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Items: 33


Atrial Fibrillation Progression Is Associated with Cell Senescence Burden as Determined by p53 and p16 Expression.

Jesel L, Abbas M, Park SH, Matsushita K, Kindo M, Hasan H, Auger C, Sato C, Ohlmann P, Mazzucotelli JP, Toti F, Kauffenstein G, Schini-Kerth V, Morel O.

J Clin Med. 2019 Dec 23;9(1). pii: E36. doi: 10.3390/jcm9010036.


Evidence of Cardiovascular Calcification and Fibrosis in Pseudoxanthoma Elasticum Mouse Models Subjected to DOCA-Salt Hypertension.

Omarjee L, Roy C, Leboeuf C, Favre J, Henrion D, Mahe G, Leftheriotis G, Martin L, Janin A, Kauffenstein G.

Sci Rep. 2019 Nov 8;9(1):16327. doi: 10.1038/s41598-019-52808-z.


Severe early-onset manifestations of pseudoxanthoma elasticum resulting from the cumulative effects of several deleterious mutations in ENPP1, ABCC6 and HBB: transient improvement in ectopic calcification with sodium thiosulfate.

Omarjee L, Nitschke Y, Verschuere S, Bourrat E, Vignon MD, Navasiolava N, Leftheriotis G, Kauffenstein G, Rutsch F, Vanakker OM, Martin L.

Br J Dermatol. 2019 Oct 24. doi: 10.1111/bjd.18632. [Epub ahead of print]


Thrombin Induces Angiotensin II-Mediated Senescence in Atrial Endothelial Cells: Impact on Pro-Remodeling Patterns.

Hasan H, Park SH, Auger C, Belcastro E, Matsushita K, Marchandot B, Lee HH, Qureshi AW, Kauffenstein G, Ohlmann P, Schini-Kerth VB, Jesel L, Morel O.

J Clin Med. 2019 Oct 1;8(10). pii: E1570. doi: 10.3390/jcm8101570.


Internal Carotid Artery Hypoplasia: A New Clinical Feature in Pseudoxanthoma Elasticum.

Omarjee L, Fortrat JO, Larralde A, Pabic EL, Kauffenstein G, Laot M, Navasiolava N, Mention PJ, Carrillo Linares JL, Valdivielso P, Vanakker OM, Mahé G, Martin L, Lefthériotis G.

J Stroke. 2019 Jan;21(1):108-111. doi: 10.5853/jos.2018.02705. Epub 2019 Jan 31. No abstract available.


Hydroxychloroquine partially prevents endothelial dysfunction induced by anti-beta-2-GPI antibodies in an in vivo mouse model of antiphospholipid syndrome.

Urbanski G, Caillon A, Poli C, Kauffenstein G, Begorre MA, Loufrani L, Henrion D, Belizna C.

PLoS One. 2018 Nov 6;13(11):e0206814. doi: 10.1371/journal.pone.0206814. eCollection 2018.


ABCC6 Deficiency Promotes Development of Randall Plaque.

Letavernier E, Kauffenstein G, Huguet L, Navasiolava N, Bouderlique E, Tang E, Delaitre L, Bazin D, de Frutos M, Gay C, Perez J, Verpont MC, Haymann JP, Pomozi V, Zoll J, Le Saux O, Daudon M, Leftheriotis G, Martin L.

J Am Soc Nephrol. 2018 Sep;29(9):2337-2347. doi: 10.1681/ASN.2017101148. Epub 2018 Jul 10.


Alteration of Extracellular Nucleotide Metabolism in Pseudoxanthoma Elasticum.

Kauffenstein G, Yegutkin GG, Khiati S, Pomozi V, Le Saux O, Leftheriotis G, Lenaers G, Henrion D, Martin L.

J Invest Dermatol. 2018 Aug;138(8):1862-1870. doi: 10.1016/j.jid.2018.02.023. Epub 2018 Mar 6.


Loss of vascular expression of nucleoside triphosphate diphosphohydrolase-1/CD39 in hypertension.

Roy C, Tabiasco J, Caillon A, Delneste Y, Merot J, Favre J, Guihot AL, Martin L, Nascimento DC, Ryffel B, Robson SC, Sévigny J, Henrion D, Kauffenstein G.

Purinergic Signal. 2018 Mar;14(1):73-82. doi: 10.1007/s11302-017-9597-9. Epub 2017 Dec 13.


The ABCC6 Transporter: A New Player in Biomineralization.

Favre G, Laurain A, Aranyi T, Szeri F, Fulop K, Le Saux O, Duranton C, Kauffenstein G, Martin L, Lefthériotis G.

Int J Mol Sci. 2017 Sep 11;18(9). pii: E1941. doi: 10.3390/ijms18091941. Review.


Early arterial calcification does not correlate with bone loss in pseudoxanthoma elasticum.

Martin L, Hoppé E, Kauffenstein G, Omarjee L, Navasiolava N, Henni S, Willoteaux S, Leftheriotis G.

