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Items: 45

1.

Structures of respiratory syncytial virus G antigen bound to broadly neutralizing antibodies.

Fedechkin SO, George NL, Wolff JT, Kauvar LM, DuBois RM.

Sci Immunol. 2018 Mar 9;3(21). pii: eaar3534. doi: 10.1126/sciimmunol.aar3534. Epub 2018 Mar 9.

PMID:
29523582
2.

Native Human Monoclonal Antibodies with Potent Cross-Lineage Neutralization of Influenza B Viruses.

Vigil A, Estélles A, Kauvar LM, Johnson SK, Tripp RA, Wittekind M.

Antimicrob Agents Chemother. 2018 Apr 26;62(5). pii: e02269-17. doi: 10.1128/AAC.02269-17. Print 2018 May.

3.

Respiratory Syncytial Virus: Targeting the G Protein Provides a New Approach for an Old Problem.

Tripp RA, Power UF, Openshaw PJM, Kauvar LM.

J Virol. 2018 Jan 17;92(3). pii: e01302-17. doi: 10.1128/JVI.01302-17. Print 2018 Feb 1. Review.

4.

High affinity anti-TIM-3 and anti-KIR monoclonal antibodies cloned from healthy human individuals.

Ryser S, Estellés A, Tenorio E, Kauvar LM, Gishizky ML.

PLoS One. 2017 Jul 19;12(7):e0181464. doi: 10.1371/journal.pone.0181464. eCollection 2017.

5.

A Human Biofilm-Disrupting Monoclonal Antibody Potentiates Antibiotic Efficacy in Rodent Models of both Staphylococcus aureus and Acinetobacter baumannii Infections.

Xiong YQ, Estellés A, Li L, Abdelhady W, Gonzales R, Bayer AS, Tenorio E, Leighton A, Ryser S, Kauvar LM.

Antimicrob Agents Chemother. 2017 Sep 22;61(10). pii: e00904-17. doi: 10.1128/AAC.00904-17. Print 2017 Oct.

6.

Impact of Antibodies and Strain Polymorphisms on Cytomegalovirus Entry and Spread in Fibroblasts and Epithelial Cells.

Cui X, Freed DC, Wang D, Qiu P, Li F, Fu TM, Kauvar LM, McVoy MA.

J Virol. 2017 Jun 9;91(13). pii: e01650-16. doi: 10.1128/JVI.01650-16. Print 2017 Jul 1.

7.

Maternal Antibody Responses and Nonprimary Congenital Cytomegalovirus Infection of HIV-1-Exposed Infants.

Bialas KM, Westreich D, Cisneros de la Rosa E, Nelson CS, Kauvar LM, Fu TM, Permar SR.

J Infect Dis. 2016 Dec 15;214(12):1916-1923. Epub 2016 Oct 20.

8.

A High-Affinity Native Human Antibody Disrupts Biofilm from Staphylococcus aureus Bacteria and Potentiates Antibiotic Efficacy in a Mouse Implant Infection Model.

Estellés A, Woischnig AK, Liu K, Stephenson R, Lomongsod E, Nguyen D, Zhang J, Heidecker M, Yang Y, Simon RJ, Tenorio E, Ellsworth S, Leighton A, Ryser S, Gremmelmaier NK, Kauvar LM.

Antimicrob Agents Chemother. 2016 Mar 25;60(4):2292-301. doi: 10.1128/AAC.02588-15. Print 2016 Apr.

9.

Human cytomegalovirus infection interferes with the maintenance and differentiation of trophoblast progenitor cells of the human placenta.

Tabata T, Petitt M, Zydek M, Fang-Hoover J, Larocque N, Tsuge M, Gormley M, Kauvar LM, Pereira L.

J Virol. 2015 May;89(9):5134-47. doi: 10.1128/JVI.03674-14. Epub 2015 Mar 4.

10.

A high-affinity native human antibody neutralizes human cytomegalovirus infection of diverse cell types.

Kauvar LM, Liu K, Park M, DeChene N, Stephenson R, Tenorio E, Ellsworth SL, Tabata T, Petitt M, Tsuge M, Fang-Hoover J, Adler SP, Cui X, McVoy MA, Pereira L.

Antimicrob Agents Chemother. 2015 Mar;59(3):1558-68. doi: 10.1128/AAC.04295-14. Epub 2014 Dec 22.

11.

HCMV infection of human trophoblast progenitor cells of the placenta is neutralized by a human monoclonal antibody to glycoprotein B and not by antibodies to the pentamer complex.

Zydek M, Petitt M, Fang-Hoover J, Adler B, Kauvar LM, Pereira L, Tabata T.

