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Items: 24


CCR5 status and metastatic progression in colorectal cancer.

Suarez-Carmona M, Chaorentong P, Kather JN, Rothenheber R, Ahmed A, Berthel A, Heinzelmann A, Moraleda R, Valous NA, Kosaloglu Z, Eurich R, Wolf J, Grauling-Halama S, Hundemer M, Lasitschka F, Klupp F, Kahlert C, Ulrich A, Schneider M, Falk C, Jäger D, Zoernig I, Halama N.

Oncoimmunology. 2019 Jul 13;8(9):e1626193. doi: 10.1080/2162402X.2019.1626193. eCollection 2019.


Aryl hydrocarbon receptor nuclear translocator-like (ARNTL/BMAL1) is associated with bevacizumab resistance in colorectal cancer via regulation of vascular endothelial growth factor A.

Burgermeister E, Battaglin F, Eladly F, Wu W, Herweck F, Schulte N, Betge J, Härtel N, Kather JN, Weis CA, Gaiser T, Marx A, Weiss C, Hofheinz R, Miller IS, Loupakis F, Lenz HJ, Byrne AT, Ebert MP.

EBioMedicine. 2019 Jul;45:139-154. doi: 10.1016/j.ebiom.2019.07.004. Epub 2019 Jul 9.


CD163+ immune cell infiltrates and presence of CD54+ microvessels are prognostic markers for patients with embryonal rhabdomyosarcoma.

Kather JN, Hörner C, Weis CA, Aung T, Vokuhl C, Weiss C, Scheer M, Marx A, Simon-Keller K.

Sci Rep. 2019 Jun 25;9(1):9211. doi: 10.1038/s41598-019-45551-y.


Deep learning can predict microsatellite instability directly from histology in gastrointestinal cancer.

Kather JN, Pearson AT, Halama N, Jäger D, Krause J, Loosen SH, Marx A, Boor P, Tacke F, Neumann UP, Grabsch HI, Yoshikawa T, Brenner H, Chang-Claude J, Hoffmeister M, Trautwein C, Luedde T.

Nat Med. 2019 Jul;25(7):1054-1056. doi: 10.1038/s41591-019-0462-y. Epub 2019 Jun 3.


Harnessing the innate immune system and local immunological microenvironment to treat colorectal cancer.

Kather JN, Halama N.

Br J Cancer. 2019 Apr;120(9):871-882. doi: 10.1038/s41416-019-0441-6. Epub 2019 Apr 2. Review.


High baseline soluble urokinase plasminogen activator receptor (suPAR) serum levels indicate adverse outcome after resection of pancreatic adenocarcinoma.

Loosen SH, Tacke F, Püthe N, Binneboesel M, Wiltberger G, Alizai PH, Kather JN, Paffenholz P, Ritz T, Koch A, Bergmann F, Trautwein C, Longerich T, Roderburg C, Neumann UP, Luedde T.

Carcinogenesis. 2019 Aug 22;40(8):947-955. doi: 10.1093/carcin/bgz033.


Predicting survival from colorectal cancer histology slides using deep learning: A retrospective multicenter study.

Kather JN, Krisam J, Charoentong P, Luedde T, Herpel E, Weis CA, Gaiser T, Marx A, Valous NA, Ferber D, Jansen L, Reyes-Aldasoro CC, Zörnig I, Jäger D, Brenner H, Chang-Claude J, Hoffmeister M, Halama N.

PLoS Med. 2019 Jan 24;16(1):e1002730. doi: 10.1371/journal.pmed.1002730. eCollection 2019 Jan.


Serum levels of miR-29, miR-122, miR-155 and miR-192 are elevated in patients with cholangiocarcinoma.

Loosen SH, Lurje G, Wiltberger G, Vucur M, Koch A, Kather JN, Paffenholz P, Tacke F, Ulmer FT, Trautwein C, Luedde T, Neumann UP, Roderburg C.

PLoS One. 2019 Jan 17;14(1):e0210944. doi: 10.1371/journal.pone.0210944. eCollection 2019.


Nuclear Translocation of RELB Is Increased in Diseased Human Liver and Promotes Ductular Reaction and Biliary Fibrosis in Mice.

Elßner C, Goeppert B, Longerich T, Scherr AL, Stindt J, Nanduri LK, Rupp C, Kather JN, Schmitt N, Kautz N, Breuhahn K, Ismail L, Heide D, Hetzer J, García-Beccaria M, Hövelmeyer N, Waisman A, Urbanik T, Mueller S, Gdynia G, Banales JM, Roessler S, Schirmacher P, Jäger D, Schölch S, Keitel V, Heikenwalder M, Schulze-Bergkamen H, Köhler BC.

Gastroenterology. 2019 Mar;156(4):1190-1205.e14. doi: 10.1053/j.gastro.2018.11.018. Epub 2018 Nov 13.


Topography of cancer-associated immune cells in human solid tumors.

Kather JN, Suarez-Carmona M, Charoentong P, Weis CA, Hirsch D, Bankhead P, Horning M, Ferber D, Kel I, Herpel E, Schott S, Zörnig I, Utikal J, Marx A, Gaiser T, Brenner H, Chang-Claude J, Hoffmeister M, Jäger D, Halama N.

