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Items: 1 to 50 of 248

1.

Failure to Rescue as an Outcome Metric for Pediatric and Congenital Cardiac Catheterization Laboratory Programs: Analysis of Data From the IMPACT Registry.

O'Byrne ML, Kennedy KF, Jayaram N, Bergersen LJ, Gillespie MJ, Dori Y, Silber JH, Kawut SM, Rome JJ, Glatz AC.

J Am Heart Assoc. 2019 Nov 5;8(21):e013151. doi: 10.1161/JAHA.119.013151. Epub 2019 Oct 17.

PMID:
31619106
2.

2-Year Outcomes After Complete or Staged Procedure for Tetralogy of Fallot in Neonates.

Savla JJ, Faerber JA, Huang YV, Zaoutis T, Goldmuntz E, Kawut SM, Mercer-Rosa L.

J Am Coll Cardiol. 2019 Sep 24;74(12):1570-1579. doi: 10.1016/j.jacc.2019.05.057.

PMID:
31537267
3.

Endothelin-1, cardiac morphology, and heart failure: the MESA angiogenesis study.

Leary PJ, Jenny NS, Bluemke DA, Kawut SM, Kronmal RA, Lima JA, Maron BA, Ralph DD, Rayner SG, Ryan JJ, Steinberg ZL, Hinckley Stukovsky KD, Tedford RJ.

J Heart Lung Transplant. 2019 Aug 10. pii: S1053-2498(19)31618-3. doi: 10.1016/j.healun.2019.07.007. [Epub ahead of print]

PMID:
31515065
4.

The presence of Aspergillus fumigatus is associated with worse respiratory quality of life in cystic fibrosis.

Hong G, Alby K, Ng SCW, Fleck V, Kubrak C, Rubenstein RC, Dorgan DJ, Kawut SM, Hadjiliadis D.

J Cyst Fibros. 2019 Aug 21. pii: S1569-1993(19)30840-9. doi: 10.1016/j.jcf.2019.08.008. [Epub ahead of print]

PMID:
31446018
5.

Circulating adhesion molecules and subclinical interstitial lung disease: the Multi-Ethnic Study of Atherosclerosis.

McGroder CF, Aaron CP, Bielinski SJ, Kawut SM, Tracy RP, Raghu G, Barr RG, Lederer DJ, Podolanczuk AJ.

Eur Respir J. 2019 Sep 30;54(3). pii: 1900295. doi: 10.1183/13993003.00295-2019. Print 2019 Sep.

PMID:
31371443
6.

Predicting respiratory failure in amyotrophic lateral sclerosis: still a long way to go.

Ackrivo J, Elman L, Kawut SM.

Eur Respir J. 2019 Aug 1;54(2). pii: 1901221. doi: 10.1183/13993003.01221-2019. Print 2019 Aug. No abstract available.

PMID:
31371442
7.

Angiotensin Receptor Blockers and Subclinical Interstitial Lung Disease: The MESA Study.

Gannon WD, Anderson MR, Podolanczuk AJ, Kawut SM, Michos ED, Cottin V, Kreuter M, Raghu G, Barr RG, Lederer DJ.

Ann Am Thorac Soc. 2019 Jul 31. doi: 10.1513/AnnalsATS.201903-198RL. [Epub ahead of print] No abstract available.

PMID:
31365837
8.

Classifying Amyotrophic Lateral Sclerosis Patients by Changes in Forced Vital Capacity: A Group-Based Trajectory Analysis.

Ackrivo J, Hansen-Flaschen J, Jones BL, Wileyto EP, Schwab RJ, Elman L, Kawut SM.

Am J Respir Crit Care Med. 2019 Jul 19. doi: 10.1164/rccm.201902-0344OC. [Epub ahead of print]

PMID:
31322417
9.

Portopulmonary Hypertension: A Survey of Practice Patterns and Provider Attitudes.

DuBrock HM, Salgia RJ, Sussman NL, Bartolome SD, Kadry Z, Mulligan DC, Jenkins S, Lackore K, Channick RN, Kawut SM, Krowka MJ.

Transplant Direct. 2019 May 22;5(6):e456. doi: 10.1097/TXD.0000000000000900. eCollection 2019 Jun.

10.

Fulvestrant for the Treatment of Pulmonary Arterial Hypertension.

