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Items: 1 to 50 of 142

1.

Synergistic activation of CatSper Ca2+ channels in human sperm by oviductal ligands and endocrine disrupting chemicals.

Brenker C, Rehfeld A, Schiffer C, Kierzek M, Kaupp UB, Skakkebæk NE, Strünker T.

Hum Reprod. 2018 Oct 1;33(10):1915-1923. doi: 10.1093/humrep/dey275.

PMID:
30189007
2.

The solute carrier SLC9C1 is a Na+/H+-exchanger gated by an S4-type voltage-sensor and cyclic-nucleotide binding.

Windler F, Bönigk W, Körschen HG, Grahn E, Strünker T, Seifert R, Kaupp UB.

Nat Commun. 2018 Jul 18;9(1):2809. doi: 10.1038/s41467-018-05253-x.

3.

Action of steroids and plant triterpenoids on CatSper Ca2+ channels in human sperm.

Brenker C, Schiffer C, Wagner IV, Tüttelmann F, Röpke A, Rennhack A, Kaupp UB, Strünker T.

Proc Natl Acad Sci U S A. 2018 Jan 16;115(3):E344-E346. doi: 10.1073/pnas.1717929115. Epub 2018 Jan 5. No abstract available.

4.

Human sperm steer with second harmonics of the flagellar beat.

Saggiorato G, Alvarez L, Jikeli JF, Kaupp UB, Gompper G, Elgeti J.

Nat Commun. 2017 Nov 10;8(1):1415. doi: 10.1038/s41467-017-01462-y.

5.

Photocontrol of the Hv1 Proton Channel.

Rennhack A, Grahn E, Kaupp UB, Berger TK.

ACS Chem Biol. 2017 Dec 15;12(12):2952-2957. doi: 10.1021/acschembio.7b00523. Epub 2017 Nov 7.

PMID:
29024582
6.

Sperm Sensory Signaling.

Wachten D, Jikeli JF, Kaupp UB.

Cold Spring Harb Perspect Biol. 2017 Jul 5;9(7). pii: a028225. doi: 10.1101/cshperspect.a028225. Review.

PMID:
28062561
7.

Post-translational cleavage of Hv1 in human sperm tunes pH- and voltage-dependent gating.

Berger TK, Fußhöller DM, Goodwin N, Bönigk W, Müller A, Dokani Khesroshahi N, Brenker C, Wachten D, Krause E, Kaupp UB, Strünker T.

J Physiol. 2017 Mar 1;595(5):1533-1546. doi: 10.1113/JP273189. Epub 2017 Jan 15.

8.

Signaling in Sperm: More Different than Similar.

Kaupp UB, Strünker T.

Trends Cell Biol. 2017 Feb;27(2):101-109. doi: 10.1016/j.tcb.2016.10.002. Epub 2016 Nov 5. Review.

PMID:
27825709
9.

A Quantitative Model for cAMP Binding to the Binding Domain of MloK1.

Voß B, Seifert R, Kaupp UB, Grubmüller H.

Biophys J. 2016 Oct 18;111(8):1668-1678. doi: 10.1016/j.bpj.2016.09.014.

10.

A novel biosensor to study cAMP dynamics in cilia and flagella.

Mukherjee S, Jansen V, Jikeli JF, Hamzeh H, Alvarez L, Dombrowski M, Balbach M, Strünker T, Seifert R, Kaupp UB, Wachten D.

Elife. 2016 Mar 22;5. pii: e14052. doi: 10.7554/eLife.14052.

11.

A K(+)-selective CNG channel orchestrates Ca(2+) signalling in zebrafish sperm.

Fechner S, Alvarez L, Bönigk W, Müller A, Berger TK, Pascal R, Trötschel C, Poetsch A, Stölting G, Siegfried KR, Kremmer E, Seifert R, Kaupp UB.

Elife. 2015 Dec 9;4. pii: e07624. doi: 10.7554/eLife.07624.

12.

Downregulation of Spermine Augments Dendritic Persistent Sodium Currents and Synaptic Integration after Status Epilepticus.

Royeck M, Kelly T, Opitz T, Otte DM, Rennhack A, Woitecki A, Pitsch J, Becker A, Schoch S, Kaupp UB, Yaari Y, Zimmer A, Beck H.

J Neurosci. 2015 Nov 18;35(46):15240-53. doi: 10.1523/JNEUROSCI.0493-15.2015.

13.

Sperm navigation along helical paths in 3D chemoattractant landscapes.

Jikeli JF, Alvarez L, Friedrich BM, Wilson LG, Pascal R, Colin R, Pichlo M, Rennhack A, Brenker C, Kaupp UB.