Elife. 2018 Sep 4;7. pii: e36967. doi: 10.7554/eLife.36967.


Automatic evaluation of tumor budding in immunohistochemically stained colorectal carcinomas and correlation to clinical outcome.

Weis CA, Kather JN, Melchers S, Al-Ahmdi H, Pollheimer MJ, Langner C, Gaiser T.

Diagn Pathol. 2018 Aug 28;13(1):64. doi: 10.1186/s13000-018-0739-3.


High-Throughput Screening of Combinatorial Immunotherapies with Patient-Specific In Silico Models of Metastatic Colorectal Cancer.

Kather JN, Charoentong P, Suarez-Carmona M, Herpel E, Klupp F, Ulrich A, Schneider M, Zoernig I, Luedde T, Jaeger D, Poleszczuk J, Halama N.

Cancer Res. 2018 Sep 1;78(17):5155-5163. doi: 10.1158/0008-5472.CAN-18-1126. Epub 2018 Jul 2.


Large-scale database mining reveals hidden trends and future directions for cancer immunotherapy.

Kather JN, Berghoff AS, Ferber D, Suarez-Carmona M, Reyes-Aldasoro CC, Valous NA, Rojas-Moraleda R, Jäger D, Halama N.

Oncoimmunology. 2018 Mar 29;7(7):e1444412. doi: 10.1080/2162402X.2018.1444412. eCollection 2018.


Genomics and emerging biomarkers for immunotherapy of colorectal cancer.

Kather JN, Halama N, Jaeger D.

Semin Cancer Biol. 2018 Oct;52(Pt 2):189-197. doi: 10.1016/j.semcancer.2018.02.010. Epub 2018 Mar 1. Review.


In Silico Modeling of Immunotherapy and Stroma-Targeting Therapies in Human Colorectal Cancer.

Kather JN, Poleszczuk J, Suarez-Carmona M, Krisam J, Charoentong P, Valous NA, Weis CA, Tavernar L, Leiss F, Herpel E, Klupp F, Ulrich A, Schneider M, Marx A, Jäger D, Halama N.

Cancer Res. 2017 Nov 15;77(22):6442-6452. doi: 10.1158/0008-5472.CAN-17-2006. Epub 2017 Sep 18.


Polyphonic sonification of electrocardiography signals for diagnosis of cardiac pathologies.

Kather JN, Hermann T, Bukschat Y, Kramer T, Schad LR, Zöllner FG.

Sci Rep. 2017 Mar 20;7:44549. doi: 10.1038/srep44549.


Identification of a characteristic vascular belt zone in human colorectal cancer.

Kather JN, Zöllner FG, Schad LR, Melchers SM, Sinn HP, Marx A, Gaiser T, Weis CA.

PLoS One. 2017 Mar 2;12(3):e0171378. doi: 10.1371/journal.pone.0171378. eCollection 2017. Erratum in: PLoS One. 2017 May 8;12 (5):e0177586.


Color-coded visualization of magnetic resonance imaging multiparametric maps.

Kather JN, Weidner A, Attenberger U, Bukschat Y, Weis CA, Weis M, Schad LR, Zöllner FG.

Sci Rep. 2017 Jan 23;7:41107. doi: 10.1038/srep41107.


Multi-class texture analysis in colorectal cancer histology.

Kather JN, Weis CA, Bianconi F, Melchers SM, Schad LR, Gaiser T, Marx A, Zöllner FG.

Sci Rep. 2016 Jun 16;6:27988. doi: 10.1038/srep27988.


New Colors for Histology: Optimized Bivariate Color Maps Increase Perceptual Contrast in Histological Images.

Kather JN, Weis CA, Marx A, Schuster AK, Schad LR, Zöllner FG.

PLoS One. 2015 Dec 30;10(12):e0145572. doi: 10.1371/journal.pone.0145572. eCollection 2015.


Continuous representation of tumor microvessel density and detection of angiogenic hotspots in histological whole-slide images.

Kather JN, Marx A, Reyes-Aldasoro CC, Schad LR, Zöllner FG, Weis CA.

Oncotarget. 2015 Aug 7;6(22):19163-76.


Transgenic mouse models of corneal neovascularization: new perspectives for angiogenesis research.

Kather JN, Kroll J.

Invest Ophthalmol Vis Sci. 2014 Nov 25;55(11):7637-51. doi: 10.1167/iovs.14-15430. Review.


Angiopoietin-1 is regulated by miR-204 and contributes to corneal neovascularization in KLEIP-deficient mice.

Kather JN, Friedrich J, Woik N, Sticht C, Gretz N, Hammes HP, Kroll J.

Invest Ophthalmol Vis Sci. 2014 Jun 10;55(7):4295-303. doi: 10.1167/iovs.13-13619.


Rho guanine exchange factors in blood vessels: fine-tuners of angiogenesis and vascular function.

Kather JN, Kroll J.

Exp Cell Res. 2013 May 15;319(9):1289-97. doi: 10.1016/j.yexcr.2012.12.015. Epub 2012 Dec 21. Review.


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