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Items: 1 to 50 of 180

1.

Long-term quality control testing on a high-sensitivity cardiac troponin I assay.

Kavsak PA, MacEachern K, Petryayeva E, Clark L.

Clin Chim Acta. 2019 Aug 13;498:27-29. doi: 10.1016/j.cca.2019.08.006. [Epub ahead of print] No abstract available.

PMID:
31419413
2.

High-sensitivity troponin testing months after an acute coronary syndrome: noise or notable results.

Kavsak P, Devereaux PJ.

Heart. 2019 Aug 12. pii: heartjnl-2019-315434. doi: 10.1136/heartjnl-2019-315434. [Epub ahead of print] No abstract available.

PMID:
31405896
3.

Educational Recommendations on Selected Analytical and Clinical Aspects of Natriuretic Peptides with a Focus on Heart Failure: A Report from the IFCC Committee on Clinical Applications of Cardiac Biomarkers.

Kavsak PA, Lam CSP, Saenger AK, Jaffe AS, Collinson P, Pulkki K, Omland T, Lefèvre G, Body R, Ordonez-Llanos J, Apple FS.

Clin Chem. 2019 Aug 6. pii: clinchem.2019.306621. doi: 10.1373/clinchem.2019.306621. [Epub ahead of print]

PMID:
31387884
4.

The importance of the methodology and sample matrix when interpreting chromogranin A results.

Kavsak PA, Beattie J, Rutledge AC.

Clin Chem Lab Med. 2019 Aug 5. pii: /j/cclm.ahead-of-print/cclm-2019-0358/cclm-2019-0358.xml. doi: 10.1515/cclm-2019-0358. [Epub ahead of print] No abstract available.

PMID:
31377733
5.

High-sensitivity cardiac troponin testing during and after ACS: Complexed or not?

Hwang P, Mingels A, Kavsak PA.

Clin Biochem. 2019 Jul 27. pii: S0009-9120(19)30762-3. doi: 10.1016/j.clinbiochem.2019.07.012. [Epub ahead of print] No abstract available.

PMID:
31361993
6.

Rapid atrophy of cardiac left ventricular mass in patients with non-small cell carcinoma of the lung.

Kazemi-Bajestani SMR, Becher H, Butts C, Basappa NS, Smylie M, Joy AA, Sangha R, Gallivan A, Kavsak P, Chu Q, Baracos VE.

J Cachexia Sarcopenia Muscle. 2019 Jul 10. doi: 10.1002/jcsm.12451. [Epub ahead of print]

7.

A heterophile antibody affecting a contemporary but not a high-sensitivity cardiac troponin assay.

Kavsak PA, Ainsworth C.

Clin Biochem. 2019 Sep;71:72-73. doi: 10.1016/j.clinbiochem.2019.07.004. Epub 2019 Jul 4. No abstract available.

PMID:
31279688
8.

Application of High-Sensitivity Troponin in Suspected Myocardial Infarction.

Neumann JT, Twerenbold R, Ojeda F, Sörensen NA, Chapman AR, Shah ASV, Anand A, Boeddinghaus J, Nestelberger T, Badertscher P, Mokhtari A, Pickering JW, Troughton RW, Greenslade J, Parsonage W, Mueller-Hennessen M, Gori T, Jernberg T, Morris N, Liebetrau C, Hamm C, Katus HA, Münzel T, Landmesser U, Salomaa V, Iacoviello L, Ferrario MM, Giampaoli S, Kee F, Thorand B, Peters A, Borchini R, Jørgensen T, Söderberg S, Sans S, Tunstall-Pedoe H, Kuulasmaa K, Renné T, Lackner KJ, Worster A, Body R, Ekelund U, Kavsak PA, Keller T, Lindahl B, Wild P, Giannitsis E, Than M, Cullen LA, Mills NL, Mueller C, Zeller T, Westermann D, Blankenberg S.

N Engl J Med. 2019 Jun 27;380(26):2529-2540. doi: 10.1056/NEJMoa1803377.

PMID:
31242362
9.

Definitions of post-coronary artery bypass grafting myocardial infarction: variations in incidence and prognostic significance.

Belley-Cote EP, Lamy A, Devereaux PJ, Kavsak P, Lamontagne F, Cook DJ, Kennedy K, Vincent J, Ou Y, Tagarakis G, Whitlock RP.

Eur J Cardiothorac Surg. 2019 Jun 10. pii: ezz161. doi: 10.1093/ejcts/ezz161. [Epub ahead of print]

PMID:
31180497
10.

