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Items: 1 to 50 of 220

1.

Heme Oxygenase-2 Protects Against Ischemic Acute Kidney Injury: The Influence of Age and Sex.

Nath KA, Garovic VD, Grande JP, Croatt AJ, Ackerman AW, Farrugia G, Katusic ZS, Belcher JD, Vercellotti GM.

Am J Physiol Renal Physiol. 2019 Jun 19. doi: 10.1152/ajprenal.00085.2019. [Epub ahead of print]

PMID:
31215802
2.

Vascular phenotype of amyloid precursor protein-deficient mice.

d'Uscio LV, Katusic ZS.

Am J Physiol Heart Circ Physiol. 2019 Jun 1;316(6):H1297-H1308. doi: 10.1152/ajpheart.00539.2018. Epub 2019 Mar 22.

PMID:
30901278
3.

Vascular dysfunction-The disregarded partner of Alzheimer's disease.

Sweeney MD, Montagne A, Sagare AP, Nation DA, Schneider LS, Chui HC, Harrington MG, Pa J, Law M, Wang DJJ, Jacobs RE, Doubal FN, Ramirez J, Black SE, Nedergaard M, Benveniste H, Dichgans M, Iadecola C, Love S, Bath PM, Markus HS, Salman RA, Allan SM, Quinn TJ, Kalaria RN, Werring DJ, Carare RO, Touyz RM, Williams SCR, Moskowitz MA, Katusic ZS, Lutz SE, Lazarov O, Minshall RD, Rehman J, Davis TP, Wellington CL, González HM, Yuan C, Lockhart SN, Hughes TM, Chen CLH, Sachdev P, O'Brien JT, Skoog I, Pantoni L, Gustafson DR, Biessels GJ, Wallin A, Smith EE, Mok V, Wong A, Passmore P, Barkof F, Muller M, Breteler MMB, Román GC, Hamel E, Seshadri S, Gottesman RF, van Buchem MA, Arvanitakis Z, Schneider JA, Drewes LR, Hachinski V, Finch CE, Toga AW, Wardlaw JM, Zlokovic BV.

Alzheimers Dement. 2019 Jan;15(1):158-167. doi: 10.1016/j.jalz.2018.07.222.

4.

Partial loss of endothelial nitric oxide leads to increased cerebrovascular beta amyloid.

Austin SA, Katusic ZS.

J Cereb Blood Flow Metab. 2019 Jan 7:271678X18822474. doi: 10.1177/0271678X18822474. [Epub ahead of print]

PMID:
30614363
5.

The murine dialysis fistula model exhibits a senescence phenotype: pathobiological mechanisms and therapeutic potential.

Nath KA, O'Brien DR, Croatt AJ, Grande JP, Ackerman AW, Nath MC, Yamada S, Terzic A, Tchkonia T, Kirkland JL, Katusic ZS.

Am J Physiol Renal Physiol. 2018 Nov 1;315(5):F1493-F1499. doi: 10.1152/ajprenal.00308.2018. Epub 2018 Jul 18.

PMID:
30019935
6.

Effects of Brain-Derived Neurotrophic Factor on MicroRNA Expression Profile in Human Endothelial Progenitor Cells.

He T, Sun R, Li Y, Katusic ZS.

Cell Transplant. 2018 Jun;27(6):1005-1009. doi: 10.1177/0963689718761658. Epub 2018 Jun 4.

7.
8.

Impairment of amyloid precursor protein alpha-processing in cerebral microvessels of type 1 diabetic mice.

He T, Sun R, Santhanam AV, d'Uscio LV, Lu T, Katusic ZS.

J Cereb Blood Flow Metab. 2019 Jun;39(6):1085-1098. doi: 10.1177/0271678X17746981. Epub 2017 Dec 18.

PMID:
29251519
9.

Role of TLR4 signaling in the nephrotoxicity of heme and heme proteins.

Nath KA, Belcher JD, Nath MC, Grande JP, Croatt AJ, Ackerman AW, Katusic ZS, Vercellotti GM.

Am J Physiol Renal Physiol. 2018 May 1;314(5):F906-F914. doi: 10.1152/ajprenal.00432.2017. Epub 2017 Oct 4.

10.

Endothelium-specific amyloid precursor protein deficiency causes endothelial dysfunction in cerebral arteries.

d'Uscio LV, He T, Santhanam AV, Katusic ZS.

J Cereb Blood Flow Metab. 2018 Oct;38(10):1715-1726. doi: 10.1177/0271678X17735418. Epub 2017 Sep 29.

PMID:
28959912
11.

