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Items: 1 to 50 of 65


Simultaneous blocking of CD47 and PD-L1 increases innate and adaptive cancer immune responses and cytokine release.

Lian S, Xie R, Ye Y, Xie X, Li S, Lu Y, Li B, Cheng Y, Katanaev VL, Jia L.

EBioMedicine. 2019 Apr;42:281-295. doi: 10.1016/j.ebiom.2019.03.018. Epub 2019 Mar 14.


Towards the first targeted therapy for triple-negative breast cancer: Repositioning of clofazimine as a chemotherapy-compatible selective Wnt pathway inhibitor.

Ahmed K, Koval A, Xu J, Bodmer A, Katanaev VL.

Cancer Lett. 2019 May 1;449:45-55. doi: 10.1016/j.canlet.2019.02.018. Epub 2019 Feb 13.


A high-throughput assay pipeline for specific targeting of frizzled GPCRs in cancer.

Shaw HV, Koval A, Katanaev VL.

Methods Cell Biol. 2019;149:57-75. doi: 10.1016/bs.mcb.2018.08.006. Epub 2018 Sep 17.


Chemo-Diversification of Plant Extracts Using a Generic Bromination Reaction and Monitoring by Metabolite Profiling.

Righi D, Marcourt L, Koval A, Ducret V, Pellissier L, Mainetti A, Katanaev VL, Perron K, Wolfender JL, Queiroz EF.

ACS Comb Sci. 2019 Mar 11;21(3):171-182. doi: 10.1021/acscombsci.8b00132. Epub 2019 Jan 17.


Tannins from Syzygium guineense suppress Wnt signaling and proliferation of Wnt-dependent tumors through a direct effect on secreted Wnts.

Koval A, Pieme CA, Queiroz EF, Ragusa S, Ahmed K, Blagodatski A, Wolfender JL, Petrova TV, Katanaev VL.

Cancer Lett. 2018 Oct 28;435:110-120. doi: 10.1016/j.canlet.2018.08.003. Epub 2018 Aug 9.


Medicinal mushrooms as an attractive new source of natural compounds for future cancer therapy.

Blagodatski A, Yatsunskaya M, Mikhailova V, Tiasto V, Kagansky A, Katanaev VL.

Oncotarget. 2018 Jun 26;9(49):29259-29274. doi: 10.18632/oncotarget.25660. eCollection 2018 Jun 26. Review.


Versatility of Turing patterns potentiates rapid evolution in tarsal attachment microstructures of stick and leaf insects (Phasmatodea).

Büscher TH, Kryuchkov M, Katanaev VL, Gorb SN.

J R Soc Interface. 2018 Jun;15(143). pii: 20180281. doi: 10.1098/rsif.2018.0281.


Gαo (GNAO1) encephalopathies: plasma membrane vs. Golgi functions.

Solis GP, Katanaev VL.

Oncotarget. 2017 Oct 25;9(35):23846-23847. doi: 10.18632/oncotarget.22067. eCollection 2018 May 8. No abstract available.


Dramatic dysbalancing of the Wnt pathway in breast cancers.

Koval A, Katanaev VL.

Sci Rep. 2018 May 9;8(1):7329. doi: 10.1038/s41598-018-25672-6.


Antagonistic PCP Signaling Pathways in the developing Drosophila eye.

Katanaev VL, Egger-Adam D, Tomlinson A.

Sci Rep. 2018 Apr 10;8(1):5741. doi: 10.1038/s41598-018-24053-3.


High capacity in G protein-coupled receptor signaling.

Keshelava A, Solis GP, Hersch M, Koval A, Kryuchkov M, Bergmann S, Katanaev VL.

Nat Commun. 2018 Feb 28;9(1):876. doi: 10.1038/s41467-018-02868-y.


High-throughput targeted screening in triple-negative breast cancer cells identifies Wnt-inhibiting activities in Pacific brittle stars.

Blagodatski A, Cherepanov V, Koval A, Kharlamenko VI, Khotimchenko YS, Katanaev VL.