Kawut SM, Pinder D, Al-Naamani N, McCormick A, Palevsky HI, Fritz J, Smith KA, Mazurek JA, Doyle MF, MacLean MR, DeMichele A, Mankoff DA.

Ann Am Thorac Soc. 2019 Jul 17. doi: 10.1513/AnnalsATS.201904-328RL. [Epub ahead of print] No abstract available.

PMID:
31314997
11.

Response.

Klinger JR, Elliott G, Levine DJ, Bossone E, Duvall L, Fagan K, Frantsve-Hawley J, Kawut SM, Ryan JJ, Rosenzweig EB, Sederstrom N, Steen VD, Badesch DB.

Chest. 2019 Jul;156(1):187-188. doi: 10.1016/j.chest.2019.03.039. No abstract available.

PMID:
31279370
12.

Ambient air pollution and pulmonary vascular volume on computed tomography: the MESA Air Pollution and Lung cohort studies.

Aaron CP, Hoffman EA, Kawut SM, Austin JHM, Budoff M, Michos ED, Hinckley Stukovsky K, Sack C, Szpiro AA, Watson KD, Kaufman JD, Barr RG.

Eur Respir J. 2019 Jun 5;53(6). pii: 1802116. doi: 10.1183/13993003.02116-2018. Print 2019 Jun.

PMID:
31167881
13.

New Strategies for the Conduct of Clinical Trials in Pediatric Pulmonary Arterial Hypertension: Outcome of a Multistakeholder Meeting With Patients, Academia, Industry, and Regulators, Held at the European Medicines Agency on Monday, June 12, 2017.

Ollivier C, Sun H, Amchin W, Beghetti M, Berger RMF, Breitenstein S, Garnett C, Gullberg N, Hassel P, Ivy D, Kawut SM, Klein A, Lesage C, Migdal M, Nije B, Odermarsky M, Strait J, de Graeff PA, Stockbridge N.

J Am Heart Assoc. 2019 May 21;8(10):e011306. doi: 10.1161/JAHA.118.011306. No abstract available.

14.

Interhospital Variation in the Costs of Pediatric/Congenital Cardiac Catheterization Laboratory Procedures: Analysis of Data From the Pediatric Health Information Systems Database.

O'Byrne ML, Glatz AC, Faerber JA, Seshadri R, Millenson ME, Mi L, Shinohara RT, Dori Y, Gillespie MJ, Rome JJ, Kawut SM, Groeneveld PW.

J Am Heart Assoc. 2019 May 7;8(9):e011543. doi: 10.1161/JAHA.118.011543.

15.

The Post-Pulmonary Embolism Syndrome: Real or Ruse?

Pugliese SC, Kawut SM.

Ann Am Thorac Soc. 2019 Jul;16(7):811-814. doi: 10.1513/AnnalsATS.201901-061PS. No abstract available.

PMID:
30974063
16.

EXPRESS: Statement on imaging and pulmonary hypertension from the Pulmonary Vascular Research Institute (PVRI).

Kiely DG, Levin D, Hassoun P, Ivy DD, Jone PN, Bwika J, Kawut SM, Lordan J, Lungu A, Mazurek J, Moledina S, Olschewski H, Peacock A, Puri GD, Rahaghi F, Schafer M, Schiebler M, Screaton N, Tawhai M, Van Beek EJ, Vonk-Noordegraaf A, Vanderpool RR, Wort J, Zhao L, Wild J, Vogel-Claussen J, Swift AJ.

Pulm Circ. 2019 Mar 18:2045894019841990. doi: 10.1177/2045894019841990. [Epub ahead of print] No abstract available.

17.

Right ventricular outflow tract velocity time integral-to-pulmonary artery systolic pressure ratio: a non-invasive metric of pulmonary arterial compliance differs across the spectrum of pulmonary hypertension.

Bhattacharya PT, Troutman GS, Mao F, Fox AL, Tanna MS, Zamani P, Grandin EW, Menachem JN, Birati EY, Chirinos JA, Mazimba S, Smith KA, Kawut SM, Forfia PR, Vaidya A, Mazurek JA.

Pulm Circ. 2019 Apr-Jun;9(2):2045894019841978. doi: 10.1177/2045894019841978.

18.

Sorafenib in Hepatopulmonary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial.

