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Items: 33


Erythrocyte and plasma oxidative stress appears to be compensated in patients with sickle cell disease during a period of relative health, despite the presence of known oxidative agents.

Detterich JA, Liu H, Suriany S, Kato RM, Chalacheva P, Tedla B, Shah PM, Khoo MC, Wood JC, Coates TD, Milne GL, Oh JY, Patel RP, Forman HJ.

Free Radic Biol Med. 2019 Sep;141:408-415. doi: 10.1016/j.freeradbiomed.2019.07.004. Epub 2019 Jul 3.


Sickle Cell Disease Subjects Have a Distinct Abnormal Autonomic Phenotype Characterized by Peripheral Vasoconstriction With Blunted Cardiac Response to Head-Up Tilt.

Chalacheva P, Kato RM, Shah P, Veluswamy S, Denton CC, Sunwoo J, Thuptimdang W, Wood JC, Detterich JA, Coates TD, Khoo MCK.

Front Physiol. 2019 Apr 11;10:381. doi: 10.3389/fphys.2019.00381. eCollection 2019.


Mental stress causes vasoconstriction in subjects with sickle cell disease and in normal controls.

Shah P, Khaleel M, Thuptimdang W, Sunwoo J, Veluswamy S, Chalacheva P, Kato RM, Detterich J, Wood JC, Zeltzer L, Sposto R, Khoo MCK, Coates TD.

Haematologica. 2020 Jan;105(1):83-90. doi: 10.3324/haematol.2018.211391. Epub 2019 Apr 11.


Early Use of Anti-influenza Medications in Hospitalized Children With Tracheostomy.

Miyakawa R, Barreto NB, Kato RM, Neely MN, Russell CJ.

Pediatrics. 2019 Mar;143(3). pii: e20182608. doi: 10.1542/peds.2018-2608.


Upper Airway Narrowing during Central Apnea in Obese Adolescents.

Kato RM, Kim YC, Joshi B, Loloyan S, Wee CP, Wu Z, Tran WH, Keens TG, Khoo MCK, Nayak KS, Davidson Ward SL.

Ann Am Thorac Soc. 2018 Dec;15(12):1465-1471. doi: 10.1513/AnnalsATS.201806-412OC.


A novel cross-correlation methodology for assessing biophysical responses associated with pain.

Sunwoo J, Chalacheva P, Khaleel M, Shah P, Sposto R, Kato RM, Detterich J, Zeltzer LK, Wood JC, Coates TD, Khoo MC.

J Pain Res. 2018 Oct 5;11:2207-2219. doi: 10.2147/JPR.S142582. eCollection 2018.


A Retrospective Review of Infants Receiving Sildenafil.

De A, Shah P, Szmuszkovicz J, Bhombal S, Azen S, Kato RM.

J Pediatr Pharmacol Ther. 2018 Mar-Apr;23(2):100-105. doi: 10.5863/1551-6776-23.2.100.


Facial and Nasolabial Aesthetics of Complete UCLP Submitted to 2-Stage Palate Repair With Vomer Flap.

Ozawa TO, Reis LLS, Kato RM, Rocha DL, Sathler R, Garib DG.

Cleft Palate Craniofac J. 2018 Oct;55(9):1211-1217. doi: 10.1177/1055665618767418. Epub 2018 Apr 13.


Individuals with sickle cell disease have a significantly greater vasoconstriction response to thermal pain than controls and have significant vasoconstriction in response to anticipation of pain.

Khaleel M, Puliyel M, Shah P, Sunwoo J, Kato RM, Chalacheva P, Thuptimdang W, Detterich J, Wood JC, Tsao J, Zeltzer L, Sposto R, Khoo MCK, Coates TD.

Am J Hematol. 2017 Nov;92(11):1137-1145. doi: 10.1002/ajh.24858. Epub 2017 Aug 17.


Biophysical markers of the peripheral vasoconstriction response to pain in sickle cell disease.

