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Items: 1 to 50 of 53

1.

Artesunate derivative TF27 inhibits replication and pathogenesis of an oncogenic avian alphaherpesvirus.

Bertzbach LD, Conradie AM, Hahn F, Wild M, Marschall M, Kaufer BB.

Antiviral Res. 2019 Sep 11:104606. doi: 10.1016/j.antiviral.2019.104606. [Epub ahead of print]

PMID:
31520682
2.

Chromatin Profiles of Chromosomally Integrated Human Herpesvirus-6A.

Saviola AJ, Zimmermann C, Mariani MP, Signorelli SA, Gerrard DL, Boyd JR, Wight DJ, Morissette G, Gravel A, Dubuc I, Flamand L, Kaufer BB, Frietze S.

Front Microbiol. 2019 Jun 26;10:1408. doi: 10.3389/fmicb.2019.01408. eCollection 2019.

3.

Transmission of chromosomally integrated human herpes virus-6A via haploidentical stem cell transplantation poses a risk for virus reactivation and associated complications.

Oevermann L, Zimmermann C, Voigt S, Künkele A, Lobitz S, Eggert A, Schulte JH, Kaufer BB, Deubzer HE.

Bone Marrow Transplant. 2019 Apr 15. doi: 10.1038/s41409-019-0530-4. [Epub ahead of print] No abstract available.

PMID:
30988380
4.

Replication of Marek's Disease Virus Is Dependent on Synthesis of De Novo Fatty Acid and Prostaglandin E2.

Boodhoo N, Kamble N, Kaufer BB, Behboudi S.

J Virol. 2019 Jun 14;93(13). pii: e00352-19. doi: 10.1128/JVI.00352-19. Print 2019 Jul 1.

5.

The Transcriptional Landscape of Marek's Disease Virus in Primary Chicken B Cells Reveals Novel Splice Variants and Genes.

Bertzbach LD, Pfaff F, Pauker VI, Kheimar AM, Höper D, Härtle S, Karger A, Kaufer BB.

Viruses. 2019 Mar 16;11(3). pii: E264. doi: 10.3390/v11030264.

6.

Overexpression of cellular telomerase RNA enhances virus-induced cancer formation.

Kheimar A, Trimpert J, Groenke N, Kaufer BB.

Oncogene. 2019 Mar;38(10):1778-1786. doi: 10.1038/s41388-018-0544-1. Epub 2018 Oct 19.

PMID:
30846849
7.

The Role of Marek's Disease Virus UL12 and UL29 in DNA Recombination and the Virus Lifecycle.

Previdelli RL, Bertzbach LD, Wight DJ, Vychodil T, You Y, Arndt S, Kaufer BB.

Viruses. 2019 Jan 28;11(2). pii: E111. doi: 10.3390/v11020111.

8.

LANA oligomeric architecture is essential for KSHV nuclear body formation and viral genome maintenance during latency.

De Leo A, Deng Z, Vladimirova O, Chen HS, Dheekollu J, Calderon A, Myers KA, Hayden J, Keeney F, Kaufer BB, Yuan Y, Robertson E, Lieberman PM.

PLoS Pathog. 2019 Jan 25;15(1):e1007489. doi: 10.1371/journal.ppat.1007489. eCollection 2019 Jan.

9.

Imaging Mass Spectrometry and Proteome Analysis of Marek's Disease Virus-Induced Tumors.

Pauker VI, Bertzbach LD, Hohmann A, Kheimar A, Teifke JP, Mettenleiter TC, Karger A, Kaufer BB.

mSphere. 2019 Jan 16;4(1). pii: e00569-18. doi: 10.1128/mSphere.00569-18.

10.

Viral Proteins U41 and U70 of Human Herpesvirus 6A Are Dispensable for Telomere Integration.

Wight DJ, Wallaschek N, Sanyal A, Weller SK, Flamand L, Kaufer BB.

Viruses. 2018 Nov 21;10(11). pii: E656. doi: 10.3390/v10110656.

11.

In vivo proof-of-concept for two experimental antiviral drugs, both directed to cellular targets, using a murine cytomegalovirus model.

Sonntag E, Hahn F, Bertzbach LD, Seyler L, Wangen C, Müller R, Tannig P, Grau B, Baumann M, Zent E, Zischinsky G, Eickhoff J, Kaufer BB, Bäuerle T, Tsogoeva SB, Marschall M.

Antiviral Res. 2019 Jan;161:63-69. doi: 10.1016/j.antiviral.2018.11.008. Epub 2018 Nov 17.

PMID:
30452929
12.

Unraveling the role of B cells in the pathogenesis of an oncogenic avian herpesvirus.

Bertzbach LD, Laparidou M, Härtle S, Etches RJ, Kaspers B, Schusser B, Kaufer BB.

Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):11603-11607. doi: 10.1073/pnas.1813964115. Epub 2018 Oct 18.

13.

The ND10 Complex Represses Lytic Human Herpesvirus 6A Replication and Promotes Silencing of the Viral Genome.

Sanyal A, Wallaschek N, Glass M, Flamand L, Wight DJ, Kaufer BB.

Viruses. 2018 Jul 29;10(8). pii: E401. doi: 10.3390/v10080401.

14.

Artesunate-derived monomeric, dimeric and trimeric experimental drugs - Their unique mechanistic basis and pronounced antiherpesviral activity.

Hahn F, Fröhlich T, Frank T, Bertzbach LD, Kohrt S, Kaufer BB, Stamminger T, Tsogoeva SB, Marschall M.

Antiviral Res. 2018 Apr;152:104-110. doi: 10.1016/j.antiviral.2018.02.013. Epub 2018 Feb 16.

PMID:
29458133
15.

Attenuation of Simian Varicella Virus Infection by Enhanced Green Fluorescent Protein in Rhesus Macaques.

Mahalingam R, Kaufer BB, Ouwendijk WJD, Verjans GMGM, Coleman C, Hunter M, Das A, Palmer BE, Clambey E, Nagel MA, Traina-Dorge V.

J Virol. 2018 Mar 14;92(7). pii: e02253-17. doi: 10.1128/JVI.02253-17. Print 2018 Apr 1.

16.

Identification of the Receptor and Cellular Ortholog of the Marek's Disease Virus (MDV) CXC Chemokine.

Haertle S, Alzuheir I, Busalt F, Waters V, Kaiser P, Kaufer BB.

Front Microbiol. 2017 Dec 15;8:2543. doi: 10.3389/fmicb.2017.02543. eCollection 2017.

17.
18.

Association of Marek's Disease induced immunosuppression with activation of a novel regulatory T cells in chickens.

Gurung A, Kamble N, Kaufer BB, Pathan A, Behboudi S.

PLoS Pathog. 2017 Dec 21;13(12):e1006745. doi: 10.1371/journal.ppat.1006745. eCollection 2017 Dec.

19.

Summary of the 10th International Conference on Human Herpesviruses-6 and -7 (HHV-6A, -6B, and HHV-7).

Komaroff AL, Boeckh M, Eliason E, Phan T, Kaufer BB.

J Med Virol. 2018 Apr;90(4):625-630. doi: 10.1002/jmv.25004. Epub 2018 Jan 4.

PMID:
29266397
20.

Induction of DNA Damages upon Marek's Disease Virus Infection: Implication in Viral Replication and Pathogenesis.

Bencherit D, Remy S, Le Vern Y, Vychodil T, Bertzbach LD, Kaufer BB, Denesvre C, Trapp-Fragnet L.

J Virol. 2017 Nov 30;91(24). pii: e01658-17. doi: 10.1128/JVI.01658-17. Print 2017 Dec 15.

21.

Telomeres and Telomerase: Role in Marek's Disease Virus Pathogenesis, Integration and Tumorigenesis.

Kheimar A, Previdelli RL, Wight DJ, Kaufer BB.

Viruses. 2017 Jul 4;9(7). pii: E173. doi: 10.3390/v9070173. Review.

22.

Varicella zoster virus glycoprotein C increases chemokine-mediated leukocyte migration.

González-Motos V, Jürgens C, Ritter B, Kropp KA, Durán V, Larsen O, Binz A, Ouwendijk WJD, Lenac Rovis T, Jonjic S, Verjans GMGM, Sodeik B, Krey T, Bauerfeind R, Schulz TF, Kaufer BB, Kalinke U, Proudfoot AEI, Rosenkilde MM, Viejo-Borbolla A.

PLoS Pathog. 2017 May 25;13(5):e1006346. doi: 10.1371/journal.ppat.1006346. eCollection 2017 May.

23.

Stabilization of Telomere G-Quadruplexes Interferes with Human Herpesvirus 6A Chromosomal Integration.

Gilbert-Girard S, Gravel A, Artusi S, Richter SN, Wallaschek N, Kaufer BB, Flamand L.

J Virol. 2017 Jun 26;91(14). pii: e00402-17. doi: 10.1128/JVI.00402-17. Print 2017 Jul 15.

24.

Cell Culture Systems To Study Human Herpesvirus 6A/B Chromosomal Integration.

Gravel A, Dubuc I, Wallaschek N, Gilbert-Girard S, Collin V, Hall-Sedlak R, Jerome KR, Mori Y, Carbonneau J, Boivin G, Kaufer BB, Flamand L.

J Virol. 2017 Jun 26;91(14). pii: e00437-17. doi: 10.1128/JVI.00437-17. Print 2017 Jul 15.