Role of the endothelial caveolae microdomain in shear stress-mediated coronary vasorelaxation.

Lu T, Wang XL, Chai Q, Sun X, Sieck GC, Katusic ZS, Lee HC.

J Biol Chem. 2017 Nov 17;292(46):19013-19023. doi: 10.1074/jbc.M117.786152. Epub 2017 Sep 18.

12.

Endothelin-A Receptor Antagonism Retards the Progression of Murine Sickle Cell Nephropathy.

Nath KA, Katusic ZS.

J Am Soc Nephrol. 2017 Aug;28(8):2253-2255. doi: 10.1681/ASN.2017030320. Epub 2017 Apr 25. No abstract available.

13.

BH4-Mediated Enhancement of Endothelial Nitric Oxide Synthase Activity Reduces Hyperoxia-Induced Endothelial Damage and Preserves Vascular Integrity in the Neonate.

Edgar KS, Galvin OM, Collins A, Katusic ZS, McDonald DM.

Invest Ophthalmol Vis Sci. 2017 Jan 1;58(1):230-241. doi: 10.1167/iovs.16-20523.

14.

Expression and Processing of Amyloid Precursor Protein in Vascular Endothelium.

d'Uscio LV, He T, Katusic ZS.

Physiology (Bethesda). 2017 Jan;32(1):20-32. Review.

15.
16.

Predicting the Functionality and Form of a Dialysis Fistula.

Nath KA, Katusic ZS.

J Am Soc Nephrol. 2016 Dec;27(12):3508-3510. Epub 2016 Aug 4. No abstract available.

17.

Neurovascular Protective Function of Endothelial Nitric Oxide - Recent Advances.

Katusic ZS, Austin SA.

Circ J. 2016 Jun 24;80(7):1499-503. doi: 10.1253/circj.CJ-16-0423. Epub 2016 May 25. Review.

18.

A new model of an arteriovenous fistula in chronic kidney disease in the mouse: beneficial effects of upregulated heme oxygenase-1.

Kang L, Grande JP, Hillestad ML, Croatt AJ, Barry MA, Katusic ZS, Nath KA.

Am J Physiol Renal Physiol. 2016 Mar 15;310(6):F466-76. doi: 10.1152/ajprenal.00288.2015. Epub 2015 Dec 16.

19.

Role of prostacyclin signaling in endothelial production of soluble amyloid precursor protein-α in cerebral microvessels.

He T, Santhanam AV, Lu T, d'Uscio LV, Katusic ZS.

J Cereb Blood Flow Metab. 2017 Jan;37(1):106-122. Epub 2015 Nov 20.

20.

Regional Heterogeneity of Cerebral Microvessels and Brain Susceptibility to Oxidative Stress.

Austin SA, Santhanam AV, d'Uscio LV, Katusic ZS.

PLoS One. 2015 Dec 2;10(12):e0144062. doi: 10.1371/journal.pone.0144062. eCollection 2015.

21.

Characterization of cerebral microvasculature in transgenic mice with endothelium targeted over-expression of GTP-cyclohydrolase I.

Santhanam AV, d'Uscio LV, Katusic ZS.

Brain Res. 2015 Nov 2;1625:198-205. doi: 10.1016/j.brainres.2015.08.034. Epub 2015 Sep 3.

22.

Uncoupling of endothelial nitric oxide synthase in cerebral vasculature of Tg2576 mice.

Santhanam AV, d'Uscio LV, He T, Das P, Younkin SG, Katusic ZS.

J Neurochem. 2015 Sep;134(6):1129-38. doi: 10.1111/jnc.13205. Epub 2015 Jul 15.

23.

Hyperoxia depletes (6R)-5,6,7,8-tetrahydrobiopterin levels in the neonatal retina: implications for nitric oxide synthase function in retinopathy.

Edgar KS, Matesanz N, Gardiner TA, Katusic ZS, McDonald DM.

Am J Pathol. 2015 Jun;185(6):1769-82. doi: 10.1016/j.ajpath.2015.02.021. Epub 2015 Apr 23.

PMID:
25913075
24.

Induction and functional significance of the heme oxygenase system in pathological shear stress in vivo.

Kang L, Hillestad ML, Grande JP, Croatt AJ, Barry MA, Farrugia G, Katusic ZS, Nath KA.

Am J Physiol Heart Circ Physiol. 2015 Jun 1;308(11):H1402-13. doi: 10.1152/ajpheart.00882.2014. Epub 2015 Mar 27.

25.

