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Items: 1 to 50 of 303

1.

Multigenic DNA vaccine induces protective cross-reactive T cell responses against heterologous influenza virus in nonhuman primates.

Koday MT, Leonard JA, Munson P, Forero A, Koday M, Bratt DL, Fuller JT, Murnane R, Qin S, Reinhart TA, Duus K, Messaoudi I, Hartman AL, Stefano-Cole K, Morrison J, Katze MG, Fuller DH.

PLoS One. 2017 Dec 21;12(12):e0189780. doi: 10.1371/journal.pone.0189780. eCollection 2017.

2.

Evaluation of the innate immune responses to influenza and live-attenuated influenza vaccine infection in primary differentiated human nasal epithelial cells.

Forero A, Fenstermacher K, Wohlgemuth N, Nishida A, Carter V, Smith EA, Peng X, Hayes M, Francis D, Treanor J, Morrison J, Klein SL, Lane A, Katze MG, Pekosz A.

Vaccine. 2017 Oct 27;35(45):6112-6121. doi: 10.1016/j.vaccine.2017.09.058. Epub 2017 Sep 28.

3.

Ebola Virus Binding to Tim-1 on T Lymphocytes Induces a Cytokine Storm.

Younan P, Iampietro M, Nishida A, Ramanathan P, Santos RI, Dutta M, Lubaki NM, Koup RA, Katze MG, Bukreyev A.

MBio. 2017 Sep 26;8(5). pii: e00845-17. doi: 10.1128/mBio.00845-17.

4.

Early nasopharyngeal microbial signature associated with severe influenza in children: a retrospective pilot study.

Langevin S, Pichon M, Smith E, Morrison J, Bent Z, Green R, Barker K, Solberg O, Gillet Y, Javouhey E, Lina B, Katze MG, Josset L.

J Gen Virol. 2017 Oct;98(10):2425-2437. doi: 10.1099/jgv.0.000920. Epub 2017 Sep 8.

PMID:
28884664
5.

Ebola virus glycoprotein directly triggers T lymphocyte death despite of the lack of infection.

Iampietro M, Younan P, Nishida A, Dutta M, Lubaki NM, Santos RI, Koup RA, Katze MG, Bukreyev A.

PLoS Pathog. 2017 May 22;13(5):e1006397. doi: 10.1371/journal.ppat.1006397. eCollection 2017 May.

6.

Ebolaviruses Associated with Differential Pathogenicity Induce Distinct Host Responses in Human Macrophages.

Olejnik J, Forero A, Deflubé LR, Hume AJ, Manhart WA, Nishida A, Marzi A, Katze MG, Ebihara H, Rasmussen AL, Mühlberger E.

J Virol. 2017 May 12;91(11). pii: e00179-17. doi: 10.1128/JVI.00179-17. Print 2017 Jun 1.

7.

A Systems Approach Reveals MAVS Signaling in Myeloid Cells as Critical for Resistance to Ebola Virus in Murine Models of Infection.

Dutta M, Robertson SJ, Okumura A, Scott DP, Chang J, Weiss JM, Sturdevant GL, Feldmann F, Haddock E, Chiramel AI, Ponia SS, Dougherty JD, Katze MG, Rasmussen AL, Best SM.

Cell Rep. 2017 Jan 17;18(3):816-829. doi: 10.1016/j.celrep.2016.12.069.

8.

The effect of inhibition of PP1 and TNFα signaling on pathogenesis of SARS coronavirus.

McDermott JE, Mitchell HD, Gralinski LE, Eisfeld AJ, Josset L, Bankhead A 3rd, Neumann G, Tilton SC, Schäfer A, Li C, Fan S, McWeeney S, Baric RS, Katze MG, Waters KM.

BMC Syst Biol. 2016 Sep 23;10(1):93.

9.

Anomaly Detection in Host Signaling Pathways for the Early Prognosis of Acute Infection.

Wang K, Langevin S, O'Hern CS, Shattuck MD, Ogle S, Forero A, Morrison J, Slayden R, Katze MG, Kirby M.