25.

The Prolyl Isomerase Pin1 Promotes the Herpesvirus-Induced Phosphorylation-Dependent Disassembly of the Nuclear Lamina Required for Nucleocytoplasmic Egress.

Milbradt J, Hutterer C, Bahsi H, Wagner S, Sonntag E, Horn AH, Kaufer BB, Mori Y, Sticht H, Fossen T, Marschall M.

PLoS Pathog. 2016 Aug 24;12(8):e1005825. doi: 10.1371/journal.ppat.1005825. eCollection 2016 Aug.

26.

Varicella zoster virus infection of human fetal lung cells alters mitochondrial morphology.

Keller AC, Badani H, McClatchey PM, Baird NL, Bowlin JL, Bouchard R, Perng GC, Reusch JE, Kaufer BB, Gilden D, Shahzad A, Kennedy PG, Cohrs RJ.

J Neurovirol. 2016 Oct;22(5):674-682. Epub 2016 May 31.

27.

The Telomeric Repeats of Human Herpesvirus 6A (HHV-6A) Are Required for Efficient Virus Integration.

Wallaschek N, Sanyal A, Pirzer F, Gravel A, Mori Y, Flamand L, Kaufer BB.

PLoS Pathog. 2016 May 31;12(5):e1005666. doi: 10.1371/journal.ppat.1005666. eCollection 2016 May.

28.

The putative U94 integrase is dispensable for human herpesvirus 6 (HHV-6) chromosomal integration.

Wallaschek N, Gravel A, Flamand L, Kaufer BB.

J Gen Virol. 2016 Aug;97(8):1899-903. doi: 10.1099/jgv.0.000502. Epub 2016 May 11.

PMID:
27170009
29.

Generation of an Avian-Mammalian Rotavirus Reassortant by Using a Helper Virus-Dependent Reverse Genetics System.

Johne R, Reetz J, Kaufer BB, Trojnar E.

J Virol. 2015 Nov 18;90(3):1439-43. doi: 10.1128/JVI.02730-15. Print 2016 Feb 1.

30.

In vitro model for lytic replication, latency, and transformation of an oncogenic alphaherpesvirus.

Schermuly J, Greco A, Härtle S, Osterrieder N, Kaufer BB, Kaspers B.

Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):7279-84. doi: 10.1073/pnas.1424420112. Epub 2015 May 26.

31.

Characterization of human herpesvirus 6A/B U94 as ATPase, helicase, exonuclease and DNA-binding proteins.

Trempe F, Gravel A, Dubuc I, Wallaschek N, Collin V, Gilbert-Girard S, Morissette G, Kaufer BB, Flamand L.

Nucleic Acids Res. 2015 Jul 13;43(12):6084-98. doi: 10.1093/nar/gkv503. Epub 2015 May 20.

32.

3D tissue-like assemblies: A novel approach to investigate virus-cell interactions.

Goodwin TJ, McCarthy M, Cohrs RJ, Kaufer BB.

Methods. 2015 Nov 15;90:76-84. doi: 10.1016/j.ymeth.2015.05.010. Epub 2015 May 15.

33.

Chromosomally integrated HHV-6: impact on virus, cell and organismal biology.

Kaufer BB, Flamand L.

Curr Opin Virol. 2014 Dec;9:111-8. doi: 10.1016/j.coviro.2014.09.010. Epub 2014 Oct 29. Review.

PMID:
25462442
34.

Chromosomally integrated human herpesvirus 6 in heart failure: prevalence and treatment.

Kühl U, Lassner D, Wallaschek N, Gross UM, Krueger GR, Seeberg B, Kaufer BB, Escher F, Poller W, Schultheiss HP.

Eur J Heart Fail. 2015 Jan;17(1):9-19. doi: 10.1002/ejhf.194. Epub 2014 Nov 11.

35.

Herpesvirus Genome Integration into Telomeric Repeats of Host Cell Chromosomes.

Osterrieder N, Wallaschek N, Kaufer BB.

Annu Rev Virol. 2014 Nov;1(1):215-35. doi: 10.1146/annurev-virology-031413-085422. Epub 2014 Jun 27.

PMID:
26958721
36.

Role of the short telomeric repeat region in Marek's disease virus replication, genomic integration, and lymphomagenesis.

Greco A, Fester N, Engel AT, Kaufer BB.

J Virol. 2014 Dec;88(24):14138-47. doi: 10.1128/JVI.02437-14. Epub 2014 Oct 1.

37.

Detection of integrated herpesvirus genomes by fluorescence in situ hybridization (FISH).

Kaufer BB.

Methods Mol Biol. 2013;1064:141-52. doi: 10.1007/978-1-62703-601-6_10.

PMID:
23996255
38.

