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A prospective study of the incidence, associations and outcomes of ocular surface squamous neoplasia in the United Kingdom.

Kiire CA, Stewart RMK, Srinivasan S, Heimann H, Kaye SB, Dhillon B.

Eye (Lond). 2018 Dec 28. doi: 10.1038/s41433-018-0217-x. [Epub ahead of print]


Cross-Country Transportation Efficacy and Clinical Outcomes of Preloaded Large-Diameter Ultra-Thin Descemet Stripping Automated Endothelial Keratoplasty Grafts.

Parekh M, Ruzza A, Steger B, Willoughby CE, Rehman S, Ferrari S, Ponzin D, Kaye SB, Romano V.

Cornea. 2019 Jan;38(1):30-34. doi: 10.1097/ICO.0000000000001777.


Functional Staging of Corneal Neovascularization Using Fluorescein and Indocyanine Green Angiography.

Palme C, Romano V, Brunner M, Vinciguerra R, Kaye SB, Steger B.

Transl Vis Sci Technol. 2018 Oct 1;7(5):15. doi: 10.1167/tvst.7.5.15. eCollection 2018 Sep.


Descemet Membrane Endothelial Keratoplasty - Complication and management of a single case for tissue preparation and graft size linked to post-op descemetorhexis disparity.

Parekh M, Ruzza A, Kaye A, Steger B, Kaye SB, Romano V.

Am J Ophthalmol Case Rep. 2018 Sep 6;12:65-67. doi: 10.1016/j.ajoc.2018.09.003. eCollection 2018 Dec.


Improving precision for detecting change in the shape of the cornea in patients with keratoconus.

Brunner M, Czanner G, Vinciguerra R, Romano V, Ahmad S, Batterbury M, Britten C, Willoughby CE, Kaye SB.

Sci Rep. 2018 Aug 17;8(1):12345. doi: 10.1038/s41598-018-30173-7.


Effect of storage time and temperature on the detection of Pseudomonas aeruginosa, Acanthamoeba and Herpes Simplex Virus from corneal impression membranes.

Somerville TF, Corless CE, Neal T, Kaye SB.

J Med Microbiol. 2018 Sep;67(9):1321-1325. doi: 10.1099/jmm.0.000812. Epub 2018 Jul 27.


Clinical outcomes of adolescents and young adults with advanced solid tumours participating in phase I trials.

Sundar R, McVeigh T, Dolling D, Petruckevitch A, Diamantis N, Ang JE, Chenard-Poiriér M, Collins D, Lim J, Ameratunga M, Khan K, Kaye SB, Banerji U, Lopez J, George AJ, de Bono JS, van der Graaf WT.

Eur J Cancer. 2018 Sep;101:55-61. doi: 10.1016/j.ejca.2018.06.003. Epub 2018 Jul 17.


Imaging of Corneal Neovascularization: Optical Coherence Tomography Angiography and Fluorescence Angiography.

Brunner M, Romano V, Steger B, Vinciguerra R, Lawman S, Williams B, Hicks N, Czanner G, Zheng Y, Willoughby CE, Kaye SB.

Invest Ophthalmol Vis Sci. 2018 Mar 1;59(3):1263-1269. doi: 10.1167/iovs.17-22035.


The role of genomic profiling in adolescents and young adults (AYAs) with advanced cancer participating in phase I clinical trials.

McVeigh TP, Sundar R, Diamantis N, Kaye SB, Banerji U, Lopez JS, de Bono J, van der Graaf WTA, George AJ.

Eur J Cancer. 2018 May;95:20-29. doi: 10.1016/j.ejca.2018.02.028. Epub 2018 Mar 31.


Progression of Keratoconus in Patients While Awaiting Corneal Cross-linking: A Prospective Clinical Study.

Romano V, Vinciguerra R, Arbabi EM, Hicks N, Rosetta P, Vinciguerra P, Kaye SB.