Erythropoietin prevents endothelial dysfunction in GTP-cyclohydrolase I-deficient hph1 mice.

dʼUscio LV, Santhanam AV, Katusic ZS.

J Cardiovasc Pharmacol. 2014 Dec;64(6):514-21. doi: 10.1097/FJC.0000000000000145.

26.

Erythropoietin increases bioavailability of tetrahydrobiopterin and protects cerebral microvasculature against oxidative stress induced by eNOS uncoupling.

Santhanam AV, d'Uscio LV, Katusic ZS.

J Neurochem. 2014 Nov;131(4):521-9. doi: 10.1111/jnc.12824. Epub 2014 Aug 6.

27.

Mechanisms of vascular dysfunction in mice with endothelium-specific deletion of the PPAR-δ gene.

d'Uscio LV, He T, Santhanam AV, Tai LJ, Evans RM, Katusic ZS.

Am J Physiol Heart Circ Physiol. 2014 Apr 1;306(7):H1001-10. doi: 10.1152/ajpheart.00761.2013. Epub 2014 Jan 31.

28.

Endothelial nitric oxide: protector of a healthy mind.

Katusic ZS, Austin SA.

Eur Heart J. 2014 Apr;35(14):888-94. doi: 10.1093/eurheartj/eht544. Epub 2013 Dec 18. Review.

29.

Endothelial nitric oxide deficiency promotes Alzheimer's disease pathology.

Austin SA, Santhanam AV, Hinton DJ, Choi DS, Katusic ZS.

J Neurochem. 2013 Dec;127(5):691-700. doi: 10.1111/jnc.12334. Epub 2013 Jun 27.

30.

Functioning of an arteriovenous fistula requires heme oxygenase-2.

Kang L, Grande JP, Farrugia G, Croatt AJ, Katusic ZS, Nath KA.

Am J Physiol Renal Physiol. 2013 Aug 15;305(4):F545-52. doi: 10.1152/ajprenal.00234.2013. Epub 2013 May 15.

31.

Age sensitizes the kidney to heme protein-induced acute kidney injury.

Nath KA, Grande JP, Farrugia G, Croatt AJ, Belcher JD, Hebbel RP, Vercellotti GM, Katusic ZS.

Am J Physiol Renal Physiol. 2013 Feb 1;304(3):F317-25. doi: 10.1152/ajprenal.00606.2012. Epub 2012 Nov 28.

32.

Increased production of superoxide anion contributes to dysfunction of the arteriovenous fistula.

Tsapenko MV, d'Uscio LV, Grande JP, Croatt AJ, Hernandez MC, Ackerman AW, Katusic ZS, Nath KA.

Am J Physiol Renal Physiol. 2012 Dec 15;303(12):F1601-7. doi: 10.1152/ajprenal.00449.2012. Epub 2012 Sep 19.

33.

PPARδ agonist GW501516 prevents uncoupling of endothelial nitric oxide synthase in cerebral microvessels of hph-1 mice.

Santhanam AV, d'Uscio LV, He T, Katusic ZS.

Brain Res. 2012 Nov 5;1483:89-95. doi: 10.1016/j.brainres.2012.09.012. Epub 2012 Sep 13.

34.

Activation of PPARδ prevents endothelial dysfunction induced by overexpression of amyloid-β precursor protein.

d'Uscio LV, Das P, Santhanam AV, He T, Younkin SG, Katusic ZS.

Cardiovasc Res. 2012 Dec 1;96(3):504-12. doi: 10.1093/cvr/cvs266. Epub 2012 Aug 10.

35.

Supplementation of nitric oxide attenuates AβPP and BACE1 protein in cerebral microcirculation of eNOS-deficient mice.

Austin SA, d'Uscio LV, Katusic ZS.

J Alzheimers Dis. 2013;33(1):29-33. doi: 10.3233/JAD-2012-121351.

36.

Uncoupling of eNOS causes superoxide anion production and impairs NO signaling in the cerebral microvessels of hph-1 mice.

Santhanam AV, d'Uscio LV, Smith LA, Katusic ZS.

J Neurochem. 2012 Sep;122(6):1211-8. doi: 10.1111/j.1471-4159.2012.07872.x. Epub 2012 Aug 3.

37.

Vascular effects of prostacyclin: does activation of PPARδ play a role?

Katusic ZS, Santhanam AV, He T.

Trends Pharmacol Sci. 2012 Oct;33(10):559-64. doi: 10.1016/j.tips.2012.05.005. Epub 2012 Jun 23. Review.

38.

Reactive oxygen species signaling facilitates FOXO-3a/FBXO-dependent vascular BK channel β1 subunit degradation in diabetic mice.

