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Items: 1 to 50 of 57

1.

A germline HLTF mutation in familial MDS induces DNA damage accumulation through impaired PCNA polyubiquitination.

Takaoka K, Kawazu M, Koya J, Yoshimi A, Masamoto Y, Maki H, Toya T, Kobayashi T, Nannya Y, Arai S, Ueno T, Ueno H, Suzuki K, Harada H, Manabe A, Hayashi Y, Mano H, Kurokawa M.

Leukemia. 2019 Jan 29. doi: 10.1038/s41375-019-0385-0. [Epub ahead of print]

PMID:
30696947
2.

Differential regulation of CpG island-methylation within divergent and unidirectional promoters in colorectal cancer.

Namba S, Sato K, Kojima S, Ueno T, Yamamoto Y, Tanaka Y, Inoue S, Nagae G, Iinuma H, Hazama S, Ishihara S, Aburatani H, Mano H, Kawazu M.

Cancer Sci. 2019 Jan 13. doi: 10.1111/cas.13937. [Epub ahead of print]

3.

Fusion Kinases Identified by Genomic Analyses of Sporadic Microsatellite Instability-High Colorectal Cancers.

Sato K, Kawazu M, Yamamoto Y, Ueno T, Kojima S, Nagae G, Abe H, Soda M, Oga T, Kohsaka S, Sai E, Yamashita Y, Iinuma H, Fukayama M, Aburatani H, Watanabe T, Mano H.

Clin Cancer Res. 2019 Jan 1;25(1):378-389. doi: 10.1158/1078-0432.CCR-18-1574. Epub 2018 Oct 2.

PMID:
30279230
4.

Interrelation among the handling, mechanical, and wear properties of the newly developed flowable resin composites.

Imai A, Takamizawa T, Sugimura R, Tsujimoto A, Ishii R, Kawazu M, Saito T, Miyazaki M.

J Mech Behav Biomed Mater. 2019 Jan;89:72-80. doi: 10.1016/j.jmbbm.2018.09.019. Epub 2018 Sep 17.

PMID:
30265868
5.

JMJD2B/KDM4B inactivation in adipose tissues accelerates obesity and systemic metabolic abnormalities.

Kang C, Saso K, Ota K, Kawazu M, Ueda T, Okada H.

Genes Cells. 2018 Sep;23(9):767-777. doi: 10.1111/gtc.12627. Epub 2018 Aug 2.

PMID:
30073721
6.

Mutant ASXL1 cooperates with BAP1 to promote myeloid leukaemogenesis.

Asada S, Goyama S, Inoue D, Shikata S, Takeda R, Fukushima T, Yonezawa T, Fujino T, Hayashi Y, Kawabata KC, Fukuyama T, Tanaka Y, Yokoyama A, Yamazaki S, Kozuka-Hata H, Oyama M, Kojima S, Kawazu M, Mano H, Kitamura T.

Nat Commun. 2018 Jul 16;9(1):2733. doi: 10.1038/s41467-018-05085-9.

7.

High-Throughput Functional Evaluation of Variants of Unknown Significance in ERBB2.

Nagano M, Kohsaka S, Ueno T, Kojima S, Saka K, Iwase H, Kawazu M, Mano H.

Clin Cancer Res. 2018 Oct 15;24(20):5112-5122. doi: 10.1158/1078-0432.CCR-18-0991. Epub 2018 Jul 2.

PMID:
29967253
8.

Transcriptional activities of DUX4 fusions in B-cell acute lymphoblastic leukemia.

Tanaka Y, Kawazu M, Yasuda T, Tamura M, Hayakawa F, Kojima S, Ueno T, Kiyoi H, Naoe T, Mano H.

Haematologica. 2018 Nov;103(11):e522-e526. doi: 10.3324/haematol.2017.183152. Epub 2018 May 17. No abstract available.

9.

Inactivating mutations and hypermethylation of the NKX2-1/TTF-1 gene in non-terminal respiratory unit-type lung adenocarcinomas.

Matsubara D, Soda M, Yoshimoto T, Amano Y, Sakuma Y, Yamato A, Ueno T, Kojima S, Shibano T, Hosono Y, Kawazu M, Yamashita Y, Endo S, Hagiwara K, Fukayama M, Takahashi T, Mano H, Niki T.

