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Items: 1 to 50 of 61


Two contrasting classes of nucleolus-associated domains in mouse fibroblast heterochromatin.

Vertii A, Ou J, Yu J, Yan A, Pagès H, Liu H, Zhu LJ, Kaufman PD.

Genome Res. 2019 Aug;29(8):1235-1249. doi: 10.1101/gr.247072.118. Epub 2019 Jun 14.


Correction to: Novel genetic tools for probing individual H3 molecules in each nucleosome.

Ichikawa Y, Kaufman PD.

Curr Genet. 2019 Apr;65(2):379-380. doi: 10.1007/s00294-018-0919-4.


Novel genetic tools for probing individual H3 molecules in each nucleosome.

Ichikawa Y, Kaufman PD.

Curr Genet. 2019 Apr;65(2):371-377. doi: 10.1007/s00294-018-0910-0. Epub 2018 Nov 26. Review. Erratum in: Curr Genet. 2018 Dec 19;:.


An asymmetric centromeric nucleosome.

Ichikawa Y, Saitoh N, Kaufman PD.

Elife. 2018 Aug 23;7. pii: e37911. doi: 10.7554/eLife.37911.


Biochemical Analysis of Dimethyl Suberimidate-crosslinked Yeast Nucleosomes.

Ichiakwa Y, Kaufman PD.

Bio Protoc. 2018 Mar 20;8(6). pii: e2770. doi: 10.21769/BioProtoc.2770.


New dimensions of asymmetric division in vertebrates.

Vertii A, Kaufman PD, Hehnly H, Doxsey S.

Cytoskeleton (Hoboken). 2018 Mar;75(3):87-102. doi: 10.1002/cm.21434. Epub 2018 Feb 8. Review.


Ki-67: more than a proliferation marker.

Sun X, Kaufman PD.

Chromosoma. 2018 Jun;127(2):175-186. doi: 10.1007/s00412-018-0659-8. Epub 2018 Jan 10. Review.


A synthetic biology approach to probing nucleosome symmetry.

Ichikawa Y, Connelly CF, Appleboim A, Miller TC, Jacobi H, Abshiru NA, Chou HJ, Chen Y, Sharma U, Zheng Y, Thomas PM, Chen HV, Bajaj V, Müller CW, Kelleher NL, Friedman N, Bolon DN, Rando OJ, Kaufman PD.

Elife. 2017 Sep 12;6. pii: e28836. doi: 10.7554/eLife.28836.


Ki-67 Contributes to Normal Cell Cycle Progression and Inactive X Heterochromatin in p21 Checkpoint-Proficient Human Cells.

Sun X, Bizhanova A, Matheson TD, Yu J, Zhu LJ, Kaufman PD.

Mol Cell Biol. 2017 Aug 11;37(17). pii: e00569-16. doi: 10.1128/MCB.00569-16. Print 2017 Sep 1.


The p150N domain of chromatin assembly factor-1 regulates Ki-67 accumulation on the mitotic perichromosomal layer.

Matheson TD, Kaufman PD.

Mol Biol Cell. 2017 Jan 1;28(1):21-29. doi: 10.1091/mbc.E16-09-0659. Epub 2016 Nov 2.


Want reprogramming? Cut back on the chromatin assembly!

Kaufman PD.

Nat Struct Mol Biol. 2015 Sep;22(9):648-50. doi: 10.1038/nsmb.3081. No abstract available.


Grabbing the genome by the NADs.

Matheson TD, Kaufman PD.

Chromosoma. 2016 Jun;125(3):361-71. doi: 10.1007/s00412-015-0527-8. Epub 2015 Jul 15. Review.


A separable domain of the p150 subunit of human chromatin assembly factor-1 promotes protein and chromosome associations with nucleoli.

Smith CL, Matheson TD, Trombly DJ, Sun X, Campeau E, Han X, Yates JR 3rd, Kaufman PD.

Mol Biol Cell. 2014 Sep 15;25(18):2866-81. doi: 10.1091/mbc.E14-05-1029. Epub 2014 Jul 23.


Chromatin-mediated Candida albicans virulence.

Lopes da Rosa J, Kaufman PD.

Biochim Biophys Acta. 2013 Mar-Apr;1819(3-4):349-55. Review.


Chemical screening identifies filastatin, a small molecule inhibitor of Candida albicans adhesion, morphogenesis, and pathogenesis.