Viruses. 2014 Mar 19;6(3):1346-64. doi: 10.3390/v6031346.

12.

Multiplexed screening of natural humoral immunity identifies antibodies at fine specificity for complex and dynamic viral targets.

McCutcheon KM, Gray J, Chen NY, Liu K, Park M, Ellsworth S, Tripp RA, Tompkins SM, Johnson SK, Samet S, Pereira L, Kauvar LM.

MAbs. 2014 Mar-Apr;6(2):460-73. doi: 10.4161/mabs.27760. Epub 2014 Jan 8.

13.

Intrauterine growth restriction caused by underlying congenital cytomegalovirus infection.

Pereira L, Petitt M, Fong A, Tsuge M, Tabata T, Fang-Hoover J, Maidji E, Zydek M, Zhou Y, Inoue N, Loghavi S, Pepkowitz S, Kauvar LM, Ogunyemi D.

J Infect Dis. 2014 May 15;209(10):1573-84. doi: 10.1093/infdis/jiu019. Epub 2014 Jan 7.

14.

Therapeutic targeting of respiratory syncytial virus G-protein.

Kauvar LM, Harcourt JL, Haynes LM, Tripp RA.

Immunotherapy. 2010 Sep;2(5):655-61. doi: 10.2217/imt.10.53. Review.

15.

Potent high-affinity antibodies for treatment and prophylaxis of respiratory syncytial virus derived from B cells of infected patients.

Collarini EJ, Lee FE, Foord O, Park M, Sperinde G, Wu H, Harriman WD, Carroll SF, Ellsworth SL, Anderson LJ, Tripp RA, Walsh EE, Keyt BA, Kauvar LM.

J Immunol. 2009 Nov 15;183(10):6338-45. doi: 10.4049/jimmunol.0901373. Epub 2009 Oct 19.

16.

A serum amyloid P-binding hydrogel speeds healing of partial thickness wounds in pigs.

Gomer RH, Pilling D, Kauvar LM, Ellsworth S, Ronkainen SD, Roife D, Davis SC.

Wound Repair Regen. 2009 May-Jun;17(3):397-404. doi: 10.1111/j.1524-475X.2009.00482.x.

17.

Antibody discovery via multiplexed single cell characterization.

Harriman WD, Collarini EJ, Sperinde GV, Strandh M, Fatholahi MM, Dutta A, Lee Y, Mettler SE, Keyt BA, Ellsworth SL, Kauvar LM.

J Immunol Methods. 2009 Feb 28;341(1-2):135-45. doi: 10.1016/j.jim.2008.11.009. Epub 2008 Dec 16.

18.

Multiplexed Elispot assay.

Harriman WD, Collarini EJ, Cromer RG, Dutta A, Strandh M, Zhang F, Kauvar LM.

J Immunol Methods. 2009 Feb 28;341(1-2):127-34. doi: 10.1016/j.jim.2008.11.010. Epub 2008 Dec 11.

19.

Pharmacological regulation of network kinetics by protein kinase C localization.

Mochly-Rosen D, Kauvar LM.

Semin Immunol. 2000 Feb;12(1):55-61. Review.

PMID:
10723798
20.

Direct interaction in T-cells between thetaPKC and the tyrosine kinase p59fyn.

Ron D, Napolitano EW, Voronova A, Vasquez NJ, Roberts DN, Calio BL, Caothien RH, Pettiford SM, Wellik S, Mandac JB, Kauvar LM.

J Biol Chem. 1999 Jul 2;274(27):19003-10.

21.

Protein affinity map of chemical space.

Kauvar LM, Villar HO, Sportsman JR, Higgins DL, Schmidt DE Jr.

J Chromatogr B Biomed Sci Appl. 1998 Sep 11;715(1):93-102.

PMID:
9792501
22.

Deciphering cryptic similarities in protein binding sites.

Kauvar LM, Villar HO.

Curr Opin Biotechnol. 1998 Aug;9(4):390-394.

PMID:
9751636
23.

Glutathione based approaches to improving cancer treatment.

Kauvar LM, Morgan AS, Sanderson PE, Henner WD.

Chem Biol Interact. 1998 Apr 24;111-112:225-38. Review.

PMID:
9679557
24.

Tumor efficacy and bone marrow-sparing properties of TER286, a cytotoxin activated by glutathione S-transferase.

Morgan AS, Sanderson PE, Borch RF, Tew KD, Niitsu Y, Takayama T, Von Hoff DD, Izbicka E, Mangold G, Paul C, Broberg U, Mannervik B, Henner WD, Kauvar LM.

Cancer Res. 1998 Jun 15;58(12):2568-75.

25.

The diversity challenge in combinatorial chemistry.

Kauvar LM, Laborde E.