PLoS One. 2016 Aug 17;11(8):e0160919. doi: 10.1371/journal.pone.0160919. eCollection 2016.

10.

Genomic Signatures of Emerging Viruses: A New Era of Systems Epidemiology.

Rasmussen AL, Katze MG.

Cell Host Microbe. 2016 May 11;19(5):611-8. doi: 10.1016/j.chom.2016.04.016. Review.

11.

FCGR2C Polymorphisms Associated with HIV-1 Vaccine Protection Are Linked to Altered Gene Expression of Fc-γ Receptors in Human B Cells.

Peng X, Li SS, Gilbert PB, Geraghty DE, Katze MG.

PLoS One. 2016 Mar 25;11(3):e0152425. doi: 10.1371/journal.pone.0152425. eCollection 2016.

12.

Integrated Omics Analysis of Pathogenic Host Responses during Pandemic H1N1 Influenza Virus Infection: The Crucial Role of Lipid Metabolism.

Tisoncik-Go J, Gasper DJ, Kyle JE, Eisfeld AJ, Selinger C, Hatta M, Morrison J, Korth MJ, Zink EM, Kim YM, Schepmoes AA, Nicora CD, Purvine SO, Weitz KK, Peng X, Green RR, Tilton SC, Webb-Robertson BJ, Waters KM, Metz TO, Smith RD, Kawaoka Y, Suresh M, Josset L, Katze MG.

Cell Host Microbe. 2016 Feb 10;19(2):254-66. doi: 10.1016/j.chom.2016.01.002.

13.

The 1918 Influenza Virus PB2 Protein Enhances Virulence through the Disruption of Inflammatory and Wnt-Mediated Signaling in Mice.

Forero A, Tisoncik-Go J, Watanabe T, Zhong G, Hatta M, Tchitchek N, Selinger C, Chang J, Barker K, Morrison J, Berndt JD, Moon RT, Josset L, Kawaoka Y, Katze MG.

J Virol. 2015 Dec 9;90(5):2240-53. doi: 10.1128/JVI.02974-15.

14.

Genome Wide Identification of SARS-CoV Susceptibility Loci Using the Collaborative Cross.

Gralinski LE, Ferris MT, Aylor DL, Whitmore AC, Green R, Frieman MB, Deming D, Menachery VD, Miller DR, Buus RJ, Bell TA, Churchill GA, Threadgill DW, Katze MG, McMillan L, Valdar W, Heise MT, Pardo-Manuel de Villena F, Baric RS.

PLoS Genet. 2015 Oct 9;11(10):e1005504. doi: 10.1371/journal.pgen.1005504. eCollection 2015 Oct.

15.

Suppressor of Cytokine Signaling 3 Is an Inducible Host Factor That Regulates Virus Egress during Ebola Virus Infection.

Okumura A, Rasmussen AL, Halfmann P, Feldmann F, Yoshimura A, Feldmann H, Kawaoka Y, Harty RN, Katze MG.

J Virol. 2015 Oct;89(20):10399-406. doi: 10.1128/JVI.01736-15. Epub 2015 Aug 5.

16.

Flavivirus Antagonism of Type I Interferon Signaling Reveals Prolidase as a Regulator of IFNAR1 Surface Expression.

Lubick KJ, Robertson SJ, McNally KL, Freedman BA, Rasmussen AL, Taylor RT, Walts AD, Tsuruda S, Sakai M, Ishizuka M, Boer EF, Foster EC, Chiramel AI, Addison CB, Green R, Kastner DL, Katze MG, Holland SM, Forlino A, Freeman AF, Boehm M, Yoshii K, Best SM.

Cell Host Microbe. 2015 Jul 8;18(1):61-74. doi: 10.1016/j.chom.2015.06.007.

17.

Toll-Like Receptor 3 Signaling via TRIF Contributes to a Protective Innate Immune Response to Severe Acute Respiratory Syndrome Coronavirus Infection.

Totura AL, Whitmore A, Agnihothram S, Schäfer A, Katze MG, Heise MT, Baric RS.

MBio. 2015 May 26;6(3):e00638-15. doi: 10.1128/mBio.00638-15.

18.

