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Items: 1 to 50 of 65

1.

The weak voltage dependence of pannexin 1 channels can be tuned by N-terminal modifications.

Michalski K, Henze E, Nguyen P, Lynch P, Kawate T.

J Gen Physiol. 2018 Dec 3;150(12):1758-1768. doi: 10.1085/jgp.201711804. Epub 2018 Oct 30.

PMID:
30377218
2.

Expression of DJ-1 in Cancer Cells: Its Correlation with Clinical Significance.

Kawate T, Tsuchiya B, Iwaya K.

Adv Exp Med Biol. 2017;1037:45-59. doi: 10.1007/978-981-10-6583-5_4. Review.

PMID:
29147902
3.

Expression and Purification of a Mammalian P2X7 Receptor from Sf9 Insect Cells.

Karasawa A, Kawate T.

Bio Protoc. 2017 Sep 5;7(17). pii: e2544. doi: 10.21769/BioProtoc.2544.

4.

The P2X7 receptor forms a dye-permeable pore independent of its intracellular domain but dependent on membrane lipid composition.

Karasawa A, Michalski K, Mikhelzon P, Kawate T.

Elife. 2017 Sep 18;6. pii: e31186. doi: 10.7554/eLife.31186.

5.

P2X Receptor Activation.

Kawate T.

Adv Exp Med Biol. 2017;1051:55-69. doi: 10.1007/5584_2017_55. Review.

PMID:
28639248
6.

Structural basis for subtype-specific inhibition of the P2X7 receptor.

Karasawa A, Kawate T.

Elife. 2016 Dec 9;5. pii: e22153. doi: 10.7554/eLife.22153.

7.

Baeyer-Villiger Monooxygenases EthA and MymA Are Required for Activation of Replicating and Non-replicating Mycobacterium tuberculosis Inhibitors.

Grant SS, Wellington S, Kawate T, Desjardins CA, Silvis MR, Wivagg C, Thompson M, Gordon K, Kazyanskaya E, Nietupski R, Haseley N, Iwase N, Earl AM, Fitzgerald M, Hung DT.

Cell Chem Biol. 2016 Jun 23;23(6):666-77. doi: 10.1016/j.chembiol.2016.05.011. Epub 2016 Jun 16.

8.

Membrane Protein Mobility and Orientation Preserved in Supported Bilayers Created Directly from Cell Plasma Membrane Blebs.

Richards MJ, Hsia CY, Singh RR, Haider H, Kumpf J, Kawate T, Daniel S.

Langmuir. 2016 Mar 29;32(12):2963-74. doi: 10.1021/acs.langmuir.5b03415. Epub 2016 Feb 17.

PMID:
26812542
9.

Carbenoxolone inhibits Pannexin1 channels through interactions in the first extracellular loop.

Michalski K, Kawate T.

J Gen Physiol. 2016 Feb;147(2):165-74. doi: 10.1085/jgp.201511505. Epub 2016 Jan 11.

10.

High levels of DJ-1 protein and isoelectric point 6.3 isoform in sera of breast cancer patients.

Kawate T, Iwaya K, Koshikawa K, Moriya T, Yamasaki T, Hasegawa S, Kaise H, Fujita T, Matsuo H, Nakamura T, Ishikawa T, Hiroi S, Iguchi-Ariga SM, Ariga H, Murota K, Fujimori M, Yamamoto J, Matsubara O, Kohno N.

Cancer Sci. 2015 Jul;106(7):938-43. doi: 10.1111/cas.12673. Epub 2015 May 6.

11.

Identification of a chemically validated target in replicating and non-replicating Mycobacterium tuberculosis with the aid of a small molecule probe.

Nag PP, Grant SS, Lewis TA, Gordon K, Kawate T, Fitzgerald M, Nietupski R, Gomez J, White EL, Maddox C, Nebane NM, Tower NA, McKellip S, Sosa M, Rasmussen L, Johnston S, Bittker JA, Dandapani S, Perez J, Munoz B, Palmer M, Schreiber SL, Hung DT.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2014 Apr 15 [updated 2015 Jan 16].