Four Different High-Sensitivity Cardiac Troponin Assays With Important Analytical Performance Differences.

Kavsak PA, Ainsworth C, Clark L, Devereaux PJ, Worster A.

Can J Cardiol. 2019 Jun;35(6):796.e17-796.e18. doi: 10.1016/j.cjca.2019.03.005. Epub 2019 Mar 19. No abstract available.

PMID:
31151719
11.

Analytical characterization of the Siemens Dimension EXL high-sensitivity cardiac troponin I assay.

Kavsak PA, MacCuish J, Boreyko J, Roy C, Lamers S, Clark L.

Clin Biochem. 2019 Jul;69:52-56. doi: 10.1016/j.clinbiochem.2019.05.001. Epub 2019 May 4.

PMID:
31063741
12.

A post-hoc subgroup analysis assessing acute cardiac biomarker profiles in female cancer patients during adjuvant therapy.

Mackett K, Dhesy-Thind S, Donovan EK, Mukherjee S, Swaminath A, Leong DP, Voruganti S, Sussman J, Wright J, Okawara G, Fraser G, Sagar S, Bordeleau L, Ellis PM, Hirte H, Kavsak PA.

Clin Chim Acta. 2019 Aug;495:355-357. doi: 10.1016/j.cca.2019.04.083. Epub 2019 May 2. No abstract available.

PMID:
31054914
13.

The PROTROPIC feasibility study: prognostic value of elevated troponins in critical illness.

Belley-Cote EP, Whitlock RP, Ulic DV, Honarmand K, Khalifa A, McClure GR, Gibson A, Alshamsi F, D'Aragon F, Rochwerg B, Duan E, Savija N, Karachi T, Lamontagne F, Kavsak P, Cook DJ.

Can J Anaesth. 2019 Jun;66(6):648-657. doi: 10.1007/s12630-019-01375-y. Epub 2019 Apr 29.

PMID:
31037586
14.

MEDiastinal Irradiation and CArdio-Toxic Effects (MEDICATE): Exploring the Relationship between Cardiac Irradiation and High Sensitivity Troponins.

Donovan EK, Dhesy-Thind S, Swaminath A, Leong D, Pond G, Voruganti S, Sussman J, Wright JR, Okawara G, Kavsak P, Dokainish H, Fraser G, Sagar SM.

Clin Oncol (R Coll Radiol). 2019 Jul;31(7):479-485. doi: 10.1016/j.clon.2019.04.003. Epub 2019 Apr 25.

PMID:
31031066
15.

Effect of Storage Temperature for B-Type Natriuretic Peptide Concentrations for Primary Healthcare Populations.

Kavsak PA, Beattie J, Ma J.

Clin Chem. 2019 Jun;65(6):811-812. doi: 10.1373/clinchem.2018.300749. Epub 2019 Mar 27. No abstract available.

PMID:
30917973
16.

Longitudinal High-Sensitivity Cardiac Troponin I Measurements in Patients With Breast Cancer Receiving Trastuzumab.

Dhesy-Thind S, Ellis PM, Mukherjee SD, Mackett K, Bordeleau L, Kavsak PA.

Can J Cardiol. 2019 Apr;35(4):545.e1-545.e2. doi: 10.1016/j.cjca.2018.12.023. Epub 2018 Dec 28. No abstract available.

PMID:
30853135
17.

Sample matrix and high-sensitivity cardiac troponin I assays.

Kavsak PA, Roy C, Malinowski P, Clark L, Lamers S, Bamford K, Hill S, Worster A, Jaffe AS.

Clin Chem Lab Med. 2019 Apr 24;57(5):745-751. doi: 10.1515/cclm-2018-1100.

PMID:
30838842
18.

High-Sensitivity Generation 5 Cardiac Troponin T Sex- and Age-Specific 99th Percentiles in the CALIPER Cohort of Healthy Children and Adolescents.

Bohn MK, Higgins V, Kavsak P, Hoffman B, Adeli K.

Clin Chem. 2019 Apr;65(4):589-591. doi: 10.1373/clinchem.2018.299156. Epub 2019 Feb 8. No abstract available.

PMID:
30737206
19.

Between-day versus within-day imprecision using the Abbott high-sensitivity cardiac troponin I assay at concentrations around 5 ng/l.

Kavsak PA, Millar E, McLay G, Clark L, Jaffe AS.

Clin Chim Acta. 2019 Feb;489:58-60. doi: 10.1016/j.cca.2018.11.031. Epub 2018 Nov 28. No abstract available.

PMID:
30502326
20.

