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Items: 25


Implications of Epigenetic Drift in Colorectal Neoplasia.

Luebeck GE, Hazelton WD, Curtius K, Maden SK, Yu M, Carter KT, Burke W, Lampe PD, Li CI, Ulrich CM, Newcomb PA, Westerhoff M, Kaz AM, Luo Y, Inadomi JM, Grady WM.

Cancer Res. 2019 Feb 1;79(3):495-504. doi: 10.1158/0008-5472.CAN-18-1682. Epub 2018 Oct 5.


Subtypes of Barrett's oesophagus and oesophageal adenocarcinoma based on genome-wide methylation analysis.

Yu M, Maden SK, Stachler M, Kaz AM, Ayers J, Guo Y, Carter KT, Willbanks A, Heinzerling TJ, O'Leary RM, Xu X, Bass A, Chandar AK, Chak A, Elliott R, Willis JE, Markowitz SD, Grady WM.

Gut. 2018 Jun 8. pii: gutjnl-2017-314544. doi: 10.1136/gutjnl-2017-314544. [Epub ahead of print]


Editorial: The Name Game: Circumventing Quality Metrics by Categorizing Incomplete Colonoscopy as Sigmoidoscopy.

Kaz AM, Dominitz JA.

Am J Gastroenterol. 2017 Oct;112(10):1553-1555. doi: 10.1038/ajg.2017.258.


BVES regulates c-Myc stability via PP2A and suppresses colitis-induced tumourigenesis.

Parang B, Kaz AM, Barrett CW, Short SP, Ning W, Keating CE, Mittal MK, Naik RD, Washington MK, Revetta FL, Smith JJ, Chen X, Wilson KT, Brand T, Bader DM, Tansey WP, Chen R, Brentnall TA, Grady WM, Williams CS.

Gut. 2017 May;66(5):852-862. doi: 10.1136/gutjnl-2015-310255. Epub 2016 Jan 14.


Erratum to: Global DNA methylation patterns in Barrett's esophagus, dysplastic Barrett's, and esophageal adenocarcinoma are associated with BMI, gender, and tobacco use.

Kaz AM, Wong CJ, Varadan V, Willis JE, Chak A, Grady WM.

Clin Epigenetics. 2017 Mar 1;9:23. doi: 10.1186/s13148-017-0324-8. eCollection 2017.


Anal intraepithelial neoplasia: A review of diagnosis and management.

Roberts JR, Siekas LL, Kaz AM.

World J Gastrointest Oncol. 2017 Feb 15;9(2):50-61. doi: 10.4251/wjgo.v9.i2.50. Review.


Epigenetic silencing of TPM2 contributes to colorectal cancer progression upon RhoA activation.

Cui J, Cai Y, Hu Y, Huang Z, Luo Y, Kaz AM, Yang Z, Chen D, Fan X, Grady WM, Wang J.

Tumour Biol. 2016 Sep;37(9):12477-12483. Epub 2016 Jun 23.


Comprehensive site-specific whole genome profiling of stromal and epithelial colonic gene signatures in human sigmoid colon and rectal tissue.

Knight JM, Kim E, Ivanov I, Davidson LA, Goldsby JS, Hullar MA, Randolph TW, Kaz AM, Levy L, Lampe JW, Chapkin RS.

Physiol Genomics. 2016 Sep 1;48(9):651-9. doi: 10.1152/physiolgenomics.00023.2016. Epub 2016 Jul 8.


A Molecular Clock Infers Heterogeneous Tissue Age Among Patients with Barrett's Esophagus.

Curtius K, Wong CJ, Hazelton WD, Kaz AM, Chak A, Willis JE, Grady WM, Luebeck EG.

PLoS Comput Biol. 2016 May 11;12(5):e1004919. doi: 10.1371/journal.pcbi.1004919. eCollection 2016 May. Erratum in: PLoS Comput Biol. 2017 Mar 17;13(3):e1005439.


Can individuals with colonic polyposis be managed safely with colonoscopic surveillance?

Kaz AM, Dominitz JA.

Endoscopy. 2016 Jan;48(1):7-8. doi: 10.1055/s-0034-1393637. Epub 2015 Dec 28. No abstract available.


Universal Screening of Colorectal Cancers for Lynch Syndrome: Challenges and Opportunities.

Vindigni SM, Kaz AM.

Dig Dis Sci. 2016 Apr;61(4):969-76. doi: 10.1007/s10620-015-3964-6. Epub 2015 Nov 24. Review.


Methylated B3GAT2 and ZNF793 Are Potential Detection Biomarkers for Barrett's Esophagus.

Yu M, O'Leary RM, Kaz AM, Morris SM, Carter KT, Chak A, Chandar A, Willis JE, Moinova HR, Markowitz SD, Brenner DE, Anandabapasathy S, Westerhoff M, Wong CJ, Shaheen NJ, Chen Y, Barnholtz-Sloan JS, Grady WM.

