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Items: 1 to 50 of 141

1.

Novel Compound Induces Erythropoietin Secretion through Liver Effects in Chronic Kidney Disease Patients and Healthy Volunteers.

Shinfuku A, Shimazaki T, Fujiwara M, Sato F, Watase H, Numazaki T, Kawakita Y, Mutoh M, Yamasaki H, Takayama N, Kato S, Sugimoto T, Maruyama J.

Am J Nephrol. 2018;48(3):157-164. doi: 10.1159/000492181. Epub 2018 Sep 3.

2.

Promotion and inhibition of synchronous glycolytic oscillations in yeast by chitosan.

Shibata K, Amemiya T, Kawakita Y, Obase K, Itoh K, Takinoue M, Nakata S, Yamaguchi T.

FEBS J. 2018 Jul;285(14):2679-2690. doi: 10.1111/febs.14513. Epub 2018 May 28.

PMID:
29782686
3.

Anti-tumor efficacy of a novel CLK inhibitor via targeting RNA splicing and MYC-dependent vulnerability.

Iwai K, Yaguchi M, Nishimura K, Yamamoto Y, Tamura T, Nakata D, Dairiki R, Kawakita Y, Mizojiri R, Ito Y, Asano M, Maezaki H, Nakayama Y, Kaishima M, Hayashi K, Teratani M, Miyakawa S, Iwatani M, Miyamoto M, Klein MG, Lane W, Snell G, Tjhen R, He X, Pulukuri S, Nomura T.

EMBO Mol Med. 2018 Jun;10(6). pii: e8289. doi: 10.15252/emmm.201708289.

4.

TLR3 expression status predicts prognosis in patients with advanced thoracic esophageal squamous cell carcinoma after esophagectomy.

Sato Y, Motoyama S, Wakita A, Kawakita Y, Liu J, Nagaki Y, Nanjo H, Terata K, Imai K, Saito H, Minamiya Y.

Am J Surg. 2018 Aug;216(2):319-325. doi: 10.1016/j.amjsurg.2018.01.038. Epub 2018 Feb 1.

PMID:
29395019
5.

Liquid-like thermal conduction in intercalated layered crystalline solids.

Li B, Wang H, Kawakita Y, Zhang Q, Feygenson M, Yu HL, Wu D, Ohara K, Kikuchi T, Shibata K, Yamada T, Ning XK, Chen Y, He JQ, Vaknin D, Wu RQ, Nakajima K, Kanatzidis MG.

Nat Mater. 2018 Mar;17(3):226-230. doi: 10.1038/s41563-017-0004-2. Epub 2018 Jan 15.

PMID:
29335610
6.

Efficacy and Safety of Neoadjuvant Chemoradiotherapy Following Esophagectomy with Japanese-style Extended 3-Field Lymphadenectomy for Thoracic Esophageal Cancer.

Motoyama S, Sato Y, Sasaki T, Wakita A, Kawakita Y, Liu J, Nagaki Y, Saito H, Imai K, Konno H, Mizusawa KT, Minamiya Y.

Anticancer Res. 2017 Oct;37(10):5837-5843.

PMID:
28982909
7.

Metabolic Rather than Pathological Response to Preoperative Chemoradiotherapy Is a Stronger Predictor of Survival in cStage IIB-IV Esophageal Cancer.

Motoyama S, Sato Y, Maruyama K, Usami S, Yoshino K, Nakatsu T, Sasaki T, Wakita A, Kawakita Y, Liu J, Anbai A, Ishiyama K, Saito H, Minamiya Y.

Anticancer Res. 2017 Aug;37(8):4189-4194.

PMID:
28739705
8.

Polar rotor scattering as atomic-level origin of low mobility and thermal conductivity of perovskite CH3NH3PbI3.

Li B, Kawakita Y, Liu Y, Wang M, Matsuura M, Shibata K, Ohira-Kawamura S, Yamada T, Lin S, Nakajima K, Liu SF.

Nat Commun. 2017 Jun 30;8:16086. doi: 10.1038/ncomms16086.

9.

Discovery of Novel and Potent Stearoyl Coenzyme A Desaturase 1 (SCD1) Inhibitors as Anticancer Agents.

Imamura K, Tomita N, Kawakita Y, Ito Y, Ono K, Nii N, Miyazaki T, Yonemori K, Tawada M, Sumi H, Satoh Y, Yamamoto Y, Miyahisa I, Sasaki M, Satomi Y, Hirayama M, Nishigaki R, Maezaki H.

