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Items: 1 to 50 of 96

1.

Sphingosine Kinase 1 expression in peritoneal macrophages is required for colon carcinogenesis.

Furuya H, Tamashiro PM, Shimizu Y, Iino K, Peres R, Chen R, Sun Y, Hannun YA, Obeid LM, Kawamori T.

Carcinogenesis. 2017 Dec 7;38(12):1218-1227. doi: 10.1093/carcin/bgx104.

2.

Genetic deletion of sphingosine kinase 1 suppresses mouse breast tumor development in an HER2 transgenic model.

Shimizu Y, Furuya H, Tamashiro PM, Iino K, Chan OTM, Goodison S, Pagano I, Hokutan K, Peres R, Loo LWM, Hernandez B, Naing A, Chong CDK, Rosser CJ, Kawamori T.

Carcinogenesis. 2018 Jan 12;39(1):47-55. doi: 10.1093/carcin/bgx097.

3.

Erratum to: Inhibition of TRPM7 suppresses cell proliferation of colon adenocarcinoma in vitro and induces hypomagnesemia in vivo without affecting azoxymethane-induced early colon cancer in mice.

Huang J, Furuya H, Faouzi M, Zhang Z, Monteilh-Zoller M, Kawabata KG, David Horgen F, Kawamori T, Penner R, Fleig A.

Cell Commun Signal. 2017 Sep 11;15(1):31. doi: 10.1186/s12964-017-0188-8. No abstract available.

4.

Inhibition of TRPM7 suppresses cell proliferation of colon adenocarcinoma in vitro and induces hypomagnesemia in vivo without affecting azoxymethane-induced early colon cancer in mice.

Huang J, Furuya H, Faouzi M, Zhang Z, Monteilh-Zoller M, Kawabata KG, Horgen FD, Kawamori T, Penner R, Fleig A.

Cell Commun Signal. 2017 Aug 15;15(1):30. doi: 10.1186/s12964-017-0187-9. Erratum in: Cell Commun Signal. 2017 Sep 11;15(1):31.

5.

Sphingosine kinase 1 expression enhances colon tumor growth.

Furuya H, Shimizu Y, Tamashiro PM, Iino K, Bielawski J, Chan OTM, Pagano I, Kawamori T.

J Transl Med. 2017 Jun 6;15(1):120. doi: 10.1186/s12967-017-1220-x.

6.

Role of neutral ceramidase in colon cancer.

García-Barros M, Coant N, Kawamori T, Wada M, Snider AJ, Truman JP, Wu BX, Furuya H, Clarke CJ, Bialkowska AB, Ghaleb A, Yang VW, Obeid LM, Hannun YA.

FASEB J. 2016 Dec;30(12):4159-4171. Epub 2016 Sep 8.

7.

Distinct roles for hematopoietic and extra-hematopoietic sphingosine kinase-1 in inflammatory bowel disease.

Snider AJ, Ali WH, Sticca JA, Coant N, Ghaleb AM, Kawamori T, Yang VW, Hannun YA, Obeid LM.

PLoS One. 2014 Dec 2;9(12):e113998. doi: 10.1371/journal.pone.0113998. eCollection 2014.

8.

Sphingosine kinase 1 mediates head & neck squamous cell carcinoma invasion through sphingosine 1-phosphate receptor 1.

Tamashiro PM, Furuya H, Shimizu Y, Kawamori T.

Cancer Cell Int. 2014 Aug 29;14(1):76. doi: 10.1186/s12935-014-0076-x. eCollection 2014.

9.

Prevention of familial adenomatous polyp development in APC min mice and azoxymethane-induced colon carcinogenesis in F344 Rats by ω-3 fatty acid rich perilla oil.

Rao CV, Patlolla JM, Cooma I, Kawamori T, Steele VE.

Nutr Cancer. 2013;65 Suppl 1:54-60. doi: 10.1080/01635581.2013.785009.

PMID:
23682783
10.

The impact of sphingosine kinase-1 in head and neck cancer.

Tamashiro PM, Furuya H, Shimizu Y, Iino K, Kawamori T.

Biomolecules. 2013 Aug 12;3(3):481-513. doi: 10.3390/biom3030481.

11.

Effect of sphingosine kinase 1 inhibition on blood pressure.

Furuya H, Wada M, Shimizu Y, Yamada PM, Hannun YA, Obeid LM, Kawamori T.

FASEB J. 2013 Feb;27(2):656-64. doi: 10.1096/fj.12-219014. Epub 2012 Oct 29.