Bone. 2017 Oct;103:88-92. doi: 10.1016/j.bone.2017.06.017. Epub 2017 Jun 27.


The ecto-ATPDase CD39 is involved in the acquisition of the immunoregulatory phenotype by M-CSF-macrophages and ovarian cancer tumor-associated macrophages: Regulatory role of IL-27.

d'Almeida SM, Kauffenstein G, Roy C, Basset L, Papargyris L, Henrion D, Catros V, Ifrah N, Descamps P, Croue A, Jeannin P, Grégoire M, Delneste Y, Tabiasco J.

Oncoimmunology. 2016 Apr 28;5(7):e1178025. doi: 10.1080/2162402X.2016.1178025. eCollection 2016 Jul.


Central Role of P2Y6 UDP Receptor in Arteriolar Myogenic Tone.

Kauffenstein G, Tamareille S, Prunier F, Roy C, Ayer A, Toutain B, Billaud M, Isakson BE, Grimaud L, Loufrani L, Rousseau P, Abraham P, Procaccio V, Monyer H, de Wit C, Boeynaems JM, Robaye B, Kwak BR, Henrion D.

Arterioscler Thromb Vasc Biol. 2016 Aug;36(8):1598-606. doi: 10.1161/ATVBAHA.116.307739. Epub 2016 Jun 2.


Nucleoside triphosphate diphosphohydrolase-1 ectonucleotidase is required for normal vas deferens contraction and male fertility through maintaining P2X1 receptor function.

Kauffenstein G, Pelletier J, Lavoie EG, Kukulski F, Martín-Satué M, Dufresne SS, Frenette J, Ribas Fürstenau C, Sereda MJ, Toutain B, Henrion D, Sullivan R, Vial C, Sévigny J.

J Biol Chem. 2014 Oct 10;289(41):28629-39. doi: 10.1074/jbc.M114.604082. Epub 2014 Aug 25.


Time-related alteration in flow- (shear stress-) mediated remodeling in resistance arteries from spontaneously hypertensive rats.

Dumont O, Kauffenstein G, Guihot AL, Guérineau NC, Abraham P, Loufrani L, Henrion D.

Int J Hypertens. 2014;2014:859793. doi: 10.1155/2014/859793. Epub 2014 May 8.


The contribution of arterial calcification to peripheral arterial disease in pseudoxanthoma elasticum.

Leftheriotis G, Kauffenstein G, Hamel JF, Abraham P, Le Saux O, Willoteaux S, Henrion D, Martin L.

PLoS One. 2014 May 6;9(5):e96003. doi: 10.1371/journal.pone.0096003. eCollection 2014.


Disseminated arterial calcification and enhanced myogenic response are associated with abcc6 deficiency in a mouse model of pseudoxanthoma elasticum.

Kauffenstein G, Pizard A, Le Corre Y, Vessières E, Grimaud L, Toutain B, Labat C, Mauras Y, Gorgels TG, Bergen AA, Le Saux O, Lacolley P, Lefthériotis G, Henrion D, Martin L.

Arterioscler Thromb Vasc Biol. 2014 May;34(5):1045-56. doi: 10.1161/ATVBAHA.113.302943. Epub 2014 Mar 27. Erratum in: Arterioscler Thromb Vasc Biol. 2015 Mar;35(3):e16.


Pseudoxanthoma elasticum: cardiac findings in patients and Abcc6-deficient mouse model.

Prunier F, Terrien G, Le Corre Y, Apana AL, Bière L, Kauffenstein G, Furber A, Bergen AA, Gorgels TG, Le Saux O, Leftheriotis G, Martin L.

PLoS One. 2013 Jul 23;8(7):e68700. doi: 10.1371/journal.pone.0068700. Print 2013.


Protective effects of angiopoietin-like 4 on cerebrovascular and functional damages in ischaemic stroke.

Bouleti C, Mathivet T, Coqueran B, Serfaty JM, Lesage M, Berland E, Ardidie-Robouant C, Kauffenstein G, Henrion D, Lapergue B, Mazighi M, Duyckaerts C, Thurston G, Valenzuela DM, Murphy AJ, Yancopoulos GD, Monnot C, Margaill I, Germain S.

Eur Heart J. 2013 Dec;34(47):3657-68. doi: 10.1093/eurheartj/eht153. Epub 2013 May 14.


Selective involvement of serum response factor in pressure-induced myogenic tone in resistance arteries.

Retailleau K, Toutain B, Galmiche G, Fassot C, Sharif-Naeini R, Kauffenstein G, Mericskay M, Duprat F, Grimaud L, Merot J, Lardeux A, Pizard A, Baudrie V, Jeunemaitre X, Feil R, Göthert JR, Lacolley P, Henrion D, Li Z, Loufrani L.

Arterioscler Thromb Vasc Biol. 2013 Feb;33(2):339-46. doi: 10.1161/ATVBAHA.112.300708. Epub 2012 Dec 20.


Emerging role of G protein-coupled receptors in microvascular myogenic tone.