J Refract Surg. 2018 Mar 1;34(3):177-180. doi: 10.3928/1081597X-20180104-01.


Possible Role of Descemet-Stroma Interface for Descemet's Membrane Detachment after Penetrating Keratoplasty.

Ho VW, Romano V, Steger B, Kaye SB.

J Ophthalmic Vis Res. 2018 Jan-Mar;13(1):72-74. doi: 10.4103/jovr.jovr_40_16.


Detection and Imaging of Lymphatic and Other Vessels in Corneal Neovascular Complexes.

Romano V, Steger B, Kaye SB.

Cornea. 2018 Apr;37(4):e22-e23. doi: 10.1097/ICO.0000000000001516. No abstract available.


Deformation velocity imaging using optical coherence tomography and its applications to the cornea.

Lawman S, Madden PW, Romano V, Dong Y, Mason S, Williams BM, Kaye SB, Willoughby CE, Harding SP, Shen YC, Zheng Y.

Biomed Opt Express. 2017 Nov 13;8(12):5579-5593. doi: 10.1364/BOE.8.005579. eCollection 2017 Dec 1.


High frequency of radiological differential responses with poly(ADP-Ribose) polymerase (PARP) inhibitor therapy.

Perez-Lopez R, Roda D, Jimenez B, Brown J, Mateo J, Carreira S, Lopez J, Banerji U, Molife LR, Koh DM, Kaye SB, de Bono JS, Tunariu N, Yap TA.

Oncotarget. 2017 Nov 6;8(61):104430-104443. doi: 10.18632/oncotarget.22303. eCollection 2017 Nov 28.


In Vivo Early Corneal Biomechanical Changes After Corneal Cross-linking in Patients With Progressive Keratoconus.

Vinciguerra R, Romano V, Arbabi EM, Brunner M, Willoughby CE, Batterbury M, Kaye SB.

J Refract Surg. 2017 Dec 1;33(12):840-846. doi: 10.3928/1081597X-20170922-02.


Clinical Outcome of Patients with Advanced Biliary Tract Cancer in a Dedicated Phase I Unit.

Sundar R, Custodio A, Petruckevich A, Chénard-Poirier M, Ameratunga M, Collins D, Lim J, Kaye SB, Tunariu N, Banerji U, de Bono J, Lopez J.

Clin Oncol (R Coll Radiol). 2018 Mar;30(3):185-191. doi: 10.1016/j.clon.2017.11.011. Epub 2017 Dec 7.


The Royal College of Ophthalmologists guidelines on serum eye drops for the treatment of severe ocular surface disease: full report.

Rauz S, Koay SY, Foot B, Kaye SB, Figueiredo F, Burdon MA, Dancey E, Chandrasekar A, Lomas R.

Eye (Lond). 2017 Nov 17. doi: 10.1038/eye.2017.209. [Epub ahead of print] No abstract available.


The Royal College of Ophthalmologists guidelines on serum eye drops for the treatment of severe ocular surface disease: executive summary.

Rauz S, Koay SY, Foot B, Kaye SB, Figueiredo F, Burdon MA, Dancey E, Chandrasekar A, Lomas R.

Eye (Lond). 2018 Jan;32(1):44-48. doi: 10.1038/eye.2017.208. Epub 2017 Nov 17. Review. No abstract available.


Artificial Anterior Chamber Pressure and Corneal Thinning Rate in UT-DSAEK.

Parekh M, Ruzza A, Borroni D, Kaye SB, Romano V.

Cornea. 2018 Feb;37(2):e5. doi: 10.1097/ICO.0000000000001464. No abstract available.


Comparison of preservation and transportation protocols for preloaded Descemet membrane endothelial keratoplasty.

Romano V, Parekh M, Ruzza A, Willoughby CE, Ferrari S, Ponzin D, Kaye SB, Levis HJ.

Br J Ophthalmol. 2018 Apr;102(4):549-555. doi: 10.1136/bjophthalmol-2017-310906. Epub 2017 Nov 13.