Cancer Epidemiol Biomarkers Prev. 2015 Dec;24(12):1890-7. doi: 10.1158/1055-9965.EPI-15-0370. Epub 2015 Nov 6.


Use of a novel polyp "ruler snare" improves estimation of colon polyp size.

Kaz AM, Anwar A, O'Neill DR, Dominitz JA.

Gastrointest Endosc. 2016 Apr;83(4):812-6. doi: 10.1016/j.gie.2015.08.082. Epub 2015 Sep 14.


Genetic and Epigenetic Alterations in Barrett's Esophagus and Esophageal Adenocarcinoma.

Kaz AM, Grady WM, Stachler MD, Bass AJ.

Gastroenterol Clin North Am. 2015 Jun;44(2):473-89. doi: 10.1016/j.gtc.2015.02.015. Epub 2015 Apr 1. Review.


Differences in DNA methylation signatures reveal multiple pathways of progression from adenoma to colorectal cancer.

Luo Y, Wong CJ, Kaz AM, Dzieciatkowski S, Carter KT, Morris SM, Wang J, Willis JE, Makar KW, Ulrich CM, Lutterbaugh JD, Shrubsole MJ, Zheng W, Markowitz SD, Grady WM.

Gastroenterology. 2014 Aug;147(2):418-29.e8. doi: 10.1053/j.gastro.2014.04.039. Epub 2014 Apr 30.


Patterns of DNA methylation in the normal colon vary by anatomical location, gender, and age.

Kaz AM, Wong CJ, Dzieciatkowski S, Luo Y, Schoen RE, Grady WM.

Epigenetics. 2014 Apr;9(4):492-502. doi: 10.4161/epi.27650. Epub 2014 Jan 10.


NTRK3 is a potential tumor suppressor gene commonly inactivated by epigenetic mechanisms in colorectal cancer.

Luo Y, Kaz AM, Kanngurn S, Welsch P, Morris SM, Wang J, Lutterbaugh JD, Markowitz SD, Grady WM.

PLoS Genet. 2013;9(7):e1003552. doi: 10.1371/journal.pgen.1003552. Epub 2013 Jul 11.


Epigenetic biomarkers in esophageal cancer.

Kaz AM, Grady WM.

Cancer Lett. 2014 Jan 28;342(2):193-9. doi: 10.1016/j.canlet.2012.02.036. Epub 2012 Mar 7. Review.


Aberrantly methylated PKP1 in the progression of Barrett's esophagus to esophageal adenocarcinoma.

Kaz AM, Luo Y, Dzieciatkowski S, Chak A, Willis JE, Upton MP, Leidner RS, Grady WM.

Genes Chromosomes Cancer. 2012 Apr;51(4):384-93. doi: 10.1002/gcc.21923. Epub 2011 Dec 14.


DNA methylation profiling in Barrett's esophagus and esophageal adenocarcinoma reveals unique methylation signatures and molecular subclasses.

Kaz AM, Wong CJ, Luo Y, Virgin JB, Washington MK, Willis JE, Leidner RS, Chak A, Grady WM.

Epigenetics. 2011 Dec;6(12):1403-12. doi: 10.4161/epi.6.12.18199.


Epigenetic silencing of the intronic microRNA hsa-miR-342 and its host gene EVL in colorectal cancer.

Grady WM, Parkin RK, Mitchell PS, Lee JH, Kim YH, Tsuchiya KD, Washington MK, Paraskeva C, Willson JK, Kaz AM, Kroh EM, Allen A, Fritz BR, Markowitz SD, Tewari M.

Oncogene. 2008 Jun 19;27(27):3880-8. doi: 10.1038/onc.2008.10. Epub 2008 Feb 11.


Genetic testing for colon cancer.

Kaz AM, Brentnall TA.

Nat Clin Pract Gastroenterol Hepatol. 2006 Dec;3(12):670-9. Review.


Oxygen regulation of tumor perfusion by S-nitrosohemoglobin reveals a pressor activity of nitric oxide.

Sonveaux P, Kaz AM, Snyder SA, Richardson RA, Cárdenas-Navia LI, Braun RD, Pawloski JR, Tozer GM, Bonaventura J, McMahon TJ, Stamler JS, Dewhirst MW.

Circ Res. 2005 May 27;96(10):1119-26. Epub 2005 May 5.


Protein kinase A regulates ATP hydrolysis and dimerization by a CFTR (cystic fibrosis transmembrane conductance regulator) domain.

Howell LD, Borchardt R, Kole J, Kaz AM, Randak C, Cohn JA.

Biochem J. 2004 Feb 15;378(Pt 1):151-9.

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