Sci Rep. 2017 Sep 20;7(1):11964. doi: 10.1038/s41598-017-12232-7.


Golgi-Resident Gαo Promotes Protrusive Membrane Dynamics.

Solis GP, Bilousov O, Koval A, Lüchtenborg AM, Lin C, Katanaev VL.

Cell. 2017 Sep 7;170(6):1258. doi: 10.1016/j.cell.2017.08.045. No abstract available.


Alternative moth-eye nanostructures: antireflective properties and composition of dimpled corneal nanocoatings in silk-moth ancestors.

Kryuchkov M, Lehmann J, Schaab J, Cherepanov V, Blagodatski A, Fiebig M, Katanaev VL.

J Nanobiotechnology. 2017 Sep 6;15(1):61. doi: 10.1186/s12951-017-0297-y.


Bioactive Natural Products Prioritization Using Massive Multi-informational Molecular Networks.

Olivon F, Allard PM, Koval A, Righi D, Genta-Jouve G, Neyts J, Apel C, Pannecouque C, Nothias LF, Cachet X, Marcourt L, Roussi F, Katanaev VL, Touboul D, Wolfender JL, Litaudon M.

ACS Chem Biol. 2017 Oct 20;12(10):2644-2651. doi: 10.1021/acschembio.7b00413. Epub 2017 Sep 15.


Golgi-Resident Gαo Promotes Protrusive Membrane Dynamics.

Solis GP, Bilousov O, Koval A, Lüchtenborg AM, Lin C, Katanaev VL.

Cell. 2017 Aug 24;170(5):939-955.e24. doi: 10.1016/j.cell.2017.07.015. Epub 2017 Aug 10. Erratum in: Cell. 2017 Sep 7;170(6):1258.


Antireflective nanocoatings for UV-sensation: the case of predatory owlfly insects.

Kryuchkov M, Lehmann J, Schaab J, Fiebig M, Katanaev VL.

J Nanobiotechnology. 2017 Jul 14;15(1):52. doi: 10.1186/s12951-017-0287-0.


Phosphorylation by NLK inhibits YAP-14-3-3-interactions and induces its nuclear localization.

Moon S, Kim W, Kim S, Kim Y, Song Y, Bilousov O, Kim J, Lee T, Cha B, Kim M, Kim H, Katanaev VL, Jho EH.

EMBO Rep. 2017 Jan;18(1):61-71. doi: 10.15252/embr.201642683. Epub 2016 Dec 15.


Cardamonin, a chalcone, inhibits human triple negative breast cancer cell invasiveness by downregulation of Wnt/β-catenin signaling cascades and reversal of epithelial-mesenchymal transition.

Shrivastava S, Jeengar MK, Thummuri D, Koval A, Katanaev VL, Marepally S, Naidu VGM.

Biofactors. 2017 Mar;43(2):152-169. doi: 10.1002/biof.1315. Epub 2016 Sep 1.


A Second WNT for Old Drugs: Drug Repositioning against WNT-Dependent Cancers.

Ahmed K, Shaw HV, Koval A, Katanaev VL.

Cancers (Basel). 2016 Jul 14;8(7). pii: E66. doi: 10.3390/cancers8070066. Review.


USP2-45 Is a Circadian Clock Output Effector Regulating Calcium Absorption at the Post-Translational Level.

Pouly D, Chenaux S, Martin V, Babis M, Koch R, Nagoshi E, Katanaev VL, Gachon F, Staub O.

PLoS One. 2016 Jan 12;11(1):e0145155. doi: 10.1371/journal.pone.0145155. eCollection 2016.


Inhibition of Wnt signalling and breast tumour growth by the multi-purpose drug suramin through suppression of heterotrimeric G proteins and Wnt endocytosis.

Koval A, Ahmed K, Katanaev VL.

Biochem J. 2016 Feb 15;473(4):371-81. doi: 10.1042/BJ20150913. Epub 2015 Nov 24.


Mode of interaction of the Gαo subunit of heterotrimeric G proteins with the GoLoco1 motif of Drosophila Pins is determined by guanine nucleotides.