SIV Infection of Lung Macrophages.

Li Y, Kang G, Duan L, Lu W, Katze MG, Lewis MG, Haase AT, Li Q.

PLoS One. 2015 May 1;10(5):e0125500. doi: 10.1371/journal.pone.0125500. eCollection 2015.

19.

Antioxidants Complement the Requirement for Protein Chaperone Function to Maintain β-Cell Function and Glucose Homeostasis.

Han J, Song B, Kim J, Kodali VK, Pottekat A, Wang M, Hassler J, Wang S, Pennathur S, Back SH, Katze MG, Kaufman RJ.

Diabetes. 2015 Aug;64(8):2892-904. doi: 10.2337/db14-1357. Epub 2015 Mar 20.

20.

Gene expression signatures as a therapeutic target for severe H7N9 influenza - what do we know so far?

Morrison J, Katze MG.

Expert Opin Ther Targets. 2015 Apr;19(4):447-50. doi: 10.1517/14728222.2015.1006198. Epub 2015 Jan 20.

PMID:
25600759
21.

Next-generation sequencing reveals a controlled immune response to Zaire Ebola virus challenge in cynomolgus macaques immunized with vesicular stomatitis virus expressing Zaire Ebola virus glycoprotein (VSVΔG/EBOVgp).

Barrenas F, Green RR, Thomas MJ, Law GL, Proll SC, Engelmann F, Messaoudi I, Marzi A, Feldmann H, Katze MG.

Clin Vaccine Immunol. 2015 Mar;22(3):354-6. doi: 10.1128/CVI.00733-14. Epub 2015 Jan 14.

22.

Cytokine systems approach demonstrates differences in innate and pro-inflammatory host responses between genetically distinct MERS-CoV isolates.

Selinger C, Tisoncik-Go J, Menachery VD, Agnihothram S, Law GL, Chang J, Kelly SM, Sova P, Baric RS, Katze MG.

BMC Genomics. 2014 Dec 22;15:1161. doi: 10.1186/1471-2164-15-1161.

23.

Delayed inflammatory and cell death responses are associated with reduced pathogenicity in Lujo virus-infected cynomolgus macaques.

Rasmussen AL, Tchitchek N, Safronetz D, Carter VS, Williams CM, Haddock E, Korth MJ, Feldmann H, Katze MG.

J Virol. 2015 Mar;89(5):2543-52. doi: 10.1128/JVI.02246-14. Epub 2014 Dec 17.

24.

The draft genome sequence of the ferret (Mustela putorius furo) facilitates study of human respiratory disease.

Peng X, Alföldi J, Gori K, Eisfeld AJ, Tyler SR, Tisoncik-Go J, Brawand D, Law GL, Skunca N, Hatta M, Gasper DJ, Kelly SM, Chang J, Thomas MJ, Johnson J, Berlin AM, Lara M, Russell P, Swofford R, Turner-Maier J, Young S, Hourlier T, Aken B, Searle S, Sun X, Yi Y, Suresh M, Tumpey TM, Siepel A, Wisely SM, Dessimoz C, Kawaoka Y, Birren BW, Lindblad-Toh K, Di Palma F, Engelhardt JF, Palermo RE, Katze MG.

Nat Biotechnol. 2014 Dec;32(12):1250-5. doi: 10.1038/nbt.3079. Epub 2014 Nov 17.

25.

Sequencing, annotation and analysis of the Syrian hamster (Mesocricetus auratus) transcriptome.

Tchitchek N, Safronetz D, Rasmussen AL, Martens C, Virtaneva K, Porcella SF, Feldmann H, Ebihara H, Katze MG.

PLoS One. 2014 Nov 14;9(11):e112617. doi: 10.1371/journal.pone.0112617. eCollection 2014. Erratum in: PLoS One. 2015;10(2):e0117958.

26.

Tissue-specific transcriptome sequencing analysis expands the non-human primate reference transcriptome resource (NHPRTR).

Peng X, Thierry-Mieg J, Thierry-Mieg D, Nishida A, Pipes L, Bozinoski M, Thomas MJ, Kelly S, Weiss JM, Raveendran M, Muzny D, Gibbs RA, Rogers J, Schroth GP, Katze MG, Mason CE.