Nat Commun. 2015 Aug 17;6:7985. doi: 10.1038/ncomms8985.

14.

Larry Cohen-50 ways to DYE your science.

Strünker T, Kaupp UB.

Neurophotonics. 2015 Apr;2(2):021004. doi: 10.1117/1.NPh.2.2.021004. No abstract available.

15.

At the physical limit - chemosensation in sperm.

Strünker T, Alvarez L, Kaupp UB.

Curr Opin Neurobiol. 2015 Oct;34:110-6. doi: 10.1016/j.conb.2015.02.007. Epub 2015 Mar 11. Review.

PMID:
25768273
16.

Higher-order architecture of rhodopsin in intact photoreceptors and its implication for phototransduction kinetics.

Gunkel M, Schöneberg J, Alkhaldi W, Irsen S, Noé F, Kaupp UB, Al-Amoudi A.

Structure. 2015 Apr 7;23(4):628-38. doi: 10.1016/j.str.2015.01.015. Epub 2015 Feb 26.

17.

Controlling fertilization and cAMP signaling in sperm by optogenetics.

Jansen V, Alvarez L, Balbach M, Strünker T, Hegemann P, Kaupp UB, Wachten D.

Elife. 2015 Jan 20;4. doi: 10.7554/eLife.05161.

18.

The CatSper channel controls chemosensation in sea urchin sperm.

Seifert R, Flick M, Bönigk W, Alvarez L, Trötschel C, Poetsch A, Müller A, Goodwin N, Pelzer P, Kashikar ND, Kremmer E, Jikeli J, Timmermann B, Kuhl H, Fridman D, Windler F, Kaupp UB, Strünker T.

EMBO J. 2015 Feb 3;34(3):379-92. doi: 10.15252/embj.201489376. Epub 2014 Dec 22.

19.

Resonance assignment of the ligand-free cyclic nucleotide-binding domain from the murine ion channel HCN2.

Börger C, Schünke S, Lecher J, Stoldt M, Winkhaus F, Kaupp UB, Willbold D.

Biomol NMR Assign. 2015 Oct;9(2):243-6. doi: 10.1007/s12104-014-9583-x. Epub 2014 Oct 17.

PMID:
25324217
20.

High density and ligand affinity confer ultrasensitive signal detection by a guanylyl cyclase chemoreceptor.

Pichlo M, Bungert-Plümke S, Weyand I, Seifert R, Bönigk W, Strünker T, Kashikar ND, Goodwin N, Müller A, Pelzer P, Van Q, Enderlein J, Klemm C, Krause E, Trötschel C, Poetsch A, Kremmer E, Kaupp UB, Körschen HG, Collienne U.

J Cell Biol. 2014 Aug 18;206(4):541-57. doi: 10.1083/jcb.201402027. Erratum in: J Cell Biol. 2014 Dec 8;207(5):675. Körschen, Heinz G [Added] and Collienne, Ursel [Added].

21.

Direct action of endocrine disrupting chemicals on human sperm.

Schiffer C, Müller A, Egeberg DL, Alvarez L, Brenker C, Rehfeld A, Frederiksen H, Wäschle B, Kaupp UB, Balbach M, Wachten D, Skakkebaek NE, Almstrup K, Strünker T.

EMBO Rep. 2014 Jul;15(7):758-65. doi: 10.15252/embr.201438869. Epub 2014 May 12.

22.

The Ca2+-activated K+ current of human sperm is mediated by Slo3.

Brenker C, Zhou Y, Müller A, Echeverry FA, Trötschel C, Poetsch A, Xia XM, Bönigk W, Lingle CJ, Kaupp UB, Strünker T.

Elife. 2014 Mar 26;3:e01438. doi: 10.7554/eLife.01438.

23.

The computational sperm cell.

Alvarez L, Friedrich BM, Gompper G, Kaupp UB.

Trends Cell Biol. 2014 Mar;24(3):198-207. doi: 10.1016/j.tcb.2013.10.004. Epub 2013 Dec 14. Review.

PMID:
24342435
24.

CRIS-a novel cAMP-binding protein controlling spermiogenesis and the development of flagellar bending.

Krähling AM, Alvarez L, Debowski K, Van Q, Gunkel M, Irsen S, Al-Amoudi A, Strünker T, Kremmer E, Krause E, Voigt I, Wörtge S, Waisman A, Weyand I, Seifert R, Kaupp UB, Wachten D.

PLoS Genet. 2013;9(12):e1003960. doi: 10.1371/journal.pgen.1003960. Epub 2013 Dec 5.

25.

