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Items: 1 to 50 of 283


Inflammatory bowel disease in patients undergoing renal biopsies.

Pohjonen J, Nurmi R, Metso M, Oksanen P, Huhtala H, Pörsti I, Mustonen J, Kaukinen K, Mäkelä S.

Clin Kidney J. 2019 Feb 28;12(5):645-651. doi: 10.1093/ckj/sfz004. eCollection 2019 Oct.


Comparison of infectious agents detected from hatchery and wild juvenile Coho salmon in British Columbia, 2008-2018.

Nekouei O, Vanderstichel R, Kaukinen KH, Thakur K, Ming T, Patterson DA, Trudel M, Neville C, Miller KM.

PLoS One. 2019 Sep 3;14(9):e0221956. doi: 10.1371/journal.pone.0221956. eCollection 2019.


Endangered wild salmon infected by newly discovered viruses.

Mordecai GJ, Miller KM, Di Cicco E, Schulze AD, Kaukinen KH, Ming TJ, Li S, Tabata A, Teffer A, Patterson DA, Ferguson HW, Suttle CA.

Elife. 2019 Sep 3;8. pii: e47615. doi: 10.7554/eLife.47615.


Cumulative Effects of Thermal and Fisheries Stressors Reveal Sex-Specific Effects on Infection Development and Early Mortality of Adult Coho Salmon (Oncorhynchus kisutch).

Teffer AK, Hinch S, Miller K, Jeffries K, Patterson D, Cooke S, Farrell A, Kaukinen KH, Li S, Juanes F.

Physiol Biochem Zool. 2019 Sep/Oct;92(5):505-529. doi: 10.1086/705125.


Daily Life Restrictions are Common and Associated with Health Concerns and Dietary Challenges in Adult Celiac Disease Patients Diagnosed in Childhood.

Leinonen H, Kivelä L, Lähdeaho ML, Huhtala H, Kaukinen K, Kurppa K.

Nutrients. 2019 Jul 25;11(8). pii: E1718. doi: 10.3390/nu11081718.


Risk of fractures in dermatitis herpetiformis and coeliac disease: a register-based study.

Pasternack C, Koskinen I, Hervonen K, Kaukinen K, Järvelin J, Reunala T, Collin P, Huhtala H, Mattila VM, Salmi T.

Scand J Gastroenterol. 2019 Jul;54(7):843-848. doi: 10.1080/00365521.2019.1636132. Epub 2019 Jul 7.


Corrigendum to "Celiac disease or positive tissue transglutaminase antibodies in patients undergoing renal biopsies" [Dig Liver Dis (2018);50:27-31].

Nurmi R, Metso M, Pörsti I, Niemelä O, Huhtala H, Mustonen J, Kaukinen K, Mäkelä S.

Dig Liver Dis. 2019 Aug;51(8):1207-1208. doi: 10.1016/j.dld.2019.06.001. Epub 2019 Jun 26. No abstract available.


Automatic classification of IgA endomysial antibody test for celiac disease: a new method deploying machine learning.

Caetano Dos Santos FL, Michalek IM, Laurila K, Kaukinen K, Hyttinen J, Lindfors K.

Sci Rep. 2019 Jun 25;9(1):9217. doi: 10.1038/s41598-019-45679-x.


Evidence of a hydraulically challenging reach serving as a barrier for the upstream migration of infection-burdened adult steelhead.

Twardek WM, Chapman JM, Miller KM, Beere MC, Li S, Kaukinen KH, Danylchuk AJ, Cooke SJ.

Conserv Physiol. 2019 Jun 6;7(1):coz023. doi: 10.1093/conphys/coz023. eCollection 2019.


Distribution and Phylogeny of Erythrocytic Necrosis Virus (ENV) in Salmon Suggests Marine Origin.

Pagowski VA, Mordecai GJ, Miller KM, Schulze AD, Kaukinen KH, Ming TJ, Li S, Teffer AK, Tabata A, Suttle CA.