Curr Opin Drug Discov Devel. 1998 Jul;1(1):66-70. No abstract available.

PMID:
19649791
26.

Modulating protein kinase C signal transduction.

Mochly-Rosen D, Kauvar LM.

Adv Pharmacol. 1998;44:91-145. Review. No abstract available.

PMID:
9547885
27.

Peptide mimetic drugs: a comment on progress and prospects.

Kauvar LM.

Nat Biotechnol. 1996 Jun;14(6):709. No abstract available.

PMID:
9630974
28.

Glubodies: randomized libraries of glutathione transferase enzymes.

Napolitano EW, Villar HO, Kauvar LM, Higgins DL, Roberts D, Mandac J, Lee SK, Engqvist-Goldstein A, Bukar R, Calio BL, Jäck HM, Tainer JA.

Chem Biol. 1996 May;3(5):359-67.

29.

Isozyme-specific glutathione S-transferase inhibitors potentiate drug sensitivity in cultured human tumor cell lines.

Morgan AS, Ciaccio PJ, Tew KD, Kauvar LM.

Cancer Chemother Pharmacol. 1996;37(4):363-70.

PMID:
8548883
30.

Affinity fingerprinting.

Kauvar LM.

Biotechnology (N Y). 1995 Sep;13(9):965-6. No abstract available.

PMID:
9678954
31.

Mutagenesis using trinucleotide beta-cyanoethyl phosphoramidites.

Lyttle MH, Napolitano EW, Calio BL, Kauvar LM.

Biotechniques. 1995 Aug;19(2):274-81.

PMID:
8527149
32.

Predicting ligand binding to proteins by affinity fingerprinting.

Kauvar LM, Higgins DL, Villar HO, Sportsman JR, Engqvist-Goldstein A, Bukar R, Bauer KE, Dilley H, Rocke DM.

Chem Biol. 1995 Feb;2(2):107-18.

33.

Variability of glutathione S-transferase isoenzyme patterns in matched normal and cancer human breast tissue.

Kelley MK, Engqvist-Goldstein A, Montali JA, Wheatley JB, Schmidt DE Jr, Kauvar LM.

Biochem J. 1994 Dec 15;304 ( Pt 3):843-8.

34.

Amino acid preferences at protein binding sites.

Villar HO, Kauvar LM.

FEBS Lett. 1994 Jul 25;349(1):125-30.

35.

Glutathione-S-transferase activates novel alkylating agents.

Lyttle MH, Satyam A, Hocker MD, Bauer KE, Caldwell CG, Hui HC, Morgan AS, Mergia A, Kauvar LM.

J Med Chem. 1994 May 13;37(10):1501-7.

PMID:
8182709
36.

Glutathione analogue sorbents selectively bind glutathione S-transferase isoenzymes.

Castro VM, Kelley MK, Engqvist-Goldstein A, Kauvar LM.

Biochem J. 1993 Jun 1;292 ( Pt 2):371-7.

37.

Spin dialysis desalting of small protein samples in a membrane-bottomed 96-well microplate.

Berry CO, Kauvar LM.

Biotechniques. 1993 Mar;14(3):340. No abstract available.

PMID:
8457334
38.

Isozyme specificity of novel glutathione-S-transferase inhibitors.

Flatgaard JE, Bauer KE, Kauvar LM.

Cancer Chemother Pharmacol. 1993;33(1):63-70.

PMID:
8269591
39.

"Paralogs", sorbent families for protein separations.

Benedek K, Várkonyi A, Hughes B, Zabel K, Kauvar LM.

J Chromatogr. 1992 Dec 25;627(1-2):51-61.

PMID:
1487530
40.

Paralog chromatography.

Kauvar LM, Cheung PY, Gomer RH, Fleischer AA.

Biotechniques. 1990 Feb;8(2):204-9.

PMID:
2317377
41.

The engrailed locus of Drosophila melanogaster: genetic, developmental, and molecular studies.

Ali Z, Drees B, Coleman KG, Gustavson E, Karr TL, Kauvar LM, Poole SJ, Soeller W, Weir MP, Kornberg T.

Cold Spring Harb Symp Quant Biol. 1985;50:229-33. No abstract available.

PMID:
3938362
42.

The engrailed locus of Drosophila: structural analysis of an embryonic transcript.

Poole SJ, Kauvar LM, Drees B, Kornberg T.

Cell. 1985 Jan;40(1):37-43.

PMID:
3917855
43.

Drosophila cyclic nucleotide phosphodiesterases.

Davis RL, Kauvar LM.

Adv Cyclic Nucleotide Protein Phosphorylation Res. 1984;16:393-402. No abstract available.

PMID:
6326533
45.

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