Identification of Feeder Vessels in Ocular Surface Neoplasia Using Indocyanine Green Angiography.

Brunner M, Steger B, Romano V, Hodson M, Zheng Y, Heimann H, Kaye SB.

Curr Eye Res. 2018 Feb;43(2):163-169. doi: 10.1080/02713683.2017.1387273. Epub 2017 Nov 7.


Detecting Change in Conjunctival Hyperemia Using a Pixel Densitometry Index.

Romano V, Steger B, Brunner M, Kaye A, Zheng Y, Willoughby CE, Kaye SB.

Ocul Immunol Inflamm. 2017 Nov 2:1-6. doi: 10.1080/09273948.2017.1387276. [Epub ahead of print]


Gene-based antiangiogenic applications for corneal neovascularization.

Liu S, Romano V, Steger B, Kaye SB, Hamill KJ, Willoughby CE.

Surv Ophthalmol. 2018 Mar - Apr;63(2):193-213. doi: 10.1016/j.survophthal.2017.10.006. Epub 2017 Nov 15. Review.


Phase I clinical trials in patients with advanced non-small cell lung cancer treated within a Drug Development Unit: What have we learnt?

Capelan M, Roda D, Geuna E, Rihawi K, Bodla S, Kaye SB, Bhosle J, Banerji U, O'Brien M, de Bono JS, Popat S, Yap TA.

Lung Cancer. 2017 Sep;111:6-11. doi: 10.1016/j.lungcan.2017.06.005. Epub 2017 Jun 15.


Indolent peritoneal mesothelioma: PI3K-mTOR inhibitors as a novel therapeutic strategy.

Dolly SO, Migali C, Tunariu N, Della-Pepa C, Khakoo S, Hazell S, de Bono JS, Kaye SB, Banerjee S.

ESMO Open. 2017 Apr 12;2(1):e000101. doi: 10.1136/esmoopen-2016-000101. eCollection 2017.


HIV-positive pregnant women attending the prevention of mother-to-child transmission of HIV/AIDS (PMTCT) services in Ethiopia: economic productivity losses across urban-rural settings.

Zegeye EA, Mbonigaba J, Kaye SB.

Psychol Health Med. 2018 Jun;23(5):525-531. doi: 10.1080/13548506.2017.1360469. Epub 2017 Jul 31.


Modulation of Plasma Metabolite Biomarkers of the MAPK Pathway with MEK Inhibitor RO4987655: Pharmacodynamic and Predictive Potential in Metastatic Melanoma.

Ang JE, Pal A, Asad YJ, Henley AT, Valenti M, Box G, de Haven Brandon A, Revell VL, Skene DJ, Venturi M, Rueger R, Meresse V, Eccles SA, de Bono JS, Kaye SB, Workman P, Banerji U, Raynaud FI.

Mol Cancer Ther. 2017 Oct;16(10):2315-2323. doi: 10.1158/1535-7163.MCT-16-0881. Epub 2017 Jun 21.


Baseline clinical predictors of antitumor response to the PARP inhibitor olaparib in germline BRCA1/2 mutated patients with advanced ovarian cancer.

Rafii S, Gourley C, Kumar R, Geuna E, Ern Ang J, Rye T, Chen LM, Shapira-Frommer R, Friedlander M, Matulonis U, De Greve J, Oza AM, Banerjee S, Molife LR, Gore ME, Kaye SB, Yap TA.

Oncotarget. 2017 Jul 18;8(29):47154-47160. doi: 10.18632/oncotarget.17005.


Preparation of ultrathin grafts for Descemet-stripping endothelial keratoplasty with a single microkeratome pass.

Romano V, Steger B, Myneni J, Batterbury M, Willoughby CE, Kaye SB.

J Cataract Refract Surg. 2017 Jan;43(1):12-15. doi: 10.1016/j.jcrs.2016.12.009.