Pre-analytical variables affecting discordant results on repeat sample testing for cardiac troponin I.

Kittanakom S, Ly V, Arnoldo A, Beattie A, Kavsak PA.

Clin Biochem. 2019 Jan;63:158-160. doi: 10.1016/j.clinbiochem.2018.10.014. Epub 2018 Oct 28. No abstract available.

PMID:
30393000
21.

Evaluation of the Siemens ADVIA Centaur high-sensitivity cardiac troponin I assay in serum.

Kavsak PA, Worster A, Hill SA, Jaffe AS.

Clin Chim Acta. 2018 Dec;487:216-221. doi: 10.1016/j.cca.2018.10.012. Epub 2018 Oct 6.

PMID:
30296440
22.

Cardiac troponin and natriuretic peptide analytical interferences from hemolysis and biotin: educational aids from the IFCC Committee on Cardiac Biomarkers (IFCC C-CB).

Saenger AK, Jaffe AS, Body R, Collinson PO, Kavsak PA, Lam CSP, Lefèvre G, Omland T, Ordóñez-Llanos J, Pulkki K, Apple FS.

Clin Chem Lab Med. 2019 Apr 24;57(5):633-640. doi: 10.1515/cclm-2018-0905.

23.

Sex-specific, high-sensitivity cardiac troponin T cut-off concentrations for ruling out acute myocardial infarction with a single measurement.

McRae A, Graham M, Abedin T, Ji Y, Yang H, Wang D, Southern D, Andruchow J, Lang E, Innes G, Seiden-Long I, DeKoning L, Kavsak P.

CJEM. 2019 Jan;21(1):26-33. doi: 10.1017/cem.2018.435. Epub 2018 Sep 28.

PMID:
30261938
24.

The importance of tumour marker dual reporting during method transition: PSA high-dose hook effect detected.

Kittanakom S, Donohue V, Beattie J, Clark L, Kavsak PA.

Clin Biochem. 2018 Nov;61:45-46. doi: 10.1016/j.clinbiochem.2018.08.011. Epub 2018 Sep 1. No abstract available.

PMID:
30179593
25.

Clinical chemistry score versus high-sensitivity cardiac troponin I and T tests alone to identify patients at low or high risk for myocardial infarction or death at presentation to the emergency department.

Kavsak PA, Neumann JT, Cullen L, Than M, Shortt C, Greenslade JH, Pickering JW, Ojeda F, Ma J, Clayton N, Sherbino J, Hill SA, McQueen M, Westermann D, Sörensen NA, Parsonage WA, Griffith L, Mehta SR, Devereaux PJ, Richards M, Troughton R, Pemberton C, Aldous S, Blankenberg S, Worster A.

CMAJ. 2018 Aug 20;190(33):E974-E984. doi: 10.1503/cmaj.180144.

26.

Multicenter comparison of imprecision at low concentrations of two regulatory approved high-sensitivity cardiac troponin I assays.

Raizman JE, Fuezery A, Tsui AKY, Higgins T, Goudreau BL, Clark L, Hill SA, Kavsak PA.

Clin Chim Acta. 2018 Nov;486:219-220. doi: 10.1016/j.cca.2018.08.010. Epub 2018 Aug 10. No abstract available.

PMID:
30102897
27.

Perioperative heart-type fatty acid binding protein concentration cutoffs for the identification of severe acute kidney injury in patients undergoing cardiac surgery.

Kavsak PA, Whitlock R, Thiessen-Philbrook H, Parikh CR.

Clin Chem Lab Med. 2018 Dec 19;57(2):e8-e10. doi: 10.1515/cclm-2018-0547. No abstract available.

PMID:
30044762
28.

Differences in total PSA results within and between manufacturers.

Kittanakom S, Clark L, Roy C, Malinowski P, Bamford K, Lamers S, Kavsak PA.

Clin Biochem. 2018 Sep;60:91-92. doi: 10.1016/j.clinbiochem.2018.07.009. Epub 2018 Jul 20. No abstract available.

PMID:
30036511
29.

External Quality Assessment Testing Near the Limit of Detection for High-Sensitivity Cardiac Troponin Assays.

Kavsak PA.

Clin Chem. 2018 Sep;64(9):1402-1404. doi: 10.1373/clinchem.2018.288613. Epub 2018 Jun 29. No abstract available.

30.

Post-exercise cardiac troponin I release and clearance in normal Standardbred racehorses.

Rossi TM, Kavsak PA, Maxie MG, Pearl DL, Pyle WG, Physick-Sheard PW.