Lüchtenborg AM, Purvanov V, Melnik BS, Becker S, Katanaev VL.

Biosci Rep. 2015 Oct 20;35(6). pii: e00271. doi: 10.1042/BSR20150201.


Diverse set of Turing nanopatterns coat corneae across insect lineages.

Blagodatski A, Sergeev A, Kryuchkov M, Lopatina Y, Katanaev VL.

Proc Natl Acad Sci U S A. 2015 Aug 25;112(34):10750-5. doi: 10.1073/pnas.1505748112. Epub 2015 Aug 11.


Reggie-1/Flotillin-2 regulates integrin trafficking and focal adhesion turnover via Rab11a.

Hülsbusch N, Solis GP, Katanaev VL, Stuermer CA.

Eur J Cell Biol. 2015 Nov;94(11):531-45. doi: 10.1016/j.ejcb.2015.07.003. Epub 2015 Jul 31.


Heterotrimeric Go protein links Wnt-Frizzled signaling with ankyrins to regulate the neuronal microtubule cytoskeleton.

Lüchtenborg AM, Solis GP, Egger-Adam D, Koval A, Lin C, Blanchard MG, Kellenberger S, Katanaev VL.

Development. 2014 Sep;141(17):3399-409. doi: 10.1242/dev.106773.


Under- and over-water halves of Gyrinidae beetle eyes harbor different corneal nanocoatings providing adaptation to the water and air environments.

Blagodatski A, Kryuchkov M, Sergeev A, Klimov AA, Shcherbakov MR, Enin GA, Katanaev VL.

Sci Rep. 2014 Aug 8;4:6004. doi: 10.1038/srep06004.


Identification of novel elements of the Drosophila blisterome sheds light on potential pathological mechanisms of several human diseases.

Bilousov O, Koval A, Keshelava A, Katanaev VL.

PLoS One. 2014 Jun 26;9(6):e101133. doi: 10.1371/journal.pone.0101133. eCollection 2014.


Double suppression of the Gα protein activity by RGS proteins.

Lin C, Koval A, Tishchenko S, Gabdulkhakov A, Tin U, Solis GP, Katanaev VL.

Mol Cell. 2014 Feb 20;53(4):663-71. doi: 10.1016/j.molcel.2014.01.014.


Role of Go/i subgroup of G proteins in olfactory signaling of Drosophila melanogaster.

Ignatious Raja JS, Katanayeva N, Katanaev VL, Galizia CG.

Eur J Neurosci. 2014 Apr;39(8):1245-55. doi: 10.1111/ejn.12481. Epub 2014 Jan 20.


Targeting the Wnt pathways for therapies.

Blagodatski A, Poteryaev D, Katanaev VL.

Mol Cell Ther. 2014 Sep 11;2:28. doi: 10.1186/2052-8426-2-28. eCollection 2014. Review.


Anti-leprosy drug clofazimine inhibits growth of triple-negative breast cancer cells via inhibition of canonical Wnt signaling.

Koval AV, Vlasov P, Shichkova P, Khunderyakova S, Markov Y, Panchenko J, Volodina A, Kondrashov FA, Katanaev VL.

Biochem Pharmacol. 2014 Feb 15;87(4):571-8. doi: 10.1016/j.bcp.2013.12.007. Epub 2013 Dec 16.


Kermit interacts with Gαo, Vang, and motor proteins in Drosophila planar cell polarity.

Lin C, Katanaev VL.

PLoS One. 2013 Oct 3;8(10):e76885. doi: 10.1371/journal.pone.0076885. eCollection 2013.


Reggies/flotillins interact with Rab11a and SNX4 at the tubulovesicular recycling compartment and function in transferrin receptor and E-cadherin trafficking.

Solis GP, Hülsbusch N, Radon Y, Katanaev VL, Plattner H, Stuermer CA.

Mol Biol Cell. 2013 Sep;24(17):2689-702. doi: 10.1091/mbc.E12-12-0854. Epub 2013 Jul 3.


Wnt secretion and gradient formation.