Kawut SM, Ellenberg SS, Krowka MJ, Goldberg D, Vargas H, Koch D, Sharkoski T, Al-Naamani N, Fox A, Brown R, Levitsky J, Oh JK, Lin G, Song N, Mottram C, Doyle MF, Kaplan DE, Gupta S, Fallon MB.

Liver Transpl. 2019 Aug;25(8):1155-1164. doi: 10.1002/lt.25438. Epub 2019 May 30.

PMID:
30816637
19.

Development of a prognostic model of respiratory insufficiency or death in amyotrophic lateral sclerosis.

Ackrivo J, Hansen-Flaschen J, Wileyto EP, Schwab RJ, Elman L, Kawut SM.

Eur Respir J. 2019 Apr 18;53(4). pii: 1802237. doi: 10.1183/13993003.02237-2018. Print 2019 Apr.

20.

Therapy for Pulmonary Arterial Hypertension in Adults: Update of the CHEST Guideline and Expert Panel Report.

Klinger JR, Elliott CG, Levine DJ, Bossone E, Duvall L, Fagan K, Frantsve-Hawley J, Kawut SM, Ryan JJ, Rosenzweig EB, Sederstrom N, Steen VD, Badesch DB.

Chest. 2019 Mar;155(3):565-586. doi: 10.1016/j.chest.2018.11.030. Epub 2019 Jan 17.

PMID:
30660783
21.

Inhaled antibiotic use is associated with Scedosporium/Lomentospora species isolation in cystic fibrosis.

Hong G, Lechtzin N, Hadjiliadis D, Kawut SM.

Pediatr Pulmonol. 2019 Feb;54(2):133-140. doi: 10.1002/ppul.24210. Epub 2018 Dec 14.

PMID:
30549449
22.

Pathophysiology of the right ventricle and of the pulmonary circulation in pulmonary hypertension: an update.

Vonk Noordegraaf A, Chin KM, Haddad F, Hassoun PM, Hemnes AR, Hopkins SR, Kawut SM, Langleben D, Lumens J, Naeije R.

Eur Respir J. 2019 Jan 24;53(1). pii: 1801900. doi: 10.1183/13993003.01900-2018. Print 2019 Jan.

23.

New and Emerging Therapies for Pulmonary Arterial Hypertension.

Spiekerkoetter E, Kawut SM, de Jesus Perez VA.

Annu Rev Med. 2019 Jan 27;70:45-59. doi: 10.1146/annurev-med-041717-085955. Epub 2018 Sep 14.

PMID:
30216732
24.

The Impact of Pulmonary Hypertension in Preterm Infants with Severe Bronchopulmonary Dysplasia through 1 Year.

Lagatta JM, Hysinger EB, Zaniletti I, Wymore EM, Vyas-Read S, Yallapragada S, Nelin LD, Truog WE, Padula MA, Porta NFM, Savani RC, Potoka KP, Kawut SM, DiGeronimo R, Natarajan G, Zhang H, Grover TR, Engle WA, Murthy K; Children's Hospital Neonatal Consortium Severe BPD Focus Group.

J Pediatr. 2018 Dec;203:218-224.e3. doi: 10.1016/j.jpeds.2018.07.035. Epub 2018 Aug 29.

PMID:
30172426
25.

Assessment of Right Ventricular Function in the Research Setting: Knowledge Gaps and Pathways Forward. An Official American Thoracic Society Research Statement.

Lahm T, Douglas IS, Archer SL, Bogaard HJ, Chesler NC, Haddad F, Hemnes AR, Kawut SM, Kline JA, Kolb TM, Mathai SC, Mercier O, Michelakis ED, Naeije R, Tuder RM, Ventetuolo CE, Vieillard-Baron A, Voelkel NF, Vonk-Noordegraaf A, Hassoun PM; American Thoracic Society Assembly on Pulmonary Circulation.

Am J Respir Crit Care Med. 2018 Aug 15;198(4):e15-e43. doi: 10.1164/rccm.201806-1160ST.

PMID:
30109950
26.

Pulse Oximetry Is Insensitive for Detection of Hepatopulmonary Syndrome in Patients Evaluated for Liver Transplantation.

Forde KA, Fallon MB, Krowka MJ, Sprys M, Goldberg DS, Krok KL, Patel M, Lin G, Oh JK, Mottram CD, Scanlon PD, Kawut SM; Pulmonary Vascular Complications of Liver Disease 2 Study Group.

