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Items: 44


A Multi-Institutional Cohort of Therapy-Associated Polyposis in Childhood and Young Adulthood Cancer Survivors.

Biller LH, Ukaegbu C, Dhingra TG, Burke CA, Chertock Y, Chittenden A, Church JM, Koeppe ES, Leach BH, Levinson E, Lim RM, Lutz M, Salo-Mullen E, Sheikh R, Idos G, Kastrinos F, Stoffel E, Weiss JM, Hall MJ, Kalady MF, Stadler ZK, Syngal S, Yurgelun MB.

Cancer Prev Res (Phila). 2020 Feb 12. doi: 10.1158/1940-6207.CAPR-19-0416. [Epub ahead of print]


White paper on pancreatic ductal adenocarcinoma from society of abdominal radiology's disease-focused panel for pancreatic ductal adenocarcinoma: Part II, update on imaging techniques and screening of pancreatic cancer in high-risk individuals.

Kulkarni NM, Mannelli L, Zins M, Bhosale PR, Arif-Tiwari H, Brook OR, Hecht EM, Kastrinos F, Wang ZJ, Soloff EV, Tolat PP, Sangster G, Fleming J, Tamm EP, Kambadakone AR.

Abdom Radiol (NY). 2019 Nov 25. doi: 10.1007/s00261-019-02290-y. [Epub ahead of print] Review.


Use of Family History and Genetic Testing to Determine Risk of Colorectal Cancer.

Kastrinos F, Samadder NJ, Burt RW.

Gastroenterology. 2020 Jan;158(2):389-403. doi: 10.1053/j.gastro.2019.11.029. Epub 2019 Nov 21. Review.


Management of patients with increased risk for familial pancreatic cancer: updated recommendations from the International Cancer of the Pancreas Screening (CAPS) Consortium.

Goggins M, Overbeek KA, Brand R, Syngal S, Del Chiaro M, Bartsch DK, Bassi C, Carrato A, Farrell J, Fishman EK, Fockens P, Gress TM, van Hooft JE, Hruban RH, Kastrinos F, Klein A, Lennon AM, Lucas A, Park W, Rustgi A, Simeone D, Stoffel E, Vasen HFA, Cahen DL, Canto MI, Bruno M; International Cancer of the Pancreas Screening (CAPS) consortium.

Gut. 2020 Jan;69(1):7-17. doi: 10.1136/gutjnl-2019-319352. Epub 2019 Oct 31.


Clinical Factors Associated with Urinary Tract Cancer in Individuals with Lynch Syndrome.

Wischhusen JW, Ukaegbu C, Dhingra TG, Uno H, Kastrinos F, Syngal S, Yurgelun MB.

Cancer Epidemiol Biomarkers Prev. 2020 Jan;29(1):193-199. doi: 10.1158/1055-9965.EPI-19-0213. Epub 2019 Oct 15.


Surveillance for pancreatic cancer in high-risk individuals.

Konings ICAW, Canto MI, Almario JA, Harinck F, Saxena P, Lucas AL, Kastrinos F, Whitcomb DC, Brand RE, Lachter J, Malleo G, Paiella S, Syngal S, Saltzman JR, Stoffel EM, van Hooft JE, Hruban RH, Poley JW, Fockens P, Goggins MG, Bruno MJ; International CAncer of the Pancreas Screening (CAPS) Consortium.

BJS Open. 2019 Jul 2;3(5):656-665. doi: 10.1002/bjs5.50180. eCollection 2019 Oct.


Screening for Pancreatic Cancer.

Lucas AL, Kastrinos F.

JAMA. 2019 Aug 6;322(5):407-408. doi: 10.1001/jama.2019.9690. No abstract available.


Clinical Factors Associated With Gastric Cancer in Individuals With Lynch Syndrome.

Kim J, Braun D, Ukaegbu C, Dhingra TG, Kastrinos F, Parmigiani G, Syngal S, Yurgelun MB.

Clin Gastroenterol Hepatol. 2019 Jul 15. pii: S1542-3565(19)30745-1. doi: 10.1016/j.cgh.2019.07.012. [Epub ahead of print]


Optimal Timing of Total Gastrectomy to Prevent Diffuse Gastric Cancer in Individuals with Pathogenic Variants in CDH1.

Laszkowska M, Silver E, Schrope B, Kastrinos F, Wang TC, Hur C.