Viruses. 2019 Apr 18;11(4). pii: E358. doi: 10.3390/v11040358.


Gluten Challenge Induces Skin and Small Bowel Relapse in Long-Term Gluten-Free Diet-Treated Dermatitis Herpetiformis.

Mansikka E, Hervonen K, Kaukinen K, Ilus T, Oksanen P, Lindfors K, Laurila K, Hietikko M, Taavela J, Jernman J, Saavalainen P, Reunala T, Salmi T.

J Invest Dermatol. 2019 Oct;139(10):2108-2114. doi: 10.1016/j.jid.2019.03.1150. Epub 2019 Apr 15.


Letter: the end of duodenal biopsies in coeliac disease? Authors' reply.

Kurppa K, Fuchs V, Kaukinen K.

Aliment Pharmacol Ther. 2019 Apr;49(8):1112. doi: 10.1111/apt.15220. No abstract available.


The Phenotype of Celiac Disease Has Low Concordance between Siblings, Despite a Similar Distribution of HLA Haplotypes.

Kauma S, Kaukinen K, Huhtala H, Kivelä L, Pekki H, Salmi T, Saavalainen P, Lindfors K, Kurppa K.

Nutrients. 2019 Feb 25;11(2). pii: E479. doi: 10.3390/nu11020479.


Infectious agent detections in archived Sockeye salmon (Oncorhynchus nerka) samples from British Columbia, Canada (1985-94).

Thakur KK, Vanderstichel R, Kaukinen K, Nekouei O, Laurin E, Miller KM.

J Fish Dis. 2019 Apr;42(4):533-547. doi: 10.1111/jfd.12951. Epub 2019 Feb 11.


Coeliac disease.

Lindfors K, Ciacci C, Kurppa K, Lundin KEA, Makharia GK, Mearin ML, Murray JA, Verdu EF, Kaukinen K.

Nat Rev Dis Primers. 2019 Jan 10;5(1):3. doi: 10.1038/s41572-018-0054-z. Review.


Detection and Assessment of the Distribution of Infectious Agents in Juvenile Fraser River Sockeye Salmon, Canada, in 2012 and 2013.

Nekouei O, Vanderstichel R, Ming T, Kaukinen KH, Thakur K, Tabata A, Laurin E, Tucker S, Beacham TD, Miller KM.

Front Microbiol. 2018 Dec 21;9:3221. doi: 10.3389/fmicb.2018.03221. eCollection 2018.


Serology-based criteria for adult coeliac disease have excellent accuracy across the range of pre-test probabilities.

Fuchs V, Kurppa K, Huhtala H, Laurila K, Mäki M, Collin P, Salmi T, Luostarinen L, Saavalainen P, Kaukinen K.

Aliment Pharmacol Ther. 2019 Feb;49(3):277-284. doi: 10.1111/apt.15109. Epub 2018 Dec 27.


Small-intestinal TG2-specific plasma cells at different stages of coeliac disease.

Hietikko M, Koskinen O, Kurppa K, Laurila K, Saavalainen P, Salmi T, Ilus T, Huhtala H, Kaukinen K, Lindfors K.

BMC Immunol. 2018 Dec 6;19(1):36. doi: 10.1186/s12865-018-0275-7.


Transcriptional shifts during juvenile Coho salmon (Oncorhynchus kisutch) life stage changes in freshwater and early marine environments.

Houde ALS, Schulze AD, Kaukinen KH, Strohm J, Patterson DA, Beacham TD, Farrell AP, Hinch SG, Miller KM.

Comp Biochem Physiol Part D Genomics Proteomics. 2019 Mar;29:32-42. doi: 10.1016/j.cbd.2018.10.002. Epub 2018 Oct 18.


Microbial Biomarkers in Patients with Nonresponsive Celiac Disease.

Viitasalo L, Kurppa K, Ashorn M, Saavalainen P, Huhtala H, Ashorn S, Mäki M, Ilus T, Kaukinen K, Iltanen S.