Equine Vet J. 2019 Jan;51(1):97-101. doi: 10.1111/evj.12967. Epub 2018 Jun 28.

PMID:
29806966
31.

Should detectable cardiac troponin concentrations in a healthy population be the only criterion for classifying high-sensitivity cardiac troponin assays?

Kavsak PA.

Clin Biochem. 2018 Jun;56:1-3. doi: 10.1016/j.clinbiochem.2018.05.015. Epub 2018 May 24. No abstract available.

PMID:
29803619
32.

Profile of Roche's Elecsys Troponin T Gen 5 STAT blood test (a high-sensitivity cardiac troponin assay) for diagnosing myocardial infarction in the emergency department.

Kavsak PA, Andruchow JE, McRae AD, Worster A.

Expert Rev Mol Diagn. 2018 Jun;18(6):481-489. doi: 10.1080/14737159.2018.1476141. Epub 2018 May 18. Review.

PMID:
29756512
33.

The potential role of a turbidimetric heart-type fatty acid-binding protein assay to aid in the interpretation of persistently elevated, non-changing, cardiac troponin I concentrations.

Kavsak PA, Ainsworth C, Arnold DM, Scott T, Clark L, Ivica J, Mackett K, Whitlock R, Worster A.

Clin Biochem. 2018 Aug;58:53-59. doi: 10.1016/j.clinbiochem.2018.05.006. Epub 2018 May 8.

PMID:
29750937
34.

Assessing matrix, interferences and comparability between the Abbott Diagnostics and the Beckman Coulter high-sensitivity cardiac troponin I assays.

Kavsak PA, Malinowski P, Roy C, Clark L, Lamers S.

Clin Chem Lab Med. 2018 Jun 27;56(7):1176-1181. doi: 10.1515/cclm-2017-1122.

PMID:
29533903
35.

Contemporary Emergency Department Management of Patients with Chest Pain: A Concise Review and Guide for the High-Sensitivity Troponin Era.

Andruchow JE, Kavsak PA, McRae AD.

Can J Cardiol. 2018 Feb;34(2):98-108. doi: 10.1016/j.cjca.2017.11.012. Epub 2017 Dec 2. Review.

PMID:
29407013
36.

Performance of high-sensitivity cardiac troponin in the emergency department for myocardial infarction and a composite cardiac outcome across different estimated glomerular filtration rates.

Kavsak PA, Worster A, Shortt C, Ma J, Clayton N, Sherbino J, Hill SA, McQueen M, Griffith LE, Mehta SR, McRae AD, Devereaux PJ.

Clin Chim Acta. 2018 Apr;479:166-170. doi: 10.1016/j.cca.2018.01.034. Epub 2018 Feb 3.

PMID:
29366835
37.

Development of biomarker combinations for postoperative acute kidney injury via Bayesian model selection in a multicenter cohort study.

Meisner A, Kerr KF, Thiessen-Philbrook H, Wilson FP, Garg AX, Shlipak MG, Kavsak P, Whitlock RP, Coca SG, Parikh CR.

Biomark Res. 2018 Jan 12;6:3. doi: 10.1186/s40364-018-0117-z. eCollection 2018.

39.

Chloride and Other Electrolyte Concentrations in Commonly Available 5% Albumin Products.

Lai AT, Zeller MP, Millen T, Kavsak P, Szczeklik W, Elahie A, Alhazzani W, D'Aragon F, Jaeschke R, Lamontagne F, Karachi T, Cook D, Meade M, Rochwerg B; Canadian Critical Care Trials Group.

Crit Care Med. 2018 Apr;46(4):e326-e329. doi: 10.1097/CCM.0000000000002955.

PMID:
29293151
40.

Variability Between Reagent Lots for High-Sensitivity Cardiac Troponin I May Affect Performance of Early Rule Out Strategies.

Kavsak PA, Worster A, Oliver R, Clark L, Parry D, Randell E, Sarfaraz MO, Hill S, Jaffe AS.

Can J Cardiol. 2018 Feb;34(2):209.e5-209.e6. doi: 10.1016/j.cjca.2017.11.010. Epub 2017 Nov 22. No abstract available.

PMID:
29287942
41.

Analytical validation of cardiac troponin I assays in horses.

Rossi TM, Kavsak PA, Maxie MG, Pearl DL, Pyle WG, Physick-Sheard PW.

J Vet Diagn Invest. 2018 Mar;30(2):226-232. doi: 10.1177/1040638717747070. Epub 2017 Dec 10.

42.