12.

Loss of neutral ceramidase increases inflammation in a mouse model of inflammatory bowel disease.

Snider AJ, Wu BX, Jenkins RW, Sticca JA, Kawamori T, Hannun YA, Obeid LM.

Prostaglandins Other Lipid Mediat. 2012 Dec;99(3-4):124-30. doi: 10.1016/j.prostaglandins.2012.08.003. Epub 2012 Aug 31.

13.

Communication between host organism and cancer cells is transduced by systemic sphingosine kinase 1/sphingosine 1-phosphate signalling to regulate tumour metastasis.

Ponnusamy S, Selvam SP, Mehrotra S, Kawamori T, Snider AJ, Obeid LM, Shao Y, Sabbadini R, Ogretmen B.

EMBO Mol Med. 2012 Aug;4(8):761-75. doi: 10.1002/emmm.201200244. Epub 2012 Jun 18.

14.

Sphingolipids in cancer.

Furuya H, Shimizu Y, Kawamori T.

Cancer Metastasis Rev. 2011 Dec;30(3-4):567-76. doi: 10.1007/s10555-011-9304-1. Review.

PMID:
22005951
15.

A role of sphingosine kinase 1 in head and neck carcinogenesis.

Shirai K, Kaneshiro T, Wada M, Furuya H, Bielawski J, Hannun YA, Obeid LM, Ogretmen B, Kawamori T.

Cancer Prev Res (Phila). 2011 Mar;4(3):454-62. doi: 10.1158/1940-6207.CAPR-10-0299. Epub 2011 Jan 5.

16.

Animal models for studying the pathophysiology of ceramide.

Kawamori T.

Adv Exp Med Biol. 2010;688:109-17. Review.

PMID:
20919649
17.

Inhibition of prostaglandin E(2) signaling through the EP(1) receptor does not affect prostacyclin production in human endothelial cells.

Kaneshiro T, Okumura M, Maalouf S, Uflacker A, Maruyama T, Kawamori T.

Prostaglandins Other Lipid Mediat. 2009 Nov;90(1-2):31-6. doi: 10.1016/j.prostaglandins.2009.07.003. Epub 2009 Jul 30.

18.

Role for sphingosine kinase 1 in colon carcinogenesis.

Kawamori T, Kaneshiro T, Okumura M, Maalouf S, Uflacker A, Bielawski J, Hannun YA, Obeid LM.

FASEB J. 2009 Feb;23(2):405-14. doi: 10.1096/fj.08-117572. Epub 2008 Sep 29.

19.

A role for sphingosine kinase 1 in dextran sulfate sodium-induced colitis.

Snider AJ, Kawamori T, Bradshaw SG, Orr KA, Gilkeson GS, Hannun YA, Obeid LM.

FASEB J. 2009 Jan;23(1):143-52. doi: 10.1096/fj.08-118109. Epub 2008 Sep 24.

20.

Cancer chemopreventive properties of orally bioavailable flavonoids--methylated versus unmethylated flavones.

Walle T, Ta N, Kawamori T, Wen X, Tsuji PA, Walle UK.

Biochem Pharmacol. 2007 May 1;73(9):1288-96. Epub 2006 Dec 28.

21.

Acid ceramidase but not acid sphingomyelinase is required for tumor necrosis factor-{alpha}-induced PGE2 production.

Zeidan YH, Pettus BJ, Elojeimy S, Taha T, Obeid LM, Kawamori T, Norris JS, Hannun YA.

J Biol Chem. 2006 Aug 25;281(34):24695-703. Epub 2006 Jun 27.

22.

Sphingosine kinase 1 is up-regulated in colon carcinogenesis.

Kawamori T, Osta W, Johnson KR, Pettus BJ, Bielawski J, Tanaka T, Wargovich MJ, Reddy BS, Hannun YA, Obeid LM, Zhou D.

FASEB J. 2006 Feb;20(2):386-8. Epub 2005 Nov 30.

PMID:
16319132
23.

The coordination of prostaglandin E2 production by sphingosine-1-phosphate and ceramide-1-phosphate.

Pettus BJ, Kitatani K, Chalfant CE, Taha TA, Kawamori T, Bielawski J, Obeid LM, Hannun YA.

Mol Pharmacol. 2005 Aug;68(2):330-5. Epub 2005 May 17.

PMID:
15900018
24.

Prostaglandin E receptor subtype EP(1) deficiency inhibits colon cancer development.