Chalacheva P, Khaleel M, Sunwoo J, Shah P, Detterich JA, Kato RM, Thuptimdang W, Meiselman HJ, Sposto R, Tsao J, Wood JC, Zeltzer L, Coates TD, Khoo MCK.

PLoS One. 2017 May 24;12(5):e0178353. doi: 10.1371/journal.pone.0178353. eCollection 2017.


Risk of developing palatally displaced canines in patients with early detectable dental anomalies: a retrospective cohort study.

Garib DG, Lancia M, Kato RM, Oliveira TM, Neves LT.

J Appl Oral Sci. 2016 Nov-Dec;24(6):549-554. doi: 10.1590/1678-775720150535.


Empirical model of human blood transverse relaxation at 3‚ÄČT improves MRI T2 oximetry.

Bush A, Borzage M, Detterich J, Kato RM, Meiselman HJ, Coates T, Wood JC.

Magn Reson Med. 2017 Jun;77(6):2364-2371. doi: 10.1002/mrm.26311. Epub 2016 Jul 6.


A physician survey reveals differences in management of idiopathic pulmonary hemosiderosis.

Chin CI, Kohn SL, Keens TG, Margetis MF, Kato RM.

Orphanet J Rare Dis. 2015 Aug 20;10:98. doi: 10.1186/s13023-015-0319-5.


Autonomic responses to cold face stimulation in sickle cell disease: a time-varying model analysis.

Chalacheva P, Kato RM, Sangkatumvong S, Detterich J, Bush A, Wood JC, Meiselman H, Coates TD, Khoo MC.

Physiol Rep. 2015 Jul 14;3(7). pii: e12463. doi: 10.14814/phy2.12463. Epub 2015 Jul 14.


Chronic transfusion therapy improves but does not normalize systemic and pulmonary vasculopathy in sickle cell disease.

Detterich JA, Kato RM, Rabai M, Meiselman HJ, Coates TD, Wood JC.

Blood. 2015 Aug 6;126(6):703-10. doi: 10.1182/blood-2014-12-614370. Epub 2015 Jun 2.


A diagnosis of exclusion: a 3-year-old boy with respiratory distress and anemia.

McCaffrey Cosimini MJ, Molas-Torreblanca K, Kato RM, Loloyan S, Ramanathan A.

Hosp Pediatr. 2013 Oct;3(4):377-80. doi: 10.1542/hpeds.2013-0003. No abstract available.


Protein kinase C betaII regulates Akt phosphorylation on Ser-473 in a cell type- and stimulus-specific fashion.

Kawakami Y, Nishimoto H, Kitaura J, Maeda-Yamamoto M, Kato RM, Littman DR, Leitges M, Rawlings DJ, Kawakami T.

J Biol Chem. 2004 Nov 12;279(46):47720-5. Epub 2004 Sep 9. Erratum in: J Biol Chem. 2005 Mar 4;280(9):8628.


Tec kinases mediate sustained calcium influx via site-specific tyrosine phosphorylation of the phospholipase Cgamma Src homology 2-Src homology 3 linker.

Humphries LA, Dangelmaier C, Sommer K, Kipp K, Kato RM, Griffith N, Bakman I, Turk CW, Daniel JL, Rawlings DJ.

J Biol Chem. 2004 Sep 3;279(36):37651-61. Epub 2004 Jun 7.


Sustained correction of B-cell development and function in a murine model of X-linked agammaglobulinemia (XLA) using retroviral-mediated gene transfer.

Yu PW, Tabuchi RS, Kato RM, Astrakhan A, Humblet-Baron S, Kipp K, Chae K, Ellmeier W, Witte ON, Rawlings DJ.

Blood. 2004 Sep 1;104(5):1281-90. Epub 2004 May 13.


A Ras activation pathway dependent on Syk phosphorylation of protein kinase C.

Kawakami Y, Kitaura J, Yao L, McHenry RW, Kawakami Y, Newton AC, Kang S, Kato RM, Leitges M, Rawlings DJ, Kawakami T.

Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9470-5. Epub 2003 Jul 24.