Hepatology. 2019 Jan;69(1):270-281. doi: 10.1002/hep.30139. Epub 2018 Dec 18.

PMID:
30070715
27.

Collagen biomarkers and subclinical interstitial lung disease: The Multi-Ethnic Study of Atherosclerosis.

Madahar P, Duprez DA, Podolanczuk AJ, Bernstein EJ, Kawut SM, Raghu G, Barr RG, Gross MD, Jacobs DR Jr, Lederer DJ.

Respir Med. 2018 Jul;140:108-114. doi: 10.1016/j.rmed.2018.06.001. Epub 2018 Jun 6.

28.

Lower DHEA-S levels predict disease and worse outcomes in post-menopausal women with idiopathic, connective tissue disease- and congenital heart disease-associated pulmonary arterial hypertension.

Baird GL, Archer-Chicko C, Barr RG, Bluemke DA, Foderaro AE, Fritz JS, Hill NS, Kawut SM, Klinger JR, Lima JAC, Mullin CJ, Ouyang P, Palevsky HI, Palmisicano AJ, Pinder D, Preston IR, Roberts KE, Smith KA, Walsh T, Whittenhall M, Ventetuolo CE.

Eur Respir J. 2018 Jun 28;51(6). pii: 1800467. doi: 10.1183/13993003.00467-2018. Print 2018 Jun.

29.

Serum 25-Hydroxyvitamin D Concentrations Are Associated with Computed Tomography Markers of Subclinical Interstitial Lung Disease among Community-Dwelling Adults in the Multi-Ethnic Study of Atherosclerosis (MESA).

Kim SM, Zhao D, Podolanczuk AJ, Lutsey PL, Guallar E, Kawut SM, Barr RG, de Boer IH, Kestenbaum BR, Lederer DJ, Michos ED.

J Nutr. 2018 Jul 1;148(7):1126-1134. doi: 10.1093/jn/nxy066.

30.

Predictors of Length of Hospital Stay After Complete Repair for Tetralogy of Fallot: A Prospective Cohort Study.

Mercer-Rosa L, Elci OU, DeCost G, Woyciechowski S, Edman SM, Ravishankar C, Mascio CE, Kawut SM, Goldmuntz E.

J Am Heart Assoc. 2018 May 16;7(11). pii: e008719. doi: 10.1161/JAHA.118.008719.

31.

Right ventricular function mirrors clinical improvement with use of prostacyclin analogues in pediatric pulmonary hypertension.

Hopper RK, Wang Y, DeMatteo V, Santo A, Kawut SM, Elci OU, Hanna BD, Mercer-Rosa L.

Pulm Circ. 2018 Apr-Jun;8(2):2045894018759247. doi: 10.1177/2045894018759247. Epub 2018 Feb 26.

32.

Risk factors for persistent Aspergillus respiratory isolation in cystic fibrosis.

Hong G, Psoter KJ, Jennings MT, Merlo CA, Boyle MP, Hadjiliadis D, Kawut SM, Lechtzin N.

J Cyst Fibros. 2018 Sep;17(5):624-630. doi: 10.1016/j.jcf.2018.01.008. Epub 2018 Feb 12.

33.

Association of long pentraxin-3 with pulmonary hypertension and primary graft dysfunction in lung transplant recipients.

Diamond JM, Ramphal K, Porteous MK, Cantu E 3rd, Christie JD, Kawut SM; Lung Transplant Outcomes Group.

J Heart Lung Transplant. 2018 Jun;37(6):792-794. doi: 10.1016/j.healun.2017.12.012. Epub 2017 Dec 20. No abstract available.

34.

Cell-free hemoglobin promotes primary graft dysfunction through oxidative lung endothelial injury.

Shaver CM, Wickersham N, McNeil JB, Nagata H, Miller A, Landstreet SR, Kuck JL, Diamond JM, Lederer DJ, Kawut SM, Palmer SM, Wille KM, Weinacker A, Lama VN, Crespo MM, Orens JB, Shah PD, Hage CA, Cantu E 3rd, Porteous MK, Dhillon G, McDyer J, Bastarache JA, Christie JD, Ware LB; Lung Transplant Outcomes Group (LTOG).

