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Items: 1 to 50 of 141

1.

A prospective compound screening contest identified broader inhibitors for Sirtuin 1.

Chiba S, Ohue M, Gryniukova A, Borysko P, Zozulya S, Yasuo N, Yoshino R, Ikeda K, Shin WH, Kihara D, Iwadate M, Umeyama H, Ichikawa T, Teramoto R, Hsin KY, Gupta V, Kitano H, Sakamoto M, Higuchi A, Miura N, Yura K, Mochizuki M, Ramakrishnan C, Thangakani AM, Velmurugan D, Gromiha MM, Nakane I, Uchida N, Hakariya H, Tan M, Nakamura HK, Suzuki SD, Ito T, Kawatani M, Kudoh K, Takashina S, Yamamoto KZ, Moriwaki Y, Oda K, Kobayashi D, Okuno T, Minami S, Chikenji G, Prathipati P, Nagao C, Mohsen A, Ito M, Mizuguchi K, Honma T, Ishida T, Hirokawa T, Akiyama Y, Sekijima M.

Sci Rep. 2019 Dec 20;9(1):19585. doi: 10.1038/s41598-019-55069-y.

2.

Identification of a Small Compound Targeting PKM2-Regulated Signaling Using 2D Gel Electrophoresis-Based Proteome-wide CETSA.

Nagasawa I, Muroi M, Kawatani M, Ohishi T, Ohba SI, Kawada M, Osada H.

Cell Chem Biol. 2020 Feb 20;27(2):186-196.e4. doi: 10.1016/j.chembiol.2019.11.010. Epub 2019 Dec 5.

PMID:
31813846
3.

Micro-CT imaging analysis for the effects of ibandronate and eldecalcitol on secondary osteoporosis and arthritis in adjuvant-induced arthritis rats.

Ono Y, Miyakoshi N, Kasukawa Y, Imai Y, Nagasawa H, Tsuchie H, Akagawa M, Nagahata I, Yuasa Y, Sato C, Kawatani M, Shimada Y.

Biomed Res. 2019;40(5):197-205. doi: 10.2220/biomedres.40.197.

4.

Structure and biological activity of Metarhizin C, a stereoisomer of BR-050 from Tolypocladium album RK17-F0007.

Nogawa T, Kawatani M, Okano A, Futamura Y, Aono H, Shimizu T, Kato N, Kikuchi H, Osada H.

J Antibiot (Tokyo). 2019 Dec;72(12):996-1000. doi: 10.1038/s41429-019-0229-1. Epub 2019 Sep 3.

PMID:
31481762
5.

Peripheral nerve injury in rats induces alternations in choice behavior associated with food reinforcement.

Hayashida KI, Eisenach JC, Kawatani M, Martin TJ.

J Physiol Sci. 2019 Sep;69(5):769-777. doi: 10.1007/s12576-019-00693-6. Epub 2019 Jul 2.

PMID:
31267368
6.

Fluorescence Detection of Prostate Cancer by an Activatable Fluorescence Probe for PSMA Carboxypeptidase Activity.

Kawatani M, Yamamoto K, Yamada D, Kamiya M, Miyakawa J, Miyama Y, Kojima R, Morikawa T, Kume H, Urano Y.

J Am Chem Soc. 2019 Jul 3;141(26):10409-10416. doi: 10.1021/jacs.9b04412. Epub 2019 Jun 21.

PMID:
31244179
7.

A case of early myoclonic encephalopathy with intractable seizures successfully treated with high-dose phenobarbital.

Kosaka T, Ohta G, Kometani H, Kawatani M, Ohshima Y.

Brain Dev. 2019 Sep;41(8):717-720. doi: 10.1016/j.braindev.2019.04.007. Epub 2019 Apr 23.

PMID:
31027651
8.

Novel agonist of α4β2* neuronal nicotinic receptor with antinociceptive efficacy in rodent models of acute and chronic pain.

Sudo RT, Hayashida K, Santos AN, Kawatani M, Monteiro CE, Moreira RD, Trachez MM, Montes GC, Zapata-Sudo G.