Cancer Sci. 2017 Sep;108(9):1888-1896. doi: 10.1111/cas.13313. Epub 2017 Jul 29.

10.

Integrative analysis of genomic alterations in triple-negative breast cancer in association with homologous recombination deficiency.

Kawazu M, Kojima S, Ueno T, Totoki Y, Nakamura H, Kunita A, Qu W, Yoshimura J, Soda M, Yasuda T, Hama N, Saito-Adachi M, Sato K, Kohsaka S, Sai E, Ikemura M, Yamamoto S, Ogawa T, Fukayama M, Tada K, Seto Y, Morishita S, Hazama S, Shibata T, Yamashita Y, Mano H.

PLoS Genet. 2017 Jun 21;13(6):e1006853. doi: 10.1371/journal.pgen.1006853. eCollection 2017 Jun.

11.

Corrigendum: Recurrent DUX4 fusions in B cell acute lymphoblastic leukemia of adolescents and young adults.

Yasuda T, Tsuzuki S, Kawazu M, Hayakawa F, Kojima S, Ueno T, Imoto N, Kohsaka S, Kunita A, Doi K, Sakura T, Yujiri T, Kondo E, Fujimaki K, Ueda Y, Aoyama Y, Ohtake S, Takita J, Sai E, Taniwaki M, Kurokawa M, Morishita S, Fukayama M, Kiyoi H, Miyazaki Y, Naoe T, Mano H.

Nat Genet. 2016 Nov 29;48(12):1591. doi: 10.1038/ng1216-1587a. No abstract available.

PMID:
27898077
12.

Recurrent DUX4 fusions in B cell acute lymphoblastic leukemia of adolescents and young adults.

Yasuda T, Tsuzuki S, Kawazu M, Hayakawa F, Kojima S, Ueno T, Imoto N, Kohsaka S, Kunita A, Doi K, Sakura T, Yujiri T, Kondo E, Fujimaki K, Ueda Y, Aoyama Y, Ohtake S, Takita J, Sai E, Taniwaki M, Kurokawa M, Morishita S, Fukayama M, Kiyoi H, Miyazaki Y, Naoe T, Mano H.

Nat Genet. 2016 May;48(5):569-74. doi: 10.1038/ng.3535. Epub 2016 Mar 28. Erratum in: Nat Genet. 2016 Nov 29;48(12 ):1591.

PMID:
27019113
13.

Mutational Landscape and Antiproliferative Functions of ELF Transcription Factors in Human Cancer.

Ando M, Kawazu M, Ueno T, Koinuma D, Ando K, Koya J, Kataoka K, Yasuda T, Yamaguchi H, Fukumura K, Yamato A, Soda M, Sai E, Yamashita Y, Asakage T, Miyazaki Y, Kurokawa M, Miyazono K, Nimer SD, Yamasoba T, Mano H.

Cancer Res. 2016 Apr 1;76(7):1814-24. doi: 10.1158/0008-5472.CAN-14-3816. Epub 2016 Feb 26.

14.

Genomic characterization of primary central nervous system lymphoma.

Fukumura K, Kawazu M, Kojima S, Ueno T, Sai E, Soda M, Ueda H, Yasuda T, Yamaguchi H, Lee J, Shishido-Hara Y, Sasaki A, Shirahata M, Mishima K, Ichimura K, Mukasa A, Narita Y, Saito N, Aburatani H, Nishikawa R, Nagane M, Mano H.

Acta Neuropathol. 2016 Jun;131(6):865-75. doi: 10.1007/s00401-016-1536-2. Epub 2016 Jan 12.

PMID:
26757737
15.

Nephrology pre-dialysis care affects the psychological adjustment, not only blood pressure, anemia, and phosphorus control.

Furusho M, Kawazu M, Takeda K, Kurachi E, Nakashima T, Sagara R, Hara T, Mukai H, Miura S, Sugawara K.

Hemodial Int. 2015 Oct;19 Suppl 3:S2-4. doi: 10.1111/hdi.12345.

PMID:
26448382
16.

Transforming somatic mutations of mammalian target of rapamycin kinase in human cancer.

Yamaguchi H, Kawazu M, Yasuda T, Soda M, Ueno T, Kojima S, Yashiro M, Yoshino I, Ishikawa Y, Sai E, Mano H.