Three-dimensional normal human neural progenitor tissue-like assemblies: a model of persistent varicella-zoster virus infection.

Goodwin TJ, McCarthy M, Osterrieder N, Cohrs RJ, Kaufer BB.

PLoS Pathog. 2013;9(8):e1003512. doi: 10.1371/journal.ppat.1003512. Epub 2013 Aug 1.

39.

Marek's disease virus (MDV) ubiquitin-specific protease (USP) performs critical functions beyond its enzymatic activity during virus replication.

Veiga IB, Jarosinski KW, Kaufer BB, Osterrieder N.

Virology. 2013 Mar 15;437(2):110-7. doi: 10.1016/j.virol.2013.01.003. Epub 2013 Feb 9.

40.

Marek's disease viral interleukin-8 promotes lymphoma formation through targeted recruitment of B cells and CD4+ CD25+ T cells.

Engel AT, Selvaraj RK, Kamil JP, Osterrieder N, Kaufer BB.

J Virol. 2012 Aug;86(16):8536-45. doi: 10.1128/JVI.00556-12. Epub 2012 May 30.

41.

Viral bacterial artificial chromosomes: generation, mutagenesis, and removal of mini-F sequences.

Tischer BK, Kaufer BB.

J Biomed Biotechnol. 2012;2012:472537. doi: 10.1155/2012/472537. Epub 2012 Feb 23. Review.

42.

Elimination half-life of intravenously administered equine cardiac troponin I in healthy ponies.

Kraus MS, Kaufer BB, Damiani A, Osterrieder N, Rishniw M, Schwark W, Gelzer AR, Divers TJ.

Equine Vet J. 2013 Jan;45(1):56-9. doi: 10.1111/j.2042-3306.2012.00554.x. Epub 2012 Mar 20.

PMID:
22432543
43.

Fluorescently tagged pUL47 of Marek's disease virus reveals differential tissue expression of the tegument protein in vivo.

Jarosinski KW, Arndt S, Kaufer BB, Osterrieder N.

J Virol. 2012 Mar;86(5):2428-36. doi: 10.1128/JVI.06719-11. Epub 2011 Dec 21.

44.

Herpesvirus telomerase RNA (vTR) with a mutated template sequence abrogates herpesvirus-induced lymphomagenesis.

Kaufer BB, Arndt S, Trapp S, Osterrieder N, Jarosinski KW.

PLoS Pathog. 2011 Oct;7(10):e1002333. doi: 10.1371/journal.ppat.1002333. Epub 2011 Oct 27.

45.

Simian varicella virus open reading frame 63/70 expression is required for efficient virus replication in culture.

Brazeau E, Wellish M, Kaufer BB, Tischer BK, Gray W, Zhou F, Osterrieder N, Hanlon T, Golive A, Hall T, Nair S, Owens GP, Mueller NH, Cohrs RJ, Pugazhenthi S, Gilden D, Mahalingam R.

J Neurovirol. 2011 Jun;17(3):274-80. doi: 10.1007/s13365-011-0025-6. Epub 2011 Apr 9.

46.

Herpesvirus telomeric repeats facilitate genomic integration into host telomeres and mobilization of viral DNA during reactivation.

Kaufer BB, Jarosinski KW, Osterrieder N.

J Exp Med. 2011 Mar 14;208(3):605-15. doi: 10.1084/jem.20101402. Epub 2011 Mar 7.

47.

Herpesvirus telomerase RNA(vTR)-dependent lymphoma formation does not require interaction of vTR with telomerase reverse transcriptase (TERT).

Kaufer BB, Trapp S, Jarosinski KW, Osterrieder N.

PLoS Pathog. 2010 Aug 26;6(8):e1001073. doi: 10.1371/journal.ppat.1001073.

48.

The varicella-zoster virus ORFS/L (ORF0) gene is required for efficient viral replication and contains an element involved in DNA cleavage.

Kaufer BB, Smejkal B, Osterrieder N.

J Virol. 2010 Nov;84(22):11661-9. doi: 10.1128/JVI.00878-10. Epub 2010 Sep 15.

49.

Varicella-zoster virus-induced apoptosis in MeWo cells is accompanied by down-regulation of Bcl-2 expression.

Brazeau E, Mahalingam R, Gilden D, Wellish M, Kaufer BB, Osterrieder N, Pugazhenthi S.

J Neurovirol. 2010 Mar;16(2):133-40. doi: 10.3109/13550281003682547.

50.

Analysis of the herpesvirus chemokine-binding glycoprotein G residues essential for chemokine binding and biological activity.

Van de Walle GR, Kaufer BB, Chbab N, Osterrieder N.

J Biol Chem. 2009 Feb 27;284(9):5968-76. doi: 10.1074/jbc.M808127200. Epub 2008 Dec 12.

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