12.

Elucidation of the physiology of non-replicating, drug tolerant Mycobacterium tuberculosis with the aid of the small molecule probe ML338.

Nag PP, Grant SS, Lewis TA, Gordon K, Kawate T, Iwase N, White EL, Maddox C, Nebane NM, Tower NA, McKellip S, Sosa MI, Rasmussen L, Mosher CM, Anthoine T, Johnston S, Dandapani S, Perez J, Munoz B, Palmer M, Schreiber SL, Hung DT.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2012 Dec 17 [updated 2013 Sep 16].

13.

Accuracy and validity of sentinel lymph node biopsy for breast cancer using a photosensitizer: 8-year follow-up.

Yamada K, Ogata A, Kaise H, Oda M, Kimura F, Komatsu S, Nakamura Y, Hosonaga M, Matsumura M, Kawate T, Miyahara K, Kawai Y, Ueda A, Teraoka S, Kohno N.

Lasers Surg Med. 2013 Nov;45(9):558-63. doi: 10.1002/lsm.22183. Epub 2013 Sep 30.

PMID:
24114757
14.

Synthesis and structure-activity relationships of phenyl-substituted coumarins with anti-tubercular activity that target FadD32.

Kawate T, Iwase N, Shimizu M, Stanley SA, Wellington S, Kazyanskaya E, Hung DT.

Bioorg Med Chem Lett. 2013 Nov 15;23(22):6052-9. doi: 10.1016/j.bmcl.2013.09.035. Epub 2013 Sep 19.

PMID:
24103299
15.

Identification of novel inhibitors of nonreplicating Mycobacterium tuberculosis using a carbon starvation model.

Grant SS, Kawate T, Nag PP, Silvis MR, Gordon K, Stanley SA, Kazyanskaya E, Nietupski R, Golas A, Fitzgerald M, Cho S, Franzblau SG, Hung DT.

ACS Chem Biol. 2013 Oct 18;8(10):2224-34. doi: 10.1021/cb4004817. Epub 2013 Aug 13.

16.

Diarylcoumarins inhibit mycolic acid biosynthesis and kill Mycobacterium tuberculosis by targeting FadD32.

Stanley SA, Kawate T, Iwase N, Shimizu M, Clatworthy AE, Kazyanskaya E, Sacchettini JC, Ioerger TR, Siddiqi NA, Minami S, Aquadro JA, Grant SS, Rubin EJ, Hung DT.

Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):11565-70. doi: 10.1073/pnas.1302114110. Epub 2013 Jun 24.

17.

Chemical genetics reveals a kinase-independent role for protein kinase R in pyroptosis.

Hett EC, Slater LH, Mark KG, Kawate T, Monks BG, Stutz A, Latz E, Hung DT.

Nat Chem Biol. 2013 Jun;9(6):398-405. doi: 10.1038/nchembio.1236. Epub 2013 Apr 21. Erratum in: Nat Chem Biol. 2013 Jul;9(7):466.

PMID:
23603659
18.

DJ-1 protein expression as a predictor of pathological complete remission after neoadjuvant chemotherapy in breast cancer patients.

Kawate T, Iwaya K, Kikuchi R, Kaise H, Oda M, Sato E, Hiroi S, Matsubara O, Kohno N.

Breast Cancer Res Treat. 2013 May;139(1):51-9. doi: 10.1007/s10549-013-2523-0. Epub 2013 Apr 17.

PMID:
23592371
19.

Identification of novel inhibitors of M. tuberculosis growth using whole cell based high-throughput screening.

Stanley SA, Grant SS, Kawate T, Iwase N, Shimizu M, Wivagg C, Silvis M, Kazyanskaya E, Aquadro J, Golas A, Fitzgerald M, Dai H, Zhang L, Hung DT.