Kauffenstein G, Laher I, Matrougui K, Guérineau NC, Henrion D.

Cardiovasc Res. 2012 Jul 15;95(2):223-32. doi: 10.1093/cvr/cvs152. Epub 2012 May 24. Review.


Quantification of the calcification phenotype of Abcc6-deficient mice with microcomputed tomography.

Le Corre Y, Le Saux O, Froeliger F, Libouban H, Kauffenstein G, Willoteaux S, Leftheriotis G, Martin L.

Am J Pathol. 2012 Jun;180(6):2208-13. doi: 10.1016/j.ajpath.2012.02.007. Epub 2012 Mar 31.


Coexpression of ecto-5'-nucleotidase/CD73 with specific NTPDases differentially regulates adenosine formation in the rat liver.

Fausther M, Lecka J, Soliman E, Kauffenstein G, Pelletier J, Sheung N, Dranoff JA, Sévigny J.

Am J Physiol Gastrointest Liver Physiol. 2012 Feb 15;302(4):G447-59. doi: 10.1152/ajpgi.00165.2011.. Epub 2011 Dec 1.


Identification of the ectonucleotidases expressed in mouse, rat, and human Langerhans islets: potential role of NTPDase3 in insulin secretion.

Lavoie EG, Fausther M, Kauffenstein G, Kukulski F, Künzli BM, Friess H, Sévigny J.

Am J Physiol Endocrinol Metab. 2010 Oct;299(4):E647-56. doi: 10.1152/ajpendo.00126.2010. Epub 2010 Aug 3.


Epidermal growth factor receptor is an obligatory intermediate for oxytocin-induced cyclooxygenase 2 expression and prostaglandin F2 alpha production in bovine endometrial epithelial cells.

Krishnaswamy N, Lacroix-Pepin N, Chapdelaine P, Taniguchi H, Kauffenstein G, Chakravarti A, Danyod G, Fortier MA.

Endocrinology. 2010 Mar;151(3):1367-74. doi: 10.1210/en.2009-1304. Epub 2010 Jan 15.


The ecto-nucleotidase NTPDase1 differentially regulates P2Y1 and P2Y2 receptor-dependent vasorelaxation.

Kauffenstein G, Fürstenau CR, D'Orléans-Juste P, Sévigny J.

Br J Pharmacol. 2010 Feb 1;159(3):576-85. doi: 10.1111/j.1476-5381.2009.00566.x. Epub 2010 Jan 8.


NTPDase1 (CD39) controls nucleotide-dependent vasoconstriction in mouse.

Kauffenstein G, Drouin A, Thorin-Trescases N, Bachelard H, Robaye B, D'Orléans-Juste P, Marceau F, Thorin E, Sévigny J.

Cardiovasc Res. 2010 Jan 1;85(1):204-13. doi: 10.1093/cvr/cvp265.


Extracellular ATP and P2 receptors are required for IL-8 to induce neutrophil migration.

Kukulski F, Ben Yebdri F, Lecka J, Kauffenstein G, Lévesque SA, Martín-Satué M, Sévigny J.

Cytokine. 2009 May;46(2):166-70. doi: 10.1016/j.cyto.2009.02.011. Epub 2009 Mar 19.


Inhibition of human and mouse plasma membrane bound NTPDases by P2 receptor antagonists.

Munkonda MN, Kauffenstein G, Kukulski F, Lévesque SA, Legendre C, Pelletier J, Lavoie EG, Lecka J, Sévigny J.

Biochem Pharmacol. 2007 Nov 15;74(10):1524-34. Epub 2007 Jul 27.


Identification of a unique co-operative phosphoinositide 3-kinase signaling mechanism regulating integrin alpha IIb beta 3 adhesive function in platelets.

Schoenwaelder SM, Ono A, Sturgeon S, Chan SM, Mangin P, Maxwell MJ, Turnbull S, Mulchandani M, Anderson K, Kauffenstein G, Rewcastle GW, Kendall J, Gachet C, Salem HH, Jackson SP.

J Biol Chem. 2007 Sep 28;282(39):28648-58. Epub 2007 Aug 2.


Differential regulation and relocalization of the platelet P2Y receptors after activation: a way to avoid loss of hemostatic properties?

Baurand A, Eckly A, Hechler B, Kauffenstein G, Galzi JL, Cazenave JP, Léon C, Gachet C.

Mol Pharmacol. 2005 Mar;67(3):721-33. Epub 2004 Dec 15.


Adenine triphosphate nucleotides are antagonists at the P2Y receptor.

Kauffenstein G, Hechler B, Cazenave JP, Gachet C.

J Thromb Haemost. 2004 Nov;2(11):1980-8.


The P2Y(12) receptor induces platelet aggregation through weak activation of the alpha(IIb)beta(3) integrin--a phosphoinositide 3-kinase-dependent mechanism.

Kauffenstein G, Bergmeier W, Eckly A, Ohlmann P, Léon C, Cazenave JP, Nieswandt B, Gachet C.

FEBS Lett. 2001 Sep 14;505(2):281-90.

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