J Pain Res. 2018 Oct 30;11:2453-2462. doi: 10.2147/JPR.S169637. eCollection 2018.

9.

Glucagon-like peptide-1 (GLP-1) action in the mouse area postrema neurons.

Kawatani M, Yamada Y, Kawatani M.

Peptides. 2018 Sep;107:68-74. doi: 10.1016/j.peptides.2018.07.010. Epub 2018 Aug 3.

PMID:
30081042
10.

Bioenergetic and proteomic profiling to screen small molecule inhibitors that target cancer metabolisms.

Futamura Y, Muroi M, Aono H, Kawatani M, Hayashida M, Sekine T, Nogawa T, Osada H.

Biochim Biophys Acta Proteins Proteom. 2019 Jan;1867(1):28-37. doi: 10.1016/j.bbapap.2018.06.001. Epub 2018 Jun 6.

PMID:
29883687
11.

Factors affecting the uncaging efficiency of 500 nm light-activatable BODIPY caging group.

Kawatani M, Kamiya M, Takahashi H, Urano Y.

Bioorg Med Chem Lett. 2018 Jan 1;28(1):1-5. doi: 10.1016/j.bmcl.2017.11.030. Epub 2017 Nov 16.

PMID:
29239736
12.

Noradrenergic effects in rat sacral autonomic nucleus using in vitro slice patch-clamp recordings.

Kawatani M, Akimoto N, Yamada A, Furue H, Kawatani M.

Biomed Res. 2017;38(6):359-369. doi: 10.2220/biomedres.38.359.

13.

Actin-binding protein coronin 1A controls osteoclastic bone resorption by regulating lysosomal secretion of cathepsin K.

Ohmae S, Noma N, Toyomoto M, Shinohara M, Takeiri M, Fuji H, Takemoto K, Iwaisako K, Fujita T, Takeda N, Kawatani M, Aoyama M, Hagiwara M, Ishihama Y, Asagiri M.

Sci Rep. 2017 Mar 16;7:41710. doi: 10.1038/srep41710.

14.

Proteomic profiling reveals that collismycin A is an iron chelator.

Kawatani M, Muroi M, Wada A, Inoue G, Futamura Y, Aono H, Shimizu K, Shimizu T, Igarashi Y, Takahashi-Ando N, Osada H.

Sci Rep. 2016 Dec 6;6:38385. doi: 10.1038/srep38385.

15.

Decision making processes based on social conventional rules in early adolescents with and without autism spectrum disorders.

Komeda H, Osanai H, Yanaoka K, Okamoto Y, Fujioka T, Arai S, Inohara K, Koyasu M, Kusumi T, Takiguchi S, Kawatani M, Kumazaki H, Hiratani M, Tomoda A, Kosaka H.

Sci Rep. 2016 Nov 29;6:37875. doi: 10.1038/srep37875.

16.

Identification and structure-activity relationship of purine derivatives as novel MTH1 inhibitors.

Kumar A, Kawamura T, Kawatani M, Osada H, Zhang KYJ.

Chem Biol Drug Des. 2017 Jun;89(6):862-869. doi: 10.1111/cbdd.12909. Epub 2016 Dec 7.

PMID:
27863017
17.

ATP release from bladder urothelium and serosa in a rat model of partial bladder outlet obstruction.

Shiina K, Hayashida KI, Ishikawa K, Kawatani M.

Biomed Res. 2016;37(5):299-304.

18.

Proteomic profiling of small-molecule inhibitors reveals dispensability of MTH1 for cancer cell survival.

Kawamura T, Kawatani M, Muroi M, Kondoh Y, Futamura Y, Aono H, Tanaka M, Honda K, Osada H.

Sci Rep. 2016 May 23;6:26521. doi: 10.1038/srep26521.

19.

Identification of a novel compound that inhibits osteoclastogenesis by suppressing nucleoside transporters.

Katsuyama S, Sugino K, Sasazawa Y, Nakano Y, Aono H, Morishita K, Kawatani M, Umezawa K, Osada H, Simizu S.