Clin Gastroenterol Hepatol. 2019 Jun 18. pii: S1542-3565(19)30647-0. doi: 10.1016/j.cgh.2019.06.009. [Epub ahead of print]


Tumor Testing for Microsatellite Instability to Identify Lynch Syndrome: New Insights Into an Old Diagnostic Strategy.

Yurgelun MB, Kastrinos F.

J Clin Oncol. 2019 Feb 1;37(4):263-265. doi: 10.1200/JCO.18.01664. Epub 2018 Dec 14. No abstract available.


The Role of Genetics in Pancreatitis.

Hasan A, Moscoso DI, Kastrinos F.

Gastrointest Endosc Clin N Am. 2018 Oct;28(4):587-603. doi: 10.1016/j.giec.2018.06.001. Review.


Commentary: PREMM5 threshold of 2.5% is recommended to improve identification of PMS2 carriers.

Kastrinos F, Uno H, Syngal S.

Fam Cancer. 2018 Oct;17(4):567. doi: 10.1007/s10689-018-0074-6. No abstract available.


Community Practice Implementation of a Self-administered Version of PREMM1,2,6 to Assess Risk for Lynch Syndrome.

Luba DG, DiSario JA, Rock C, Saraiya D, Moyes K, Brown K, Rushton K, Ogara MM, Raphael M, Zimmerman D, Garrido K, Silguero E, Nelson J, Yurgelun MB, Kastrinos F, Wenstrup RJ, Syngal S.

Clin Gastroenterol Hepatol. 2018 Jan;16(1):49-58. doi: 10.1016/j.cgh.2017.06.038. Epub 2017 Jun 28.


Development and Validation of the PREMM5 Model for Comprehensive Risk Assessment of Lynch Syndrome.

Kastrinos F, Uno H, Ukaegbu C, Alvero C, McFarland A, Yurgelun MB, Kulke MH, Schrag D, Meyerhardt JA, Fuchs CS, Mayer RJ, Ng K, Steyerberg EW, Syngal S.

J Clin Oncol. 2017 Jul 1;35(19):2165-2172. doi: 10.1200/JCO.2016.69.6120. Epub 2017 May 10.


Comparison of Colonoscopy Quality Measures Across Various Practice Settings and the Impact of Performance Scorecards.

Inra JA, Nayor J, Rosenblatt M, Mutinga M, Reddy SI, Syngal S, Kastrinos F.

Dig Dis Sci. 2017 Apr;62(4):894-902. doi: 10.1007/s10620-016-4410-0. Epub 2016 Dec 19.


Comparison of Prediction Models for Lynch Syndrome Among Individuals With Colorectal Cancer.

Kastrinos F, Ojha RP, Leenen C, Alvero C, Mercado RC, Balmaña J, Valenzuela I, Balaguer F, Green R, Lindor NM, Thibodeau SN, Newcomb P, Win AK, Jenkins M, Buchanan DD, Bertario L, Sala P, Hampel H, Syngal S, Steyerberg EW; Lynch Syndrome prediction model validation study group.

J Natl Cancer Inst. 2015 Nov 18;108(2). pii: djv308. doi: 10.1093/jnci/djv308. Print 2016 Feb.


Family matters in lynch syndrome.

Kastrinos F, Steyerberg EW.

J Natl Cancer Inst. 2015 Mar 20;107(4). pii: djv050. doi: 10.1093/jnci/djv050. Print 2015 Apr. No abstract available.


Racial variation in frequency and phenotypes of APC and MUTYH mutations in 6,169 individuals undergoing genetic testing.

Inra JA, Steyerberg EW, Grover S, McFarland A, Syngal S, Kastrinos F.

Genet Med. 2015 Oct;17(10):815-21. doi: 10.1038/gim.2014.199. Epub 2015 Jan 15.


Familial colorectal cancer, beyond Lynch syndrome.

Stoffel EM, Kastrinos F.

Clin Gastroenterol Hepatol. 2014 Jul;12(7):1059-68. doi: 10.1016/j.cgh.2013.08.015. Epub 2013 Aug 17. Review.


History, genetics, and strategies for cancer prevention in Lynch syndrome.

Kastrinos F, Stoffel EM.

Clin Gastroenterol Hepatol. 2014 May;12(5):715-27; quiz e41-3. doi: 10.1016/j.cgh.2013.06.031. Epub 2013 Jul 23. Review.