Bioorg Med Chem. 2017 Jul 15;25(14):3768-3779. doi: 10.1016/j.bmc.2017.05.016. Epub 2017 May 11.

PMID:
28571972
10.

Sphingosine-1-phosphate/sphingosine kinase 1-dependent lymph node metastasis in esophageal squamous cell carcinoma.

Kawakita Y, Motoyama S, Sato Y, Koyota S, Wakita A, Liu J, Saito H, Minamiya Y.

Surg Today. 2017 Nov;47(11):1312-1320. doi: 10.1007/s00595-017-1514-x. Epub 2017 Mar 31.

PMID:
28364399
11.

PD-L1 Expression Is a Prognostic Factor in Patients with Thoracic Esophageal Cancer Treated Without Adjuvant Chemotherapy.

Wakita A, Motoyama S, Nanjo H, Sato Y, Yoshino K, Sasaki T, Kawakita Y, Liu J, Imai K, Saito H, Minamiya Y.

Anticancer Res. 2017 Mar;37(3):1433-1441.

PMID:
28314315
12.

Decreased Skeletal Muscle Mass After Neoadjuvant Therapy Correlates with Poor Prognosis in Patients with Esophageal Cancer.

Liu J, Motoyama S, Sato Y, Wakita A, Kawakita Y, Saito H, Minamiya Y.

Anticancer Res. 2016 Dec;36(12):6677-6685.

PMID:
27920002
13.

Ultrasound-guided intranodal lipiodol lymphangiography from the groin is useful for assessment and treatment of post-esophagectomy chylothorax in three cases.

Liu J, Sato Y, Motoyama S, Ishiyama K, Yamada K, Yamamoto M, Wakita A, Kawakita Y, Imai K, Saito H, Hashimoto M, Minamiya Y.

Int J Surg Case Rep. 2016;29:103-107. doi: 10.1016/j.ijscr.2016.10.069. Epub 2016 Nov 3.

14.
15.

The structure of molten CuCl: Reverse Monte Carlo modeling with high-energy X-ray diffraction data and molecular dynamics of a polarizable ion model.

Alcaraz O, Trullàs J, Tahara S, Kawakita Y, Takeda S.

J Chem Phys. 2016 Sep 7;145(9):094503. doi: 10.1063/1.4962181.

PMID:
27609000
16.

Discovery of 3-Chloro-N-{(S)-[3-(1-ethyl-1H-pyrazol-4-yl)phenyl][(2S)-piperidine-2-yl]methyl}-4-(trifluoromethyl)pyridine-2-carboxamide as a Potent Glycine Transporter 1 Inhibitor.

Yamamoto S, Shibata T, Abe K, Oda K, Aoki T, Kawakita Y, Kawamoto H.

Chem Pharm Bull (Tokyo). 2016;64(9):1321-37. doi: 10.1248/cpb.c16-00314.

17.

Structural Study of MPN387, an Essential Protein for Gliding Motility of a Human-Pathogenic Bacterium, Mycoplasma pneumoniae.

Kawakita Y, Kinoshita M, Furukawa Y, Tulum I, Tahara YO, Katayama E, Namba K, Miyata M.

J Bacteriol. 2016 Aug 11;198(17):2352-9. doi: 10.1128/JB.00160-16. Print 2016 Sep 1.

18.

Esophageal Cancer Patients Have a High Incidence of Severe Periodontitis and Preoperative Dental Care Reduces the Likelihood of Severe Pneumonia after Esophagectomy.

Sato Y, Motoyama S, Takano H, Nakata A, Liu J, Harimaya D, Todo N, Yoshino K, Sasaki T, Wakita A, Kawakita Y, Imai K, Saito H, Fukuda M, Minamiya Y.

Dig Surg. 2016;33(6):495-502. doi: 10.1159/000446927. Epub 2016 Jun 10.

PMID:
27287475
19.

Inelastic and quasi-elastic neutron scattering spectrometers in J-PARC.

Seto H, Itoh S, Yokoo T, Endo H, Nakajima K, Shibata K, Kajimoto R, Ohira-Kawamura S, Nakamura M, Kawakita Y, Nakagawa H, Yamada T.