FEBS Lett. 2016 Apr;590(8):1152-62. doi: 10.1002/1873-3468.12146. Epub 2016 Apr 3.

20.

Unantimycin A, a new neoantimycin analog isolated from a microbial metabolite fraction library.

Lim CL, Nogawa T, Okano A, Futamura Y, Kawatani M, Takahashi S, Ibrahim D, Osada H.

J Antibiot (Tokyo). 2016 Jun;69(6):456-8. doi: 10.1038/ja.2015.124. Epub 2015 Dec 9. No abstract available.

PMID:
26648115
21.

Serotonergic regulation of distention-induced ATP release from the urothelium.

Matsumoto-Miyai K, Yamada E, Shinzawa E, Koyama Y, Shimada S, Yoshizumi M, Kawatani M.

Am J Physiol Renal Physiol. 2016 Apr 1;310(7):F646-F655. doi: 10.1152/ajprenal.00024.2015. Epub 2015 Nov 18.

22.

Reveromycin A Administration Prevents Alveolar Bone Loss in Osteoprotegerin Knockout Mice with Periodontal Disease.

Mizuno M, Miyazawa K, Tabuchi M, Tanaka M, Yoshizako M, Minamoto C, Torii Y, Tamaoka Y, Kawatani M, Osada H, Maeda H, Goto S.

Sci Rep. 2015 Nov 12;5:16510. doi: 10.1038/srep16510.

23.

Regulatory Effects of 5-Hydroxytryptamine Receptors on Voiding Function.

Matsumoto-Miyai K, Yoshizumi M, Kawatani M.

Adv Ther. 2015 Oct;32 Suppl 1:3-15. doi: 10.1007/s12325-015-0240-2. Epub 2015 Sep 21. Review.

PMID:
26391372
24.

[Chemical biology and novel molecular-targeted agents in cancer therapy].

Kawatani M, Osada H.

Nihon Rinsho. 2015 Aug;73(8):1273-80. Review. Japanese.

PMID:
26281678
25.

An overproduction of astellolides induced by genetic disruption of chromatin-remodeling factors in Aspergillus oryzae.

Shinohara Y, Kawatani M, Futamura Y, Osada H, Koyama Y.

J Antibiot (Tokyo). 2016 Jan;69(1):4-8. doi: 10.1038/ja.2015.73. Epub 2015 Jul 1.

PMID:
26126743
26.

Neuritogenic Activity of Tetradecyl 2,3-Dihydroxybenzoate Is Mediated through the Insulin-Like Growth Factor 1 Receptor/Phosphatidylinositol 3 Kinase/Mitogen-Activated Protein Kinase Signaling Pathway.

Tang R, Gao L, Kawatani M, Chen J, Cao X, Osada H, Xiang L, Qi J.

Mol Pharmacol. 2015 Aug;88(2):326-34. doi: 10.1124/mol.115.097758. Epub 2015 May 26.

PMID:
26013540
27.

Identification of matrix metalloproteinase inhibitors by chemical arrays.

Kawatani M, Fukushima Y, Kondoh Y, Honda K, Sekine T, Yamaguchi Y, Taniguchi N, Osada H.

Biosci Biotechnol Biochem. 2015;79(10):1597-602. doi: 10.1080/09168451.2015.1045829. Epub 2015 May 19.

PMID:
25988721
28.

Methyl 3-((6-methoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-yl)amino)benzoate (GN39482) as a tubulin polymerization inhibitor identified by MorphoBase and ChemProteoBase profiling methods.

Minegishi H, Futamura Y, Fukashiro S, Muroi M, Kawatani M, Osada H, Nakamura H.

J Med Chem. 2015 May 28;58(10):4230-41. doi: 10.1021/acs.jmedchem.5b00035. Epub 2015 May 11.

PMID:
25938266
29.

Structure-function analyses of cytochrome P450revI involved in reveromycin A biosynthesis and evaluation of the biological activity of its substrate, reveromycin T.

Takahashi S, Nagano S, Nogawa T, Kanoh N, Uramoto M, Kawatani M, Shimizu T, Miyazawa T, Shiro Y, Osada H.