Solis GP, Lüchtenborg AM, Katanaev VL.

Int J Mol Sci. 2013 Mar 1;14(3):5130-45. doi: 10.3390/ijms14035130.


Crystallization and preliminary X-ray diffraction studies of Drosophila melanogaster Gαo-subunit of heterotrimeric G protein in complex with the RGS domain of CG5036.

Tishchenko S, Gabdulkhakov A, Tin U, Kostareva O, Lin C, Katanaev VL.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Jan 1;69(Pt 1):61-4. doi: 10.1107/S174430911204804X. Epub 2012 Dec 20.


Platforms for high-throughput screening of Wnt/Frizzled antagonists.

Koval A, Katanaev VL.

Drug Discov Today. 2012 Dec;17(23-24):1316-22. doi: 10.1016/j.drudis.2012.07.007. Epub 2012 Jul 20. Review.


Dual functions of DP1 promote biphasic Wnt-on and Wnt-off states during anteroposterior neural patterning.

Kim WT, Kim H, Katanaev VL, Joon Lee S, Ishitani T, Cha B, Han JK, Jho EH.

EMBO J. 2012 Aug 15;31(16):3384-97. doi: 10.1038/emboj.2012.181. Epub 2012 Jul 6.


The eye of Drosophila as a model system for studying intracellular signaling in ontogenesis and pathogenesis.

Katanaev VL, Kryuchkov MV.

Biochemistry (Mosc). 2011 Dec;76(13):1556-81. doi: 10.1134/S0006297911130116.


Role of the gene Miniature in Drosophila wing maturation.

Bilousov OO, Kozeretska IA, Katanaev VL.

Genesis. 2012 Jul;50(7):525-33. doi: 10.1002/dvg.22016. Epub 2012 Mar 9.


Analysis of micro- and nano-structures of the corneal surface of Drosophila and its mutants by atomic force microscopy and optical diffraction.

Kryuchkov M, Katanaev VL, Enin GA, Sergeev A, Timchenko AA, Serdyuk IN.

PLoS One. 2011;6(7):e22237. doi: 10.1371/journal.pone.0022237. Epub 2011 Jul 21.


Yellow submarine of the Wnt/Frizzled signaling: submerging from the G protein harbor to the targets.

Koval A, Purvanov V, Egger-Adam D, Katanaev VL.

Biochem Pharmacol. 2011 Nov 15;82(10):1311-9. doi: 10.1016/j.bcp.2011.06.005. Epub 2011 Jun 13. Review.


The Wnt/Frizzled GPCR signaling pathway.

Katanaev VL.

Biochemistry (Mosc). 2010 Dec;75(12):1428-34. Review.


Technologies of directed protein evolution in vivo.

Blagodatski A, Katanaev VL.

Cell Mol Life Sci. 2011 Apr;68(7):1207-14. doi: 10.1007/s00018-010-0610-5. Epub 2010 Dec 29. Review.


Wnt3a stimulation elicits G-protein-coupled receptor properties of mammalian Frizzled proteins.

Koval A, Katanaev VL.

Biochem J. 2011 Feb 1;433(3):435-40. doi: 10.1042/BJ20101878.


Competing activities of heterotrimeric G proteins in Drosophila wing maturation.

Katanayeva N, Kopein D, Portmann R, Hess D, Katanaev VL.

PLoS One. 2010 Aug 23;5(8):e12331. doi: 10.1371/journal.pone.0012331.


A direct and functional interaction between Go and Rab5 during G protein-coupled receptor signaling.

Purvanov V, Koval A, Katanaev VL.

Sci Signal. 2010 Aug 24;3(136):ra65. doi: 10.1126/scisignal.2000877.


Europium-labeled GTP as a general nonradioactive substitute for [(35)S]GTPgammaS in high-throughput G protein studies.

Koval A, Kopein D, Purvanov V, Katanaev VL.

Anal Biochem. 2010 Feb 15;397(2):202-7. doi: 10.1016/j.ab.2009.10.028. Epub 2009 Oct 20.


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