Dig Dis Sci. 2018 Dec;63(12):3434-3441. doi: 10.1007/s10620-018-5285-z. Epub 2018 Sep 20.


Long-term health and treatment outcomes in adult coeliac disease patients diagnosed by screening in childhood.

Kivelä L, Popp A, Arvola T, Huhtala H, Kaukinen K, Kurppa K.

United European Gastroenterol J. 2018 Aug;6(7):1022-1031. doi: 10.1177/2050640618778386. Epub 2018 May 17.


Long-term follow-up in adults with coeliac disease: Predictors and effect on health outcomes.

Pekki H, Kaukinen K, Ilus T, Mäki M, Huhtala H, Laurila K, Kurppa K.

Dig Liver Dis. 2018 Nov;50(11):1189-1194. doi: 10.1016/j.dld.2018.05.015. Epub 2018 May 30.


Delayed celiac disease diagnosis predisposes to reduced quality of life and incremental use of health care services and medicines: A prospective nationwide study.

Fuchs V, Kurppa K, Huhtala H, Mäki M, Kekkonen L, Kaukinen K.

United European Gastroenterol J. 2018 May;6(4):567-575. doi: 10.1177/2050640617751253. Epub 2018 Jan 8.


Prognosis of Dermatitis Herpetiformis Patients with and without Villous Atrophy at Diagnosis.

Mansikka E, Hervonen K, Kaukinen K, Collin P, Huhtala H, Reunala T, Salmi T.

Nutrients. 2018 May 19;10(5). pii: E641. doi: 10.3390/nu10050641.


Dermatitis Herpetiformis: A Common Extraintestinal Manifestation of Coeliac Disease.

Reunala T, Salmi TT, Hervonen K, Kaukinen K, Collin P.

Nutrients. 2018 May 12;10(5). pii: E602. doi: 10.3390/nu10050602. Review.


Distinct seasonal infectious agent profiles in life-history variants of juvenile Fraser River Chinook salmon: An application of high-throughput genomic screening.

Tucker S, Li S, Kaukinen KH, Patterson DA, Miller KM.

PLoS One. 2018 Apr 19;13(4):e0195472. doi: 10.1371/journal.pone.0195472. eCollection 2018.


Olfactory gene expression in migrating adult sockeye salmon Oncorhynchus nerka.

Bett NN, Hinch SG, Kaukinen KH, Li S, Miller KM.

J Fish Biol. 2018 Jun;92(6):2029-2038. doi: 10.1111/jfb.13633. Epub 2018 May 15.


Extraintestinal manifestations were common in children with coeliac disease and were more prevalent in patients with more severe clinical and histological presentation.

Nurminen S, Kivelä L, Huhtala H, Kaukinen K, Kurppa K.

Acta Paediatr. 2019 Apr;108(4):681-687. doi: 10.1111/apa.14324. Epub 2018 Apr 19.


Self-Reported Fractures in Dermatitis Herpetiformis Compared to Coeliac Disease.

Pasternack C, Mansikka E, Kaukinen K, Hervonen K, Reunala T, Collin P, Huhtala H, Mattila VM, Salmi T.

Nutrients. 2018 Mar 14;10(3). pii: E351. doi: 10.3390/nu10030351.


Dietary Factors and Mucosal Immune Response in Celiac Disease Patients Having Persistent Symptoms Despite a Gluten-free Diet.

Laurikka P, Lindfors K, Oittinen M, Huhtala H, Salmi T, Lähdeaho ML, Ilus T, Mäki M, Kaukinen K, Kurppa K.

J Clin Gastroenterol. 2019 Aug;53(7):507-513. doi: 10.1097/MCG.0000000000001013.


Outcome measures in coeliac disease trials: the Tampere recommendations.

Ludvigsson JF, Ciacci C, Green PH, Kaukinen K, Korponay-Szabo IR, Kurppa K, Murray JA, Lundin KEA, Maki MJ, Popp A, Reilly NR, Rodriguez-Herrera A, Sanders DS, Schuppan D, Sleet S, Taavela J, Voorhees K, Walker MM, Leffler DA.