J Biol Chem. 2014 Nov 21;289(47):32446-58. doi: 10.1074/jbc.M114.598391. Epub 2014 Sep 25.

30.

[Assessment of brain perfusion by arterial spin-labeling MR imaging in qusai-moyamoya disease associated with Graves' disease].

Hayashi H, Kawatani M, Ohta G, Kometani H, Ohshima Y.

No To Hattatsu. 2014 Jul;46(4):297-300. Japanese.

PMID:
25154228
31.

A small molecule that induces reactive oxygen species via cellular glutathione depletion.

Kawamura T, Kondoh Y, Muroi M, Kawatani M, Osada H.

Biochem J. 2014 Oct 1;463(1):53-63. doi: 10.1042/BJ20140669.

PMID:
25011393
32.

Characterizing substrate properties of purine-related compounds with purine metabolism enzymes for enzymatic peak-shift HPLC method.

Fukuuchi T, Morimura A, Kawatani M, Yamamoto K, Yamaoka N, Kaneko K.

Nucleosides Nucleotides Nucleic Acids. 2014;33(4-6):445-53. doi: 10.1080/15257770.2013.863333.

PMID:
24940703
33.

Synergistic effects of loxoprofen and glycine on the micturition reflex in conscious rats.

Fukiya Y, Yoshizumi M, Saito M, Matsumoto-Miyai K, Nimura T, Kawatani M.

Biomed Res. 2014;35(1):17-23.

34.

Quetiapine responsive catatonia in an autistic patient with comorbid bipolar disorder and idiopathic basal ganglia calcification.

Ishitobi M, Kawatani M, Asano M, Kosaka H, Goto T, Hiratani M, Wada Y.

Brain Dev. 2014 Oct;36(9):823-5. doi: 10.1016/j.braindev.2013.12.005. Epub 2014 Jan 13.

PMID:
24434185
35.

[A male case of subcortical band heterotopia with somatic mosaicism of DCX mutation].

Igarashi A, Kawatani M, Ohta G, Kometani H, Ohshima Y, Kato M.

No To Hattatsu. 2013 Sep;45(5):371-4. Japanese.

PMID:
24205692
36.

Identification of a molecular target of a novel fungal metabolite, pyrrolizilactone, by phenotypic profiling systems.

Futamura Y, Kawatani M, Muroi M, Aono H, Nogawa T, Osada H.

Chembiochem. 2013 Dec 16;14(18):2456-63. doi: 10.1002/cbic.201300499. Epub 2013 Oct 25.

PMID:
24166831
37.

Stabilization of tooth movement by administration of reveromycin A to osteoprotegerin-deficient knockout mice.

Yabumoto T, Miyazawa K, Tabuchi M, Shoji S, Tanaka M, Kadota M, Yoshizako M, Kawatani M, Osada H, Maeda H, Goto S.

Am J Orthod Dentofacial Orthop. 2013 Sep;144(3):368-80. doi: 10.1016/j.ajodo.2013.04.016.

PMID:
23992809
38.

Marked elevation of interleukin-6 in mild encephalopathy with a reversible splenial lesion (MERS) associated with acute focal bacterial nephritis caused by Enterococcus faecalis.

Kometani H, Kawatani M, Ohta G, Okazaki S, Ogura K, Yasutomi M, Tanizawa A, Ohshima Y.

Brain Dev. 2014 Jun;36(6):551-3. doi: 10.1016/j.braindev.2013.07.012. Epub 2013 Aug 24.

PMID:
23978488
39.

Pyrrolizilactone, a new pyrrolizidinone metabolite produced by a fungus.

Nogawa T, Kawatani M, Uramoto M, Okano A, Aono H, Futamura Y, Koshino H, Takahashi S, Osada H.

J Antibiot (Tokyo). 2013 Oct;66(10):621-3. doi: 10.1038/ja.2013.55. Epub 2013 May 29. No abstract available.

PMID:
23715039
40.

Isolation of new polyketide metabolites, linearolides A and B, from Streptomyces sp. RK95-74.

