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Items: 29


Circulating Picomolar Levels of CCL2 Downregulate Ongoing Chronic Experimental Autoimmune Encephalomyelitis by Induction of Regulatory Mechanisms.

Kaushansky N, Bakos E, Becker-Herman S, Shachar I, Ben-Nun A.

J Immunol. 2019 Oct 1;203(7):1857-1866. doi: 10.4049/jimmunol.1900424. Epub 2019 Sep 4.


Modulation of MS-like disease by a multi epitope protein is mediated by induction of CD11c+CD11b+Gr1+ myeloid-derived dendritic cells.

Kaushansky N, Kaminitz A, Allouche-Arnon H, Ben-Nun A.

J Neuroimmunol. 2019 Aug 15;333:476953. doi: 10.1016/j.jneuroim.2019.04.013. Epub 2019 May 9.


Daily Onset of Light and Darkness Differentially Controls Hematopoietic Stem Cell Differentiation and Maintenance.

Golan K, Kumari A, Kollet O, Khatib-Massalha E, Subramaniam MD, Ferreira ZS, Avemaria F, Rzeszotek S, García-García A, Xie S, Flores-Figueroa E, Gur-Cohen S, Itkin T, Ludin-Tal A, Massalha H, Bernshtein B, Ciechanowicz AK, Brandis A, Mehlman T, Bhattacharya S, Bertagna M, Cheng H, Petrovich-Kopitman E, Janus T, Kaushansky N, Cheng T, Sagi I, Ratajczak MZ, Méndez-Ferrer S, Dick JE, Markus RP, Lapidot T.

Cell Stem Cell. 2018 Oct 4;23(4):572-585.e7. doi: 10.1016/j.stem.2018.08.002. Epub 2018 Aug 30.


Small Molecules Co-targeting CKIα and the Transcriptional Kinases CDK7/9 Control AML in Preclinical Models.

Minzel W, Venkatachalam A, Fink A, Hung E, Brachya G, Burstain I, Shaham M, Rivlin A, Omer I, Zinger A, Elias S, Winter E, Erdman PE, Sullivan RW, Fung L, Mercurio F, Li D, Vacca J, Kaushansky N, Shlush L, Oren M, Levine R, Pikarsky E, Snir-Alkalay I, Ben-Neriah Y.

Cell. 2018 Sep 20;175(1):171-185.e25. doi: 10.1016/j.cell.2018.07.045. Epub 2018 Aug 23.


Inhomogeneous Encoding of the Visual Field in the Mouse Retina.

Warwick RA, Kaushansky N, Sarid N, Golan A, Rivlin-Etzion M.

Curr Biol. 2018 Mar 5;28(5):655-665.e3. doi: 10.1016/j.cub.2018.01.016. Epub 2018 Feb 15.


CCR2 Regulates the Immune Response by Modulating the Interconversion and Function of Effector and Regulatory T Cells.

Bakos E, Thaiss CA, Kramer MP, Cohen S, Radomir L, Orr I, Kaushansky N, Ben-Nun A, Becker-Herman S, Shachar I.

J Immunol. 2017 Jun 15;198(12):4659-4671. doi: 10.4049/jimmunol.1601458. Epub 2017 May 15.


Pathways and gene networks mediating the regulatory effects of cannabidiol, a nonpsychoactive cannabinoid, in autoimmune T cells.

Kozela E, Juknat A, Gao F, Kaushansky N, Coppola G, Vogel Z.

J Neuroinflammation. 2016 Jun 3;13(1):136. doi: 10.1186/s12974-016-0603-x.


Post-CNS-inflammation expression of CXCL12 promotes the endogenous myelin/neuronal repair capacity following spontaneous recovery from multiple sclerosis-like disease.

Zilkha-Falb R, Kaushansky N, Kawakami N, Ben-Nun A.

J Neuroinflammation. 2016 Jan 8;13:7. doi: 10.1186/s12974-015-0468-4.


Anti-inflammatory effects of the cannabidiol derivative dimethylheptyl-cannabidiol - studies in BV-2 microglia and encephalitogenic T cells.

Juknat A, Kozela E, Kaushansky N, Mechoulam R, Vogel Z.

J Basic Clin Physiol Pharmacol. 2016 May 1;27(3):289-96. doi: 10.1515/jbcpp-2015-0071.


CD151 Regulates T-Cell Migration in Health and Inflammatory Bowel Disease.

Zelman-Toister E, Bakos E, Cohen S, Zigmond E, Shezen E, Grabovsky V, Sagiv A, Hart G, Kaushansky N, Ben-Nun A, Maharshak N, Sonnenberg A, Alon R, Becker-Herman S, Shachar I.

Inflamm Bowel Dis. 2016 Feb;22(2):257-67. doi: 10.1097/MIB.0000000000000621.


HU-446 and HU-465, Derivatives of the Non-psychoactive Cannabinoid Cannabidiol, Decrease the Activation of Encephalitogenic T Cells.

Kozela E, Haj C, Hanuš L, Chourasia M, Shurki A, Juknat A, Kaushansky N, Mechoulam R, Vogel Z.

Chem Biol Drug Des. 2016 Jan;87(1):143-53. doi: 10.1111/cbdd.12637. Epub 2015 Sep 16.


Role of a Novel Human Leukocyte Antigen-DQA1*01:02;DRB1*15:01 Mixed Isotype Heterodimer in the Pathogenesis of "Humanized" Multiple Sclerosis-like Disease.