Nucleic Acids Res. 2015 Jan;43(Database issue):D737-42. doi: 10.1093/nar/gku1110. Epub 2014 Nov 11.

27.

Host genetic diversity enables Ebola hemorrhagic fever pathogenesis and resistance.

Rasmussen AL, Okumura A, Ferris MT, Green R, Feldmann F, Kelly SM, Scott DP, Safronetz D, Haddock E, LaCasse R, Thomas MJ, Sova P, Carter VS, Weiss JM, Miller DR, Shaw GD, Korth MJ, Heise MT, Baric RS, de Villena FP, Feldmann H, Katze MG.

Science. 2014 Nov 21;346(6212):987-91. doi: 10.1126/science.1259595. Epub 2014 Oct 30.

28.

Enabling large-scale next-generation sequence assembly with Blacklight.

Couger MB, Pipes L, Squina F, Prade R, Siepel A, Palermo R, Katze MG, Mason CE, Blood PD.

Concurr Comput. 2014 Sep 10;26(13):2157-2166.

29.

Multiple low-dose challenges in a rhesus macaque AIDS vaccine trial result in an evolving host response that affects protective outcome.

Selinger C, Strbo N, Gonzalez L, Aicher L, Weiss JM, Law GL, Palermo RE, Vaccari M, Franchini G, Podack ER, Katze MG.

Clin Vaccine Immunol. 2014 Dec;21(12):1650-60. doi: 10.1128/CVI.00455-14. Epub 2014 Oct 1.

30.

Infection with MERS-CoV causes lethal pneumonia in the common marmoset.

Falzarano D, de Wit E, Feldmann F, Rasmussen AL, Okumura A, Peng X, Thomas MJ, van Doremalen N, Haddock E, Nagy L, LaCasse R, Liu T, Zhu J, McLellan JS, Scott DP, Katze MG, Feldmann H, Munster VJ.

PLoS Pathog. 2014 Aug 21;10(8):e1004250. doi: 10.1371/journal.ppat.1004250. eCollection 2014 Aug. Erratum in: PLoS Pathog. 2014 Sep;10(9):e1004431.

31.

Influenza virus A/Anhui/1/2013 (H7N9) replicates efficiently in the upper and lower respiratory tracts of cynomolgus macaques.

de Wit E, Rasmussen AL, Feldmann F, Bushmaker T, Martellaro C, Haddock E, Okumura A, Proll SC, Chang J, Gardner D, Katze MG, Munster VJ, Feldmann H.

MBio. 2014 Aug 12;5(4). pii: e01331-14. doi: 10.1128/mBio.01331-14.

32.

A proteomic glimpse into the initial global epigenetic changes during HIV infection.

Britton LM, Sova P, Belisle S, Liu S, Chan EY, Katze MG, Garcia BA.

Proteomics. 2014 Oct;14(19):2226-30. doi: 10.1002/pmic.201400116. Epub 2014 Sep 5.

33.

H7N9 and other pathogenic avian influenza viruses elicit a three-pronged transcriptomic signature that is reminiscent of 1918 influenza virus and is associated with lethal outcome in mice.

Morrison J, Josset L, Tchitchek N, Chang J, Belser JA, Swayne DE, Pantin-Jackwood MJ, Tumpey TM, Katze MG.

J Virol. 2014 Sep;88(18):10556-68. doi: 10.1128/JVI.00570-14. Epub 2014 Jul 2.

34.

Annotation of long non-coding RNAs expressed in collaborative cross founder mice in response to respiratory virus infection reveals a new class of interferon-stimulated transcripts.

Josset L, Tchitchek N, Gralinski LE, Ferris MT, Eisfeld AJ, Green RR, Thomas MJ, Tisoncik-Go J, Schroth GP, Kawaoka Y, Manuel de Villena FP, Baric RS, Heise MT, Peng X, Katze MG.

RNA Biol. 2014;11(7):875-90. doi: 10.4161/rna.29442. Epub 2014 Jun 12.

35.