Prediction models in Lynch syndrome.

Kastrinos F, Balmaña J, Syngal S.

Fam Cancer. 2013 Jun;12(2):217-28. doi: 10.1007/s10689-013-9632-0. Review.


Elevated risk of prostate cancer among men with Lynch syndrome.

Raymond VM, Mukherjee B, Wang F, Huang SC, Stoffel EM, Kastrinos F, Syngal S, Cooney KA, Gruber SB.

J Clin Oncol. 2013 May 10;31(14):1713-8. doi: 10.1200/JCO.2012.44.1238. Epub 2013 Mar 25.


Split dose and MiraLAX-based purgatives to enhance bowel preparation quality becoming common recommendations in the US.

Hillyer GC, Lebwohl B, Basch CH, Basch CE, Kastrinos F, Insel BJ, Neugut AI.

Therap Adv Gastroenterol. 2013 Jan;6(1):5-14. doi: 10.1177/1756283X12464100.


Shortened surveillance intervals following suboptimal bowel preparation for colonoscopy: results of a national survey.

Hillyer GC, Basch CH, Lebwohl B, Basch CE, Kastrinos F, Insel BJ, Neugut AI.

Int J Colorectal Dis. 2013 Jan;28(1):73-81. doi: 10.1007/s00384-012-1559-7. Epub 2012 Aug 12.


Prevalence and phenotypes of APC and MUTYH mutations in patients with multiple colorectal adenomas.

Grover S, Kastrinos F, Steyerberg EW, Cook EF, Dewanwala A, Burbidge LA, Wenstrup RJ, Syngal S.

JAMA. 2012 Aug 1;308(5):485-492. doi: 10.1001/jama.2012.8780.


Risk of colorectal adenomas and advanced neoplasia in Hispanic, black and white patients undergoing screening colonoscopy.

Lebwohl B, Capiak K, Neugut AI, Kastrinos F.

Aliment Pharmacol Ther. 2012 Jun;35(12):1467-73. doi: 10.1111/j.1365-2036.2012.05119.x. Epub 2012 Apr 29.


Gastroenterologists' perceived barriers to optimal pre-colonoscopy bowel preparation: results of a national survey.

Hillyer GC, Basch CH, Basch CE, Lebwohl B, Kastrinos F, Insel BJ, Neugut AI.

J Cancer Educ. 2012 Jun;27(3):526-32. doi: 10.1007/s13187-012-0364-x.


Knowledge of quality performance measures associated with endoscopy among gastroenterology trainees and the impact of a web-based intervention.

Thompson JS, Lebwohl B, Syngal S, Kastrinos F.

Gastrointest Endosc. 2012 Jul;76(1):100-6.e1-4. doi: 10.1016/j.gie.2012.01.019. Epub 2012 Mar 14.


Performance of PREMM(1,2,6), MMRpredict, and MMRpro in detecting Lynch syndrome among endometrial cancer cases.

Mercado RC, Hampel H, Kastrinos F, Steyerberg E, Balmana J, Stoffel E, Cohn DE, Backes FJ, Hopper JL, Jenkins MA, Lindor NM, Casey G, Haile R, Madhavan S, de la Chapelle A, Syngal S; Colon Cancer Family Registry.

Genet Med. 2012 Jul;14(7):670-80. doi: 10.1038/gim.2012.18. Epub 2012 Mar 8.


Screening patients with colorectal cancer for Lynch syndrome: what are we waiting for?

Kastrinos F, Syngal S.

J Clin Oncol. 2012 Apr 1;30(10):1024-7. doi: 10.1200/JCO.2011.40.7171. Epub 2012 Feb 21. No abstract available.


Comparison of the clinical prediction model PREMM(1,2,6) and molecular testing for the systematic identification of Lynch syndrome in colorectal cancer.

Kastrinos F, Steyerberg EW, Balmaña J, Mercado R, Gallinger S, Haile R, Casey G, Hopper JL, LeMarchand L, Lindor NM, Newcomb PA, Thibodeau SN, Syngal S; Colon Cancer Family Registry.

Gut. 2013 Feb;62(2):272-9. doi: 10.1136/gutjnl-2011-301265. Epub 2012 Feb 16.


Inherited colorectal cancer syndromes.

Kastrinos F, Syngal S.

Cancer J. 2011 Nov-Dec;17(6):405-15. doi: 10.1097/PPO.0b013e318237e408. Review.


