks epidermal growth factor receptor degradation via a proline motif- dependent interaction.

Igloi Z, Kazlauskas A, Saksela K, Macdonald A, Mankouri J, Harris M.

J Gen Virol. 2015 Aug;96(8):2133-44. doi: 10.1099/vir.0.000145. Epub 2015 Apr 13.

20.

Epitope Specificity Determines Pathogenicity and Detectability of Anti-Platelet-Derived Growth Factor Receptor α Autoantibodies in Systemic Sclerosis.

Moroncini G, Grieco A, Nacci G, Paolini C, Tonnini C, Pozniak KN, Cuccioloni M, Mozzicafreddo M, Svegliati S, Angeletti M, Kazlauskas A, Avvedimento EV, Funaro A, Gabrielli A.

Arthritis Rheumatol. 2015 Jul;67(7):1891-903. doi: 10.1002/art.39125.

21.

RasGAP Promotes Autophagy and Thereby Suppresses Platelet-Derived Growth Factor Receptor-Mediated Signaling Events, Cellular Responses, and Pathology.

Lei H, Qian CX, Lei J, Haddock LJ, Mukai S, Kazlauskas A.

Mol Cell Biol. 2015 May;35(10):1673-85. doi: 10.1128/MCB.01248-14. Epub 2015 Mar 2.

22.

Insulin-like growth factor 1 (IGF-1) stabilizes nascent blood vessels.

Jacobo SM, Kazlauskas A.

J Biol Chem. 2015 Mar 6;290(10):6349-60. doi: 10.1074/jbc.M114.634154. Epub 2015 Jan 6.

23.

Lysophosphatidic acid contributes to angiogenic homeostasis.

Kazlauskas A.

Exp Cell Res. 2015 May 1;333(2):166-70. doi: 10.1016/j.yexcr.2014.11.012. Epub 2014 Nov 26. Review. No abstract available.

PMID:
25433269
24.

Vascular endothelial growth factor acts primarily via platelet-derived growth factor receptor α to promote proliferative vitreoretinopathy.

Pennock S, Haddock LJ, Mukai S, Kazlauskas A.

Am J Pathol. 2014 Nov;184(11):3052-68. doi: 10.1016/j.ajpath.2014.07.026. Epub 2014 Sep 26.

25.

Plakophilin-2 promotes activation of epidermal growth factor receptor.

Kazlauskas A.

Mol Cell Biol. 2014 Oct;34(20):3778-9. doi: 10.1128/MCB.00968-14. Epub 2014 Aug 11.

26.

Glioma Malignancy-Dependent NDRG2 Gene Methylation and Downregulation Correlates with Poor Patient Outcome.

Skiriutė D, Steponaitis G, Vaitkienė P, Mikučiūnas M, Skauminas K, Tamašauskas A, Kazlauskas A.

J Cancer. 2014 May 13;5(6):446-56. doi: 10.7150/jca.9140. eCollection 2014.

27.

Pericytes prevent regression of endothelial cell tubes by accelerating metabolism of lysophosphatidic acid.

Motiejūnaitė R, Aranda J, Kazlauskas A.

Microvasc Res. 2014 May;93:62-71. doi: 10.1016/j.mvr.2014.03.003. Epub 2014 Mar 27.

PMID:
24681425
28.

Is neutralizing vitreal growth factors a viable strategy to prevent proliferative vitreoretinopathy?

Pennock S, Haddock LJ, Eliott D, Mukai S, Kazlauskas A.

Prog Retin Eye Res. 2014 May;40:16-34. doi: 10.1016/j.preteyeres.2013.12.006. Epub 2014 Jan 9. Review.

PMID:
24412519
29.

A reactive oxygen species-mediated, self-perpetuating loop persistently activates platelet-derived growth factor receptor α.

Lei H, Kazlauskas A.

Mol Cell Biol. 2014 Jan;34(1):110-22. doi: 10.1128/MCB.00839-13. Epub 2013 Nov 4.

30.

Hepatitis C virus NS5A inhibits mixed lineage kinase 3 to block apoptosis.

Amako Y, Igloi Z, Mankouri J, Kazlauskas A, Saksela K, Dallas M, Peers C, Harris M.

J Biol Chem. 2013 Aug 23;288(34):24753-63. doi: 10.1074/jbc.M113.491985. Epub 2013 Jul 15.

31.

Detection of H2O2-mediated phosphorylation of kinase-inactive PDGFRα.

Lei H, Kazlauskas A.

Methods Enzymol. 2013;528:189-94. doi: 10.1016/B978-0-12-405881-1.00011-2.

PMID:
23849866
32.
33.

Ranibizumab is a potential prophylaxis for proliferative vitreoretinopathy, a nonangiogenic blinding disease.

Pennock S, Kim D, Mukai S, Kuhnle M, Chun DW, Matsubara J, Cui J, Ma P, Maberley D, Samad A, Van Geest RJ, Oberstein SL, Schlingemann RO, Kazlauskas A.

Am J Pathol. 2013 May;182(5):1659-70. doi: 10.1016/j.ajpath.2013.01.052. Epub 2013 Apr 9.

34.

Regression activity that is naturally present in vitreous becomes ineffective as patients develop proliferative diabetic retinopathy.

Aranda J, Motiejunaite R, Silva P, Aiello LP, Kazlauskas A.