High-sensitivity cardiac troponin concentrations at emergency department presentation in females and males with an acute cardiac outcome.

Kavsak PA, Worster A, Shortt C, Ma J, Clayton N, Sherbino J, Hill SA, McQueen M, Griffith L, Mehta SR, Devereaux PJ.

Ann Clin Biochem. 2018 Sep;55(5):604-607. doi: 10.1177/0004563217743997. Epub 2017 Nov 23.

PMID:
29169258
43.

Association of High-Sensitivity Cardiac Troponin I Concentration With Cardiac Outcomes in Patients With Suspected Acute Coronary Syndrome.

Chapman AR, Lee KK, McAllister DA, Cullen L, Greenslade JH, Parsonage W, Worster A, Kavsak PA, Blankenberg S, Neumann J, Sörensen NA, Westermann D, Buijs MM, Verdel GJE, Pickering JW, Than MP, Twerenbold R, Badertscher P, Sabti Z, Mueller C, Anand A, Adamson P, Strachan FE, Ferry A, Sandeman D, Gray A, Body R, Keevil B, Carlton E, Greaves K, Korley FK, Metkus TS, Sandoval Y, Apple FS, Newby DE, Shah ASV, Mills NL.

JAMA. 2017 Nov 21;318(19):1913-1924. doi: 10.1001/jama.2017.17488. Review. Erratum in: JAMA. 2018 Mar 20;319(11):1168. Soerensen NA [corrected to Sorensen NA].

44.

Comprehensive Age and Sex 99th Percentiles for a High-Sensitivity Cardiac Troponin I Assay.

Estis J, Wu AHB, Todd J, Bishop J, Sandlund J, Kavsak PA.

Clin Chem. 2018 Feb;64(2):398-399. doi: 10.1373/clinchem.2017.276972. Epub 2017 Oct 18. No abstract available.

45.

Analytical comparison of three different versions of a high-sensitivity cardiac troponin I assay over 10years.

Kavsak PA, Worster A, Hill SA, MacRae AR, Jaffe AS.

Clin Chim Acta. 2017 Dec;475:51-55. doi: 10.1016/j.cca.2017.10.006. Epub 2017 Oct 7.

PMID:
29017768
46.

4 hs-cTnI algorithms had high sensitivity and low failure rates for ruling out acute MI in the ED.

Worster A, Kavsak P.

Ann Intern Med. 2017 Sep 19;167(6):JC35. doi: 10.7326/ACPJC-2017-167-6-035. No abstract available.

PMID:
28975325
47.

High-STEACS Algorithm missed fewer patients with acute MI than the ESC Pathway in the ED.

Worster A, Kavsak P.

Ann Intern Med. 2017 Sep 19;167(6):JC34. doi: 10.7326/ACPJC-2017-167-6-034. No abstract available.

PMID:
28975324
48.

Variability and Error in Cardiac Troponin Testing: An ACLPS Critical Review.

Herman DS, Kavsak PA, Greene DN.

Am J Clin Pathol. 2017 Oct 1;148(4):281-295. doi: 10.1093/ajcp/aqx066. Review.

PMID:
28967956
49.

Effect of a low glycemic index diet versus a high-cereal fibre diet on markers of subclinical cardiac injury in healthy individuals with type 2 diabetes mellitus: An exploratory analysis of a randomized dietary trial.

Ha V, Viguiliouk E, Kendall CWC, Balachandran B, Jenkins DJA, Kavsak PA, Sievenpiper JL.

Clin Biochem. 2017 Dec;50(18):1104-1109. doi: 10.1016/j.clinbiochem.2017.09.021. Epub 2017 Sep 25.

PMID:
28958804
50.

Bleeding impacting mortality after noncardiac surgery: a protocol to establish diagnostic criteria, estimate prognostic importance, and develop and validate a prediction guide in an international prospective cohort study.

Roshanov PS, Eikelboom JW, Crowther M, Tandon V, Borges FK, Kearon C, Lamy A, Whitlock R, Biccard BM, Szczeklik W, Guyatt GH, Panju M, Spence J, Garg AX, McGillion M, VanHelder T, Kavsak PA, de Beer J, Winemaker M, Sessler DI, Le Manach Y, Sheth T, Pinthus JH, Thabane L, Simunovic MRI, Mizera R, Ribas S, Devereaux PJ; Vascular Events In Noncardiac Surgery Patients Cohort Evaluation (VISION) Investigators.

CMAJ Open. 2017 Aug 4;5(3):E594-E603. doi: 10.9778/cmajo.20160106.

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