Genomic profiling of collaborative cross founder mice infected with respiratory viruses reveals novel transcripts and infection-related strain-specific gene and isoform expression.

Xiong H, Morrison J, Ferris MT, Gralinski LE, Whitmore AC, Green R, Thomas MJ, Tisoncik-Go J, Schroth GP, Pardo-Manuel de Villena F, Baric RS, Heise MT, Peng X, Katze MG.

G3 (Bethesda). 2014 Jun 5;4(8):1429-44. doi: 10.1534/g3.114.011759.

36.

Deep sequencing of HIV-infected cells: insights into nascent transcription and host-directed therapy.

Peng X, Sova P, Green RR, Thomas MJ, Korth MJ, Proll S, Xu J, Cheng Y, Yi K, Chen L, Peng Z, Wang J, Palermo RE, Katze MG.

J Virol. 2014 Aug;88(16):8768-82. doi: 10.1128/JVI.00768-14. Epub 2014 May 21.

37.

Pathogenic influenza viruses and coronaviruses utilize similar and contrasting approaches to control interferon-stimulated gene responses.

Menachery VD, Eisfeld AJ, Schäfer A, Josset L, Sims AC, Proll S, Fan S, Li C, Neumann G, Tilton SC, Chang J, Gralinski LE, Long C, Green R, Williams CM, Weiss J, Matzke MM, Webb-Robertson BJ, Schepmoes AA, Shukla AK, Metz TO, Smith RD, Waters KM, Katze MG, Kawaoka Y, Baric RS.

MBio. 2014 May 20;5(3):e01174-14. doi: 10.1128/mBio.01174-14.

38.

Assessment and improvement of Indian-origin rhesus macaque and Mauritian-origin cynomolgus macaque genome annotations using deep transcriptome sequencing data.

Peng X, Pipes L, Xiong H, Green RR, Jones DC, Ruzzo WL, Schroth GP, Mason CE, Palermo RE, Katze MG.

J Med Primatol. 2014 Oct;43(5):317-28. doi: 10.1111/jmp.12125. Epub 2014 May 8.

39.

Deep transcriptional sequencing of mucosal challenge compartment from rhesus macaques acutely infected with simian immunodeficiency virus implicates loss of cell adhesion preceding immune activation.

Barrenas F, Palermo RE, Agricola B, Agy MB, Aicher L, Carter V, Flanary L, Green RR, McLain R, Li Q, Lu W, Murnane R, Peng X, Thomas MJ, Weiss JM, Anderson DM, Katze MG.

J Virol. 2014 Jul;88(14):7962-72. doi: 10.1128/JVI.00543-14. Epub 2014 May 7.

41.

Attenuation and restoration of severe acute respiratory syndrome coronavirus mutant lacking 2'-o-methyltransferase activity.

Menachery VD, Yount BL Jr, Josset L, Gralinski LE, Scobey T, Agnihothram S, Katze MG, Baric RS.

J Virol. 2014 Apr;88(8):4251-64. doi: 10.1128/JVI.03571-13. Epub 2014 Jan 29.

42.

Advancing the high throughput identification of liver fibrosis protein signatures using multiplexed ion mobility spectrometry.

Baker ES, Burnum-Johnson KE, Jacobs JM, Diamond DL, Brown RN, Ibrahim YM, Orton DJ, Piehowski PD, Purdy DE, Moore RJ, Danielson WF 3rd, Monroe ME, Crowell KL, Slysz GW, Gritsenko MA, Sandoval JD, Lamarche BL, Matzke MM, Webb-Robertson BJ, Simons BC, McMahon BJ, Bhattacharya R, Perkins JD, Carithers RL Jr, Strom S, Self SG, Katze MG, Anderson GA, Smith RD.

Mol Cell Proteomics. 2014 Apr;13(4):1119-27. doi: 10.1074/mcp.M113.034595. Epub 2014 Jan 8.

43.

A comprehensive collection of systems biology data characterizing the host response to viral infection.