Gut. 2018 Aug;67(8):1410-1424. doi: 10.1136/gutjnl-2017-314853. Epub 2018 Feb 13.


Review article: coeliac disease in later life must not be missed.

Collin P, Vilppula A, Luostarinen L, Holmes GKT, Kaukinen K.

Aliment Pharmacol Ther. 2018 Mar;47(5):563-572. doi: 10.1111/apt.14490. Epub 2018 Jan 11. Review.


Deep sequencing of blood and gut T-cell receptor β-chains reveals gluten-induced immune signatures in celiac disease.

Yohannes DA, Freitag TL, de Kauwe A, Kaukinen K, Kurppa K, Wacklin P, Mäki M, Arstila TP, Anderson RP, Greco D, Saavalainen P.

Sci Rep. 2017 Dec 21;7(1):17977. doi: 10.1038/s41598-017-18137-9.


Elevated serum antiphospholipid antibodies in adults with celiac disease.

Laine O, Pitkänen K, Lindfors K, Huhtala H, Niemelä O, Collin P, Kurppa K, Kaukinen K.

Dig Liver Dis. 2018 May;50(5):457-461. doi: 10.1016/j.dld.2017.11.018. Epub 2017 Dec 2.


Ex vivo Culture of Duodenal Biopsies from Patients with Dermatitis Herpetiformis Indicates that Transglutaminase 3 Antibody Production Occurs in the Gut.

Hietikko M, Hervonen K, Ilus T, Salmi T, Huhtala H, Laurila K, Rauhavirta T, Reunala T, Kaukinen K, Lindfors K.

Acta Derm Venereol. 2018 Mar 13;98(3):366-372. doi: 10.2340/00015555-2849.


Parallel epigenetic modifications induced by hatchery rearing in a Pacific salmon.

Le Luyer J, Laporte M, Beacham TD, Kaukinen KH, Withler RE, Leong JS, Rondeau EB, Koop BF, Bernatchez L.

Proc Natl Acad Sci U S A. 2017 Dec 5;114(49):12964-12969. doi: 10.1073/pnas.1711229114. Epub 2017 Nov 21.


Celiac disease or positive tissue transglutaminase antibodies in patients undergoing renal biopsies.

Nurmi R, Metso M, Pörsti I, Niemelä O, Huhtala H, Mustonen J, Kaukinen K, Mäkelä S.

Dig Liver Dis. 2018 Jan;50(1):27-31. doi: 10.1016/j.dld.2017.09.131. Epub 2017 Oct 5. Erratum in: Dig Liver Dis. 2019 Aug;51(8):1207-1208.


Diagnostic Delay in Dermatitis Herpetiformis in a High-prevalence Area.

Mansikka E, Salmi T, Kaukinen K, Collin P, Huhtala H, Reunala T, Hervonen K.

Acta Derm Venereol. 2018 Feb 7;98(2):195-199. doi: 10.2340/00015555-2818.


Disappearance of epidermal transglutaminase and IgA deposits from the papillary dermis of patients with dermatitis herpetiformis after a long-term gluten-free diet.

Hietikko M, Hervonen K, Salmi T, Ilus T, Zone JJ, Kaukinen K, Reunala T, Lindfors K.

Br J Dermatol. 2018 Mar;178(3):e198-e201. doi: 10.1111/bjd.15995. Epub 2018 Jan 24. No abstract available.


Associations of tissue transglutaminase antibody seropositivity with coronary heart disease: Findings from a prospective cohort study.

Heikkilä K, Rissanen H, Heliövaara M, Knekt P, Mäki M, Kaukinen K.

Nutr Metab Cardiovasc Dis. 2017 Sep;27(9):817-821. doi: 10.1016/j.numecd.2017.06.005. Epub 2017 Jun 15.


Molecular indices of viral disease development in wild migrating salmon.