Regulation of Son of sevenless by the membrane-actin linker protein ezrin.

Geissler KJ, Jung MJ, Riecken LB, Sperka T, Cui Y, Schacke S, Merkel U, Markwart R, Rubio I, Than ME, Breithaupt C, Peuker S, Seifert R, Kaupp UB, Herrlich P, Morrison H.

Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):20587-92. doi: 10.1073/pnas.1222078110. Epub 2013 Dec 2.

26.

Sperm from sneaker male squids exhibit chemotactic swarming to CO₂.

Hirohashi N, Alvarez L, Shiba K, Fujiwara E, Iwata Y, Mohri T, Inaba K, Chiba K, Ochi H, Supuran CT, Kotzur N, Kakiuchi Y, Kaupp UB, Baba SA.

Curr Biol. 2013 May 6;23(9):775-81. doi: 10.1016/j.cub.2013.03.040. Epub 2013 Apr 11.

27.

Kinetics of ligand-receptor interaction reveals an induced-fit mode of binding in a cyclic nucleotide-activated protein.

Peuker S, Cukkemane A, Held M, Noé F, Kaupp UB, Seifert R.

Biophys J. 2013 Jan 8;104(1):63-74. doi: 10.1016/j.bpj.2012.11.3816. Epub 2013 Jan 8.

28.

The non-lysosomal β-glucosidase GBA2 is a non-integral membrane-associated protein at the endoplasmic reticulum (ER) and Golgi.

Körschen HG, Yildiz Y, Raju DN, Schonauer S, Bönigk W, Jansen V, Kremmer E, Kaupp UB, Wachten D.

J Biol Chem. 2013 Feb 1;288(5):3381-93. doi: 10.1074/jbc.M112.414714. Epub 2012 Dec 17.

29.

100 years of sperm chemotaxis.

Kaupp UB.

J Gen Physiol. 2012 Dec;140(6):583-6. doi: 10.1085/jgp.201210902. No abstract available.

30.

Temporal sampling, resetting, and adaptation orchestrate gradient sensing in sperm.

Kashikar ND, Alvarez L, Seifert R, Gregor I, Jäckle O, Beyermann M, Krause E, Kaupp UB.

J Cell Biol. 2012 Sep 17;198(6):1075-91. doi: 10.1083/jcb.201204024.

31.

The rate of change in Ca(2+) concentration controls sperm chemotaxis.

Alvarez L, Dai L, Friedrich BM, Kashikar ND, Gregor I, Pascal R, Kaupp UB.

J Cell Biol. 2012 Mar 5;196(5):653-63. doi: 10.1083/jcb.201106096. Epub 2012 Feb 27.

32.

The CatSper channel: a polymodal chemosensor in human sperm.

Brenker C, Goodwin N, Weyand I, Kashikar ND, Naruse M, Krähling M, Müller A, Kaupp UB, Strünker T.

EMBO J. 2012 Apr 4;31(7):1654-65. doi: 10.1038/emboj.2012.30. Epub 2012 Feb 21.

33.

Solid-state NMR [13C,15N] resonance assignments of the nucleotide-binding domain of a bacterial cyclic nucleotide-gated channel.

Cukkemane A, Nand D, Gradmann S, Weingarth M, Kaupp UB, Baldus M.

Biomol NMR Assign. 2012 Oct;6(2):225-9.

34.

Structural insights into conformational changes of a cyclic nucleotide-binding domain in solution from Mesorhizobium loti K1 channel.

Schünke S, Stoldt M, Lecher J, Kaupp UB, Willbold D.

Proc Natl Acad Sci U S A. 2011 Apr 12;108(15):6121-6. doi: 10.1073/pnas.1015890108. Epub 2011 Mar 23.

35.

The CatSper channel mediates progesterone-induced Ca2+ influx in human sperm.

Strünker T, Goodwin N, Brenker C, Kashikar ND, Weyand I, Seifert R, Kaupp UB.

Nature. 2011 Mar 17;471(7338):382-6. doi: 10.1038/nature09769.

PMID:
21412338
36.

Cooperative and uncooperative cyclic-nucleotide-gated ion channels.

Cukkemane A, Seifert R, Kaupp UB.

Trends Biochem Sci. 2011 Jan;36(1):55-64. doi: 10.1016/j.tibs.2010.07.004. Epub 2010 Aug 21. Review.

PMID:
20729090
37.

Hydrodynamics of sperm cells near surfaces.

Elgeti J, Kaupp UB, Gompper G.

Biophys J. 2010 Aug 9;99(4):1018-26. doi: 10.1016/j.bpj.2010.05.015.

38.