Biochim Biophys Acta Gen Subj. 2017 Jan;1861(1 Pt B):3651-3660. doi: 10.1016/j.bbagen.2016.04.025. Epub 2016 May 6.

20.

Highly efficient chip-scale III-V/silicon hybrid optical amplifiers.

Cheung S, Kawakita Y, Shang K, Yoo SJ.

Opt Express. 2015 Aug 24;23(17):22431-43. doi: 10.1364/OE.23.022431.

PMID:
26368213
21.

Intermediate-range chemical ordering of cations in molten RbCl-AgCl.

Tahara S, Kawakita Y, Shimakura H, Ohara K, Fukami T, Takeda S.

J Chem Phys. 2015 Jul 28;143(4):044509. doi: 10.1063/1.4927507.

PMID:
26233147
22.

Efficacy of a glycine transporter 1 inhibitor TASP0315003 in animal models of cognitive dysfunction and negative symptoms of schizophrenia.

Chaki S, Shimazaki T, Karasawa J, Aoki T, Kaku A, Iijima M, Kambe D, Yamamoto S, Kawakita Y, Shibata T, Abe K, Okubo T, Sekiguchi Y, Okuyama S.

Psychopharmacology (Berl). 2015 Aug;232(15):2849-61. doi: 10.1007/s00213-015-3920-3. Epub 2015 Apr 15.

PMID:
25869273
23.

A double-blind, block-randomized, placebo-controlled trial to identify the chemical assistance effect of mesna submucosal injection for gastric endoscopic submucosal dissection.

Sumiyama K, Toyoizumi H, Ohya TR, Dobashi A, Hino S, Kobayashi M, Goda K, Imazu H, Kawakita Y, Kato T, Tajiri H.

Gastrointest Endosc. 2014 May;79(5):756-64. doi: 10.1016/j.gie.2013.09.027. Epub 2013 Nov 12.

PMID:
24238308
24.

Inter-molecular correlations in liquid Se2Br2.

Shimakura H, Kawakita Y, Ohara K, Pusztai L, Wakisaka Y, Takeda S.

J Phys Condens Matter. 2013 Nov 13;25(45):454221. doi: 10.1088/0953-8984/25/45/454221. Epub 2013 Oct 18.

PMID:
24140925
25.

Antitumor Activity of TAK-285, an Investigational, Non-Pgp Substrate HER2/EGFR Kinase Inhibitor, in Cultured Tumor Cells, Mouse and Rat Xenograft Tumors, and in an HER2-Positive Brain Metastasis Model.

Nakayama A, Takagi S, Yusa T, Yaguchi M, Hayashi A, Tamura T, Kawakita Y, Ishikawa T, Ohta Y.

J Cancer. 2013 Aug 16;4(7):557-65. doi: 10.7150/jca.6689. eCollection 2013.

26.

Mode-distribution analysis of quasielastic neutron scattering and application to liquid water.

Kikuchi T, Nakajima K, Ohira-Kawamura S, Inamura Y, Yamamuro O, Kofu M, Kawakita Y, Suzuya K, Nakamura M, Arai M.

Phys Rev E Stat Nonlin Soft Matter Phys. 2013 Jun;87(6):062314. Epub 2013 Jun 19.

PMID:
23848682
27.

Design and synthesis of novel pyrimido[4,5-b]azepine derivatives as HER2/EGFR dual inhibitors.

Kawakita Y, Seto M, Ohashi T, Tamura T, Yusa T, Miki H, Iwata H, Kamiguchi H, Tanaka T, Sogabe S, Ohta Y, Ishikawa T.

Bioorg Med Chem. 2013 Apr 15;21(8):2250-2261. doi: 10.1016/j.bmc.2013.02.014. Epub 2013 Feb 22.

PMID:
23490150
28.

Structure-Based Approach for the Discovery of Pyrrolo[3,2-d]pyrimidine-Based EGFR T790M/L858R Mutant Inhibitors.

Sogabe S, Kawakita Y, Igaki S, Iwata H, Miki H, Cary DR, Takagi T, Takagi S, Ohta Y, Ishikawa T.

ACS Med Chem Lett. 2012 Dec 18;4(2):201-5. doi: 10.1021/ml300327z. eCollection 2013 Feb 14.

29.

Design and synthesis of pyrrolo[3,2-d]pyrimidine HER2/EGFR dual inhibitors: improvement of the physicochemical and pharmacokinetic profiles for potent in vivo anti-tumor efficacy.