Miller KM, Günther OP, Li S, Kaukinen KH, Ming TJ.

Conserv Physiol. 2017 Jun 27;5(1):cox036. doi: 10.1093/conphys/cox036. eCollection 2017.


The Long-Term Consumption of Oats in Celiac Disease Patients Is Safe: A Large Cross-Sectional Study.

Aaltonen K, Laurikka P, Huhtala H, Mäki M, Kaukinen K, Kurppa K.

Nutrients. 2017 Jun 15;9(6). pii: E611. doi: 10.3390/nu9060611.


A B-Cell Gene Signature Correlates With the Extent of Gluten-Induced Intestinal Injury in Celiac Disease.

Garber ME, Saldanha A, Parker JS, Jones WD, Kaukinen K, Laurila K, Lähdeaho ML, Khatri P, Khosla C, Adelman DC, Mäki M.

Cell Mol Gastroenterol Hepatol. 2017 Jan 28;4(1):1-17. doi: 10.1016/j.jcmgh.2017.01.011. eCollection 2017 Jul.


Unravelling the mechanisms behind the persistent gastrointestinal symptoms in celiac disease - how can they lead to better treatment outcomes?

Laurikka P, Kaukinen K, Kurppa K.

Expert Rev Gastroenterol Hepatol. 2017 Jul;11(7):605-607. doi: 10.1080/17474124.2017.1312345. Epub 2017 Apr 3. No abstract available.


Performing routine follow-up biopsy 1 year after diagnosis does not affect long-term outcomes in coeliac disease.

Pekki H, Kurppa K, Mäki M, Huhtala H, Laurila K, Ilus T, Kaukinen K.

Aliment Pharmacol Ther. 2017 Jun;45(11):1459-1468. doi: 10.1111/apt.14048. Epub 2017 Mar 21.


Heart and skeletal muscle inflammation (HSMI) disease diagnosed on a British Columbia salmon farm through a longitudinal farm study.

Di Cicco E, Ferguson HW, Schulze AD, Kaukinen KH, Li S, Vanderstichel R, Wessel Ø, Rimstad E, Gardner IA, Hammell KL, Miller KM.

PLoS One. 2017 Feb 22;12(2):e0171471. doi: 10.1371/journal.pone.0171471. eCollection 2017.


At-Risk Screened Children with Celiac Disease are Comparable in Disease Severity and Dietary Adherence to Those Found because of Clinical Suspicion: A Large Cohort Study.

Kivelä L, Kaukinen K, Huhtala H, Lähdeaho ML, Mäki M, Kurppa K.

J Pediatr. 2017 Apr;183:115-121.e2. doi: 10.1016/j.jpeds.2016.12.077. Epub 2017 Jan 30.


Coeliac patients detected during type 1 diabetes surveillance had similar issues to those diagnosed on a clinical basis.

Laitinen AU, Agardh D, Kivelä L, Huhtala H, Lähdeaho ML, Kaukinen K, Kurppa K.

Acta Paediatr. 2017 Apr;106(4):639-646. doi: 10.1111/apa.13695. Epub 2017 Jan 13.


Transglutaminase 2-specific coeliac disease autoantibodies induce morphological changes and signs of inflammation in the small-bowel mucosa of mice.

Kalliokoski S, Piqueras VO, Frías R, Sulic AM, Määttä JA, Kähkönen N, Viiri K, Huhtala H, Pasternack A, Laurila K, Sblattero D, Korponay-Szabó IR, Mäki M, Caja S, Kaukinen K, Lindfors K.

Amino Acids. 2017 Mar;49(3):529-540. doi: 10.1007/s00726-016-2306-0. Epub 2016 Aug 9.


Dermatitis herpetiformis: a cutaneous manifestation of coeliac disease.

Collin P, Salmi TT, Hervonen K, Kaukinen K, Reunala T.

Ann Med. 2017 Feb;49(1):23-31. doi: 10.1080/07853890.2016.1222450. Epub 2016 Dec 14. Review.


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