Aevermann BD, Pickett BE, Kumar S, Klem EB, Agnihothram S, Askovich PS, Bankhead A 3rd, Bolles M, Carter V, Chang J, Clauss TR, Dash P, Diercks AH, Eisfeld AJ, Ellis A, Fan S, Ferris MT, Gralinski LE, Green RR, Gritsenko MA, Hatta M, Heegel RA, Jacobs JM, Jeng S, Josset L, Kaiser SM, Kelly S, Law GL, Li C, Li J, Long C, Luna ML, Matzke M, McDermott J, Menachery V, Metz TO, Mitchell H, Monroe ME, Navarro G, Neumann G, Podyminogin RL, Purvine SO, Rosenberger CM, Sanders CJ, Schepmoes AA, Shukla AK, Sims A, Sova P, Tam VC, Tchitchek N, Thomas PG, Tilton SC, Totura A, Wang J, Webb-Robertson BJ, Wen J, Weiss JM, Yang F, Yount B, Zhang Q, McWeeney S, Smith RD, Waters KM, Kawaoka Y, Baric R, Aderem A, Katze MG, Scheuermann RH.

Sci Data. 2014 Oct 14;1:140033. doi: 10.1038/sdata.2014.33. eCollection 2014.

44.

Old world monkeys and new age science: the evolution of nonhuman primate systems virology.

Palermo RE, Tisoncik-Go J, Korth MJ, Katze MG.

ILAR J. 2013;54(2):166-80. doi: 10.1093/ilar/ilt039. Review.

45.

Middle East respiratory syndrome coronavirus (MERS-CoV) causes transient lower respiratory tract infection in rhesus macaques.

de Wit E, Rasmussen AL, Falzarano D, Bushmaker T, Feldmann F, Brining DL, Fischer ER, Martellaro C, Okumura A, Chang J, Scott D, Benecke AG, Katze MG, Feldmann H, Munster VJ.

Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16598-603. doi: 10.1073/pnas.1310744110. Epub 2013 Sep 23.

46.

Treatment with interferon-α2b and ribavirin improves outcome in MERS-CoV-infected rhesus macaques.

Falzarano D, de Wit E, Rasmussen AL, Feldmann F, Okumura A, Scott DP, Brining D, Bushmaker T, Martellaro C, Baseler L, Benecke AG, Katze MG, Munster VJ, Feldmann H.

Nat Med. 2013 Oct;19(10):1313-7. doi: 10.1038/nm.3362. Epub 2013 Sep 8.

47.

Drug repurposing: a better approach for infectious disease drug discovery?

Law GL, Tisoncik-Go J, Korth MJ, Katze MG.

Curr Opin Immunol. 2013 Oct;25(5):588-92. doi: 10.1016/j.coi.2013.08.004. Epub 2013 Sep 5. Review.

48.

A network integration approach to predict conserved regulators related to pathogenicity of influenza and SARS-CoV respiratory viruses.

Mitchell HD, Eisfeld AJ, Sims AC, McDermott JE, Matzke MM, Webb-Robertson BJ, Tilton SC, Tchitchek N, Josset L, Li C, Ellis AL, Chang JH, Heegel RA, Luna ML, Schepmoes AA, Shukla AK, Metz TO, Neumann G, Benecke AG, Smith RD, Baric RS, Kawaoka Y, Katze MG, Waters KM.

PLoS One. 2013 Jul 25;8(7):e69374. doi: 10.1371/journal.pone.0069374. Print 2013.

49.

Mechanisms of severe acute respiratory syndrome coronavirus-induced acute lung injury.

Gralinski LE, Bankhead A 3rd, Jeng S, Menachery VD, Proll S, Belisle SE, Matzke M, Webb-Robertson BJ, Luna ML, Shukla AK, Ferris MT, Bolles M, Chang J, Aicher L, Waters KM, Smith RD, Metz TO, Law GL, Katze MG, McWeeney S, Baric RS.

MBio. 2013 Aug 6;4(4). pii: e00271-13. doi: 10.1128/mBio.00271-13.

50.

Mathematical models of viral latency.

Selinger C, Katze MG.

Curr Opin Virol. 2013 Aug;3(4):402-7. doi: 10.1016/j.coviro.2013.06.015. Epub 2013 Jul 26. Review.

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