Outcome of Descemet stripping automated endothelial keratoplasty in eyes with an Ahmed glaucoma valve.

Chiam PJ, Cheeseman R, Ho VW, Romano V, Choudhary A, Batterbury M, Kaye SB, Willoughby CE.

Graefes Arch Clin Exp Ophthalmol. 2017 May;255(5):987-993. doi: 10.1007/s00417-017-3612-2. Epub 2017 Mar 17.


Clinical factors of response in patients with advanced ovarian cancer participating in early phase clinical trials.

George A, Kristeleit R, Rafii S, Michie CO, Bowen R, Michalarea V, van Hagen T, Wong M, Rallis G, Molife LR, Lopez J, Banerji U, Banerjee SN, Gore ME, de Bono JS, Kaye SB, Yap TA.

Eur J Cancer. 2017 May;76:52-59. doi: 10.1016/j.ejca.2017.01.020. Epub 2017 Mar 6.


Avoiding Complications Associated With Preloaded Ultrathin Descemet Stripping Automated Endothelial Keratoplasty.

Parekh M, Ruzza A, Steger B, Willoughby CE, Ferrari S, Ponzin D, Kaye SB, Romano V.

Cornea. 2017 Apr;36(4):e12-e13. doi: 10.1097/ICO.0000000000001156. No abstract available.


Development of decellularized conjunctiva as a substrate for the ex vivo expansion of conjunctival epithelium.

Kasbekar S, Kaye SB, Williams RL, Stewart RMK, Leow-Dyke S, Rooney P.

J Tissue Eng Regen Med. 2018 Feb;12(2):e973-e982. doi: 10.1002/term.2419. Epub 2017 Jun 12.


Angiographic Evaluation of Inflammation in Atopic Keratoconjunctivitis.

Steger B, Romano V, Kaye SB.

Ocul Immunol Inflamm. 2018;26(5):685-688. doi: 10.1080/09273948.2016.1247873. Epub 2016 Nov 30.


Intraoperative management of macroperforations of Descemet's membrane in deep anterior lamellar keratoplasty.

Steger B, Romano V, Palme C, Kaye SB.

Spektrum Augenheilkd. 2016;30(4):175-180. Epub 2016 Oct 5.


Further evidence for heredity of pterygium.

Romano V, Steger B, Kovacova A, Kaye SB, Willoughby CE.

Ophthalmic Genet. 2016 Dec;37(4):434-436. Epub 2016 Mar 2.


Trabectedin as a chemotherapy option for patients with BRCA deficiency.

Monk BJ, Lorusso D, Italiano A, Kaye SB, Aracil M, Tanović A, D'Incalci M.

Cancer Treat Rev. 2016 Nov;50:175-182. doi: 10.1016/j.ctrv.2016.09.009. Epub 2016 Sep 15. Review.


Combined Use of Rituximab and Intravenous Immunoglobulin for Severe Autoimmune Cicatricial Conjunctivitis-An Interventional Case Series.

Steger B, Madhusudan S, Kaye SB, Stylianides A, Romano V, Maqsood SE, Harper J, Ahmad S.

Cornea. 2016 Dec;35(12):1611-1614. doi: 10.1097/ICO.0000000000001024.


Economic Evaluation in Ethiopian Healthcare Sector Decision Making: Perception, Practice and Barriers.

Zegeye EA, Mbonigaba J, Kaye SB, Wilkinson T.

Appl Health Econ Health Policy. 2017 Feb;15(1):33-43. doi: 10.1007/s40258-016-0280-z.


Facilitating a close interaction between basic, translational and clinical science: BMJ Open Ophthalmology.

Willoughby CE, Kaye SB.

BMJ Open Ophthalmol. 2016 Sep 6;1(1):e000001. doi: 10.1136/bmjophth-2016-000001. eCollection 2017. No abstract available.


Morphometric characterisation of pterygium associated with corneal stromal scarring using high-resolution anterior segment optical coherence tomography.