Diabetologia. 2013 Jun;56(6):1444-53. doi: 10.1007/s00125-013-2884-2. Epub 2013 Mar 19.

35.

Age-related macular degeneration-associated silent polymorphisms in HtrA1 impair its ability to antagonize insulin-like growth factor 1.

Jacobo SM, Deangelis MM, Kim IK, Kazlauskas A.

Mol Cell Biol. 2013 May;33(10):1976-90. doi: 10.1128/MCB.01283-12. Epub 2013 Mar 11.

36.

SU9518 inhibits proliferative vitreoretinopathy in fibroblast and genetically modified Müller cell-induced rabbit models.

Velez G, Weingarden AR, Lei H, Kazlauskas A, Gao G.

Invest Ophthalmol Vis Sci. 2013 Feb 19;54(2):1392-7. doi: 10.1167/iovs.12-10320.

37.

PDGF receptor-α does not promote HCMV entry into epithelial and endothelial cells but increased quantities stimulate entry by an abnormal pathway.

Vanarsdall AL, Wisner TW, Lei H, Kazlauskas A, Johnson DC.

PLoS Pathog. 2012 Sep;8(9):e1002905. doi: 10.1371/journal.ppat.1002905. Epub 2012 Sep 13.

38.

Retinal Pigment Epithelium and Müller Progenitor Cell Interaction Increase Müller Progenitor Cell Expression of PDGFRα and Ability to Induce Proliferative Vitreoretinopathy in a Rabbit Model.

Velez G, Weingarden AR, Tucker BA, Lei H, Kazlauskas A, Young MJ.

Stem Cells Int. 2012;2012:106486. doi: 10.1155/2012/106486. Epub 2012 Aug 23.

39.

A novel function of p53: a gatekeeper of retinal detachment.

Lei H, Rheaume MA, Cui J, Mukai S, Maberley D, Samad A, Matsubara J, Kazlauskas A.

Am J Pathol. 2012 Sep;181(3):866-74. doi: 10.1016/j.ajpath.2012.05.036.

40.

A phage display-based approach to investigate abnormal neovessels of the retina.

Staniszewska M, Gu X, Romano C, Kazlauskas A.

Invest Ophthalmol Vis Sci. 2012 Jul 3;53(8):4371-9. doi: 10.1167/iovs.12-9690.

PMID:
22661481
41.

VEGF-A engages at least three tyrosine kinases to activate PI3K/Akt.

Ruan GX, Kazlauskas A.

Cell Cycle. 2012 Jun 1;11(11):2047-8. doi: 10.4161/cc.20535. Epub 2012 Jun 1. No abstract available.

42.

Primary human endothelial cells secrete agents that reduce responsiveness to lysophosphatidic acid (LPA).

Park EY, Kazlauskas A.

Biosci Rep. 2012 Aug;32(4):393-400. doi: 10.1042/BSR20120033.

43.

Dual-modality fluorescence and full-field optical coherence microscopy for biomedical imaging applications.

Auksorius E, Bromberg Y, Motiejūnaitė R, Pieretti A, Liu L, Coron E, Aranda J, Goldstein AM, Bouma BE, Kazlauskas A, Tearney GJ.

Biomed Opt Express. 2012 Mar 1;3(3):661-6. doi: 10.1364/BOE.3.000661. Epub 2012 Feb 27.

45.

Diabetes disrupts the response of retinal endothelial cells to the angiomodulator lysophosphatidic acid.

Aranda J, Motiejunaite R, Im E, Kazlauskas A.

Diabetes. 2012 May;61(5):1225-33. doi: 10.2337/db11-1189. Epub 2012 Mar 13.

46.

Axl is essential for VEGF-A-dependent activation of PI3K/Akt.

Ruan GX, Kazlauskas A.

EMBO J. 2012 Apr 4;31(7):1692-703. doi: 10.1038/emboj.2012.21. Epub 2012 Feb 10.

47.

SH3 domain-mediated recruitment of host cell amphiphysins by alphavirus nsP3 promotes viral RNA replication.

Neuvonen M, Kazlauskas A, Martikainen M, Hinkkanen A, Ahola T, Saksela K.

PLoS Pathog. 2011 Nov;7(11):e1002383. doi: 10.1371/journal.ppat.1002383. Epub 2011 Nov 17.

48.

A novel strategy to develop therapeutic approaches to prevent proliferative vitreoretinopathy.

Pennock S, Rheaume MA, Mukai S, Kazlauskas A.

Am J Pathol. 2011 Dec;179(6):2931-40. doi: 10.1016/j.ajpath.2011.08.043. Epub 2011 Oct 28.

49.

Cambogin is preferentially cytotoxic to cells expressing PDGFR.

Tian Z, Shen J, Wang F, Xiao P, Yang J, Lei H, Kazlauskas A, Kohane IS, Wu E.

PLoS One. 2011;6(6):e21370. doi: 10.1371/journal.pone.0021370. Epub 2011 Jun 21.

50.

[Viral vectors for gene delivery to corneal endothelial cells].

Fuchsluger TA, Jurkunas U, Kazlauskas A, Dana R.

Klin Monbl Augenheilkd. 2011 Jun;228(6):498-503. doi: 10.1055/s-0031-1273399. Epub 2011 Jun 7. German.

PMID:
21656431

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