Ueki M, Koshiro N, Aono H, Kawatani M, Uramoto M, Kawasaki H, Osada H.

J Antibiot (Tokyo). 2013 Jun;66(6):333-7. doi: 10.1038/ja.2013.19. Epub 2013 Mar 27.

41.

[Cytoskeletal system].

Kawatani M, Osada H.

Nihon Rinsho. 2012 Nov;70 Suppl 8:130-4. Japanese. No abstract available.

PMID:
23513825
42.

Dual structure-activity relationship of osteoclastogenesis inhibitor methyl gerfelin based on TEG scanning.

Kanoh N, Suzuki T, Kawatani M, Katou Y, Osada H, Iwabuchi Y.

Bioconjug Chem. 2013 Jan 16;24(1):44-52. doi: 10.1021/bc3003666. Epub 2013 Jan 7.

PMID:
23270365
43.

Morphobase, an encyclopedic cell morphology database, and its use for drug target identification.

Futamura Y, Kawatani M, Kazami S, Tanaka K, Muroi M, Shimizu T, Tomita K, Watanabe N, Osada H.

Chem Biol. 2012 Dec 21;19(12):1620-30. doi: 10.1016/j.chembiol.2012.10.014.

44.

Creation of novel reveromycin derivatives by alcohol-added fermentation.

Nogawa T, Takahashi S, Sekiyama Y, Takagi H, Uramoto M, Koshino H, Kawatani M, Shimizu T, Osada H.

J Antibiot (Tokyo). 2013 Apr;66(4):247-50. doi: 10.1038/ja.2012.115. Epub 2012 Dec 12. No abstract available.

PMID:
23232929
45.

Violaceols function as actin inhibitors inducing cell shape elongation in fibroblast cells.

Asami Y, Jang JH, Oh H, Sohn JH, Kim JW, Moon DO, Kwon O, Kawatani M, Osada H, Kim BY, Ahn JS.

Biosci Biotechnol Biochem. 2012;76(8):1431-7. Epub 2012 Aug 7.

46.

The regulation of distention-induced ATP release from urothelium by the adenylyl cyclase-cyclic AMP pathway.

Matsumoto-Miyai K, Yamada E, Yoshizumi M, Kawatani M.

Biomed Res. 2012 Jun;33(3):153-7.

47.

Effect of Reveromycin A on experimental tooth movement in OPG-/- mice.

Tanaka M, Miyazawa K, Tabuchi M, Yabumoto T, Kadota M, Yoshizako M, Yamane C, Kawatani M, Osada H, Maeda H, Goto S.

J Dent Res. 2012 Aug;91(8):771-6. doi: 10.1177/0022034512451026. Epub 2012 Jun 6.

PMID:
22674934
48.

Protein disulfide isomerase-mediated disulfide bonds regulate the gelatinolytic activity and secretion of matrix metalloproteinase-9.

Khan MM, Simizu S, Suzuki T, Masuda A, Kawatani M, Muroi M, Dohmae N, Osada H.

Exp Cell Res. 2012 May 1;318(8):904-14. doi: 10.1016/j.yexcr.2012.02.021. Epub 2012 Mar 3.

PMID:
22406264
49.

A novel mutation in the LMNA gene causes congenital muscular dystrophy with dropped head and brain involvement.

Hattori A, Komaki H, Kawatani M, Sakuma H, Saito Y, Nakagawa E, Sugai K, Sasaki M, Hayashi YK, Nonaka I, Nishino I.

Neuromuscul Disord. 2012 Feb;22(2):149-51. doi: 10.1016/j.nmd.2011.08.009. Epub 2012 Jan 11.

PMID:
22240398
50.

Focal EEG abnormalities might reflect neuropathological characteristics of pervasive developmental disorder and attention-deficit/hyperactivity disorder.

Kawatani M, Hiratani M, Kometani H, Nakai A, Tsukahara H, Tomoda A, Mayumi M, Ohshima Y.

Brain Dev. 2012 Oct;34(9):723-30. doi: 10.1016/j.braindev.2011.11.009. Epub 2012 Jan 4.

PMID:
22225922

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