Kaushansky N, Eisenstein M, Boura-Halfon S, Hansen BE, Nielsen CH, Milo R, Zeilig G, Lassmann H, Altmann DM, Ben-Nun A.

J Biol Chem. 2015 Jun 12;290(24):15260-78. doi: 10.1074/jbc.M115.641209. Epub 2015 Apr 24.


Cannabidiol, a non-psychoactive cannabinoid, leads to EGR2-dependent anergy in activated encephalitogenic T cells.

Kozela E, Juknat A, Kaushansky N, Ben-Nun A, Coppola G, Vogel Z.

J Neuroinflammation. 2015 Mar 15;12:52. doi: 10.1186/s12974-015-0273-0.


From classic to spontaneous and humanized models of multiple sclerosis: impact on understanding pathogenesis and drug development.

Ben-Nun A, Kaushansky N, Kawakami N, Krishnamoorthy G, Berer K, Liblau R, Hohlfeld R, Wekerle H.

J Autoimmun. 2014 Nov;54:33-50. doi: 10.1016/j.jaut.2014.06.004. Epub 2014 Aug 28. Review.


An immunomodulating motif of the HIV-1 fusion protein is chirality-independent: implications for its mode of action.

Faingold O, Ashkenazi A, Kaushansky N, Ben-Nun A, Shai Y.

J Biol Chem. 2013 Nov 15;288(46):32852-60. doi: 10.1074/jbc.M113.512038. Epub 2013 Sep 27.


Cannabinoids decrease the th17 inflammatory autoimmune phenotype.

Kozela E, Juknat A, Kaushansky N, Rimmerman N, Ben-Nun A, Vogel Z.

J Neuroimmune Pharmacol. 2013 Dec;8(5):1265-76. doi: 10.1007/s11481-013-9493-1. Epub 2013 Jul 28.


A highly conserved sequence associated with the HIV gp41 loop region is an immunomodulator of antigen-specific T cells in mice.

Ashkenazi A, Faingold O, Kaushansky N, Ben-Nun A, Shai Y.

Blood. 2013 Mar 21;121(12):2244-52. doi: 10.1182/blood-2012-11-468900. Epub 2013 Jan 16.


DQB1*0602 rather than DRB1*1501 confers susceptibility to multiple sclerosis-like disease induced by proteolipid protein (PLP).

Kaushansky N, Altmann DM, David CS, Lassmann H, Ben-Nun A.

J Neuroinflammation. 2012 Feb 8;9:29. doi: 10.1186/1742-2094-9-29.


'Multi-epitope-targeted' immune-specific therapy for a multiple sclerosis-like disease via engineered multi-epitope protein is superior to peptides.

Kaushansky N, Kerlero de Rosbo N, Zilkha-Falb R, Yosef-Hemo R, Cohen L, Ben-Nun A.

PLoS One. 2011;6(11):e27860. doi: 10.1371/journal.pone.0027860. Epub 2011 Nov 29.


Cannabidiol inhibits pathogenic T cells, decreases spinal microglial activation and ameliorates multiple sclerosis-like disease in C57BL/6 mice.

Kozela E, Lev N, Kaushansky N, Eilam R, Rimmerman N, Levy R, Ben-Nun A, Juknat A, Vogel Z.

Br J Pharmacol. 2011 Aug;163(7):1507-19. doi: 10.1111/j.1476-5381.2011.01379.x.


The myelin-associated oligodendrocytic basic protein (MOBP) as a relevant primary target autoantigen in multiple sclerosis.

Kaushansky N, Eisenstein M, Zilkha-Falb R, Ben-Nun A.

Autoimmun Rev. 2010 Feb;9(4):233-6. doi: 10.1016/j.autrev.2009.08.002. Epub 2009 Aug 13. Review.


HLA-DQB1*0602 determines disease susceptibility in a new "humanized" multiple sclerosis model in HLA-DR15 (DRB1*1501;DQB1*0602) transgenic mice.

Kaushansky N, Altmann DM, Ascough S, David CS, Lassmann H, Ben-Nun A.

J Immunol. 2009 Sep 1;183(5):3531-41. doi: 10.4049/jimmunol.0900784. Epub 2009 Jul 31.


Activation and control of pathogenic T cells in OSP/claudin-11-induced EAE in SJL/J mice are dominated by their focused recognition of a single epitopic residue (OSP58M).

Kaushansky N, Eisenstein M, Oved JH, Ben-Nun A.

Int Immunol. 2008 Nov;20(11):1439-49. doi: 10.1093/intimm/dxn099. Epub 2008 Sep 18.


Pathogenic T cells in MOBP-induced murine EAE are predominantly focused to recognition of MOBP21F and MOBP27P epitopic residues.

Kaushansky N, Zilkha-Falb R, Hemo R, Lassman H, Eisenstein M, Sas A, Ben-Nun A.

Eur J Immunol. 2007 Nov;37(11):3281-92.


Anatomy of T cell autoimmunity to myelin oligodendrocyte glycoprotein (MOG): prime role of MOG44F in selection and control of MOG-reactive T cells in H-2b mice.

Ben-Nun A, Kerlero de Rosbo N, Kaushansky N, Eisenstein M, Cohen L, Kaye JF, Mendel I.

Eur J Immunol. 2006 Feb;36(2):478-93.


Acoustic and optical transduction of BuChE binding to procainamide modified surfaces.

Marx S, Kaushansky N, Gratziany N, Barness I, Liron Z.

Biosens Bioelectron. 2001 Jun;16(4-5):239-44.


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