ACS Chem Biol. 2012 Aug 17;7(8):1377-84. doi: 10.1021/cb300151m. Epub 2012 May 21.

20.

Clinical significance of DJ-1 as a secretory molecule: retrospective study of DJ-1 expression at mRNA and protein levels in ductal carcinoma of the breast.

Tsuchiya B, Iwaya K, Kohno N, Kawate T, Akahoshi T, Matsubara O, Mukai K.

Histopathology. 2012 Jul;61(1):69-77. doi: 10.1111/j.1365-2559.2012.04202.x. Epub 2012 Mar 2.

PMID:
22385318
21.

STAT6 phosphorylation inhibitors block eotaxin-3 secretion in bronchial epithelial cells.

Zhou L, Kawate T, Liu X, Kim YB, Zhao Y, Feng G, Banerji J, Nash H, Whitehurst C, Jindal S, Siddiqui A, Seed B, Wolfe JL.

Bioorg Med Chem. 2012 Jan 15;20(2):750-8. doi: 10.1016/j.bmc.2011.12.006. Epub 2011 Dec 17.

22.

Ion access pathway to the transmembrane pore in P2X receptor channels.

Kawate T, Robertson JL, Li M, Silberberg SD, Swartz KJ.

J Gen Physiol. 2011 Jun;137(6):579-90. doi: 10.1085/jgp.201010593.

23.

Signaling through the primary cilium affects glial cell survival under a stressed environment.

Yoshimura K, Kawate T, Takeda S.

Glia. 2011 Feb;59(2):333-44. doi: 10.1002/glia.21105.

PMID:
21125655
24.

Pore-opening mechanism in trimeric P2X receptor channels.

Li M, Kawate T, Silberberg SD, Swartz KJ.

Nat Commun. 2010 Jul 27;1:44. doi: 10.1038/ncomms1048.

25.

Multiple primary cilia modulate the fluid transcytosis in choroid plexus epithelium.

Narita K, Kawate T, Kakinuma N, Takeda S.

Traffic. 2010 Feb;11(2):287-301. doi: 10.1111/j.1600-0854.2009.01016.x. Epub 2009 Nov 17.

27.

Pore architecture and ion sites in acid-sensing ion channels and P2X receptors.

Gonzales EB, Kawate T, Gouaux E.

Nature. 2009 Jul 30;460(7255):599-604. doi: 10.1038/nature08218.

28.

Crystal structure of the ATP-gated P2X(4) ion channel in the closed state.

Kawate T, Michel JC, Birdsong WT, Gouaux E.

Nature. 2009 Jul 30;460(7255):592-8. doi: 10.1038/nature08198.

29.

Histochemical analysis of renal dysplasia with ureteral atresia.

Kawate T, Kawamura R, Uchida T, Takahashi K, Hasegawa T, Futamata H, Katoh R, Takeda S.

Acta Histochem Cytochem. 2009 Jun 27;42(3):65-71. doi: 10.1267/ahc.09009. Epub 2009 Apr 25.

30.
31.

Large-caliber persistent sciatic artery with aneurysm.

Futamata H, Kawate T, Sakamoto H, Kitami Y, Takeda S.

Anat Sci Int. 2008 Dec;83(4):301-6. doi: 10.1111/j.1447-073X.2008.00228.x. Review.

PMID:
19159365
32.

Rare multiple combined anomaly of the vertebral vessels and bronchial artery.

Kawate T, Futamata H, Kitami Y, Takeda S.

Anat Sci Int. 2008 Dec;83(4):267-72. doi: 10.1111/j.1447-073X.2007.00197.x.

PMID:
19159356
33.

Synthesis and polymerase incorporation of 5'-amino-2',5'-dideoxy-5'-N-triphosphate nucleotides.

Wolfe JL, Kawate T.

Curr Protoc Nucleic Acid Chem. 2004 Oct;Chapter 13:Unit 13.3. doi: 10.1002/0471142700.nc1303s18. Review.