Resonance assignments of the nucleotide-free wildtype MloK1 cyclic nucleotide-binding domain.

Schünke S, Lecher J, Stoldt M, Kaupp UB, Willbold D.

Biomol NMR Assign. 2010 Oct;4(2):147-50. doi: 10.1007/s12104-010-9231-z. Epub 2010 May 7.

PMID:
20449776
39.

Olfactory signalling in vertebrates and insects: differences and commonalities.

Kaupp UB.

Nat Rev Neurosci. 2010 Mar;11(3):188-200. doi: 10.1038/nrn2789. Epub 2010 Feb 10. Review.

PMID:
20145624
40.

Hyperpolarization-activated and cyclic nucleotide-gated channels are differentially expressed in juxtaglomerular cells in the olfactory bulb of mice.

Fried HU, Kaupp UB, Müller F.

Cell Tissue Res. 2010 Mar;339(3):463-79. doi: 10.1007/s00441-009-0904-9. Epub 2010 Feb 6.

41.

An atypical CNG channel activated by a single cGMP molecule controls sperm chemotaxis.

Bönigk W, Loogen A, Seifert R, Kashikar N, Klemm C, Krause E, Hagen V, Kremmer E, Strünker T, Kaupp UB.

Sci Signal. 2009 Oct 27;2(94):ra68. doi: 10.1126/scisignal.2000516.

42.

Solution structure of the Mesorhizobium loti K1 channel cyclic nucleotide-binding domain in complex with cAMP.

Schünke S, Stoldt M, Novak K, Kaupp UB, Willbold D.

EMBO Rep. 2009 Jul;10(7):729-35. doi: 10.1038/embor.2009.68. Epub 2009 May 22.

43.

Caged progesterone: a new tool for studying rapid nongenomic actions of progesterone.

Kilic F, Kashikar ND, Schmidt R, Alvarez L, Dai L, Weyand I, Wiesner B, Goodwin N, Hagen V, Kaupp UB.

J Am Chem Soc. 2009 Mar 25;131(11):4027-30. doi: 10.1021/ja808334f.

PMID:
19256499
44.

Light responses in the mouse retina are prolonged upon targeted deletion of the HCN1 channel gene.

Knop GC, Seeliger MW, Thiel F, Mataruga A, Kaupp UB, Friedburg C, Tanimoto N, Müller F.

Eur J Neurosci. 2008 Dec;28(11):2221-30. doi: 10.1111/j.1460-9568.2008.06512.x. Epub 2008 Nov 3.

PMID:
19019198
45.

Cardiac pacemaker function of HCN4 channels in mice is confined to embryonic development and requires cyclic AMP.

Harzheim D, Pfeiffer KH, Fabritz L, Kremmer E, Buch T, Waisman A, Kirchhof P, Kaupp UB, Seifert R.

EMBO J. 2008 Feb 20;27(4):692-703. doi: 10.1038/emboj.2008.3. Epub 2008 Jan 24.

46.

Resonance assignment of the cyclic nucleotide binding domain from a cyclic nucleotide-gated K(+) channel in complex with cAMP.

Schünke S, Novak K, Stoldt M, Kaupp UB, Willbold D.

Biomol NMR Assign. 2007 Dec;1(2):179-81. doi: 10.1007/s12104-007-9049-5. Epub 2007 Sep 8.

PMID:
19636859
47.

Mechanisms of sperm chemotaxis.

Kaupp UB, Kashikar ND, Weyand I.

Annu Rev Physiol. 2008;70:93-117. Review.

PMID:
17988206
48.

Subunits act independently in a cyclic nucleotide-activated K(+) channel.

Cukkemane A, Grüter B, Novak K, Gensch T, Bönigk W, Gerharz T, Kaupp UB, Seifert R.

EMBO Rep. 2007 Aug;8(8):749-55. Epub 2007 Jul 6.

49.

Binding of Ca2+ to glutamic acid-rich polypeptides from the rod outer segment.

Haber-Pohlmeier S, Abarca-Heidemann K, Körschen HG, Dhiman HK, Heberle J, Schwalbe H, Klein-Seetharaman J, Kaupp UB, Pohlmeier A.

Biophys J. 2007 May 1;92(9):3207-14. Epub 2007 Jan 11.

50.

Fast manipulation of cellular cAMP level by light in vivo.

Schröder-Lang S, Schwärzel M, Seifert R, Strünker T, Kateriya S, Looser J, Watanabe M, Kaupp UB, Hegemann P, Nagel G.

Nat Methods. 2007 Jan;4(1):39-42. Epub 2006 Nov 26.

PMID:
17128267

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