Kawakita Y, Miwa K, Seto M, Banno H, Ohta Y, Tamura T, Yusa T, Miki H, Kamiguchi H, Ikeda Y, Tanaka T, Kamiyama K, Ishikawa T.

Bioorg Med Chem. 2012 Oct 15;20(20):6171-80. doi: 10.1016/j.bmc.2012.08.002. Epub 2012 Aug 25.

PMID:
22980219
30.

Characterization of each aefR and mexT mutant in Pseudomonas syringae pv. tabaci 6605.

Kawakita Y, Taguchi F, Inagaki Y, Toyoda K, Shiraishi T, Ichinose Y.

Mol Genet Genomics. 2012 Jun;287(6):473-84. doi: 10.1007/s00438-012-0693-9. Epub 2012 May 3.

PMID:
22552803
31.

Design and synthesis of pyrrolo[3,2-d]pyrimidine human epidermal growth factor receptor 2 (HER2)/epidermal growth factor receptor (EGFR) dual inhibitors: exploration of novel back-pocket binders.

Kawakita Y, Banno H, Ohashi T, Tamura T, Yusa T, Nakayama A, Miki H, Iwata H, Kamiguchi H, Tanaka T, Habuka N, Sogabe S, Ohta Y, Ishikawa T.

J Med Chem. 2012 Apr 26;55(8):3975-91. doi: 10.1021/jm300185p. Epub 2012 Apr 10.

PMID:
22439974
32.

Design and synthesis of novel human epidermal growth factor receptor 2 (HER2)/epidermal growth factor receptor (EGFR) dual inhibitors bearing a pyrrolo[3,2-d]pyrimidine scaffold.

Ishikawa T, Seto M, Banno H, Kawakita Y, Oorui M, Taniguchi T, Ohta Y, Tamura T, Nakayama A, Miki H, Kamiguchi H, Tanaka T, Habuka N, Sogabe S, Yano J, Aertgeerts K, Kamiyama K.

J Med Chem. 2011 Dec 8;54(23):8030-50. doi: 10.1021/jm2008634. Epub 2011 Nov 4.

PMID:
22003817
33.

Medium-range correlation of Ag ions in superionic melts of Ag2Se and AgI by reverse Monte Carlo structural modelling-connectivity and void distribution.

Tahara S, Ueno H, Ohara K, Kawakita Y, Kohara S, Ohno S, Takeda S.

J Phys Condens Matter. 2011 Jun 15;23(23):235102. doi: 10.1088/0953-8984/23/23/235102. Epub 2011 May 25.

PMID:
21613697
34.

Visual experience influences 12-month-old infants' perception of goal-directed actions of others.

Myowa-Yamakoshi M, Kawakita Y, Okanda M, Takeshita H.

Dev Psychol. 2011 Jul;47(4):1042-9. doi: 10.1037/a0023765.

PMID:
21604864
35.

Structural disorder in lithium lanthanum titanate: the basis of superionic conduction.

Ohara K, Kawakita Y, Pusztai L, Temleitner L, Kohara S, Inoue N, Takeda S.

J Phys Condens Matter. 2010 Oct 13;22(40):404203. doi: 10.1088/0953-8984/22/40/404203. Epub 2010 Sep 22.

PMID:
21386564
36.

Effects of glucose and amino acids on ghrelin secretion in sheep.

Sugino T, Kawakita Y, Fukumori R, Hasegawa Y, Kojima M, Kangawa K, Obitsu T, Taniguchi K.

Anim Sci J. 2010 Apr;81(2):199-204. doi: 10.1111/j.1740-0929.2009.00733.x.

PMID:
20438501
37.

(1S)-1,5-anhydro-1-[5-(4-ethoxybenzyl)-2-methoxy-4-methylphenyl]-1-thio-D-glucitol (TS-071) is a potent, selective sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor for type 2 diabetes treatment.

Kakinuma H, Oi T, Hashimoto-Tsuchiya Y, Arai M, Kawakita Y, Fukasawa Y, Iida I, Hagima N, Takeuchi H, Chino Y, Asami J, Okumura-Kitajima L, Io F, Yamamoto D, Miyata N, Takahashi T, Uchida S, Yamamoto K.

J Med Chem. 2010 Apr 22;53(8):3247-61. doi: 10.1021/jm901893x.