The impact of suboptimal bowel preparation on adenoma miss rates and the factors associated with early repeat colonoscopy.

Lebwohl B, Kastrinos F, Glick M, Rosenbaum AJ, Wang T, Neugut AI.

Gastrointest Endosc. 2011 Jun;73(6):1207-14. doi: 10.1016/j.gie.2011.01.051. Epub 2011 Apr 8.


Survivors of childhood cancer have increased risk of gastrointestinal complications later in life.

Goldsby R, Chen Y, Raber S, Li L, Diefenbach K, Shnorhavorian M, Kadan-Lottick N, Kastrinos F, Yasui Y, Stovall M, Oeffinger K, Sklar C, Armstrong GT, Robison LL, Diller L.

Gastroenterology. 2011 May;140(5):1464-71.e1. doi: 10.1053/j.gastro.2011.01.049. Epub 2011 Mar 17.


The PREMM(1,2,6) model predicts risk of MLH1, MSH2, and MSH6 germline mutations based on cancer history.

Kastrinos F, Steyerberg EW, Mercado R, Balmaña J, Holter S, Gallinger S, Siegmund KD, Church JM, Jenkins MA, Lindor NM, Thibodeau SN, Burbidge LA, Wenstrup RJ, Syngal S.

Gastroenterology. 2011 Jan;140(1):73-81. doi: 10.1053/j.gastro.2010.08.021. Epub 2010 Aug 19. Erratum in: Gastroenterology. 2012 Nov;143(5):1399. Gastroenterology. 2012 Nov;143(5):1399.


Risk of pancreatic cancer in families with Lynch syndrome.

Kastrinos F, Mukherjee B, Tayob N, Wang F, Sparr J, Raymond VM, Bandipalliam P, Stoffel EM, Gruber SB, Syngal S.

JAMA. 2009 Oct 28;302(16):1790-5. doi: 10.1001/jama.2009.1529.


Calculation of risk of colorectal and endometrial cancer among patients with Lynch syndrome.

Stoffel E, Mukherjee B, Raymond VM, Tayob N, Kastrinos F, Sparr J, Wang F, Bandipalliam P, Syngal S, Gruber SB.

Gastroenterology. 2009 Nov;137(5):1621-7. doi: 10.1053/j.gastro.2009.07.039. Epub 2009 Jul 18.


Development and validation of a colon cancer risk assessment tool for patients undergoing colonoscopy.

Kastrinos F, Allen JI, Stockwell DH, Stoffel EM, Cook EF, Mutinga ML, Balmaña J, Syngal S.

Am J Gastroenterol. 2009 Jun;104(6):1508-18. doi: 10.1038/ajg.2009.135. Epub 2009 Apr 28.


ACP Journal Club. CT colonography had 90% sensitivity and 86% specificity for diagnosing large adenomas and cancer in asymptomatic adults.

Kastrinos F, Lebwohl B, Neugut AI.

Ann Intern Med. 2009 Feb 17;150(4):JC2-13. No abstract available.


Maybe a baby? Revisiting the effect of IBD on conception, pregnancy, and newborn outcomes.

Kastrinos F.

Inflamm Bowel Dis. 2009 Mar;15(3):475-7. doi: 10.1002/ibd.20662. No abstract available.


Phenotype comparison of MLH1 and MSH2 mutation carriers in a cohort of 1,914 individuals undergoing clinical genetic testing in the United States.

Kastrinos F, Stoffel EM, Balmaña J, Steyerberg EW, Mercado R, Syngal S.

Cancer Epidemiol Biomarkers Prev. 2008 Aug;17(8):2044-51. doi: 10.1158/1055-9965.EPI-08-0301.


Recently identified colon cancer predispositions: MYH and MSH6 mutations.

Kastrinos F, Syngal S.

Semin Oncol. 2007 Oct;34(5):418-24. Review.


Attitudes toward prenatal genetic testing in patients with familial adenomatous polyposis.

Kastrinos F, Stoffel EM, Balmaña J, Syngal S.

Am J Gastroenterol. 2007 Jun;102(6):1284-90. Epub 2007 Mar 13.


Intestinal malabsorption as a manifestation of obstructive sleep apnea.

Knox TA, Gazi T, Kastrinos F, White AC.

Dig Dis Sci. 2003 Jan;48(1):83-5. No abstract available.


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