Kawamori T, Kitamura T, Watanabe K, Uchiya N, Maruyama T, Narumiya S, Sugimura T, Wakabayashi K.

Carcinogenesis. 2005 Feb;26(2):353-7. Epub 2004 Nov 25.

PMID:
15564292
25.

Downregulation of prostaglandin E receptor subtype EP3 during colon cancer development.

Shoji Y, Takahashi M, Kitamura T, Watanabe K, Kawamori T, Maruyama T, Sugimoto Y, Negishi M, Narumiya S, Sugimura T, Wakabayashi K.

Gut. 2004 Aug;53(8):1151-8.

26.

Carcinogenicity of aminophenylnorharman, a possible novel endogenous mutagen, formed from norharman and aniline, in F344 rats.

Kawamori T, Totsuka Y, Uchiya N, Kitamura T, Shibata H, Sugimura T, Wakabayashi K.

Carcinogenesis. 2004 Oct;25(10):1967-72. Epub 2004 May 13.

PMID:
15142889
27.

Evidence of alterations in base excision repair of oxidative DNA damage during spontaneous hepatocarcinogenesis in Long Evans Cinnamon rats.

Choudhury S, Zhang R, Frenkel K, Kawamori T, Chung FL, Roy R.

Cancer Res. 2003 Nov 15;63(22):7704-7.

28.

Characterization of dysplastic aberrant crypt foci in the rat colon induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.

Ochiai M, Ushigome M, Fujiwara K, Ubagai T, Kawamori T, Sugimura T, Nagao M, Nakagama H.

Am J Pathol. 2003 Oct;163(4):1607-14.

29.

Enhancement of colon carcinogenesis by prostaglandin E2 administration.

Kawamori T, Uchiya N, Sugimura T, Wakabayashi K.

Carcinogenesis. 2003 May;24(5):985-90.

PMID:
12771044
30.

Chemopreventive effects of nimesulide, a selective cyclooxygenase-2 inhibitor, against PhIP-induced mammary carcinogenesis.

Kawamori T, Nakatsugi S, Ohta T, Sugimura T, Wakabayashi K.

Adv Exp Med Biol. 2002;507:371-6. No abstract available.

PMID:
12664612
31.

Preventive effects of Cladosiphon fucoidan against Helicobacter pylori infection in Mongolian gerbils.

Shibata H, Iimuro M, Uchiya N, Kawamori T, Nagaoka M, Ueyama S, Hashimoto S, Yokokura T, Sugimura T, Wakabayashi K.

Helicobacter. 2003 Feb;8(1):59-65.

PMID:
12603617
32.

A cyclooxygenase-2 inhibitor, nimesulide, inhibits postinitiation phase of N-nitrosobis(2-oxopropyl)amine-induced pancreatic carcinogenesis in hamsters.

Furukawa F, Nishikawa A, Lee IS, Kanki K, Umemura T, Okazaki K, Kawamori T, Wakabayashi K, Hirose M.

Int J Cancer. 2003 Apr 10;104(3):269-73.

33.

Peroxisome proliferator-activated receptor gamma ligands suppress colon carcinogenesis induced by azoxymethane in mice.

Osawa E, Nakajima A, Wada K, Ishimine S, Fujisawa N, Kawamori T, Matsuhashi N, Kadowaki T, Ochiai M, Sekihara H, Nakagama H.

Gastroenterology. 2003 Feb;124(2):361-7.

PMID:
12557142
34.

A COX-2 inhibitor, nimesulide, inhibits chemically-induced rat tongue carcinogenesis through suppression of cell proliferation activity and COX-2 and iNOS expression.

Yoshida K, Tanaka T, Kohno H, Sakata K, Kawamori T, Mori H, Wakabayashi K.

Histol Histopathol. 2003 Jan;18(1):39-48. doi: 10.14670/HH-18.39.

PMID:
12507282
35.

Suppressive effects of garlic extract on Helicobacter pylori-induced gastritis in Mongolian gerbils.

Iimuro M, Shibata H, Kawamori T, Matsumoto T, Arakawa T, Sugimura T, Wakabayashi K.

Cancer Lett. 2002 Dec 10;187(1-2):61-8.

PMID:
12359352
36.

Inhibitory effects of mofezolac, a cyclooxygenase-1 selective inhibitor, on intestinal carcinogenesis.

Kitamura T, Kawamori T, Uchiya N, Itoh M, Noda T, Matsuura M, Sugimura T, Wakabayashi K.

Carcinogenesis. 2002 Sep;23(9):1463-6.

PMID:
12189188
37.