Fazly A, Jain C, Dehner AC, Issi L, Lilly EA, Ali A, Cao H, Fidel PL Jr, Rao RP, Kaufman PD.

Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13594-9. doi: 10.1073/pnas.1305982110. Epub 2013 Jul 31.


A small molecule inhibitor of fungal histone acetyltransferase Rtt109.

Lopes da Rosa J, Bajaj V, Spoonamore J, Kaufman PD.

Bioorg Med Chem Lett. 2013 May 15;23(10):2853-9. doi: 10.1016/j.bmcl.2013.03.112. Epub 2013 Apr 4.


Chromatin-mediated Candida albicans virulence.

Lopes da Rosa J, Kaufman PD.

Biochim Biophys Acta. 2012 Mar;1819(3-4):349-55. doi: 10.1016/j.bbagrm.2011.08.007. Epub 2011 Aug 24.


Toxicity and lifespan extension: complex outcomes of histone overexpression in budding yeast.

Kaufman PD.

Cell Cycle. 2010 Dec 1;9(23):4611-2. No abstract available.


New partners for HP1 in transcriptional gene silencing.

Kaufman PD.

Mol Cell. 2011 Jan 7;41(1):1-2. doi: 10.1016/j.molcel.2010.12.021.


Catalytic activation of histone acetyltransferase Rtt109 by a histone chaperone.

Kolonko EM, Albaugh BN, Lindner SE, Chen Y, Satyshur KA, Arnold KM, Kaufman PD, Keck JL, Denu JM.

Proc Natl Acad Sci U S A. 2010 Nov 23;107(47):20275-80. doi: 10.1073/pnas.1009860107. Epub 2010 Nov 5.


Overlapping regulation of CenH3 localization and histone H3 turnover by CAF-1 and HIR proteins in Saccharomyces cerevisiae.

Lopes da Rosa J, Holik J, Green EM, Rando OJ, Kaufman PD.

Genetics. 2011 Jan;187(1):9-19. doi: 10.1534/genetics.110.123117. Epub 2010 Oct 13.


Proliferating cell nuclear antigen (PCNA) is required for cell cycle-regulated silent chromatin on replicated and nonreplicated genes.

Miller A, Chen J, Takasuka TE, Jacobi JL, Kaufman PD, Irudayaraj JM, Kirchmaier AL.

J Biol Chem. 2010 Nov 5;285(45):35142-54. doi: 10.1074/jbc.M110.166918. Epub 2010 Sep 2.


Chromatin as a potential carrier of heritable information.

Kaufman PD, Rando OJ.

Curr Opin Cell Biol. 2010 Jun;22(3):284-90. doi: 10.1016/ Epub 2010 Mar 17. Review.


Histone acetyltransferase Rtt109 is required for Candida albicans pathogenesis.

Lopes da Rosa J, Boyartchuk VL, Zhu LJ, Kaufman PD.

Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1594-9. doi: 10.1073/pnas.0912427107. Epub 2010 Jan 4.


A negatively charged residue in place of histone H3K56 supports chromatin assembly factor association but not genotoxic stress resistance.

Erkmann JA, Kaufman PD.

DNA Repair (Amst). 2009 Dec 3;8(12):1371-9. doi: 10.1016/j.dnarep.2009.09.004. Epub 2009 Sep 30.


A versatile viral system for expression and depletion of proteins in mammalian cells.

Campeau E, Ruhl VE, Rodier F, Smith CL, Rahmberg BL, Fuss JO, Campisi J, Yaswen P, Cooper PK, Kaufman PD.

PLoS One. 2009 Aug 6;4(8):e6529. doi: 10.1371/journal.pone.0006529.


Molecular functions of the histone acetyltransferase chaperone complex Rtt109-Vps75.

Berndsen CE, Tsubota T, Lindner SE, Lee S, Holton JM, Kaufman PD, Keck JL, Denu JM.

Nat Struct Mol Biol. 2008 Sep;15(9):948-56.


Cell cycle- and chaperone-mediated regulation of H3K56ac incorporation in yeast.

Kaplan T, Liu CL, Erkmann JA, Holik J, Grunstein M, Kaufman PD, Friedman N, Rando OJ.

PLoS Genet. 2008 Nov;4(11):e1000270. doi: 10.1371/journal.pgen.1000270. Epub 2008 Nov 21.