JCI Insight. 2018 Jan 25;3(2). pii: 98546. doi: 10.1172/jci.insight.98546. eCollection 2018 Jan 25.

35.

Histamine H2 Receptor Polymorphisms, Myocardial Transcripts, and Heart Failure (from the Multi-Ethnic Study of Atherosclerosis and Beta-Blocker Effect on Remodeling and Gene Expression Trial).

Leary PJ, Kronmal RA, Bluemke DA, Buttrick PM, Jones KL, Kao DP, Kawut SM, Krieger EV, Lima JA, Minobe W, Ralph DD, Tedford RJ, Weiss NS, Bristow MR.

Am J Cardiol. 2018 Jan 15;121(2):256-261. doi: 10.1016/j.amjcard.2017.10.016. Epub 2017 Oct 20.

36.

Associations between emphysema-like lung on CT and incident airflow limitation: a general population-based cohort study.

Oelsner EC, Smith BM, Hoffman EA, Folsom AR, Kawut SM, Kaufman JD, Manichaikul A, Lederer DJ, Schwartz JE, Watson KE, Enright PL, Austin JHM, Lima JAC, Shea SJ, Barr RG.

Thorax. 2018 May;73(5):486-488. doi: 10.1136/thoraxjnl-2017-210842. Epub 2017 Oct 26.

37.

Health Disparities in Patients with Pulmonary Arterial Hypertension: A Blueprint for Action. An Official American Thoracic Society Statement.

Talwar A, Garcia JGN, Tsai H, Moreno M, Lahm T, Zamanian RT, Machado R, Kawut SM, Selej M, Mathai S, D'Anna LH, Sahni S, Rodriquez EJ, Channick R, Fagan K, Gray M, Armstrong J, Rodriguez Lopez J, de Jesus Perez V; Pulmonary Circulation Assembly.

Am J Respir Crit Care Med. 2017 Oct 15;196(8):e32-e47. doi: 10.1164/rccm.201709-1821ST. Review.

PMID:
29028375
38.

Clinical Impact of Intrapulmonary Vascular Dilatation in Candidates for Liver Transplant.

DuBrock HM, Krowka MJ, Forde KA, Krok K, Patel M, Sharkoski T, Sprys M, Lin G, Oh JK, Mottram CD, Scanlon PD, Fallon MB, Kawut SM.

Chest. 2018 Feb;153(2):414-426. doi: 10.1016/j.chest.2017.09.035. Epub 2017 Oct 5.

39.

Features and Outcomes of Methamphetamine-associated Pulmonary Arterial Hypertension.

Zamanian RT, Hedlin H, Greuenwald P, Wilson DM, Segal JI, Jorden M, Kudelko K, Liu J, Hsi A, Rupp A, Sweatt AJ, Tuder R, Berry GJ, Rabinovitch M, Doyle RL, de Jesus Perez V, Kawut SM.

Am J Respir Crit Care Med. 2018 Mar 15;197(6):788-800. doi: 10.1164/rccm.201705-0943OC.

40.

Quantitative Evidence for Revising the Definition of Primary Graft Dysfunction after Lung Transplant.

Cantu E, Diamond JM, Suzuki Y, Lasky J, Schaufler C, Lim B, Shah R, Porteous M, Lederer DJ, Kawut SM, Palmer SM, Snyder LD, Hartwig MG, Lama VN, Bhorade S, Bermudez C, Crespo M, McDyer J, Wille K, Orens J, Shah PD, Weinacker A, Weill D, Wilkes D, Roe D, Hage C, Ware LB, Bellamy SL, Christie JD; Lung Transplant Outcomes Group.

Am J Respir Crit Care Med. 2018 Jan 15;197(2):235-243. doi: 10.1164/rccm.201706-1140OC.

41.

Racial and ethnic differences in pulmonary arterial hypertension.

Al-Naamani N, Paulus JK, Roberts KE, Pauciulo MW, Lutz K, Nichols WC, Kawut SM.

Pulm Circ. 2017 Oct-Dec;7(4):793-796. doi: 10.1177/2045893217732213. Epub 2017 Sep 15.

42.

Report of the International Society for Heart and Lung Transplantation Working Group on Primary Lung Graft Dysfunction, part II: Epidemiology, risk factors, and outcomes-A 2016 Consensus Group statement of the International Society for Heart and Lung Transplantation.