COX-2 and prostanoid receptors: good targets for chemoprevention.

Kawamori T, Wakabayashi K.

J Environ Pathol Toxicol Oncol. 2002;21(2):149-53.

PMID:
12086401
38.

Evaluation of a selective prostaglandin E receptor EP1 antagonist for potential properties in colon carcinogenesis.

Kawamori T, Uchiya N, Kitamura T, Ohuchida S, Yamamoto H, Maruyama T, Sugimura T, Wakabayashi K.

Anticancer Res. 2001 Nov-Dec;21(6A):3865-9.

PMID:
11911260
39.

Involvement of prostaglandin E receptor subtype EP(4) in colon carcinogenesis.

Mutoh M, Watanabe K, Kitamura T, Shoji Y, Takahashi M, Kawamori T, Tani K, Kobayashi M, Maruyama T, Kobayashi K, Ohuchida S, Sugimoto Y, Narumiya S, Sugimura T, Wakabayashi K.

Cancer Res. 2002 Jan 1;62(1):28-32.

40.
41.

Chemopreventive effects of ONO-8711, a selective prostaglandin E receptor EP(1) antagonist, on breast cancer development.

Kawamori T, Uchiya N, Nakatsugi S, Watanabe K, Ohuchida S, Yamamoto H, Maruyama T, Kondo K, Sugimura T, Wakabayashi K.

Carcinogenesis. 2001 Dec;22(12):2001-4.

PMID:
11751431
42.

Testicular toxicity in F344 rats by aminophenylnorharman, formed from norharman and aniline.

Totsuka Y, Kawamori T, Hisada S, Mitsumori K, Ishihara J, Sugimura T, Wakabayashi K.

Toxicol Appl Pharmacol. 2001 Sep 1;175(2):169-75.

PMID:
11543649
43.

High susceptibility of Scid mice to colon carcinogenesis induced by azoxymethane indicates a possible caretaker role for DNA-dependent protein kinase.

Ochiai M, Ubagai T, Kawamori T, Imai H, Sugimura T, Nakagama H.

Carcinogenesis. 2001 Sep;22(9):1551-5.

PMID:
11532879
44.

Marked reduction of Helicobacter pylori-induced gastritis by urease inhibitors, acetohydroxamic acid and flurofamide, in Mongolian gerbils.

Ohta T, Shibata H, Kawamori T, Iimuro M, Sugimura T, Wakabayashi K.

Biochem Biophys Res Commun. 2001 Jul 20;285(3):728-33.

PMID:
11453654
45.

COX-2 and iNOS, good targets for chemoprevention of colon cancer.

Watanabe K, Kawamori T, Nakatsugi S, Wakabayashi K.

Biofactors. 2000;12(1-4):129-33. Review.

PMID:
11216473
46.

Induction of liver preneoplastic lesions by aminophenylnorharman, formed from norharman and aniline, in male F344 rats.

Kawamori T, Totsuka Y, Ishihara J, Uchiya N, Sugimura T, Wakabayashi K.

Cancer Lett. 2001 Feb 26;163(2):157-61.

PMID:
11165749
47.

Effects of heterocyclic amines with mammary gland carcinogenic potential on estrogenic response of uterus in ovariectomized rats.

Kawamori T, Uchiya N, Watanabe K, Ohta T, Sugimura T, Wakabayashi K.

Cancer Lett. 2001 Jan 10;162(1):31-7.

PMID:
11121860
48.

Chemoprevention by nimesulide, a selective cyclooxygenase-2 inhibitor, of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced mammary gland carcinogenesis in rats.

Nakatsugi S, Ohta T, Kawamori T, Mutoh M, Tanigawa T, Watanabe K, Sugie S, Sugimura T, Wakabayashi K.

Jpn J Cancer Res. 2000 Sep;91(9):886-92.

49.

Marked enhancement by fish meal of Helicobacter pylori-induced gastritis in Mongolian gerbils.

Tanigawa T, Kawamori T, Iimuro M, Ohta T, Higuchi K, Arakawa T, Sugimura T, Wakabayashi K.

Jpn J Cancer Res. 2000 Aug;91(8):769-73.

50.

Altered expression of beta-catenin, inducible nitric oxide synthase and cyclooxygenase-2 in azoxymethane-induced rat colon carcinogenesis.

Takahashi M, Mutoh M, Kawamori T, Sugimura T, Wakabayashi K.

Carcinogenesis. 2000 Jul;21(7):1319-27.

PMID:
10874009

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