Histone H3-K56 acetylation is catalyzed by histone chaperone-dependent complexes.

Tsubota T, Berndsen CE, Erkmann JA, Smith CL, Yang L, Freitas MA, Denu JM, Kaufman PD.

Mol Cell. 2007 Mar 9;25(5):703-12. Epub 2007 Feb 22.


Histone chaperone Asf1 is required for histone H3 lysine 56 acetylation, a modification associated with S phase in mitosis and meiosis.

Recht J, Tsubota T, Tanny JC, Diaz RL, Berger JM, Zhang X, Garcia BA, Shabanowitz J, Burlingame AL, Hunt DF, Kaufman PD, Allis CD.

Proc Natl Acad Sci U S A. 2006 May 2;103(18):6988-93. Epub 2006 Apr 20.


Replication-independent histone deposition by the HIR complex and Asf1.

Green EM, Antczak AJ, Bailey AO, Franco AA, Wu KJ, Yates JR 3rd, Kaufman PD.

Curr Biol. 2005 Nov 22;15(22):2044-9.


Histone deposition proteins: links between the DNA replication machinery and epigenetic gene silencing.

Franco AA, Kaufman PD.

Cold Spring Harb Symp Quant Biol. 2004;69:201-8. Review. No abstract available.


Histone deposition protein Asf1 maintains DNA replisome integrity and interacts with replication factor C.

Franco AA, Lam WM, Burgers PM, Kaufman PD.

Genes Dev. 2005 Jun 1;19(11):1365-75. Epub 2005 May 18.


Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA.

Zhang R, Poustovoitov MV, Ye X, Santos HA, Chen W, Daganzo SM, Erzberger JP, Serebriiskii IG, Canutescu AA, Dunbrack RL, Pehrson JR, Berger JM, Kaufman PD, Adams PD.

Dev Cell. 2005 Jan;8(1):19-30.


Structure and function of the conserved core of histone deposition protein Asf1.

Daganzo SM, Erzberger JP, Lam WM, Skordalakes E, Zhang R, Franco AA, Brill SJ, Adams PD, Berger JM, Kaufman PD.

Curr Biol. 2003 Dec 16;13(24):2148-58.


The budding yeast silencing protein Sir1 is a functional component of centromeric chromatin.

Sharp JA, Krawitz DC, Gardner KA, Fox CA, Kaufman PD.

Genes Dev. 2003 Oct 1;17(19):2356-61. Epub 2003 Sep 15.


Sas4 and Sas5 are required for the histone acetyltransferase activity of Sas2 in the SAS complex.

Sutton A, Shia WJ, Band D, Kaufman PD, Osada S, Workman JL, Sternglanz R.

J Biol Chem. 2003 May 9;278(19):16887-92. Epub 2003 Mar 6.


Defective S phase chromatin assembly causes DNA damage, activation of the S phase checkpoint, and S phase arrest.

Ye X, Franco AA, Santos H, Nelson DM, Kaufman PD, Adams PD.

Mol Cell. 2003 Feb;11(2):341-51.


Chromatin proteins are determinants of centromere function.

Sharp JA, Kaufman PD.

Curr Top Microbiol Immunol. 2003;274:23-52. Review.


Defects in SPT16 or POB3 (yFACT) in Saccharomyces cerevisiae cause dependence on the Hir/Hpc pathway: polymerase passage may degrade chromatin structure.

Formosa T, Ruone S, Adams MD, Olsen AE, Eriksson P, Yu Y, Rhoades AR, Kaufman PD, Stillman DJ.

Genetics. 2002 Dec;162(4):1557-71.


Yeast histone deposition protein Asf1p requires Hir proteins and PCNA for heterochromatic silencing.

Sharp JA, Fouts ET, Krawitz DC, Kaufman PD.

Curr Biol. 2001 Apr 3;11(7):463-73.


Nucleosomal DNA regulates the core-histone-binding subunit of the human Hat1 acetyltransferase.

Verreault A, Kaufman PD, Kobayashi R, Stillman B.

Curr Biol. 1998 Jan 15;8(2):96-108.


Nucleosome assembly by a complex of CAF-1 and acetylated histones H3/H4.

Verreault A, Kaufman PD, Kobayashi R, Stillman B.

Cell. 1996 Oct 4;87(1):95-104.

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