Cancer Sci. 2015 Dec;106(12):1687-92. doi: 10.1111/cas.12828. Epub 2015 Oct 30.

17.

Oncogenic activity of BIRC2 and BIRC3 mutants independent of nuclear factor-κB-activating potential.

Yamato A, Soda M, Ueno T, Kojima S, Sonehara K, Kawazu M, Sai E, Yamashita Y, Nagase T, Mano H.

Cancer Sci. 2015 Sep;106(9):1137-42. doi: 10.1111/cas.12726. Epub 2015 Jul 14.

18.

Recurrent CDC25C mutations drive malignant transformation in FPD/AML.

Yoshimi A, Toya T, Kawazu M, Ueno T, Tsukamoto A, Iizuka H, Nakagawa M, Nannya Y, Arai S, Harada H, Usuki K, Hayashi Y, Ito E, Kirito K, Nakajima H, Ichikawa M, Mano H, Kurokawa M.

Nat Commun. 2014 Aug 27;5:4770. doi: 10.1038/ncomms5770.

PMID:
25159113
19.

Detection of WIPI1 mRNA as an indicator of autophagosome formation.

Tsuyuki S, Takabayashi M, Kawazu M, Kudo K, Watanabe A, Nagata Y, Kusama Y, Yoshida K.

Autophagy. 2014 Mar;10(3):497-513. doi: 10.4161/auto.27419. Epub 2013 Dec 23.

20.

Leukemic evolution of donor-derived cells harboring IDH2 and DNMT3A mutations after allogeneic stem cell transplantation.

Yasuda T, Ueno T, Fukumura K, Yamato A, Ando M, Yamaguchi H, Soda M, Kawazu M, Sai E, Yamashita Y, Murata M, Kiyoi H, Naoe T, Mano H.

Leukemia. 2014 Feb;28(2):426-8. doi: 10.1038/leu.2013.278. Epub 2013 Sep 26. No abstract available.

PMID:
24067491
21.

STK10 missense mutations associated with anti-apoptotic function.

Fukumura K, Yamashita Y, Kawazu M, Sai E, Fujiwara S, Nakamura N, Takeuchi K, Ando M, Miyazono K, Ueno T, Ozawa K, Mano H.

Oncol Rep. 2013 Oct;30(4):1542-8. doi: 10.3892/or.2013.2605. Epub 2013 Jul 9.

PMID:
23842845
22.

Cancer-associated missense mutations of caspase-8 activate nuclear factor-κB signaling.

Ando M, Kawazu M, Ueno T, Fukumura K, Yamato A, Soda M, Yamashita Y, Choi YL, Yamasoba T, Mano H.

Cancer Sci. 2013 Aug;104(8):1002-8. doi: 10.1111/cas.12191. Epub 2013 Jun 7.

23.

Transforming mutations of RAC guanosine triphosphatases in human cancers.

Kawazu M, Ueno T, Kontani K, Ogita Y, Ando M, Fukumura K, Yamato A, Soda M, Takeuchi K, Miki Y, Yamaguchi H, Yasuda T, Naoe T, Yamashita Y, Katada T, Choi YL, Mano H.

Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):3029-34. doi: 10.1073/pnas.1216141110. Epub 2013 Feb 4.

24.

Multiple phosphorylation sites are important for RUNX1 activity in early hematopoiesis and T-cell differentiation.

Yoshimi M, Goyama S, Kawazu M, Nakagawa M, Ichikawa M, Imai Y, Kumano K, Asai T, Mulloy JC, Kraft AS, Takahashi T, Shirafuji N, Kurokawa M.

Eur J Immunol. 2012 Apr;42(4):1044-50. doi: 10.1002/eji.201040746.

25.

Oncogenic MAP2K1 mutations in human epithelial tumors.

Choi YL, Soda M, Ueno T, Hamada T, Haruta H, Yamato A, Fukumura K, Ando M, Kawazu M, Yamashita Y, Mano H.

Carcinogenesis. 2012 May;33(5):956-61. doi: 10.1093/carcin/bgs099. Epub 2012 Feb 10.

PMID:
22327936
26.

High-throughput resequencing of target-captured cDNA in cancer cells.

Ueno T, Yamashita Y, Soda M, Fukumura K, Ando M, Yamato A, Kawazu M, Choi YL, Mano H.