Lu T, Chai Q, Yu L, d'Uscio LV, Katusic ZS, He T, Lee HC.

Diabetes. 2012 Jul;61(7):1860-8. doi: 10.2337/db11-1658. Epub 2012 May 14.

39.

Astrocytic high-mobility group box 1 promotes endothelial progenitor cell-mediated neurovascular remodeling during stroke recovery.

Hayakawa K, Pham LD, Katusic ZS, Arai K, Lo EH.

Proc Natl Acad Sci U S A. 2012 May 8;109(19):7505-10. doi: 10.1073/pnas.1121146109. Epub 2012 Apr 23.

40.

Vasculature and kidney complications in sickle cell disease.

Nath KA, Katusic ZS.

J Am Soc Nephrol. 2012 May;23(5):781-4. doi: 10.1681/ASN.2011101019. Epub 2012 Mar 22.

41.

Brain-derived neurotrophic factor increases expression of MnSOD in human circulating angiogenic cells.

He T, Katusic ZS.

Microvasc Res. 2012 May;83(3):366-71. doi: 10.1016/j.mvr.2012.01.001. Epub 2012 Jan 9.

42.

Differential effects of eNOS uncoupling on conduit and small arteries in GTP-cyclohydrolase I-deficient hph-1 mice.

d'Uscio LV, Smith LA, Katusic ZS.

Am J Physiol Heart Circ Physiol. 2011 Dec;301(6):H2227-34. doi: 10.1152/ajpheart.00588.2011. Epub 2011 Sep 30.

43.

Activation of peroxisome proliferator-activated receptor-{delta} enhances regenerative capacity of human endothelial progenitor cells by stimulating biosynthesis of tetrahydrobiopterin.

He T, Smith LA, Lu T, Joyner MJ, Katusic ZS.

Hypertension. 2011 Aug;58(2):287-94. doi: 10.1161/HYPERTENSIONAHA.111.172189. Epub 2011 Jun 27.

44.

Regional and systemic hemodynamic responses following the creation of a murine arteriovenous fistula.

Kang L, Yamada S, Hernandez MC, Croatt AJ, Grande JP, Juncos JP, Vercellotti GM, Hebbel RP, Katusic ZS, Terzic A, Nath KA.

Am J Physiol Renal Physiol. 2011 Oct;301(4):F845-51. doi: 10.1152/ajprenal.00311.2011. Epub 2011 Jun 22.

45.

Reduced proliferation of aged human vascular smooth muscle cells--role of oxygen-derived free radicals and BubR1 expression.

Guntani A, Matsumoto T, Kyuragi R, Iwasa K, Onohara T, Itoh H, Katusic ZS, Maehara Y.

J Surg Res. 2011 Sep;170(1):143-9. doi: 10.1016/j.jss.2011.03.024. Epub 2011 Apr 8.

PMID:
21550059
46.

Antihypertensive therapy increases tetrahydrobiopterin levels and NO/cGMP signaling in small arteries of angiotensin II-infused hypertensive rats.

Kang KT, Sullivan JC, Spradley FT, d'Uscio LV, Katusic ZS, Pollock JS.

Am J Physiol Heart Circ Physiol. 2011 Mar;300(3):H718-24. doi: 10.1152/ajpheart.00393.2010. Epub 2010 Dec 10.

47.

Endothelial nitric oxide modulates expression and processing of amyloid precursor protein.

Austin SA, Santhanam AV, Katusic ZS.

Circ Res. 2010 Dec 10;107(12):1498-502. doi: 10.1161/CIRCRESAHA.110.233080. Epub 2010 Dec 2.

48.

MCP-1 contributes to arteriovenous fistula failure.

Juncos JP, Grande JP, Kang L, Ackerman AW, Croatt AJ, Katusic ZS, Nath KA.

J Am Soc Nephrol. 2011 Jan;22(1):43-8. doi: 10.1681/ASN.2010040373. Epub 2010 Nov 29.

49.

Selective enhancement of contractions to α1-adrenergic receptor activation in the aorta of mice with sickle cell disease.

Juncos R, Juncos L, Hebbel RP, Vercellotti GM, Katusic ZS, Nath KA.

J Cardiovasc Pharmacol. 2011 Feb;57(2):263-6. doi: 10.1097/FJC.0b013e318204bb34.

50.

Cardiovascular effects of erythropoietin an update.

Santhanam AV, d'Uscio LV, Katusic ZS.

Adv Pharmacol. 2010;60:257-85. doi: 10.1016/B978-0-12-385061-4.00009-X. Review.

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