Diamond JM, Arcasoy S, Kennedy CC, Eberlein M, Singer JP, Patterson GM, Edelman JD, Dhillon G, Pena T, Kawut SM, Lee JC, Girgis R, Dark J, Thabut G.

J Heart Lung Transplant. 2017 Oct;36(10):1104-1113. doi: 10.1016/j.healun.2017.07.020. Epub 2017 Jul 26. Review. No abstract available.

PMID:
28802530
43.

Inhibiting oestrogen signalling in pulmonary arterial hypertension: sex, drugs and research.

Lahm T, Kawut SM.

Eur Respir J. 2017 Aug 3;50(2). pii: 1700983. doi: 10.1183/13993003.00983-2017. Print 2017 Aug. No abstract available.

44.

Ambient Coarse Particulate Matter and the Right Ventricle: The Multi-Ethnic Study of Atherosclerosis.

D'Souza JC, Kawut SM, Elkayam LR, Sheppard L, Thorne PS, Jacobs DR Jr, Bluemke DA, Lima JAC, Kaufman JD, Larson TV, Adar SD.

Environ Health Perspect. 2017 Jul 27;125(7):077019. doi: 10.1289/EHP658.

45.

Occupational Exposures and Subclinical Interstitial Lung Disease. The MESA (Multi-Ethnic Study of Atherosclerosis) Air and Lung Studies.

Sack CS, Doney BC, Podolanczuk AJ, Hooper LG, Seixas NS, Hoffman EA, Kawut SM, Vedal S, Raghu G, Barr RG, Lederer DJ, Kaufman JD.

Am J Respir Crit Care Med. 2017 Oct 15;196(8):1031-1039. doi: 10.1164/rccm.201612-2431OC.

46.

Clinical Risk Factors and Prognostic Model for Primary Graft Dysfunction after Lung Transplantation in Patients with Pulmonary Hypertension.

Porteous MK, Lee JC, Lederer DJ, Palmer SM, Cantu E, Shah RJ, Bellamy SL, Lama VN, Bhorade SM, Crespo MM, McDyer JF, Wille KM, Localio AR, Orens JB, Shah PD, Weinacker AB, Arcasoy S, Wilkes DS, Ware LB, Christie JD, Kawut SM, Diamond JM; Lung Transplant Outcomes Group.

Ann Am Thorac Soc. 2017 Oct;14(10):1514-1522. doi: 10.1513/AnnalsATS.201610-810OC.

47.

Magnetic Resonance Imaging in Pulmonary Arterial Hypertension. Panacea or Pixelation?

Mathai SC, Kawut SM.

Am J Respir Crit Care Med. 2017 Jul 15;196(2):129-131. doi: 10.1164/rccm.201704-0721ED. No abstract available.

PMID:
28707971
48.

Tracheobronchomalacia Is Associated with Increased Morbidity in Bronchopulmonary Dysplasia.

Hysinger EB, Friedman NL, Padula MA, Shinohara RT, Zhang H, Panitch HB, Kawut SM; Children's Hospitals Neonatal Consortium.

Ann Am Thorac Soc. 2017 Sep 1;14(9). doi: 10.1513/AnnalsATS.201702-178OC. Epub 2017 Jun 16.

49.

Obstructive Sleep Apnea and Subclinical Interstitial Lung Disease in the Multi-Ethnic Study of Atherosclerosis (MESA).

Kim JS, Podolanczuk AJ, Borker P, Kawut SM, Raghu G, Kaufman JD, Stukovsky KDH, Hoffman EA, Barr RG, Gottlieb DJ, Redline SS, Lederer DJ.

Ann Am Thorac Soc. 2017 Dec;14(12):1786-1795. doi: 10.1513/AnnalsATS.201701-091OC.

50.

High-Attenuation Areas on Chest Computed Tomography and Clinical Respiratory Outcomes in Community-Dwelling Adults.

Podolanczuk AJ, Oelsner EC, Barr RG, Bernstein EJ, Hoffman EA, Easthausen IJ, Stukovsky KH, RoyChoudhury A, Michos ED, Raghu G, Kawut SM, Lederer DJ.

Am J Respir Crit Care Med. 2017 Dec 1;196(11):1434-1442. doi: 10.1164/rccm.201703-0555OC.

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