Cancer Sci. 2012 Jan;103(1):131-5. doi: 10.1111/j.1349-7006.2011.02105.x. Epub 2011 Oct 13.

27.

Histone demethylase JMJD2B functions as a co-factor of estrogen receptor in breast cancer proliferation and mammary gland development.

Kawazu M, Saso K, Tong KI, McQuire T, Goto K, Son DO, Wakeham A, Miyagishi M, Mak TW, Okada H.

PLoS One. 2011 Mar 18;6(3):e17830. doi: 10.1371/journal.pone.0017830.

28.

Evi-1 promotes para-aortic splanchnopleural hematopoiesis through up-regulation of GATA-2 and repression of TGF-b signaling.

Sato T, Goyama S, Nitta E, Takeshita M, Yoshimi M, Nakagawa M, Kawazu M, Ichikawa M, Kurokawa M.

Cancer Sci. 2008 Jul;99(7):1407-13. doi: 10.1111/j.1349-7006.2008.00842.x. Epub 2008 Apr 29.

29.

AML1/Runx1 negatively regulates quiescent hematopoietic stem cells in adult hematopoiesis.

Ichikawa M, Goyama S, Asai T, Kawazu M, Nakagawa M, Takeshita M, Chiba S, Ogawa S, Kurokawa M.

J Immunol. 2008 Apr 1;180(7):4402-8.

30.

Expression profiling of immature thymocytes revealed a novel homeobox gene that regulates double-negative thymocyte development.

Kawazu M, Yamamoto G, Yoshimi M, Yamamoto K, Asai T, Ichikawa M, Seo S, Nakagawa M, Chiba S, Kurokawa M, Ogawa S.

J Immunol. 2007 Oct 15;179(8):5335-45.

31.

AML1/Runx1 rescues Notch1-null mutation-induced deficiency of para-aortic splanchnopleural hematopoiesis.

Nakagawa M, Ichikawa M, Kumano K, Goyama S, Kawazu M, Asai T, Ogawa S, Kurokawa M, Chiba S.

Blood. 2006 Nov 15;108(10):3329-34. Epub 2006 Aug 3.

32.

Hematopoietic stem cells expanded by fibroblast growth factor-1 are excellent targets for retrovirus-mediated gene delivery.

Crcareva A, Saito T, Kunisato A, Kumano K, Suzuki T, Sakata-Yanagimoto M, Kawazu M, Stojanovic A, Kurokawa M, Ogawa S, Hirai H, Chiba S.

Exp Hematol. 2005 Dec;33(12):1459-69.

PMID:
16338488
33.

Crk-associated substrate lymphocyte type is required for lymphocyte trafficking and marginal zone B cell maintenance.

Seo S, Asai T, Saito T, Suzuki T, Morishita Y, Nakamoto T, Ichikawa M, Yamamoto G, Kawazu M, Yamagata T, Sakai R, Mitani K, Ogawa S, Kurokawa M, Chiba S, Hirai H.

J Immunol. 2005 Sep 15;175(6):3492-501.

34.

Functional domains of Runx1 are differentially required for CD4 repression, TCRbeta expression, and CD4/8 double-negative to CD4/8 double-positive transition in thymocyte development.

Kawazu M, Asai T, Ichikawa M, Yamamoto G, Saito T, Goyama S, Mitani K, Miyazono K, Chiba S, Ogawa S, Kurokawa M, Hirai H.

J Immunol. 2005 Mar 15;174(6):3526-33.

35.

Clinical significance of peripheral blood erythroblastosis after hematopoietic stem cell transplantation.

Goyama S, Kanda Y, Nannya Y, Ogawa S, Asano-Moki Y, Ogawa N, Nakagawa M, Sakata-Yanagimoto M, Kawazu M, Komeno Y, Imai Y, Hangaishi A, Kurokawa M, Tsujino S, Aoki K, Chiba S, Motokura T, Hirai H.

Leuk Lymphoma. 2004 Dec;45(12):2439-43.

PMID:
15621756
36.

The transcriptionally active form of AML1 is required for hematopoietic rescue of the AML1-deficient embryonic para-aortic splanchnopleural (P-Sp) region.

Goyama S, Yamaguchi Y, Imai Y, Kawazu M, Nakagawa M, Asai T, Kumano K, Mitani K, Ogawa S, Chiba S, Kurokawa M, Hirai H.