PKC-beta controls I kappa B kinase lipid raft recruitment and activation in response to BCR signaling.

Su TT, Guo B, Kawakami Y, Sommer K, Chae K, Humphries LA, Kato RM, Kang S, Patrone L, Wall R, Teitell M, Leitges M, Kawakami T, Rawlings DJ.

Nat Immunol. 2002 Aug;3(8):780-6. Epub 2002 Jul 15.


PKCbeta modulates antigen receptor signaling via regulation of Btk membrane localization.

Kang SW, Wahl MI, Chu J, Kitaura J, Kawakami Y, Kato RM, Tabuchi R, Tarakhovsky A, Kawakami T, Turck CW, Witte ON, Rawlings DJ.

EMBO J. 2001 Oct 15;20(20):5692-702.


Engagement of the human pre-B cell receptor generates a lipid raft-dependent calcium signaling complex.

Guo B, Kato RM, Garcia-Lloret M, Wahl MI, Rawlings DJ.

Immunity. 2000 Aug;13(2):243-53.


Redundant and opposing functions of two tyrosine kinases, Btk and Lyn, in mast cell activation.

Kawakami Y, Kitaura J, Satterthwaite AB, Kato RM, Asai K, Hartman SE, Maeda-Yamamoto M, Lowell CA, Rawlings DJ, Witte ON, Kawakami T.

J Immunol. 2000 Aug 1;165(3):1210-9.


Hydroxychloroquine inhibits calcium signals in T cells: a new mechanism to explain its immunomodulatory properties.

Goldman FD, Gilman AL, Hollenback C, Kato RM, Premack BA, Rawlings DJ.

Blood. 2000 Jun 1;95(11):3460-6.


Aberrant B cell receptor signaling from B29 (Igbeta, CD79b) gene mutations of chronic lymphocytic leukemia B cells.

Gordon MS, Kato RM, Lansigan F, Thompson AA, Wall R, Rawlings DJ.

Proc Natl Acad Sci U S A. 2000 May 9;97(10):5504-9.


In situ detection of activated Bruton's tyrosine kinase in the Ig signaling complex by phosphopeptide-specific monoclonal antibodies.

Nisitani S, Kato RM, Rawlings DJ, Witte ON, Wahl MI.

Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):2221-6.


Btk/Tec kinases regulate sustained increases in intracellular Ca2+ following B-cell receptor activation.

Fluckiger AC, Li Z, Kato RM, Wahl MI, Ochs HD, Longnecker R, Kinet JP, Witte ON, Scharenberg AM, Rawlings DJ.

EMBO J. 1998 Apr 1;17(7):1973-85.


Constitutive membrane association potentiates activation of Bruton tyrosine kinase.

Li T, Rawlings DJ, Park H, Kato RM, Witte ON, Satterthwaite AB.

Oncogene. 1997 Sep 18;15(12):1375-83.


Phosphorylation of two regulatory tyrosine residues in the activation of Bruton's tyrosine kinase via alternative receptors.

Wahl MI, Fluckiger AC, Kato RM, Park H, Witte ON, Rawlings DJ.

Proc Natl Acad Sci U S A. 1997 Oct 14;94(21):11526-33.


Activation of BTK by a phosphorylation mechanism initiated by SRC family kinases.

Rawlings DJ, Scharenberg AM, Park H, Wahl MI, Lin S, Kato RM, Fluckiger AC, Witte ON, Kinet JP.

Science. 1996 Feb 9;271(5250):822-5.


Long-term culture system for selective growth of human B-cell progenitors.

Rawlings DJ, Quan SG, Kato RM, Witte ON.

Proc Natl Acad Sci U S A. 1995 Feb 28;92(5):1570-4.


Isolation of unknown genes from human bone marrow by differential screening and single-pass cDNA sequence determination.

Orr SL, Hughes TP, Sawyers CL, Kato RM, Quan SG, Williams SP, Witte ON, Hood L.

Proc Natl Acad Sci U S A. 1994 Dec 6;91(25):11869-73.

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