PMID:
18428923
34.

Chromospheric anemone jets as evidence of ubiquitous reconnection.

Shibata K, Nakamura T, Matsumoto T, Otsuji K, Okamoto TJ, Nishizuka N, Kawate T, Watanabe H, Nagata S, Ueno S, Kitai R, Nozawa S, Tsuneta S, Suematsu Y, Ichimoto K, Shimizu T, Katsukawa Y, Tarbell TD, Berger TE, Lites BW, Shine RA, Title AM.

Science. 2007 Dec 7;318(5856):1591-4.

35.
36.

Cyclo-oxygenase-2-immunoreactive neurons in the lumbar dorsal horn in a chicken acute inflammation model.

Yamada S, Kawate T, Sakamoto H, Aoki K, Hamada Y, Atsumi S.

Anat Sci Int. 2006 Sep;81(3):164-72.

PMID:
16955667
38.

Immunohistochemical study of delta and mu opioid receptors on synaptic glomeruli with substance P-positive central terminals in chicken dorsal horn.

Kawate T, Sakamoto H, Yang C, Li Y, Shimada O, Atsumi S.

Neurosci Res. 2005 Nov;53(3):279-87. Epub 2005 Sep 13.

PMID:
16165241
39.

Subsurface cisterna-lined axonal invaginations and double-walled vesicles at the axonal-myelin sheath interface.

Li YC, Li YN, Cheng CX, Sakamoto H, Kawate T, Shimada O, Atsumi S.

Neurosci Res. 2005 Nov;53(3):298-303. Epub 2005 Aug 29.

PMID:
16129504
40.
41.

Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters.

Yamashita A, Singh SK, Kawate T, Jin Y, Gouaux E.

Nature. 2005 Sep 8;437(7056):215-23. Epub 2005 Jul 24.

PMID:
16041361
43.

Organization of a sterol-rich membrane domain by cdc15p during cytokinesis in fission yeast.

Takeda T, Kawate T, Chang F.

Nat Cell Biol. 2004 Nov;6(11):1142-4. Epub 2004 Nov 1.

PMID:
15517003
44.

Protein-trap version 2.1: screening for expressed proteins in mammalian cells based on their localizations.

Sineshchekova OO, Kawate T, Vdovychenko OV, Sato TN.

BMC Cell Biol. 2004 Feb 2;5:8.

45.

Sequence-specific dinucleotide cleavage promoted by synergistic interactions between neighboring modified nucleotides in DNA.

Wolfe JL, Wang BH, Kawate T, Stanton VP Jr.

J Am Chem Soc. 2003 Sep 3;125(35):10500-1.

PMID:
12940715
47.

Synthesis and polymerase incorporation of 5'-amino-2',5'-dideoxy-5'-N-triphosphate nucleotides.

Wolfe JL, Kawate T, Belenky A, Stanton V Jr.

Nucleic Acids Res. 2002 Sep 1;30(17):3739-47.

48.

A genotyping strategy based on incorporation and cleavage of chemically modified nucleotides.

Wolfe JL, Kawate T, Sarracino DA, Zillmann M, Olson J, Stanton VP Jr, Verdine GL.

Proc Natl Acad Sci U S A. 2002 Aug 20;99(17):11073-8. Epub 2002 Aug 8.

49.

Asymmetric Addition of Alkyllithium to Chiral Imines: alpha-Naphthylethyl Group as a Chiral Auxiliary.

Yamada H, Kawate T, Nishida A, Nakagawa M.

J Org Chem. 1999 Nov 26;64(24):8821-8828.

PMID:
11674785
50.

Chiral Lewis Acid-Mediated Enantioselective Pictet-Spengler Reaction of N(b)-Hydroxytryptamine with Aldehydes.

Yamada H, Kawate T, Matsumizu M, Nishida A, Yamaguchi K, Nakagawa M.

J Org Chem. 1998 Sep 4;63(18):6348-6354.

PMID:
11672269

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