Blood. 2004 Dec 1;104(12):3558-64. Epub 2004 Jul 22.

38.

Male predominance among Japanese adult patients with late-onset hemorrhagic cystitis after hematopoietic stem cell transplantation.

Asano Y, Kanda Y, Ogawa N, Sakata-Yanagimoto M, Nakagawa M, Kawazu M, Goyama S, Kandabashi K, Izutsu K, Imai Y, Hangaishi A, Kurokawa M, Tsujino S, Ogawa S, Aoki K, Chiba S, Motokura T, Hirai H.

Bone Marrow Transplant. 2003 Dec;32(12):1175-9. Review.

PMID:
14647272
39.

Reduced-intensity bone marrow transplantation from an alternative unrelated donor for myelodysplastic syndrome of first-donor origin.

Komeno Y, Kanda Y, Kandabashi K, Kawazu M, Goyama S, Takeshita M, Nannya Y, Niino M, Nakamoto T, Kurokawa M, Tsujino S, Ogawa S, Aoki K, Chiba S, Motokura T, Hirai H.

Am J Hematol. 2003 Mar;72(3):220-2.

40.

Reverse seroconversion of hepatitis B virus after hematopoietic stem cell transplantation.

Goyama S, Kanda Y, Nannya Y, Kawazu M, Takeshita M, Niino M, Komeno Y, Nakamoto T, Kurokawa M, Tsujino S, Ogawa S, Aoki K, Chiba S, Motokura T, Shiratori Y, Hirai H.

Leuk Lymphoma. 2002 Nov;43(11):2159-63. Review.

PMID:
12533042
41.

Rapid diagnosis of invasive pulmonary aspergillosis by quantitative polymerase chain reaction using bronchial lavage fluid.

Kawazu M, Kanda Y, Goyama S, Takeshita M, Nannya Y, Niino M, Komeno Y, Nakamoto T, Kurokawa M, Tsujino S, Ogawa S, Aoki K, Chiba S, Motokura T, Ohishi N, Hirai H.

Am J Hematol. 2003 Jan;72(1):27-30.

42.

Contribution of working memory to transient activation in human inferior prefrontal cortex during performance of the Wisconsin Card Sorting Test.

Konishi S, Kawazu M, Uchida I, Kikyo H, Asakura I, Miyashita Y.

Cereb Cortex. 1999 Oct-Nov;9(7):745-53.

PMID:
10554997
43.

Imaging device using a roof mirror lens array.

Kawazu M, Inokuchi T.

Appl Opt. 1985 Dec 15;24(24):4300. No abstract available.

PMID:
18224201
44.

Synthesis and antibacterial activity of asparagine derivatives of aminobenzylpenicillin.

Wagatsuma M, Seto M, Miyagishima T, Kawazu M, Yamaguchi T, Ohshima S.

J Antibiot (Tokyo). 1983 Feb;36(2):147-54.

45.

Application of gradient-index fiber arrays to copying machines.

Kawazu M, Ogura Y.

Appl Opt. 1980 Apr 1;19(7):1105-12. doi: 10.1364/AO.19.001105.

PMID:
20220994
46.

Studies on the oxidation of "reversed nucleosides" in oxygen. II. Synthesis of homoeritadenine and threo-eritadenine.

Takamura N, Taga N, Kanno T, Kawazu M.

J Org Chem. 1973 Aug 10;38(16):2891-5. No abstract available.

PMID:
4733446
47.

Studies on the oxidation of "reversed nucleosides" in oxygen. I. Synthesis of eritadenine and its derivatives.

Kawazu M, Kanno T, Yamamura S, Mizoguchi T, Saito S.

J Org Chem. 1973 Aug 10;38(16):2887-90. No abstract available.

PMID:
4733445
48.
49.

5-hydroxy-3-piperidylidenemethane derivatives as spasmolytics.

Kawazu M, Kanno T, Saito S, Tamaki H.

J Med Chem. 1972 Sep;15(9):914-8. No abstract available.

PMID:
5051008
50.

[Studies on the chemotherapy of cancer by regional perfusion, with special reference to blood level of chemotherapeutic agent].

Kawazu M.

Kumamoto Igakkai Zasshi. 1971 Mar 25;45(3):391-413. Japanese. No abstract available.

PMID:
5109291

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