Gasser T, Romano V, Seifarth C, Bechrakis NE, Kaye SB, Steger B.

Br J Ophthalmol. 2017 May;101(5):660-664. doi: 10.1136/bjophthalmol-2016-308685. Epub 2016 Aug 3.


Yield and Viability of Human Limbal Stem Cells From Fresh and Stored Tissue.

Mason SL, Stewart RM, Sheridan CM, Keshtkar F, Rooney P, Austin E, Schlötzer-Schrehardt U, Kruse FE, Kaye SB.

Invest Ophthalmol Vis Sci. 2016 Jul 1;57(8):3708-13. doi: 10.1167/iovs.16-19354.


The Influence of Donor and Recipient Gender Incompatibility on Corneal Transplant Rejection and Failure.

Hopkinson CL, Romano V, Kaye RA, Steger B, Stewart RM, Tsagkataki M, Jones MN, Larkin DF, Kaye SB; National Health Service Blood Transplant Ocular Tissue Advisory Group and Contributing Ophthalmologists (OTAG Study 20).

Am J Transplant. 2017 Jan;17(1):210-217. doi: 10.1111/ajt.13926. Epub 2016 Jul 22.


An Adaptive Study to Determine the Optimal Dose of the Tablet Formulation of the PARP Inhibitor Olaparib.

Mateo J, Moreno V, Gupta A, Kaye SB, Dean E, Middleton MR, Friedlander M, Gourley C, Plummer R, Rustin G, Sessa C, Leunen K, Ledermann J, Swaisland H, Fielding A, Bannister W, Nicum S, Molife LR.

Target Oncol. 2016 Jun;11(3):401-15. doi: 10.1007/s11523-016-0435-8.


Method for Angiographically Guided Fine-Needle Diathermy in the Treatment of Corneal Neovascularization.

Romano V, Steger B, Brunner M, Ahmad S, Willoughby CE, Kaye SB.

Cornea. 2016 Jul;35(7):1029-32. doi: 10.1097/ICO.0000000000000865.


Progress in the treatment of ovarian cancer-lessons from homologous recombination deficiency-the first 10 years.

Kaye SB.

Ann Oncol. 2016 Apr;27 Suppl 1:i1-i3. doi: 10.1093/annonc/mdw082. Review.


Plasma Metabolomic Changes following PI3K Inhibition as Pharmacodynamic Biomarkers: Preclinical Discovery to Phase I Trial Evaluation.

Ang JE, Pandher R, Ang JC, Asad YJ, Henley AT, Valenti M, Box G, de Haven Brandon A, Baird RD, Friedman L, Derynck M, Vanhaesebroeck B, Eccles SA, Kaye SB, Workman P, de Bono JS, Raynaud FI.

Mol Cancer Ther. 2016 Jun;15(6):1412-24. doi: 10.1158/1535-7163.MCT-15-0815. Epub 2016 Apr 5.


BRCA somatic mutations and epigenetic BRCA modifications in serous ovarian cancer.

Moschetta M, George A, Kaye SB, Banerjee S.

Ann Oncol. 2016 Aug;27(8):1449-55. doi: 10.1093/annonc/mdw142. Epub 2016 Mar 31. Review.


Cediranib in patients with relapsed platinum-sensitive ovarian cancer (ICON6): a randomised, double-blind, placebo-controlled phase 3 trial.

Ledermann JA, Embleton AC, Raja F, Perren TJ, Jayson GC, Rustin GJS, Kaye SB, Hirte H, Eisenhauer E, Vaughan M, Friedlander M, González-Martín A, Stark D, Clark E, Farrelly L, Swart AM, Cook A, Kaplan RS, Parmar MKB; ICON6 collaborators.

Lancet. 2016 Mar 12;387(10023):1066-1074. doi: 10.1016/S0140-6736(15)01167-8. Erratum in: Lancet. 2016 Apr 23;387(10029):1722.

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