PMID:
20302302
38.

The structure of molten CuCl, CuI and their mixtures as investigated by using neutron diffraction.

Drewitt JW, Salmon PS, Takeda S, Kawakita Y.

J Phys Condens Matter. 2009 Feb 18;21(7):075104. doi: 10.1088/0953-8984/21/7/075104. Epub 2009 Jan 13.

PMID:
21817319
39.

Synthesis, in vitro pharmacology, and pharmacokinetic profiles of 2-[1-amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-1-fluorocyclopropanecarboxylic acid and its 6-heptyl ester, a potent mGluR2 antagonist.

Sakagami K, Yasuhara A, Chaki S, Yoshikawa R, Kawakita Y, Saito A, Taguchi T, Nakazato A.

Bioorg Med Chem. 2008 Apr 15;16(8):4359-66. doi: 10.1016/j.bmc.2008.02.066. Epub 2008 Feb 26.

PMID:
18348906
40.

4-(Dimethylamino)pyridine N-oxide (DMAPO): an effective nucleophilic catalyst in the peptide coupling reaction with 2-methyl-6-nitrobenzoic anhydride.

Shiina I, Ushiyama H, Yamada YK, Kawakita Y, Nakata K.

Chem Asian J. 2008 Feb 1;3(2):454-61. doi: 10.1002/asia.200700305.

PMID:
18219641
41.

Comparison of partial structures of melts of superionic AgI and CuI and non-superionic AgCl.

Kawakita Y, Tahara S, Fujii H, Kohara S, Takeda S.

J Phys Condens Matter. 2007 Aug 22;19(33):335201. doi: 10.1088/0953-8984/19/33/335201. Epub 2007 Jul 4.

PMID:
21694124
42.

Neutron diffraction data and molecular dynamics simulations of the molten mixture Ag(Br0.7I0.3).

Bitrián V, Trullàs J, Silbert M, Enosaki T, Kawakita Y, Takeda S.

J Chem Phys. 2006 Nov 14;125(18):184510.

PMID:
17115768
43.

The mildest known case of Fukuyama-type congenital muscular dystrophy.

Akiyama T, Ohtsuka Y, Takata T, Hattori J, Kawakita Y, Saito K.

Brain Dev. 2006 Sep;28(8):537-40. Epub 2006 Apr 17.

PMID:
16603329
44.
45.

Total synthesis of buergerinin F via effective construction of the asymmetric quaternary carbons using an enantioselective aldol reaction.

Shiina I, Kawakita Y, Ibuka R, Yokoyama K, Yamai YS.

Chem Commun (Camb). 2005 Aug 28;(32):4062-4. Epub 2005 Jul 14.

PMID:
16091800
46.

Cloning of cDNA encoding a regeneration-associated muscle protease whose expression is attenuated in cell lines derived from Duchenne muscular dystrophy patients.

Nakayama Y, Nara N, Kawakita Y, Takeshima Y, Arakawa M, Katoh M, Morita S, Iwatsuki K, Tanaka K, Okamoto S, Kitamura T, Seki N, Matsuda R, Matsuo M, Saito K, Hara T.

Am J Pathol. 2004 May;164(5):1773-82.

47.

Taxol derivatives are selective inhibitors of DNA polymerase alpha.

Oshige M, Takenouchi M, Kato Y, Kamisuki S, Takeuchi T, Kuramochi K, Shiina I, Suenaga Y, Kawakita Y, Kuroda K, Sato N, Kobayashi S, Sugawara F, Sakaguchi K.

Bioorg Med Chem. 2004 May 15;12(10):2597-601.

PMID:
15110841
48.
49.

Serum leptin levels during the periparturient period in cows.

Soliman M, Ishioka K, Yoshida R, Komabayashi K, Hatai H, Matsui Y, Hirai T, Katagiri S, Takahashi Y, Kawakita Y, Abe H, Kitamura H, Kimura K, Saito M.

J Vet Med Sci. 2002 Nov;64(11):1053-6.

50.

Radioiodination of glycoprotein-conjugated liposomes by using the Bolton-Hunter reagent and biodistribution in tumor-bearing mice.

Shimura N, Sogawa Y, Kawakita Y, Ikekita M, Yamazaki N, Kojima S.

Nucl Med Biol. 2002 May;29(4):491-6.

PMID:
12031885

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